 | H Reichelt |
Prominent publications by H Reichelt
One of the most striking properties of perfluorocarbons is their chemical inertness. Due to this, these compounds are said to be physiobiologically compatible. Therefore, they are suggested for a variety of medical uses including the one as component of blood substitutes. However, it was the blood substitute research, which revealed biological activities of perfluorocarbons. Some of these biological effects are described shortly.
| Also Ranks for: Blood Substitutes | chemically inert | variety medical | biological activities |
Dispersions of fluorocarbons (PFC's) made with phospholipids have unusual properties, e.g. very high stability, due to the formation of thermodynamically stable vesicles. They can be used for high PFC concentrations as well as e.g. for ESR imaging.
| Also Ranks for: Blood Substitutes |
Blood Substitutes Made on the Basis of Perfluorocarbons Inhibit Intracellular Energy Generation
[ PUBLICATION ]
Although perfluorocarbons (PFC) are chemically inert, toxic reactions are observed on using them as fluorocarbon emulsions in blood substitutes. Six to twelve hours after exchanging about half of the circulating blood of conscious rats pathobiochemical reactions occur despite a high interarterial oxygen pressure. They indicate the disturbance of intracellular energy generation, which is characterized by a decrease in ATP, increase in ADP, inorganic phosphate and potassium, increase in ...
H Reichelt: Influence Statistics
| Concept | World rank |
|---|---|
| wissenschaftliche aufgabe anforderungen | #3 |
| viele anforderungen blutersatzmittel | #3 |
| blutersatzmittel weiterentwicklung | #3 |
| wissenschaftliche aufgabe | #3 |
| anforderungen blutersatzmittel | #3 |
| viele anforderungen | #3 |
| fluorocarbons pfc | #3 |
| weiterentwicklung wissenschaftliche aufgabe | #3 |
| blutersatzmittel | #8 |
| fluorocarbons hemolysis | #83 |
Key People For Blood Substitutes
H Reichelt:Expert Impact
Concepts for whichH Reichelthas direct influence:Blood substitutes, Fluorocarbons pfc, Oxygen carriers, Fluorocarbon emulsions, Viele anforderungen, Anforderungen blutersatzmittel, Wissenschaftliche aufgabe, Blutersatzmittel weiterentwicklung.
H Reichelt:KOL impact
Concepts related to the work of other authors for whichfor which H Reichelt has influence:Contrast agents, Surface tension, Calvarial defects, Retinal toxicity, Membrane packing, Fluorinated dendrimers, Perfluorocarbon vapors.
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