• KOL
    • Estrogen Receptors
    • Wim Misdorp
    • Wim MISDORP: Influence Statistics

      Wim MISDORP

      Wim MISDORP

      The author is deceased | Department of Veterinary Pathology, State University, Utrecht, and Department of Pathology, University Hospital Nijmegen, The Netherlands | Department ...

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      Wim MISDORP:Expert Impact

      Concepts for whichWim MISDORPhas direct influence:Estrogen receptors,Mammary tumours,Canine tissues,Mammary tumors,Domestic animals,Congenital tumours,Dna ploidy,Growth hormone.

      Wim MISDORP:KOL impact

      Concepts related to the work of other authors for whichfor which Wim MISDORP has influence:Mammary tumors,Mast cell,Growth hormone,Diseases dogs,Human breast cancer.

      KOL Resume for Wim MISDORP

      Year
      2010

      The author is deceased

      Department of Pathobiology, Faculty of Veterinary Medicine, University of Utrecht, Utrecht, Netherlands

      2004

      Emeritus Professor of Veterinary Oncology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

      2003

      Faculty of Veterinary Medicine, Utrecht University, The Netherlands.

      2002

      Department of Veterinary Pathology, University of Utrecht, The Netherlands

      2000

      Department of Pathology, Veterinary School, University of Utrecht, Utrecht, The Netherlands

      1999

      Department of Pathology, Faculty of Veterinary Medicine, Utrecht University, Utrecht

      The Netherlands Cancer Institute, Antoni van Leeuwenhoekhuis, Amsterdam, The Netherlands

      1998

      Department of Pathology, Faculty of Veterinary Medicine, University of Utrecht, Netherlands

      1997

      Department of Pathology, Faculty of Veterinary Medicine, University of Utrecht. 3508 TD Utrecht, The Netherlands

      1996

      Faculty of Veterinary Medicine, University of Utrecht, The Netherlands.

      1995

      Department of Pathology, Faculty of Veterinary Medicine, University of Utrecht, P.O. Box 80.165, 3508 TD Utrecht, Netherlands

      1994

      Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, P.O. Box 80.154, 3508 TD, Utrecht, The Netherlands

      1993

      Department of Pathology, Faculty of Veterinary Medicine , University of Utrecht , Utrecht,

      1992

      Department of Veterinary Pathology, Faculty of Veterinary Medicine, State University, 3508 TD Utrecht, The Netherlands

      Afdeling Pathologie, Nederlands Kankerinstituut te Amsterdam, vakgroepen Geneeskunde van Gezelschapsdieren, Faculteit der Diergeneeskunde, Utrecht.

      1991

      Department of Pathology, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam.

      1990

      Department of Pathology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

      1989

      Department of Pathology, Faculty of Veterinary Medicine, State University of Utrecht, and The Netherlands Cancer Institute, Amsterdam, The Netherlands

      1988

      Department of Pathology, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

      1987

      Veterinary Faculty, State University, Utrecht, The Netherlands.

      1986

      Department of Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands

      1985

      Department of Pathology, Div. Clin. Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands

      1984

      Laboratory for Pathology, National Institute of Public Health and Environmental Hygiene, Bilthoven

      1983

      Department of Pathology, Antoni van Leeuwenhoekhuis, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

      1980

      Department of Pathology, Netherlands Cancer Institute, Amsterdam; and the Department of Pathology, Medical Faculty, University of Rotterdam, the Netherlands

      1979

      Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Division of Clinical Oncology, Plesmanlaan 121, Amsterdam, The Netherlands

      1976

      Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands

      1975

      Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

      1974

      Department of Pathology, Antoni van Leeuwenhoek-Huis, The Netherlands Cancer Institute, Amsterdam, The Netherlands

      1973

      Afdeling Pathologie, Nederlands Kankerinstituut, Amsterdam; Department of Pathology, Royal Veterinary College, London; Afdeling Pathologic Einnengasthuis and University or Amsterdam, Amsterdam; Department of Veterinary Paraclinical Sciences, University of Melbourne; Institut für Allgemeine Pathologie und Pathologische Anatomie der Tierärztlichen Fakultät der Universität München

      1972

      Afdeling Pathologic, Nedcrlands Kankerinstituut, Amsterdam; Department of Pathology, Royal Veterinary College, London; Afdeling Pathologie, Binnengasthuis and University of Amsterdam, Amsterdam; Department of Veterinary Paraclinical Sciences, University of Melbourne, Melbourne; Institut für Allgemeine Pathologie und Pathologische Anatomie der Tierärztlichen Fakultät der Universität München, München.

      1971

      Afdeling Pathologie, Nederlands Kankerinstituut, Amsterdam; Department of Pathology, Royal Veterinary College, London; Afdeling Pathologie, Binnengasthuis, Amsterdam; Department of Veterinary and Paraclinical Sciences, University of Melbourne, and Institut für Tierpathologie der Universität, München

      1970

      Brinklaan 148, Bussum. The Netherlands

      W. M

      N. P. K

      R. O

      1968

      From the Department of Pathology, Netherlands Cancer Institute, Amsterdam

      1967

      Department of Pathology, Netherlands Cancer Institute Amsterdam, Holland, The Netherland

      Aus der Universitätsklinik für Kleine Haustiere, Utrecht Direktor: Prof. Dr. G. H. B. Teunissen und der Pathologisch‐Anatomischen Abteilung des Niederländischen Krebsinstitutes Amsterdam Direktor: Prof. Dr. J. F. Hampe

      1965

      Antoni van Leeuwenhoek-Huis, Amsterdam C/Holland, Sarphatistraat 108

      Tierärzte in Amsterdam

      1964

      Istituto di Anatomia e Istologia Patologica, Centro di Microscopia Elettronica, Università di Bari

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      Sample of concepts for which Wim MISDORP is among the top experts in the world.
      Concept World rank
      teratomas special attention #1
      undescended testis horse #1
      17 dogs metastases #1
      dogs lumbosacral region #1
      mammary tumours types #1
      vimentin antiserum staining #1
      interstitial hamartomas #1
      carcino sarcoma #1
      vimentin antiserum #1
      33 primary #1
      primary spf #1
      amsterdam material #1
      45 bpl #1
      bitches progestins #1
      pct nonpct patients #1
      aneuploid g01 peaks #1
      counterpart anaplastic carcinoma #1
      netherlands pathological study #1
      varying parietal #1
      embryonic tumours teratomas #1
      progestins advanced age #1
      histological heterogeneity spf #1
      canine tissues immunoreactivity #1
      nonaffected mammary tissues #1
      comparative remarks situation #1
      sarcomas infiltrative growth #1
      carcinosarcomatous tumors #1
      malignant mixed tumour #1
      conditions dystocia #1
      felv blv #1
      autonomously growing #1
      impression adolescent adult #1
      temporal teratomas #1
      earlier appearance controls #1
      2 pigs review #1
      isolation autonomously #1
      amsterdam abattoir period #1
      tumours models #1
      woman sarcomas #1
      cats mammary tumors #1
      49 bpl #1
      congenital cases tumours #1
      tumors simple carcinomas #1
      lion comparative remarks #1
      female liposarcoma #1
      instance twin calves #1
      Sign-in to see all concepts, it's free!

      Prominent publications by Wim MISDORP

      KOL-Index: 8928

      A total of 30 horses with single or multiple sarcoid tumors of the skin were randomly divided into three treatment groups: (i) cryosurgical treatment, (ii) intralesional immunotherapy with a live BCG vaccine, (iii) intralesional immunotherapy with a BCG cell wall preparation. Complete tumour regression was obtained in all 10 crysurgically treated horses, in 6 of 10 live BCG treated horses, and in 7 of 10 BCG cell wall treated horses. One live BCG and 2 BCG cell wall treated horses showed ...

      Known for Bcg Immunotherapy | Equine Sarcoid | Cell Wall | Tumour Regression | 1 Animal
      KOL-Index: 8374

      Lymphocyte stimulation with Con A and specific immune reactivity to BCG (antibody formation to BCG and DTH reaction to PPD) were determined in BCG-treated, surgically treated and untreated cows with ocular squamous cell carcinoma. In tumor-bearing cows the Con A-induced proliferation of lymphocytes was reduced when compared to healthy controls. This suppression consisted of a reduced blastogenic response to Con A of lymphocytes from tumor-bearing cows, and the presence of a factor in the ...

      Known for Immune Reactivity | Squamous Cell | Eye Neoplasms | Antibodies Bcg | Antibody Formation
      KOL-Index: 8152

      Currently, prognostic and therapeutic determinations for canine cutaneous mast cell tumors (MCTs) are primarily based on histologic grade. However, the use of different grading systems by veterinary pathologists and institutional modifications make the prognostic value of histologic grading highly questionable. To evaluate the consistency of microscopic grading among veterinary pathologists and the prognostic significance of the Patnaik grading system, 95 cutaneous MCTs from 95 dogs were ...

      Known for Histologic Grading | Biological Behavior | Veterinary Pathologists | Highgrade Mcts | Cutaneous Mast
      KOL-Index: 7388

      This article reviews the literature on mast cells and tumours derived from mast cells in the dog. Mast cells play a central role in inflammatory and immune reactions. Mast cells, normal and neoplastic, contain and release important biologically active substances: heparin, histamine, eosinophilic chemotactic factor and proteolytic enzymes. Mast cell tumours occur in the dog, particularly in the boxer and related breeds, in the skin and less frequently in the intestines. Cytology usually ...

      Known for Mast Cells | Cell Tumours | Histologic Grading | Clinical Staging | Diseases Dogs
      KOL-Index: 7171

      Duct ectasias (n = 2) and different types of benign canine mammary tumours (n = 19) were studied immunohistochemically with monoclonal antibodies (MoAbs) directed against various human keratin types (K), alpha-smooth muscle actin, vimentin, and desmin. In the duct ectasias and in most tumours the epithelial structures revealed an inner and outer cell layer. The inner cell layer was characterized by labelling with K 7, 8, 18, 19 and mostly also with K 4 and/or K 10 MoAbs. The outer cell ...

      Known for Mammary Tumours | Smooth Muscle | Monoclonal Antibodies | Myoepithelial Cells | Immunohistochemical Features
      KOL-Index: 7136

      The role of progestins in the pathogenesis of breast cancer in women remains controversial. To advance this discussion, we report the demonstration and localization of progestin-induced biosynthesis of growth hormone (GH) in canine mammary gland tissue. Nontumorous mammary tissues and tumors, both benign and malignant, were obtained from private household dogs. Immunoreactive GH was localized in mammary epithelial cells and correlated with the presence of GH mRNA. Local synthesis of GH ...

      Known for Mammary Tumors | Growth Hormone | Gh Expression | Synthetic Progestins | Progesterone Receptors
      KOL-Index: 7064

      Normal canine mammary gland tissue was studied immunohistochemically with monoclonal antibodies (MoAbs) directed against various human keratin types, vimentin, desmin, and alpha-smooth muscle actin. Both ductal and alveolar luminal cells were immunoreactive with MoAbs recognizing respectively human keratins no. 7, 8, 18 and 19. In addition, some ductal luminal cells were labelled with a keratin 4 and a keratin 10 MoAb. Basal/myoepithelial cells were immunoreactive only with MoAbs ...

      Known for Monoclonal Antibodies | Muscle Actin | Canine Mammary Gland | Mammary Tissue | Vimentin Desmin
      KOL-Index: 6902

      Estrogen receptors (ER) were determined by both the biochemical dextran-coated charcoal (DCC-ER) and the immunohistochemical Avidin biotin-peroxidase complex (IHC-ER) methods in proliferative mammary lesions collected from 37 cats: 20 malignant tumors without metastasis at first presentation, seven malignant tumors with lung and/or lymph node metastases and 10 benign tumors and dysplasias. Total number of samples analyzed by both methods was 44. The DCC-ER method was applied to frozen ...

      Known for Estrogen Receptors | Mammary Gland | Immunohistochemical Analysis | Neoplasms Animal | Biochemical Assay
      KOL-Index: 6886

      Ten malignant canine mammary gland tumours and five metastases from three of these tumours were studied immunohistochemically with monoclonal antibodies (MoAbs) directed against different human keratin types (K), alpha-smooth muscle actin, vimentin, and desmin. In all tumours the neoplastic epithelium was rather homogeneously labelled with the keratin MoAbs RCK 102 (K 5 and 8) and CAM 5.2 (K 8). The adenocarcinomas (n = 5), the solid carcinomas (n = 2), and the carcinosarcoma (n = 1) ...

      Known for Mammary Tumours | Muscle Actin | Monoclonal Antibodies | Solid Carcinomas | Vimentin Desmin
      KOL-Index: 6704

      In a wide range of canine tissues the immunoreactivity with commercially available antisera against intermediate filament antigens viz. vimentin, desmin, glial fibrillary acidic protein (GFAP) and neurofilament proteins, was studied. In addition, the results of formalin and Carnoy fixation were compared. Carnoy fixation appeared to result in optimal reactivity for all antisera. Epithelial cells did not react with any of the antisera, with exception of ovarian surface epithelium, which ...

      Known for Vimentin Desmin | Immunohistochemical Study | Fibrillary Acidic | Epithelial Cells | Neurofilament Proteins
      KOL-Index: 6473

      Oestrogen (ER) and progestin receptors (PR) were measured in cytosols from histologically normal mammary tissues (n = 30), and in benign (n = 59) and malignant mammary lesions (n = 49) from female dogs. Receptor levels greater than or equal to 5 fmol mg-1 protein were considered positive. The presence of histologically normal mammary epithelium within specimens of primary tumours was noticed as a factor that may cause false-positive receptor results. Receptor levels in non-malignant ...

      Known for Mammary Tissue | Estrogen Receptors | Female Dogs | Receptor Status | Primary Tumours

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      The author is deceased | Department of Veterinary Pathology, State University, Utrecht, and Department of Pathology, University Hospital Nijmegen, The Netherlands | Department of Pathobiology, Faculty of Veterinary Medicine, University of Utrecht, Ut

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