Miki Shimizu

Miki Shimizu

Department Of Pediatrics And Child Neurology, Oita University Faculty Of Medicine, Oita, Japan

Direct Impact

Concepts for which Miki Shimizu has direct influence:

massive doses
benign familial neonatal epilepsy
epileptic characteristics
germline braf mutation
cardio‐facio‐cutaneous syndrome
open-lip schizencephaly
extensive porencephaly

External impact

Concepts related to the work of other authors for which Miki Shimizu has influence:

juvenile myelomonocytic leukemia
braf oncogene
preterm infants
central role
65 screened jmml
ras-raf-mek-erk-signaling pathway
exogenous stimuli

Prominent publications by Miki Shimizu

KOL-Index: 19 A male infant, born at 32 weeks gestation by cesarean because of hydrops fetalis, presented with multiple anomalies, such as sparse and curly scalp hair, absent eyebrows, frontal bossing, an atrial septal defect, pulmonary artery stenosis, and whole myocardial thickening. He was clinically diagnosed with cardio-facio-cutaneous (CFC) syndrome, and was confirmed to have a germline V-raf murine ...
Known for
Atrial Septal Defect | Mpn Braf | Cardio-Facio-Cutaneous Cfc Syndrome | Pulmonary Artery Stenosis
KOL-Index: 7 BACKGROUND: Barbiturates and benzodiazepines are the first-line anticonvulsants for neonatal seizures. However, in immature brains, those drugs may lead to paradoxical neuronal excitation. PATIENT: A patient with benign familial neonatal epilepsy developed epileptic encephalopathy after massive doses of phenobarbital that were followed by a continuous infusion of midazolam on postnatal day ...
Known for
Immature Brains | Seizure Thresholds | Uncoupling Phenomenon | Paradoxical Neuronal Excitation
KOL-Index: 6 The epileptic characteristics and their differences in patients with porencephaly and schizencephaly were, respectively, evaluated. Eleven patients with porencephaly and eight patients with schizencephaly were retrospectively enrolled in this study. Five of the six patients with extensive porencephaly and all five patients with open-lip schizencephaly had been suffering from various types of ...
Known for
Extensive Widespread Defective Lesions | Monotherapy Drug | Larger-Number Polytherapy | Epileptogenesis
KOL-Index: 4 We subclassified schizencephaly based on the association with optic nerve hypoplasia (ONH) and the absence of the septum pellucidum (ASP), and then characterized their clinical presentation and prognosis. The subjects of our study consisted of 10 cases with a mean age at the final evaluation of 10 years 3 months (range, 7 months to 25 years). The subclassification of schizencephaly consisted ...
Known for
Optic Dysplasia | Early Fetal Brain Injury | 7 Months

Department of Pediatrics and Child Neurology, Oita University Faculty of Medicine, Oita, Japan

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