Prominent publications by Narinder Kapur
Transient Epileptic Amnesia (TEA) is a form of temporal lobe epilepsy associated with ictal and interictal memory disturbance. Some patients with TEA exhibit Accelerated Long-term Forgetting (ALF), in which memory for verbal and non-verbal material is retained normally over short delays but fades at an unusually rapid rate over days to weeks. This study addresses three questions about ALF in TEA: (i) whether real-life events undergo ALF in a similar fashion to laboratory-based stimuli; ...
|Also Ranks for: Transient Epileptic Amnesia | accelerated forgetting | patients tea | alf memory | reallife events|
[ PUBLICATION ]
Transient epileptic amnesia (TEA) is a recently recognised form of epilepsy of which the principle manifestation is recurrent, transient episodes of isolated memory loss. In addition to the amnesic episodes, many patients describe significant interictal memory difficulties. Performance on standard neuropsychological tests is often normal. However, two unusual forms of memory deficit have recently been demonstrated in TEA: (i) accelerated long-term forgetting (ALF): the excessively rapid ...
|Also Ranks for: Memory Deficits | transient epileptic amnesia | brain atrophy | manual volumetry | epilepsy female humans|
[ PUBLICATION ]
The first comprehensive in vivo documentation of the long term profile of pathological and spared tissue is described in a group of 10 patients with a diagnosis of herpes simplex encephalitis, who were left with memory difficulties as a major residual sequel of their condition. With a dedicated MRI protocol, which included high resolution images of temporal lobe and limbic system areas, data are provided on structures that have recently gained importance as anatomical substrates for ...
|Also Ranks for: Magnetic Resonance | herpes simplex encephalitis | temporal lobe | neuropsychological profile | limbic areas|
Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial (DESCANT)): study protocol for a randomised controlled trial
[ PUBLICATION ]
BackgroundThere is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial (DESCANT) will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention ...
|Also Ranks for: Cognitive Aids | early stage | people dementia | randomised controlled trial | quality life|
The use of a wearable camera, SenseCam, as a pictorial diary to improve autobiographical memory in a patient with limbic encephalitis: A preliminary report
[ PUBLICATION ]
This case study describes the use of a wearable camera, SenseCam, which automatically captures several hundred images per day, to aid autobiographical memory in a patient, Mrs B, with severe memory impairment following limbic encephalitis. By using SenseCam to record personally experienced events we intended that SenseCam pictures would form a pictorial diary to cue and consolidate autobiographical memories. After wearing SenseCam, Mrs B plugged the camera into a PC which uploaded the ...
|Also Ranks for: Autobiographical Memory | limbic encephalitis | wearable camera | sensecam images | written diary|
Safety in aviation has often been compared with safety in healthcare. Following a recent article in this journal, the UK government set up an Independent Patient Safety Investigation Service, to emulate a similar well-established body in aviation. On the basis of a detailed review of relevant publications that examine patient safety in the context of aviation practice, we have drawn up a table of comparative features and a conceptual framework for patient safety. Convergence and ...
|Also Ranks for: Patient Safety | aviation healthcare | human factors | detailed review | conceptual framework|
There has been considerable debate as to whether the hippocampus and perirhinal cortex may subserve both memory and perception. We administered a series of oddity tasks, in which subjects selected the odd stimulus from a visual array, to amnesic patients with either selective hippocampal damage (HC group) or more extensive medial temporal damage, including the perirhinal cortex (MTL group). All patients performed normally when the stimuli could be discriminated using simple visual ...
|Also Ranks for: Medial Temporal | faces objects | perirhinal cortex | mtl patients | magnetic resonance|
SenseCam improves memory for recent events and quality of life in a patient with memory retrieval difficulties
[ PUBLICATION ]
A wearable camera that takes pictures automatically, SenseCam, was used to generate images for rehearsal, promoting consolidation and retrieval of memories for significant events in a patient with memory retrieval deficits. SenseCam images of recent events were systematically reviewed over a 2-week period. Memory for these events was assessed throughout and longer-term recall was tested up to 6 months later. A written diary control condition followed the same procedure. The SenseCam ...
|Also Ranks for: Sensecam Images | memory retrieval | written diary | wearable camera | quality life|
Using positron emission tomography, we examined cerebral blood flow changes in human subjects whilst engaged in the visual processing of face stimuli. A task requiring anterograde memory of faces was compared with a control task involving simple gender classification--considered an automatic process that did not require any significant memory component. A second task requiring recognition of famous politicians' faces, and therefore involving long-term "semantic" memory, was also ...
|Also Ranks for: Pet Study | memory faces | control task | human hippocampal formation | hippocampal regions|
Item recognition is less impaired than recall and associative recognition in a patient with selective hippocampal damage
[ PUBLICATION ]
This article explores the recall, item recognition, and associative recognition memory of patient B.E., whose pattern of retrograde amnesia was reported by Kapur and Brooks (1999; Hippocampus 9:1-8). Structural magnetic resonance imaging (MRI) has shown that B.E. has bilateral damage restricted to the hippocampus. The structural damage he had sustained was accompanied by bilateral hypoperfusion of the temporal lobe, revealed by positron emission tomography (PET), and which single photon ...
|Also Ranks for: Associative Recognition | anterograde amnesia | temporal lobe | hippocampal damage | remember procedure|
[ PUBLICATION ]
OBJECTIVE: Transient amnesia can be the principal manifestation of epilepsy. This diagnosis, however, is seldom suspected by clinicians and remains controversial. The amnestic attacks are often associated with persistent memory complaints. This study was designed to provide the first description of transient epileptic amnesia in a substantial series of patients.
METHODS: Fifty patients were recruited over 18 months using the following diagnostic criteria: (1) recurrent, witnessed ...
|Also Ranks for: Transient Epileptic Amnesia | patients accelerated forgetting | normal performance | epilepsy syndrome | amnestic episodes|
Recent animal studies suggest that the medial temporal lobe (MTL), which is thought to subserve memory exclusively, may support non-mnemonic perceptual processes, with the hippocampus and perirhinal cortex contributing to spatial and object perception, respectively. There is, however, no support for this view in humans, with human MTL lesions causing prominent memory deficits in the context of apparently normal perception. We assessed visual discrimination in amnesic cases to reveal that ...
|Also Ranks for: Perceptual Deficits | temporal lobe | magnetic resonance | perirhinal cortex | visual discrimination|
Retrograde amnesia in neurological disorders is a perplexing and fascinating research topic. The severity of retrograde amnesia is not well correlated with that of anterograde amnesia, and there can be disproportionate impairments of either. Within retrograde amnesia, there are various dissociations which have been claimed-for example, between the more autobiographical (episodic) and more semantic components of memory. However, the associations of different types of retrograde amnesia ...
|Also Ranks for: Retrograde Amnesia | episodic memories | neurological disorders | studies forms | psychogenic factors|
This PET study has revealed the neural system involved in implicit face, proper-name and object name processing during an explicit visual 'same' versus 'different' matching task. Within the identified system, some areas were equally active irrespective of modality (faces or names) or type of stimuli (famous and non-famous) while other areas exhibited differential effects. Our findings support the hypothesis that faces and names involve differential pre-semantic processing prior to ...
|Also Ranks for: Neural Systems | visual tomography | faces names | famous stimuli | pet study|
[ PUBLICATION ]
Transient epileptic amnesia is a form of temporal lobe epilepsy in which sufferers often complain of irretrievable loss of remote memories. We used a broad range of memory tests to clarify the extent and nature of the remote memory deficits in patients with transient epileptic amnesia. Performance on standard tests of anterograde memory was normal. In contrast, there was a severe impairment of memory for autobiographical events extending across the entire lifespan, providing evidence for ...
|Also Ranks for: Transient Epileptic Amnesia | remote memory | standard tests | temporal lobe epilepsy | brain regions|
Narinder Kapur: Influence Statistics
|dense autobiographical amnesia||#1|
|anterograde memory functioning||#1|
|methodological caveats amnesia||#1|
|memory news events||#1|
|remembering norman schwarzkopf||#1|
|human memory possibility||#1|
|remote memory deficits||#1|
|diagnostic dilemma causality||#1|
|transient amnesic attacks||#1|
|marked retrograde amnesia||#1|
|wada test procedures||#1|
|relation published cases||#1|
|limbicdiencephalic structures neocortex||#1|
|gradual transfer memory||#1|
|analysis selective amnesia||#1|
|safety crm training||#1|
|variable involvement limbic||#1|
|focal pathology patient||#1|
|case transient amnesia||#1|
|evidence greater role||#1|
|preoperative seizure activity||#1|
|healthcare incident analysis||#1|
|incident analysis debrief||#1|
|memory loss finding||#1|
|focal phenomenon cases||#1|
|tea global amnesia||#1|
|unconscious processes episode||#1|
|clear epileptic features||#1|
Key People For Retrograde Amnesia
Narinder Kapur:Expert Impact
Concepts for whichNarinder Kapurhas direct influence:Retrograde amnesia, Focal retrograde amnesia, Memory aids, Transient epileptic amnesia, Temporal lobe, Neuropsychological profile, Memory loss, Episodic memories.
Narinder Kapur:KOL impact
Concepts related to the work of other authors for whichfor which Narinder Kapur has influence:Episodic memory, Temporal lobe, Retrograde amnesia, Perirhinal cortex, Semantic dementia, Magnetic resonance, Neuropsychological tests.
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