• Disease
  • Clozapine
  • Clozapine Treatment
  • Joseph K Stanilla

    Prominent publications by Joseph K Stanilla

    KOL Index score: 9048

    BACKGROUND: Akathisia has been reported to predict more severe symptoms and poorer treatment response to typical neuroleptics among patients with schizophrenia. Akathisia has also been associated with symptom exacerbation. This study addressed four questions: 1) Does akathisia predict greater severity in global psychopathology? 2) Is this effect global or specific? 3) Does clozapine treatment alter this relationship? 4) Does severity of psychopathology covary with the level of ...

    Also Ranks for: Akathisia Psychopathology |  clozapine treatment |  16 weeks |  patients schizophrenia |  rating scale
    KOL Index score: 6897

    OBJECTIVE: This study explored the relative efficacy of three different doses of clozapine.

    METHOD: Fifty patients who met Kane et al.'s criteria for treatment-refractory schizophrenia or schizoaffective disorder were studied. All subjects were randomly assigned to 100, 300, or 600 mg/day of clozapine for 16 weeks of double-blind treatment. Forty-eight patients completed this first 16 weeks. Of the 50 patients, 36 went on to second and third 16-week trials of double-blind treatment at ...

    Also Ranks for: Clozapine Dose |  chronic schizophrenia |  600 day |  response treatment |  schizoaffective disorder
    KOL Index score: 5008

    This cross-sectional survey attempts to establish the prevalence of polydipsia and water intoxication at a state hospital (N = 360) using staff diagnosis, specific gravity of the urine (SPGU), weight changes, and chart review. There were 150 [42%, 95% confidence interval (CI) 37-47%] patients diagnosed as polydipsic by the staff or by SPGU. At least 93 (26%, CI 21-30%) had primary polydipsia not explained by other causes. Chart review identified 17 (5%, CI 3-7%) patients with a history ...

    Also Ranks for: Water Intoxication |  primary polydipsia |  psychiatric hospital |  heavy smoking |  specific gravity
    KOL Index score: 2542

    Neuroleptic-induced tardive dyskinesia (TD) negatively impacts the quality of life for persons with schizophrenia. While no satisfactory treatment is available for TD, a growing body of literature suggests the efficacy of clozapine in reducing TD. This paper describes the efficacy of clozapine in reducing TD in relation to the variables of treatment duration and dosage. Eighteen schizophrenic patients were categorized as with and five as without probable TD, and a pattern of reversible ...

    Also Ranks for: Tardive Dyskinesia |  quality life |  effects clozapine |  schizophrenic patients |  neuroleptic induced
    KOL Index score: 2394

    Misidentification syndromes represent false, delusionally-based identification of self and/or others. These are variants of the Capgras Syndrome. Although the frequency of misidentification syndromes in schizophrenic populations has not yet been established, the authors believe this syndrome is more prevalent than previously described. Seven of twenty-five (28%) consecutive patients admitted to a chronic clozapine unit with a variant of misidentification syndrome will be described. Their ...

    Also Ranks for: Misidentification Syndrome |  schizophrenia schizophrenic |  psychotic disorders |  adult capgras |  delusions female
    KOL Index score: 1852

    The diurnal and weekly variability of tardive dyskinesia (TD) was assessed instrumentally by digital image processing. Weekly assessments were obtained in ten patients over a 6-week period. In six of the ten patients, assessments were obtained four times over a single 12-h period. Results indicate that TD movements measured by instrumental assessment vary from week to week and throughout the day. Factors that appear to have affected the variability were changes in medications and the ...

    Also Ranks for: Tardive Dyskinesia |  digital image |  induced female |  6 week
    KOL Index score: 1239
    Also Ranks for: Clozapine Levels |  antipsychotic agents |  substance withdrawal |  syndrome adult
    KOL Index score: 834
    Also Ranks for: Clozapine Therapy |  epilepsies myoclonic


    Joseph K Stanilla: Influence Statistics

    Sample of concepts for which Joseph K Stanilla is among the top experts in the world.
    Concept World rank
    hyponatremia psychosis #5
    risk factors polydipsia #5
    crossover anova #5
    bprsa total scores #5
    600300100 day #5
    standardized casecontrol studies #5
    male nonschizophrenic patients #5
    exhaustive collections clinical #5
    staff spgu #5
    clozapine dose response #5
    case polydipsia #5
    higher poorer values #6
    clozapine withdrawal symptoms #7
    16week trials #7
    600 day clozapine #7
    variance anova comparison #7
    spgu #7
    16week condition #8
    clozapine 16 weeks #8
    anova bprs #8
    responded 600 #8
    subjects 600 day #8
    treatment polydipsia #9
    smoking polydipsia #10
    smoking nonschizophrenic #10
    akathisia psychopathology #11
    hyponatremia schizophrenic #11
    responded 16 #12
    longterm psychiatric hospital #12
    polydipsiahyponatremia #16
    exhaustive collections #16
    clozapine 16 #16
    polydipsia water intoxication #17
    100mg day dose #20
    hyponatremia psychiatric patients #21
    hyponatremia polydipsia #23
    staff diagnosis #24
    longitudinal identification #25
    clozapine drinking #25
    low doses clozapine #26
    chisquare comparison #29
    clozapine tardive dyskinesia #31
    polydipsia water #32
    schizophrenia extended #34
    misidentification syndrome #35
    93 26 #36
    clozapine delirium #37
    intoxication long #37
    intoxication state #39
    paranoid substance #39

    Key People For Clozapine Treatment

    Top KOLs in the world
    Herbert Yale Meltzer
    major depression antipsychotic drugs weight gain
    John Michael Kane
    tardive dyskinesia patients schizophrenia bipolar disorder
    Jeffrey A MD Lieberman
    tardive dyskinesia weight gain episode schizophrenia
    Gilbert Honigfeld
    clozapine therapy psychiatric patients multicenter trial
    Jack Singer
    neuroleptic nonresponders multicenter trial chlorpromazine treatment
    David Michael Taylor
    atypical antipsychotics clozapine treatment serotonin syndrome

    Joseph K Stanilla:Expert Impact

    Concepts for whichJoseph K Stanillahas direct influence:Clozapine treatment,  Tardive dyskinesia,  Water intoxication,  Clozapine withdrawal,  State hospital,  Psychiatric patients,  Psychiatric hospitals,  Extrapyramidal symptoms.

    Joseph K Stanilla:KOL impact

    Concepts related to the work of other authors for whichfor which Joseph K Stanilla has influence:Cigarette smoking,  Patients schizophrenia,  Nicotine dependence,  Mental illness,  Atypical antipsychotics,  Tardive dyskinesia,  Primary polydipsia.



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    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA (JKS) | Allegheny University of the Health Sciences, USA | Department of Psychiatry, Allegheny University, Norristown State Hospital, Pa. 19401, USA. | Medical Coll