Prominent publications by Bernard Iung

KOL Index score: 17178

OBJECTIVES: We sought to compare 3 methods of measurements of the aortic annulus, transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and multislice computed tomography (MSCT), and to evaluate their potential clinical impact on transcatheter aortic valve implantation (TAVI) strategy.

BACKGROUND: Exact measurement of the aortic annulus is critical for a patient's selection and successful implantation.

METHODS: Annulus diameter was measured using TTE, TEE, and ...

Also Ranks for: Aortic Annulus |  tte tee |  tavi strategy |  valve implantation |  agreement msct
KOL Index score: 16842

BACKGROUND: Transcatheter aortic valve replacement (TAVR) is standard therapy for patients with severe aortic stenosis who are at high surgical risk. However, national data regarding procedural characteristics and clinical outcomes over time are limited.

OBJECTIVES: The aim of this study was to assess nationwide performance trends and clinical outcomes of TAVR during a 6-year period.

METHODS: TAVRs performed in 48 centers across France between January 2013 and December 2015 were ...

Also Ranks for: France Tavi |  aortic valve |  temporal trends |  pacemaker implantation |  surgical risk
KOL Index score: 14958

OBJECTIVE: The purpose of the present study was to evaluate the prognostic implications of perioperative B-type natriuretic peptide (BNP) and cardiac troponin I concentrations in patients undergoing cardiopulmonary bypass for cardiac surgery.

DESIGN: Prospective observational study.

SETTING: Biochemistry laboratory and surgical care unit in a university hospital.

PATIENTS: A total of 92 consecutive patients undergoing elective coronary artery (43 patients) or valve surgery (49 ...

Also Ranks for: Cardiac Surgery |  natriuretic peptide |  day patients |  independent predictors |  year mortality
KOL Index score: 13395

Echocardiography plays a key role in the diagnosis of infective endocarditis (IE) but can be inconclusive in patients in whom prosthetic valve endocarditis (PVE) is suspected. The incremental diagnostic value of (18)F-FDG PET and radiolabeled leukocyte scintigraphy in IE patients has already been reported. The aim of this study was to compare the respective performance of (18)F-FDG PET and leukocyte scintigraphy for the diagnosis of PVE in 39 patients.

METHODS: (18)F-FDG PET and ...

Also Ranks for: Fdg Pet |  valve endocarditis |  leukocyte scintigraphy |  diagnosis pve |  patients definite
KOL Index score: 13146

AIMS: Transcatheter aortic valve implantation is a therapeutic alternative for high-surgical-risk patients with severe symptomatic aortic stenosis. Two models of prosthesis are currently commercialized in France, which can be implanted either via a transarterial or a transapical approach. The aim of the study was to evaluate in a national French registry the early safety and efficacy of transcatheter aortic valve replacement (AVR) using either the Edwards SAPIEN™ or CoreValve™ in ...

Also Ranks for: Aortic Valve |  edwards sapien |  1 month |  prosthesis implantation |  highsurgicalrisk patients
KOL Index score: 12889

BACKGROUND: In patients who have chronic heart failure with reduced left ventricular ejection fraction, severe secondary mitral-valve regurgitation is associated with a poor prognosis. Whether percutaneous mitral-valve repair improves clinical outcomes in this patient population is unknown.

METHODS: We randomly assigned patients who had severe secondary mitral regurgitation (defined as an effective regurgitant orifice area of >20 mm2 or a regurgitant volume of >30 ml per beat), a left ...

Also Ranks for: Percutaneous Repair |  medical treatment |  heart failure |  secondary mitral |  hazard ratio
KOL Index score: 12475

BACKGROUND: Pulmonary hypertension (PH) is associated with poor prognosis in patients with severe aortic stenosis. The aim of this multicenter study was to describe clinical outcome after transcatheter aortic valve implantation.

METHODS AND RESULTS: The FRANCE 2 Registry included all patients undergoing transcatheter aortic valve implantation in France in 2010 and 2011. Patients were divided into 3 groups depending on systolic pulmonary artery pressure (sPAP) estimated in transthoracic ...

Also Ranks for: Aortic Stenosis |  valve implantation |  pulmonary hypertension |  mm hg |  prognostic implications
KOL Index score: 12026

OBJECTIVES: The aim of this study was to assess prosthesis/annulus discongruence and its impact on the occurrence of significant aortic regurgitation (AR) immediately after transcatheter aortic valve implantation (TAVI).

BACKGROUND: Paravalvular AR might occur after TAVI, but its determinants remain unclear.

METHODS: Comprehensive echocardiographic examinations were performed in 74 patients who underwent TAVI with a balloon expandable device. Congruence between annulus and device was ...

Also Ranks for: Aortic Valve |  annulus discongruence |  paravalvular tavi |  prosthesis size |  implantation impact
KOL Index score: 11968

BACKGROUND: Transcatheter aortic valve replacement (TAVR) has emerged as an alternative to surgical aortic valve replacement (SAVR), but unbiased data regarding evolution of the treatment of patients with aortic stenosis at the nationwide level are scarce.

OBJECTIVES: This study sought to evaluate the number of aortic valve replacements (AVRs) performed in France, changes over time, and the effect of the adoption of TAVR.

METHODS: Based on a French administrative hospital-discharge ...

Also Ranks for: Aortic Valve |  savr tavr |  female france |  patients age |  nationwide level
KOL Index score: 11699

BACKGROUND: Valvular heart disease (VHD) is an important cause of mortality and morbidity and has been subject to important changes in management. The VHD II survey was designed by the EURObservational Research Programme of the European Society of Cardiology to analyze actual management of VHD and to compare practice with guidelines.

METHODS: Patients with severe native VHD or previous valvular intervention were enrolled prospectively across 28 countries over a 3-month period in 2017. ...

Also Ranks for: Valvular Heart |  aortic stenosis |  mitral regurgitation |  native vhd |  symptomatic patients
KOL Index score: 11584

BACKGROUND: Cardiac disease is 1 of the major causes of maternal mortality. We studied pregnancy outcomes in women with rheumatic mitral valve disease.

METHODS: The Registry of Pregnancy and Cardiac Disease is an international prospective registry, and consecutive pregnant women with cardiac disease were included. Pregnancy outcomes in all women with rheumatic mitral valve disease and no prepregnancy valve replacement is described in the present study (n=390). A maternal cardiac event ...

Also Ranks for: Pregnancy Outcomes |  valve disease |  heart failure |  rheumatic mitral |  women cardiac
KOL Index score: 11388

OBJECTIVES: The aim of this study was to determine baseline characteristics and clinical outcomes of patients with pre-existing atrial fibrillation (AF) and of patients who presented with new-onset AF after transcatheter aortic valve implantation (TAVI).

BACKGROUND: Little is known regarding the impact of AF after TAVI.

METHODS: The FRANCE-2 registry included all patients undergoing TAVI (N = 3,933) in France in 2010 and 2011. New-onset AF was defined as the occurrence of AF ...

Also Ranks for: Baseline Characteristics |  patients tavi |  valve implantation |  onset atrial |  higher rate
KOL Index score: 11180

BACKGROUND: Measurement of the degree of aortic valve calcification (AVC) using electron beam computed tomography (EBCT) is an accurate and complementary method to transthoracic echocardiography (TTE) for assessment of the severity of aortic stenosis (AS). Whether threshold values of AVC obtained with EBCT could be extrapolated to multislice computed tomography (MSCT) was unclear and AVC diagnostic value in patients with low ejection fraction (EF) has never been specifically ...

Also Ranks for: Aortic Valve Calcification |  haemodynamic severity |  ava avc |  low ejection fraction |  multislice computed
KOL Index score: 11107

AIMS: Indications for surgery in acute infective endocarditis (IE) are detailed in guidelines, but their application is not well known. We analysed the agreement between the patient's attending physicians and European Society of Cardiology guidelines regarding indications for surgery. We also assessed whether surgery was performed in patients who had an indication.

METHODS AND RESULTS: From the 2008 prospective population-based French survey on IE, 303 patients with definite left-sided ...

Also Ranks for: Cardiac Surgery |  patients indication |  acute phase |  infective endocarditis |  european society

Key People For Aortic Valve

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Bernard Iung:Expert Impact

Concepts for whichBernard Iunghas direct influence:Aortic valve,  Infective endocarditis,  Mitral valve,  Aortic stenosis,  Mitral stenosis,  Valvular heart disease,  Transcatheter aortic,  Heart valve.

Bernard Iung:KOL impact

Concepts related to the work of other authors for whichfor which Bernard Iung has influence:Heart failure,  Aortic valve,  Infective endocarditis,  Mitral regurgitation,  Atrial fibrillation,  Cardiac surgery.



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Cardiology Department, Bichat Hospital, AP-HP, Paris, France. | MD, PhD, Hôpital Universitaire Bichat, Université de Paris, France | Université de Paris and Institut National de la Santé et de la Recherche Scientifique 1148, Paris, France. | Cardiolo