• Disease
  • Cortical
  • Cortical Reorganization
  • Edward Taub

    Prominent publications by Edward Taub

    KOL Index score: 14577

    CONTEXT: Single-site studies suggest that a 2-week program of constraint-induced movement therapy (CIMT) for patients more than 1 year after stroke who maintain some hand and wrist movement can improve upper extremity function that persists for at least 1 year.

    OBJECTIVE: To compare the effects of a 2-week multisite program of CIMT vs usual and customary care on improvement in upper extremity function among patients who had a first stroke within the previous 3 to 9 months.

    DESIGN AND ...

    Also Ranks for: Upper Extremity Function |  9 months |  cimt patients |  movement therapy |  1 year
    KOL Index score: 10561

    BACKGROUND: Constraint-Induced Movement therapy (CI therapy) is shown to reduce disability, increase use of the more affected arm/hand, and promote brain plasticity for individuals with upper extremity hemiparesis post-stroke. Randomized controlled trials consistently demonstrate that CI therapy is superior to other rehabilitation paradigms, yet it is available to only a small minority of the estimated 1.2 million chronic stroke survivors with upper extremity disability. The current ...

    Also Ranks for: Upper Extremity |  comparative effectiveness |  outpatient stroke |  quality life |  video game rehabilitation
    KOL Index score: 10233

    In this laboratory we have developed a set of techniques that randomized controlled studies and a multisite randomized controlled trial have shown can substantially reduce the motor deficit of adult patients with mild to severe chronic strokes. Equivalent results have been obtained with adult patients after traumatic brain injury and brain resection. The basic technique, termed Constraint-Induced Movement therapy or CI therapy was derived directly from basic research with monkeys with ...

    Also Ranks for: Young Children |  6 months |  extremity motor |  life situation |  movement therapy
    KOL Index score: 10115

    BACKGROUND: The aim of constraint-induced movement therapy (CIMT) is to promote use of a limb that is functionally impaired after a stroke. In one form of CIMT to treat upper limb impairment, use of the less severely affected arm is restricted for many hours each weekday over 2 consecutive weeks. The EXCITE trial has previously shown the efficacy of this intervention for patients 3-9 months poststroke who were followed-up for the next 12 months. We assessed the retention of improvements ...

    Also Ranks for: Upper Limb |  stroke survivors |  movement therapy |  function restraint |  12 months
    KOL Index score: 9637

    The causes underlying phantom limb pain are still unknown. Recent studies on the consequences of nervous system damage in animals and humans reported substantial reorganization of primary somatosensory cortex subsequent to amputation, and one study showed that cortical reorganization is positively correlated with phantom limb pain. This paper examined the hypothesis of a functional relationship between cortical reorganization and phantom limb pain. Neuroelectric source imaging was used ...

    Also Ranks for: Cortical Reorganization |  phantom limb pain |  regional anesthesia |  somatosensory cortex |  image processing
    KOL Index score: 9379

    To date, single voxel spectroscopy (SVS) is the most commonly used MRS technique. SVS is relatively easy to use and provides automated and immediate access to the resulting spectra. However, it is also limited in spatial coverage. A new and very promising MRS technique allows for whole-brain MR spectroscopic imaging (WB-MRSI) with much improved spatial resolution. Establishing the reproducibility of data obtained using SVS and WB-MRSI is an important first step for using these techniques ...

    Also Ranks for: Single Voxel Spectroscopy |  magnetic resonance |  wb mrsi |  metabolite quantification |  healthy adults
    KOL Index score: 9269

    OBJECTIVE: To investigate the relationship of white matter integrity and path of the corticospinal tract (CST) on arm function before and after constraint-induced (CI) movement therapy in children with hemiparetic cerebral palsy (CP) and adults with chronic stroke.

    DESIGN: Study 1 used a multiple-baseline pre-post design. Study 2 was a randomized controlled trial.

    SETTING: Outpatient rehabilitation laboratory.

    PARTICIPANTS: Study 1 included children with hemiparetic CP (n=10; mean age ± ...

    Also Ranks for: Cerebral Palsy |  chronic stroke |  tensor imaging |  induced movement |  white matter integrity
    KOL Index score: 9151

    BACKGROUND AND PURPOSE: Injury-induced cortical reorganization is a widely recognized phenomenon. In contrast, there is almost no information on treatment-induced plastic changes in the human brain. The aim of the present study was to evaluate reorganization in the motor cortex of stroke patients that was induced with an efficacious rehabilitation treatment.

    METHODS: We used focal transcranial magnetic stimulation to map the cortical motor output area of a hand muscle on both sides in 13 ...

    Also Ranks for: Induced Cortical |  hand muscle |  stroke humans |  motor performance |  paretic limb
    KOL Index score: 8926

    OBJECTIVE: Constraint-Induced Movement (CI) therapy has been found to be a promising treatment for substantially increasing the use of extremities affected by such neurologic injuries as stroke and traumatic brain injury in adults. The purpose of this study was to determine the applicability of this intervention to young children with cerebral palsy.

    METHODS: A randomized, controlled clinical trial of pediatric CI therapy in which 18 children with diagnosed hemiparesis associated with ...

    Also Ranks for: Pediatric Therapy |  children cerebral palsy |  6 months |  induced movement |  moreaffected arm
    KOL Index score: 8869

    BACKGROUND AND PURPOSE: In research on Constraint-Induced Movement (CI) therapy, a structured interview, the Motor Activity Log (MAL), is used to assess how stroke survivors use their more-impaired arm outside the laboratory. This article examines the psychometrics of the 14-item version of this instrument in 2 chronic stroke samples with mild-to-moderate upper-extremity hemiparesis.

    METHODS: Participants (n=41) in the first study completed MALs before and after CI therapy or a placebo ...

    Also Ranks for: Motor Activity Log |  qom scale |  stroke survivors |  internal consistency |  impaired arm
    KOL Index score: 8629

    OBJECTIVE: To examine the reliability of the Wolf Motor Function Test (WMFT) for assessing upper extremity motor function in adults with hemiplegia.

    DESIGN: Interrater and test-retest reliability.

    SETTING: A clinical research laboratory at a university medical center.

    PATIENTS: A sample of convenience of 24 subjects with chronic hemiplegia (onset >1yr), showing moderate motor impairment.

    INTERVENTION: The WMFT includes 15 functional tasks. Performances were timed and rated by using a ...

    Also Ranks for: Functional Ability |  function test |  internal consistency |  wolf motor |  assessing upper
    KOL Index score: 8548

    Research from the present laboratory with adult stroke patients showed that structural neuroplastic changes are correlated with clinical improvements due to constraint-induced movement (CI) therapy. This pilot study evaluated whether comparable changes occur in children receiving CI therapy. Ten children (6 boys) with congenital hemiparesis (mean age: 3 years, 3 months) underwent MRI scans 3 weeks before, immediately before, and immediately after receiving 3 weeks of CI therapy. ...

    Also Ranks for: Cerebral Palsy |  movement therapy |  3 weeks |  motor improvement |  gray matter
    KOL Index score: 8512

    OBJECTIVE: To continue and expand determination of the reliability, validity, and sensitivity to change of the Arm Motor Ability Test (AMAT), an instrument for assessing deficits in activities of daily living (ADL).

    DESIGN: The AMAT was administered twice to patients, with an interest interval of either 1 or 2 weeks, by one of two examiners assigned to patients in counterbalanced order. Patients' interest intervals and scores on the arm portion of the Motricity Index was unknown to the ...

    Also Ranks for: Arm Motor |  reliability validity |  ability test |  activities daily living |  outcome measure
    KOL Index score: 8461

    ALTHOUGH phantom-limb pain is a frequent consequence of the amputation of an extremity, little is known about its origin1-4. On the basis of the demonstration of substantial plasticity of the somatosensory cortex after amputation5 or somatosensory deafferentation in adult monkeys6, it has been suggested that cortical reorganization could account for some non-painful phantom-limb phenomena in amputees and that cortical reorganization has an adaptive (that is, pain-preventing) ...

    Also Ranks for: Cortical Reorganization |  arm amputation |  limb pain |  perceptual correlate |  somatosensory cortex


    Edward Taub: Influence Statistics

    Sample of concepts for which Edward Taub is among the top experts in the world.
    Concept World rank
    fm change53±33 points #1
    standard oneonone therapy #1
    rehabilitation therapy goal #1
    total infarction volume #1
    3 hour day #1
    therapy profuse #1
    induced movement #1
    performance time and92 #1
    cns degenerative conditions #1
    neal miller #1
    nervous influential voice #1
    paper microcomputerbased devices #1
    difficulty participants #1
    concentrated repetitive #1
    95 tele #1
    children injured brain #1
    realworld spoken language #1
    range cvs wbmrsi #1
    laboratory motor activity #1
    thirtythree subacute stroke #1
    gains ecimt #1
    action unique aspects #1
    extremities types #1
    additional credibility #1
    learned nonuse formulation #1
    motor focused #1
    retention treatment responses #1
    impaired extremities #1
    svs wbmrsi #1
    95 telegaming #1
    therapy mri scans #1
    weeks cimt #1
    intensive twoweek #1
    constraintinduced movement cns #1
    types neurological injury #1
    tele gaming #1
    assistance balance #1
    subject laboratory #1
    mobility scale lemal #1
    expanded constraint #1
    basis cimt #1
    intact ulnar portion #1
    wmh overlap #1
    cimt depressive symptoms #1
    version pmal #1
    learned nonuse principles #1
    specific controlled form #1
    substantial cns damage #1
    object flipping #1
    wbmrsi metabolites #1

    Key People For Cortical Reorganization

    Top KOLs in the world
    Edward Taub
    cortical reorganization movement therapy chronic stroke
    Jon H Kaas
    somatosensory cortex owl monkeys superior colliculus
    Michael M Merzenich
    auditory cortex inferior colliculus critical period
    Herta Flor
    chronic pain phantom limb cortical reorganization
    Leonardo G Cohen
    motor cortex magnetic stimulation chronic stroke
    Thomas R Elbert
    appetitive aggression posttraumatic stress disorder narrative exposure therapy

    Edward Taub:Expert Impact

    Concepts for whichEdward Taubhas direct influence:Cortical reorganization,  Chronic stroke,  Movement therapy,  Phantom limb pain,  Induced movement,  Motor function,  Cerebral palsy,  Somatosensory cortex.

    Edward Taub:KOL impact

    Concepts related to the work of other authors for whichfor which Edward Taub has influence:Chronic stroke,  Upper limb,  Motor function,  Irritable bowel syndrome,  Cerebral palsy,  Somatosensory cortex,  Virtual reality.



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    Department of Psychology, University of Alabama at Birmingham (UAB), Birmingham, AL, USA. | University of Alabama Birmingham, Dept. of Psychology | Department of Psychology, University of Alabama at Birmingham, AL, Birmingham, USA. | Department of Ps