Joel V Weinstock: Influence Statistics

Joel V Weinstock

Joel V Weinstock

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA, USA | Tufts Medical Center, Boston, MA, USA | Division of ...

Joel V Weinstock: Expert Impact

Concepts for which Joel V Weinstock has direct influence: Murine schistosomiasis , Granuloma macrophages , Murine schistosomiasis mansoni , Granulomatous response , Granuloma cells , Schistosoma mansoni , Inflammatory bowel disease .

Joel V Weinstock: KOL impact

Concepts related to the work of other authors for which for which Joel V Weinstock has influence: Inflammatory bowel disease , Dendritic cells , Ulcerative colitis , Immune response , Gut microbiota , Hygiene hypothesis , Multiple sclerosis .

KOL Resume for Joel V Weinstock

Year
2022

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA, USA

2020

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA, United States

2019

Division of Gastroenterology/Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA 02111;

2018

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA, USA

2017

Tufts Medical Center Division of Gastroenterology Boston MA USA

2016

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA 02111;

2014

Division of Gastroenterology, Tufts Medical Center, Boston, MA 02111; and

2013

Division of Gastroenterology/Hepatology, Tufts Medical Center, Tufts University, Boston, MA 02111, USA

2012

Division of Gastroenterology, Tufts Medical Center, Boston, Massachusetts, USA

2010

Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center;

Department of Internal Medicine, Tufts–New England Medical Center, Boston, Mass

2009

Tufts New England Medical Center, Boston, Massachusetts

2008

Division of Gastroenterology, Tufts Medical Center, Boston, Massachusetts

Department of Veterans Affairs Medical Center, Iowa City, IA 52246;

2007

Division of Gastroenterology, Tufts New England Medical Center, Boston, MA, USA

Department of Internal Medicine, Tufts University, Boston, MA 02111

2006

1Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts-New England Medical Center, Boston, Massachusetts; 2Nutrient Requirements and Functions Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, Maryland; and 3Department of Internal Medicine, University of Iowa, Iowa City, Iowa

Division of Gastroenterology/Hepatology, Department of Medicine, Tufts University and New England Medical Center, Boston, MA 02111

Lecturer at Tufts–New England Medical Center, Boston, MA, USA

2005

Professor and Director of the Division of Gastroenterology/Hepatology at the University of Iowa, IA, USA

Department of Internal Medicine, Tufts University, Boston, Massachusetts

2004

James A Clifton Center for Digestive Diseases, Department of Internal Medicine, University of Iowa Roy J and Lucille Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA.

Department of Internal Medicine, Division of Gastroenterology-Hepatology, University of Iowa, Iowa City, IA 52242

University of Iowa Hospitals and Clinics, Division of Gastroenterology, Iowa City, IA, USA

2003

Department of Internal Medicine, University of Iowa, Iowa City, IA 52242; and

2002

Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa, 52242

Iowa City, Iowa, and Beltsville, Maryland

2001

Division of Gastroenterology-Hepatology, Department of Internal Medicine, University of Iowa, Iowa City, Iowa 52242, USA

2000

Department of Internal Medicine, University of lowa Hospitals and Clinics, lowa City, lowa, USA

1999

Department of Medicine, Division of Gastroenterology/Hepatology, University of Iowa Hospitals and Clinics, Room 4607 JCP, Iowa City, IA 52242-1009, USA

1998

Division of Gastroenterology‐Hepatology, Department of Medicine, University of Iowa, lowa City, Iowa 522423 USA

1997

From the Department of Pathology and Department of Internal Medicine, University of Iowa, Iowa City, IA; Department of Immunology, University Hospital Utrecht, Utrecht, The Netherlands; and Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI.

1996

Department of Internal Medicine, Veterans’ Affairs Medical Center, Iowa City, Iowa

1995

Department of Internal Medicine, University of Iowa, Iowa City 52242, USA.

Internal Medicine, College of Medicine, University of Iowa, Iowa City, IA, USA

1994

Division of Gastroenterology-Hepatology, Department of Internal Medicine, 4607JCP, University of Iowa College of Medicine, Iowa City, IA 52242, USA

1993

GI Division, Department of Medicine, University of Iowa, Iowa City, Iowa 52242

1992

Department of Pathology, University of Iowa, Iowa City, USA

Division of Gastroenterology and Hepatology, University of Iowa 4607 JCP, Iowa City, Iowa, 52242

1991

Iowa city, Iowa, USA

Prominent publications by Joel V Weinstock

KOL-Index: 13063 . BACKGROUND: The hygiene hypothesis suggests an inverse relationship between the incidence of parasitic infections and chronic inflammatory bowel diseases (IBD). We investigated the therapeutic potential of Schistosoma mansoni and Ancylostoma caninum soluble proteins on experimental colitis in mice. METHODS: Colitis was induced by intrarectal administration of 10 mg trinitrobenzene sulfonic ...
Known for Therapeutic Potential | Mice Colitis | Mansoni Proteins | Regulatory Cytokines
KOL-Index: 12784 . BACKGROUND AND AIMS: Total parenteral nutrition (TPN) is typically delivered through catheters inserted into the superior vena cava (SVC) via a subclavian or internal jugular vein approach. A peripherally-inserted central venous catheter (PICC), utilizing a cephalic or basilic venous approach, may provide a safe alternative to the standard catheter approach and, because non-physician ...
Known for Hospitalized Patients | Central Catheters | Parenteral Nutrition | Picc Lines
KOL-Index: 12271 . BACKGROUND & AIMS: Interleukin (IL)-10 is an anti-inflammatory and immune regulatory cytokine. IL-10-deficient mice (IL-10(-/-)) develop chronic inflammatory bowel disease (IBD), indicating that endogenous IL-10 is a central regulator of the mucosal immune response. Prostaglandins are lipid mediators that may be important mediators of intestinal inflammation. In this study we assessed the ...
Known for Il10 Mice | Nsaid Treatment | Intestinal Inflammation | Cytokine Production
KOL-Index: 11946 . Helminthic infections protect mice from colitis in murine models of inflammatory bowel disease and also may protect people. Helminths like Heligmosomoides polygyrus bakeri can induce regulatory T cells (Treg). Experiments explored whether H. polygyrus bakeri infection could protect mice from colitis through activation of colonic Treg and examined mechanisms of action. We showed that H. ...
Known for Polygyrus Bakeri | Mice Colitis | Intestinal Diseases | Regulatory Cells
KOL-Index: 11342 . We studied the effects of an anti-interleukin (IL)-5 monoclonal antibody (TRFK-5) or dexamethasone (DEX) to reverse already established airway hyperresponsiveness (AHR) and tissue eosinophilia in a Schistosoma mansoni antigen-sensitized and airway-challenged mouse model of chronic asthma. In this model at 4 d after antigen challenge there is dramatic bronchoalveolar lavage fluid (BAL) ...
Known for Airway Eosinophilia | Chronic Asthma | Murine Model | Antigen Challenge
KOL-Index: 11271 . Angiotensin I converting enzyme activity is detectable in serum and isolated liver granulomas of mice infected with Schistosoma mansoni. At the chronic phase of the infection (20 wk) the intensity of the granulomatous response spontaneously diminishes. Concomitantly, an increase in angiotensin I converting enzyme activity is observed. The objective of this investigation was to determine ...
Known for Converting Enzyme | Schistosoma Mansoni | Granuloma Macrophages | Infected Mice
KOL-Index: 11189 . Previous studies have shown that the pan CD28/cytotoxic T lymphocyte antigen (CTL)A-4 antagonist CTLA4 immunoglobulin (Ig) inhibits eosinophilic airway inflammation in Schistosoma mansoni-sensitized and airway-challenged mice. In the present study, the importance of CD28 as well as the individual roles of CD80 and CD86 were examined in this system using wild-type and CD28 knockout (KO) ...
Known for Cd80 Cd86 | Monoclonal Antigens | Airway Inflammation | Cd28 B7
KOL-Index: 11047 . Complete T-cell activation requires two distinct signals, one delivered via the T-cell receptor, and the second "co-stimulatory" signal through CD28/B7 ligation. Previous studies showed that the blockade of CD28/B7 ligation alters differentiation of Th1/Th2 lymphocyte subsets in vitro and in vivo. The present study was designed to determine the effect of a CD28/B7 antagonist (CTLA4Ig) on ...
Known for Murine Model | Airway Eosinophilia | Bal Fluid | Lung Lymphocytes
KOL-Index: 10724 . A novel costimulatory molecule expressed on activated T cells, inducible costimulator (ICOS), and its ligand, B7-related protein-1 (B7RP-1), were recently identified. ICOS costimulation leads to the induction of Th2 cytokines without augmentation of IL-2 production, suggesting a role for ICOS in Th2 cell differentiation and expansion. In the present study, a soluble form of murine ICOS, ...
Known for Allergic Airway Disease | Inducible Costimulator | Th2 Differentiation | Airway Inflammation
KOL-Index: 10181 . Less developed countries have a low incidence of immunological diseases like inflammatory bowel disease (IBD), perhaps prevented by the high prevalence of helminth infections in their populations. In the Rag IL-10(-/-) T cell transfer model of colitis, Heligmosomoides polygyrus, an intestinal helminth, prevents and reverses intestinal inflammation. This model of colitis was used to explore ...
Known for Heligmosomoides Polygyrus | Innate Immunity | Knockout Mice | Intestinal Inflammation
KOL-Index: 10001 . The intestinal epithelium forms an essential barrier between a host and its microbiota. Protozoa and helminths are members of the gut microbiota of mammals, including humans, yet the many ways that gut epithelial cells orchestrate responses to these eukaryotes remain unclear. Here we show that tuft cells, which are taste-chemosensory epithelial cells, accumulate during parasite ...
Known for Tuft Cells | Type 2 | Intestinal Diseases | Gut Microbiota
KOL-Index: 9938 . Immunological diseases such as inflammatory bowel disease (IBD) are infrequent in less developed countries, possibly because helminths provide protection by modulating host immunity. In IBD murine models, the helminth Heligmosomoides polygyrus bakeri prevents colitis. It was determined whether H. polygyrus bakeri mediated IBD protection by altering dendritic cell (DC) function. We used a ...
Known for Polygyrus Bakeri | Block Colitis | Dendritic Cells | Cell Responses
KOL-Index: 9872 . Murine schistosomiasis is a granulomatous disease associated with high serum and granuloma angiotensin I-converting enzyme (ACE) activity. SQ 14225, a specific competitive inhibitor of ACE, was administered to normal mice and mice infected with Schistosoma mansoni to determine whether this compound could inhibit granuloma ACE activity and modify the size of the granulomatous response to ...
Known for Granulomatous Response | Schistosoma Mansoni | Converting Enzyme | Normal Mice

Key People For Murine Schistosomiasis

Top KOLs in the world
#1
Dov L Boros
schistosoma mansoni granulomatous response murine schistosomiasis
#2
Allen W Cheever
schistosoma mansoni hepatic fibrosis inbred balb mice
#3
Edward J Pearce
schistosoma mansoni dendritic cells th2 responses
#4
Kenneth S Warren
schistosoma mansoni granuloma formation delayed hypersensitivity
#5
Alan Sher
schistosoma mansoni dendritic cells toxoplasma gondii
#6
Daniel G Colley
schistosoma mansoni human schistosomiasis immune responses

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA, USA | Tufts Medical Center, Boston, MA, USA | Division of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Cent