Robin J. Russell-Jones

Robin J. Russell-Jones

From The Skin Tumour Unit, St John's Institute Of Dermatology, St Thomas' Hospital; And The Department Of Public Health Sciences, Guy's, King's And St Thomas' School Of ...

Direct Impact

Concepts for which Robin J Russell-Jones has direct influence:

mycosis fungoides
sézary syndrome
extracorporeal photopheresis
cutaneous lymphoma
malignant melanoma
peripheral blood
livedoid vasculitis

External impact

Concepts related to the work of other authors for which Robin J Russell-Jones has influence:

mycosis fungoides
sézary syndrome
peripheral blood
high-dose etoposide
cutaneous t-cell lymphoma
erythrodermic actinic reticuloid
interferon alfa

Prominent publications by Robin J. Russell-Jones

KOL-Index: 77 The new WHO/EORTC classification for cutaneous lymphomas comprises mature T-cell and natural killer (NK)-cell neoplasms, mature B-cell neoplasms, and immature hematopoietic malignancies. It reflects the unique features of lymphoproliferative diseases of the skin, and at the same time it is as compatible as possible with the concepts underlying the WHO classification for nodal lymphomas and ...
Known for
Lymphoproliferative | Hematopoietic Malignancies | Molecular Aspects | Mature Neoplasms
KOL-Index: 60 AIMS: Aggressive epidermotropic cutaneous CD8(+) lymphoma is currently afforded provisional status in the WHO classification of lymphomas. An EORTC Workshop was convened to describe in detail the features of this putative neoplasm and evaluate its nosological status with respect to other cutaneous CD8(+) lymphomas. METHODS AND RESULTS: Sixty-one CD8(+) cases were analysed at the workshop; ...
Known for
Remainder | Lymphomas | Photographs | Distinct Pathological Features
KOL-Index: 42 We report 28 patients with advanced chronic graft-versus-host disease (cGVHD) treated with extracorporeal photopheresis (ECP). All had failed conventional immunosuppressive therapy. Of the patients, 27 had extensive cGVHD and 20 had more than 50% cutaneous surface area involvement. ECP was initiated approximately 2 years after onset of cGVHD and 3 years following allogeneic stem cell ...
Known for
Lung Function Tests | Allogeneic Stem Transplantation | Blood Counts | Extensive Cutaneous Cgvhd
KOL-Index: 35 Sézary syndrome (SS) is a rare form of erythrodermic cutaneous T-cell lymphoma with hematological involvement and a poor prognosis. At present little is known about the molecular pathogenesis of this malignancy. To address this issue, we analyzed 28 SS cases through the use of molecular cytogenetic techniques. Conventional cytogenetic analysis showed 12 of 28 cases with clonal chromosome ...
Known for
Revealed Chromosome | Fish Clonal | Syndrome Sézary | Gains Cis
KOL-Index: 34 Two conferences were sponsored by the International Society for Cutaneous Lymphomas (ISCL) to gain consensus on definitions and terminology for clinical use in erythrodermic cutaneous T-cell lymphoma (E-CTCL). Three subsets of E-CTCL were defined: Sézary syndrome ("leukemic phase" E-CTCL), erythrodermic mycosis fungoides (secondary E-CTCL that develops in patients with mycosis fungoides), ...
Known for
Sézary | Nodal Involvement | Conferences | Polymerase Chain Reaction Technique
KOL-Index: 33 Nine patients with tumour stage mycosis fungoides (MF) have been entered into a pilot study of T-cell depletion and autologous stem cell transplantation (SCT). Eight patients had detectable rearrangements of the T-cell receptor (TCR) gamma-gene demonstrated by polymerase chain reaction (PCR)/single-stranded conformation polymorphism (SSCP) in the peripheral blood. The median age was 47 years ...
Known for
7 Months | T-Cell Depletion | Sscp | Fungoides
KOL-Index: 30 BACKGROUND: Cutaneous lymphomas expressing a cytotoxic or natural killer (NK) cell phenotype represent a group of lymphoproliferative disorders for which there is currently much confusion and little consensus regarding the best nomenclature and classification. METHODS: This study analyzes 48 cases of primary cutaneous lymphoma expressing cytotoxic proteins and/or the NK cell marker, CD56. ...
Known for
Confusion | Nk Marker | Peripheral T-Cell Lymphoma | 3 Subcutaneous Panniculitis-Like T-Cell
KOL-Index: 30 We report 3 cases of mycosis fungoides (MF) with a CD56+ cytotoxic immunophenotype. Each patient presented with a different clinical phenotype: one exhibited limited poikilodermatous patches (skin stage T1); one, widespread hypopigmented lesions (skin stage T2); and one, poikiloderma with a single cutaneous tumor (skin stage T3). MF was confirmed both histologically and by the presence of a ...
Known for
Exhibited Tumor | Fungoides Cd56 | Immunophenotype Mycosis
KOL-Index: 27 There are few data on the molecular pathogenesis of cutaneous T cell lymphomas. A recent allelotyping study by our group identified frequent allelic loss on 9p, 10q, and 17p including losses on 9p21 in 16% of patients with mycosis fungoides and 46% with Sezary syndrome. The P15 and P16 genes are intricately linked on 9p21 and can be inactivated in melanoma and non-Hodgkin's lymphoma. We have ...
Known for
C613a | 17p | Cutaneous Lymphomas | Allelotyping

From the Skin Tumour Unit, St John's Institute of Dermatology, St Thomas' Hospital; and the Department of Public Health Sciences, Guy's, King's and St Thomas' School of Medicine, King's College, London, United Kingdom.

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