Kuang-Ming Hsiao

Kuang-Ming Hsiao

Institute Of Molecular Biology, National Chung Cheng University, 621, Chia-Yi, Taiwan Department Of Life Science, National Chung Cheng University, 168, University Road, ...

Direct Impact

Concepts for which Kuang-Ming Hsiao has direct influence:

myotonic dystrophy
myotonia congenita
calcium carbonate
growth regulation
cag repeats
indian muntjac
caenorhabditis elegans

External impact

Concepts related to the work of other authors for which Kuang-Ming Hsiao has influence:

laparoscopic cholecystectomy
limy bile
myotonic dystrophy
lysine residues
extended surface
bacterial meningitis
cystic duct

Prominent publications by Kuang-Ming Hsiao

KOL-Index: 110 BackgroundThe aim of this study is to compare efficacy and complications between fundus-down and conventional laparoscopic cholecystectomy (LC) in treating contracted gallbladders with gallstones.MethodsBetween January 1999 and May 2008, 64 patients with contracted gallbladders and gallstones were included in the study. Main outcome measures included conversion rate, complication rate, bile ...
Known for
Contracted | Technique Conventional | Backgroundthe Aim | Gallbladders
KOL-Index: 26 BACKGROUND: An increase in CAG trinucleotide repeat length in the androgen receptor (AR) gene has been linked to idiopathic azoospermia. METHODS: In order to test whether other (CAG/CTG)(n) loci are also affected, the (CAG/CTG)(n) frequency distribution at myotonic dystrophy type 1 (DM1), Machado-Joseph disease (MJD), dentatorubral-pallidoluysian atrophy (DRPLA) and spinocerebellar ataxia ...
Known for
Trinucleotide | Normal Alleles | Joseph Genes | Upper Tails
KOL-Index: 25 The low-density lipoprotein receptor-related protein 1 (LRP1) gene is associated with increased levels of plasma factor VIII (FVIII). We aimed to explore eight functional genetic LRP1 variants for their potential roles in regulating FVIII levels and acute ischemic stroke (AIS). This genetic association study enrolled 192 patients with AIS and 134 controls. There were no significant ...
Known for
Transfected Hepg2 Cells | 134 | 192 | Estimated Glomerular Filtration Rate
KOL-Index: 23 BACKGROUND/OBJECTIVES: Our aim was to investigate the calcium content of different gallstone compositions and the pathogenic mechanisms of calcium carbonate gallstones. METHODS: Between August 2001 and July 2007, gallstones from 481 patients, including 68 calcium carbonate gallstones, were analyzed for total calcium content. Gallbladder bile samples from 33 cases and six controls were ...
Known for
Compositions Gallstones | Intermittent Cystic | Bile Analyzed | Wall Inflammation
KOL-Index: 23 Irxl1/Mkx (Iroquois homeobox-like 1/Mohawk) encodes a member of the TALE subfamily of homeodomain proteins. It is expressed in multiple mesoderm-derived tissues and has recently been shown to regulate tendon differentiation during mouse embryonic development. Previously we showed that knockdown of Irxl1 in zebrafish caused a deficit in neural crest cells which consequently resulted in ...
Known for
Luciferase Reporter Assays | Irxl1 Knockdown Morphants | Neural Crest Cells | Direct Binding
KOL-Index: 16 Iroquois homeobox-like 1 (irxl1) is a novel member of the TALE superfamily of homeobox genes that is most closely related to the Iroquois class. We have identified the zebrafish irxl1 gene and characterized its structure. The protein contains a homeodomain that shares 100% sequence identity with other vertebrate orthologs. During embryogenesis, irxl1 is expressed from 18 hours ...
Known for
Neural Crest Cells | 18 Hours Postfertilization | Irxl1 Brain | Homeobox
KOL-Index: 16 Acute bacterial meningitis causes high morbidity and mortality; the associated clinical symptoms often are insensitive or non-specific; and the pathogenic bacteria are geographically diverse. Clinical diagnosis requires a rapid and accurate methodology. This study aimed to develop a new multiplex polymerase chain reaction (mPCR) assay to detect simultaneously six major bacteria that cause ...
Known for
Major Bacterial | Reaction Mpcr | Cfu Coli | Pathogens Acute
KOL-Index: 15 A minilibrary was constructed from DOP-PCR products using microdissected Y-chromosomes of Indian muntjac as DNA templates. Two microclones designated as IM-Y4-52 and IM-Y5-7 were obtained from negative screening of all three cervid satellite DNAs (satellites I, II, and IV). These two microclones were 295 and 382 bp in size, respectively, and shared ∼70% sequence homology. Southern blot ...
Known for
Minilibrary | Muntjacs | Dna Templates | Deleted Monomers
KOL-Index: 15 We present the clinical manifestations, brain magnetic resonance images (MRI), and genetic analysis of a family with 2 siblings with congenital myotonic dystrophy type 1 (DM1) and 4 patients with classic DM1. These 2 patients with congenital DM1 had severe mental retardation and a characteristic feature of hyperintensity of white matter at the posterior-superior trigone (HWMPST), in addition ...
Known for
Resonance Image | Diffuse Impairment | Congenital Classic | Characteristic Finding
KOL-Index: 15 The most frequent trinucleotide repeat found in human disorders is the CAG sequence. Expansion of CAG repeats is mostly found in coding regions and is thought to cause diseases through a protein mechanism. Recently, expanded CAG repeats were shown to induce toxicity at the RNA level in Drosophila and C. elegans. These findings raise the possibility that CAG repeats may trigger RNA-mediated ...
Known for
Histochemistry | Coding Regions | 0 23 Cag Repeats | Rna Level

Institute of Molecular Biology, National Chung Cheng University, 621, Chia-Yi, Taiwan Department of Life Science, National Chung Cheng University, 168, University Road, Min-Hsiung, 62102, Chia-Yi, Taiwan, ROC

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