• Disease
  • Bifurcation
  • Bifurcation Lesions
  • Shaoliang Chen

    Prominent publications by ShaoLiang Chen

    KOL Index score: 10559

    BACKGROUND: There is a paucity of data from large cohort studies examining the prognostic significance of obstructive sleep apnea (OSA) in patients with coronary artery disease. We hypothesized that OSA predicts subsequent major adverse cardiac and cerebrovascular events (MACCEs) in patients undergoing percutaneous coronary intervention.

    METHODS AND RESULTS: The Sleep and Stent Study was a prospective, multicenter registry of patients successfully treated with percutaneous coronary ...

    Also Ranks for: Percutaneous Coronary |  cardiovascular events |  osa patients |  obstructive sleep apnea |  sleep study
    KOL Index score: 6151

    AIM: To investigate the remodeling of mesenteric artery and the expression of TGF-beta1, c-Jun in mesenteric artery and effects of imidapril and irbesartan on the remodeling in spontaneously hypertensive rats (SHR).

    METHODS: Thirty SHR (male/female, 21/9), aged 13 wk, were randomly divided into 3 groups (7 male rats and 3 female rats each group): SHR group, imidapril group (imidapril 3 mg/kg.d was given in drinking water for 14 wk), and irbesartan group (irbesartan 50 mg/kg.d was given ...

    Also Ranks for: Shr Wky |  hypertensive rats |  transforming growth |  beta1 angiotensin |  converting enzyme
    KOL Index score: 5620

    AIMS: There is uncertainty on which stenting approach confers the best long-term outlook for unprotected left main (ULM) bifurcation disease.

    METHODS AND RESULTS: This is a non-randomized, retrospective study including all consecutive patients with 50% stenosis of the left main involving at least 1 of the arteries stemming from the left main treated with drug-eluting stents (DES) in 9 European centers between 2002 and 2004. Patients were divided into two groups: those treated with ...

    Also Ranks for: Coronary Artery |  provisional stenting |  stent strategy |  target lesion revascularization |  cardiovascular death
    KOL Index score: 5299

    (99m)Technetium-labeled diethylenetriamine pentaacetic acid-polyethylene glycol-folate (DTPA-PEG-folate) was synthesized and tested as a radiopharmaceutical agent, which targeted the lymphatic system with metastatic tumor. Folic acid was reacted with H2N-PEG-NH2 to yield H2N-PEG-folate. After purification by anion-exchange chromatography, the product was reacted with cyclic DTPA. By removal of unreacted DTPA by size-exclusion chromatography, DTPA-PEG-Folate was obtained. ...

    Also Ranks for: Folic Acid |  biological evaluation |  polyethylene glycols |  subcutaneous injection |  cell uptake
    KOL Index score: 4027

    An increasing number of studies have been devoted to studying the respiratory toxicity of carbon nanomaterials, but little information is known, thus far, on the biodistribution of these nanomaterials after inhalation or intratracheal instillation. We synthesized and labeled a polyhydroxylated derivative of fullerene C60(OH)x (x=22,24) with 99mTc. With single photon emission computed tomography imaging and 〈gamma〉-ray counting techniques, the biodistribution of 99mTc-C60(OH)x in ...

    Also Ranks for: Intratracheal Instillation |  carbon nanomaterials |  dawley rats |  fast clearance |  highest retention
    KOL Index score: 2061

    Management of empyema with bronchopleural fistula remains a challenge. A 38-year-old man who had bullous emphysema was hospitalized on account of a right-sided necrotizing pneumonia complicated by empyema that mandated a tube drainage. Persistent air leak from the chest tube was noted, and chest computed tomography confirmed an empyema cavity with a suspicious bronchopleural fistula. This complex condition was successfully treated using fibrin glue with buttressed bovine pericardium to ...

    Also Ranks for: Bronchopleural Fistula |  pleural diseases |  muscle flap |  air leak |  necrotizing pneumonia
    KOL Index score: 1989

    BACKGROUND: Current guidelines recommend administering dual antiplatelet therapy (DAPT) for 12 months to patients with acute coronary syndromes (ACS) and without contraindications after drug-eluting stent (DES) implantation. A recent study reported that 3 months of DAPT followed by ticagrelor monotherapy is effective and safe in ACS patients undergoing DES implantation compared with the standard duration of DAPT. However, it is unclear whether antiplatelet monotherapy with ticagrelor ...

    Also Ranks for: Pci Patients |  acute coronary |  ivus guided |  macce 1 |  major adverse
    KOL Index score: 1051

    BACKGROUND: The risk/benefit tradeoff of dual antiplatelet therapy after percutaneous coronary intervention may vary in East Asian patients as compared with their non-East Asian counterparts.

    METHODS: The double-blind, placebo-controlled, randomized TWILIGHT trial (Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention) enrolled patients undergoing high-risk percutaneous coronary intervention. After 3 months of treatment with ticagrelor plus aspirin, ...

    Also Ranks for: Undergoing Percutaneous |  coronary intervention |  dual antiplatelet therapy |  events compared
    KOL Index score: 775

    The vessel wall is an intricate structure composed of three layers: the intima (consisting of endothelial cells), media (consisting of smooth muscle cells and elastic fibers), and externa (consisting of the extracellular matrix scaffold). The homeostasis of the vasculature depends on the consistent function of each layer. In the vascular system, potassium channels are well known to regulate vascular function. The interactions between vascular conditions and membrane potential are ...

    Also Ranks for: Potassium Channels


    ShaoLiang Chen: Influence Statistics

    Sample of concepts for which ShaoLiang Chen is among the top experts in the world.
    Concept World rank
    macces osa #14
    polyhydroxylated derivative #23
    eluting microporous #24
    microporous stent #25
    c60ohx #68

    Key People For Bifurcation Lesions

    Top KOLs in the world
    Antonio Colombo
    aortic valve coronary artery stent implantation
    Patrick W J C Serruys
    coronary artery myocardial infarction balloon angioplasty
    Yves Louvard
    bifurcation lesions coronary angiography myocardial infarction
    Martin B Leon
    aortic valve intravascular ultrasound coronary artery
    Manuel Pan
    bifurcation lesions mitral regurgitation coronary intervention
    Thierry Lefèvre
    aortic valve bifurcation lesions coronary artery

    ShaoLiang Chen:Expert Impact

    Concepts for whichShaoLiang Chenhas direct influence:Bifurcation lesions,  Coronary intervention,  Bronchopleural fistula,  Percutaneous coronary,  Acs patients,  Intravascular ultrasound,  Osa patients,  Patients osa.

    ShaoLiang Chen:KOL impact

    Concepts related to the work of other authors for whichfor which ShaoLiang Chen has influence:Obstructive sleep apnea,  Coronary artery disease,  Osa patients,  Cardiovascular outcomes,  Sleep apnoea,  Cpap adherence,  Carbon nanomaterials.



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    Nanjing Medical University - Department of Cardiology | Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China. Electronic address: chmengx@126.com. | Department of Cardiology, Nanjing First