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Annette C Douglas‐Akinwande: Influence Statistics

PURPOSE: To evaluate single-voxel proton magnetic resonance (MR) spectroscopy in detection of abnormality of the upper motor neuron in patients with motor neuron diseases.

MATERIALS AND METHODS: In 43 of 50 patients with motor neuron disease and 14 of 14 control subjects, matching sets of MR spectra were obtained in the left and right motor cortex. The ratio of N-acetylaspartate (NAA) to creatine (Cr) was derived from peak area measurements. Mean ratios were calculated for control ...

OBJECTIVE: The purpose of this study was to determine the accuracy of IV contrast-enhanced MDCT and MRI for evaluation of the severity and cause of neural foraminal stenosis in patients with cervical radiculopathy.

SUBJECTS AND METHODS: Eighteen patients with cervical radiculopathy prospectively underwent contrast-enhanced MDCT and MRI. Contrast-enhanced MDCT scans were acquired at 1-mm thickness and reconstructed in oblique axial (parallel to disk) and sagittal (perpendicular to neural ...

BACKGROUND: Although previous reports purport that the unique magnetic resonance imaging (MRI) features of Lhermitte-Duclos disease (LDD) obviates the need for biopsy, medulloblastoma can have an indistinguishable imaging appearance.

CASE DESCRIPTION: We present a patient who suffered from a medulloblastoma that demonstrated no enhancement and had imaging characteristics that were indistinguishable from LDD. This atypical imaging appearance, which could potentially be confused with LDD, ...

Evaluating the spine in patients with metal orthopedic hardware is challenging. Although the effectiveness of conventional computed tomography (CT) can be limited by severe beam-hardening artifacts, the evolution of multichannel CT in recent years has made available new techniques that can help minimize these artifacts. Multichannel CT allows faster scanning times, resulting in reduced motion artifacts; thinner sections, with which it is possible to create a scanned volume of isotropic ...

RATIONALE AND OBJECTIVES: The aim of this study was to quantify, using diffusion-weighted magnetic resonance imaging, the microscopic rate of water diffusion in pure germinoma and to determine whether or not the apparent diffusion coefficient (ADC) values correlated with the different histologic components.

MATERIALS AND METHODS: A retrospective analysis of echoplanar diffusion-weighted magnetic resonance images was conducted on 10 patients with 11 germinoma lesions. All images were ...

Astroblastoma is a rare primary glial tumor of children and young adults, typically located in the cerebral hemispheres and presenting as a well-circumscribed, nodular, often cystic enhancing mass. The existence of astroblastoma as a distinct clinicopathologic entity has long been debated but is recognized in the 2007 WHO classification of CNS tumors. The grading of these tumors remains unsettled. Currently, no grade has been established and there are no clearly defined diagnostic ...

Phosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists ...

BACKGROUND: When an epidural catheter is present, new motor deficits will often be attributed to a local anesthetic effect, potentially delaying imaging studies, or to an epidural hematoma, ignoring other mechanisms of spinal cord injury.

METHODS: A 69-yr-old female patient undergoing thoracotomy received a preoperative thoracic epidural for postoperative analgesia.

RESULTS: Intraoperatively, there was bleeding near the costovertebral junction. Hemorrhage was controlled with cellulose ...

We present a case of rotational vertebrobasilar insufficiency diagnosed and followed by computed tomography angiography. Diagnosis of this entity provides a unique challenge in that the patient must be positioned properly to avoid a false-negative result without causing ischemic brain injury. The evaluation of rotational vertebrobasilar insufficiency with computed tomography angiography has never been described in the literature to the best of our knowledge. We highlight the advantages ...

We describe a case of a 14-year-old boy who developed a cerebellar and brainstem glioblastoma 5 years after treatment for a medulloblastoma. The patient first presented in 2003 with 9 months of vomiting and a 9-kg weight loss. A head MRI showed a heterogeneously enhancing posterior fossa mass with hydrocephalus. Gross total resection was performed and the tumor was consistent with a classic medulloblastoma. Postoperative chemotherapy and craniospinal radiation was administered. The ...

We report an unusual case of primary intracranial germinoma involving the sphenoid bone and sinus. To the best of our knowledge, paranasal sinus and bone invasion of primary intracranial germinoma has not been previously reported. Recognition of this rare form of presentation by imaging is important because early radiation and chemotherapy can result in a cure of this neoplasm.

A 41-year-old woman with a 12-year history of von Hippel-Lindau disease presented with progressive quadriparesis and difficulty swallowing. MRI revealed a well-circumscribed, partially cystic cerebellar neoplasm, consistent with hemangioblastoma. The tumor was resected and the diagnosis of hemangioblastoma confirmed. Embedded within the hemangioblastoma was a small focus of metastatic renal cell carcinoma (RCC). RCC metastatic to a CNS hemangioblastoma is the second most common type of ...