PAUL A GREENBERG

BACKGROUND: Parkinson's disease (PD) disrupts temporal processing, but the neuronal sources of deficits and their response to dopamine (DA) therapy are not understood. Though the striatum and DA transmission are thought to be essential for timekeeping, potential working memory (WM) and executive problems could also disrupt timing.

METHODOLOGY/FINDINGS: The present study addressed these issues by testing controls and PD volunteers 'on' and 'off' DA therapy as they underwent fMRI while ...

SUBUNGUAL splinter hemorrhages are generally considered to be part of the clinical picture of bacterial endocarditis, but the fact that they are also seen in a wide variety of other conditions has been appreciated only recently.The association of splinter hemorrhages with bacterial endocarditis dates to 1920, when Sir Thomas Horder described "a minute petechia in the form of a vivid linear splash of red at the side of the bed of a finger nail" in a patient with bacterial endocarditis.1 ...

A high incidence of unsuspected pathology has been demonstrated by the routine use of intravenous pyelography in preparing patients for elective major gynecologic operations. In this series, in addition to disclosing a large number of unsuspected instances of genitourinary tract abnormalities, the screening technique was more productive in terms of disclosing unsuspected pathologic conditions, exclusive of urinary tract abnormality, than the coincidentally performed chest radiographs.It ...