![]() | H Richard TylerProfessor of Neurology, Harvard Medical School. Director, Neurological Services, Brigham and Women’s Hospital, Boston, Massachusetts | Section of Neurology, Department of ... |
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H Richard Tyler:Expert Impact
Concepts for whichH Richard Tylerhas direct influence:Lumbar puncture,Paraneoplastic syndromes,Neurological complications,Ganglioside therapy,Human botulism,Amyotrophic lateral sclerosis,Lateral sclerosis,Amyotrophic lateral.
H Richard Tyler:KOL impact
Concepts related to the work of other authors for whichfor which H Richard Tyler has influence:Measles virus,Unilateral asterixis,Botulinum toxin,Hepatic encephalopathy,Paraneoplastic syndromes,Infant botulism,Amyotrophic lateral sclerosis.
KOL Resume for H Richard Tyler
Year | |
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1984 | Professor of Neurology, Harvard Medical School. Director, Neurological Services, Brigham and Women’s Hospital, Boston, Massachusetts Section of Neurology, Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA |
1974 | Peter Bent Brigham Hospital Department of Neurology Harvard Medical School Boston, Massachusetts 02115 |
1965 | Peter Bent Brigham Hospital, Boston, Massachusetts U.S.A. |
1957 | * Fellow of the National Foundation for Infantile Paralysis From the Department of Neurology, Harvard Medical School and Peter Bent Brigham Hospital, Boston, Massachusetts From the Subdepartment of Neurology and Department of Pediatrics, Johns Hopkins Hospital |
Concept | World rank |
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neurologic manifestations tremor | #1 |
term botulism | #6 |
rubeola measles | #7 |
botulus | #14 |
publication dyskinesias humans | #17 |
tremor dyskinesias | #24 |
manifestations tremor | #44 |
measles humans | #53 |
ganglioside therapy | #63 |
leakage csf | #82 |
rubeola | #86 |
botulinus | #89 |
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Prominent publications by H Richard Tyler
Trials of Ganglioside Therapy for Amyotrophic Lateral Sclerosis and Diabetic Neuropathy
[ PUBLICATION ]
In a number of experimental situations exogenously administered gangliosides have been demonstrated to speed recovery from axonotmesis. First demonstrated for the pre-and postganglionic sympathetic fibers of the cat nictitating membrane,1 it has now been demonstrated also for the rat sciatic nerve2 and rat tail nerve.3 The mechanism of action seems to be stimulation of the sprouting process.3,4 Hence, gangliosides would be expected to be beneficial in conditions such as traumatic nerve ...
Known for Ganglioside Therapy | Amyotrophic Lateral Sclerosis | Topic Diabetes Mellitus | Diabetic Neuropathy | 1 Diabetes |
Surgical treatment of post-lumbar puncture dural CSF leak causing chronic headache. Case report.
[ PUBLICATION ]
A 58-year-old woman experienced incapacitating headache and occipital paresthesiae for 5 years after lumbar myelography. Conservative methods of treatment failed. Successive investigations for a suspected cerebrospinal fluid (CSF) leak were unrevealing. Leakage of CSF from the subarachnoid space into the epidural space in the lumbar region was finally confirmed when oil-soluble contrast material (Pantopaque), injected into the cervical subarachnoid space, was revealed by a specific ...
Known for Lumbar Puncture | Dural Defect | Cerebrospinal Fluid | Leakage Csf | Headache Humans |
Although the sudden flap, or lapse of posture, known as "asterixis" has become familiar as a distinct entity, its classic descriptions have always encompassed more than one form of abnormality.In 1949 Adams and Foley1 described a "fixed tremor state" in certain patients with liver disease.Two years later the same authors referred to the phenomena as a "motor disturbance—so unique that it merits a more complete description" (Adams and Foley, 1951).2 They then suggested that two ...
Known for Liver Disease | Movement Disorders | Diagnosis Differential | Dyskinesias Electromyography | Adams Foley |
A recent epidemic of botulism afforded us the opportunity of recording some physiological observations, made for the first time, on the effect of the toxin in man. Previous knowledge of the physiological action of the botulinus toxin was based primarily on laboratory experimentation in cold- and warm-blooded animals. The marked species differences in response to toxin suggested the importance of confirming these laboratory observations in man.In 1874 Pürkhauser1 first suggested that in ...
Known for Human Botulism | Repetitive Stimulation | Physiological Action | Botulinus Toxin |
Known for Paraneoplastic Syndromes | Nervous Diseases | Neurons Muscular |
Known for Myasthenia Gravis | Cord Paralysis | Humans Laryngeal | Nerve Vocal |
Botulism is an extremely rare, yet deadly, form of food poisoning. Because of the reputation of the botulinus toxin as the "most poisonous poison"1 known to man, it has long captivated the interest of laymen, scientists, and physicians.Although cases of "sausage poisoning" were described as early as 1735, the first significant outbreak occurred in 1793 in Würtemberg. The term botulism (from the latin word Botulus, which means sausage) was applied to this syndrome. By 1802 the condition ...