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    • Troels Staehelin Staehelin‐jensen
    • Troels Staehelin Staehelin‐Jensen

      Troels Staehelin Staehelin‐Jensen

      Department of Neurology, Aarhus University Hospital, Aarhus, Denmark | Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. | Danish Pain Research Center, ...



      KOL Resume for Troels Staehelin Staehelin‐Jensen


      Department of Neurology, Aarhus University Hospital, Aarhus, Denmark


      Department of Neurology, Aarhus University Hospital, Denmark


      Department of Clinical Medicine, Health, Aarhus University, Aarhus


      Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, University of Aarhus, Aarhus C, Denmark


      Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Århus, Denmark.


      Danish Pain Centre, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

      IDNC and DPRC Department of Neurology, Aarhus University Hospital, Aarhus, Denmark


      Department of Neurology, Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark,

      Aarhus University Hospital Danish Pain Research Centre Aarhus Denmark


      Danish Pain Research Center, Department of Neurology, Aarhus University Hospital, Denmark.

      Aarhus University Hospital Department of Neurology Aarhus Denmark


      From the Danish Pain Research Center and Department of Neurology, Aarhus University Hospital, Aarhus, Denmark (A.J.T., T.S.J.); Department of Neurology, Division of Neurological Pain Research and Therapy, University Hospital of Schleswig-Holstein, Kiel, Germany (J.G.); Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark (N.B.F.); and Department of Orthopedic Surgery, Odense University Hospital, Odense, Denmark (A.P.H.).

      Department of Neurology Danish Pain Research Centre Aarhus University Hospital Denmark


      Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark, Center for Functionally Integrative Neuroscience (CFIN), MindLab, Aarhus University Hospital, Aarhus, Denmark, Department of Neurology, Aarhus University Hospital, Aarhus, Denmark

      Department of Neurology, and


      Aarhus University Hospital Center for Functionally Integrative Neuroscience (CFIN), MindLab Denmark


      Department of Neurology and Danish Pain Research Center, Aarhus University Hospital, Norrebrogade 44, Building 1A, DK‐8000 Aarhus C, Denmark

      Danish Pain Research Center, Aarhus University Hospital, Aarhus C



      Troels Staehelin Staehelin‐Jensen: Influence Statistics

      Sample of concepts for which Troels Staehelin Staehelin‐Jensen is among the top experts in the world.
      Concept World rank
      prevalence large fibre #1
      ipa dms #1
      aetiological condition #1
      aversive behavior peap #1
      12 imipramine #1
      etiology painful polyneuropathy #1
      thymectomised patients #1
      neuropathy scales questionnaires #1
      lidocaine 20 #1
      allodynia winduplike pain #1
      20 nmol bradykinin #1
      positive emotional feelings #1
      neuropathic pain impact #1
      studies young age #1
      pain operative #1
      suprathreshold stimuli hpt #1
      masseter muscle combination #1
      controls whiplash trauma #1
      thymoma favourable prognosis #1
      ketamine allodynia #1
      somatosensory deficits assessment #1
      surgery sensory abnormalities #1
      mprotein tissue structures #1
      pretreatment tramadol #1
      head antidepressants #1
      stroke onset predictor #1
      experimental pain levels #1
      diagnostic accuracy dsp #1
      nervous lesion #1
      allodynia polyneuropathy #1
      saline injection btxa #1
      pain‐relieving effectiveness #1
      sensory reduction mammaplasty #1
      method muscle sensitivity #1
      npv ncs #1
      npdpn 51 #1
      qst scs #1
      dopamine mediated alteration #1
      pain lamotrigine #1
      level spinal injury #1
      postoperative phantom #1
      sweden astra #1
      phenotypes genetic study #1
      areas psychophysical study #1
      electrical stimulation pa #1
      blockade aδfibers #1
      placebos thoracotomy #1
      axonal swelling ratios #1
      infusions nacl #1
      training corticomotor excitability #1


      Prominent publications by Troels Staehelin Staehelin‐Jensen

      KOL-Index: 18302

      The significance of preamputation pain for the development of postamputation stump and phantom pain has been discussed over the years and is still a matter of dispute. It has been argued that preamputation pain increases the risk of phantom pain and that phantom pain is a revivification of pain experienced before the amputation. The purpose of this prospective study was to clarify the relation between preamputation pain and phantom pain. Fifty-six patients scheduled for amputation of a ...

      Known for Phantom Pain | Postamputation Stump | Amputation Preamputation | Lower Limb | Visual Analogue Scale
      KOL-Index: 16201

      In rats stereotaxically implanted with microinjection cannula in either the periaqueductal gray matter (PAG) or the medial/paramedial medullary reticular formation (MRF), microinjection of morphine, sufentanil, D-Ala2-D-Leu5-enkephalin (DADL) or D-Ser2-Thr6-leucine enkephalin (DSTLE) produced dose-dependent elevations in the response latency on tail-flick and hot plate tests. These effects were reversed by naloxone administered by microinjection into the same intracerebral site. Both mu ...

      Known for Delta Opioid | Antinociceptive Action | Leucine Enkephalin | Pag Mrf | Microinjection Morphine
      KOL-Index: 15610

      In a prospective study 58 patients undergoing limb amputation were interviewed the day before operation about their pre-amputation limb pain and 8 days, 6 months and 2 years after limb loss about their stump and phantom limb pain. All but one patient had experienced pain in the limb prior to amputation. Pre-amputation limb pain lasted less than 1 month in 25% of patients and more than 1 month in the remaining 75% of patients. At the first examination the day before amputation 29% had no ...

      Known for Limb Pain | Patients Amputation | 6 Months | Clinical Characteristics | 2 Years
      KOL-Index: 15264

      BACKGROUND: Epidural analgesia before limb amputation is commonly used to reduce postamputation pain. But there have been no controlled studies with large numbers of patients to prove such a pre-emptive effect. We investigated whether postamputation stump and phantom pain in the first year is reduced by preoperative epidural blockade with bupivacaine and morphine.

      METHODS: In a randomised, double-blind trial, 60 patients scheduled for lower-limb amputation were randomly assigned epidural ...

      Known for Phantom Pain | Limb Amputation | Epidural Bupivacaine | 1 Week | Intensity Stump
      KOL-Index: 15040

      BACKGROUND: New drug treatments, clinical trials, and standards of quality for assessment of evidence justify an update of evidence-based recommendations for the pharmacological treatment of neuropathic pain. Using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE), we revised the Special Interest Group on Neuropathic Pain (NeuPSIG) recommendations for the pharmacotherapy of neuropathic pain based on the results of a systematic review and ...

      Known for Neuropathic Pain | International Association | Tricyclic Antidepressants | Opioid Antidepressive Agents | Lidocaine Patches
      KOL-Index: 14624

      STUDY DESIGN: A 6-month prospective study of neck mobility in patients with acute whiplash injury and a control group with acute ankle distortion was conducted.

      OBJECTIVES: To assess active neck mobility after acute whiplash and ankle distortion injuries, and to relate neck mobility to headache, neck pain, and speed of car at the time of collision.

      SUMMARY OF BACKGROUND DATA: A major problem after whiplash injury is restriction of neck mobility immediately subsequent to trauma. It is, ...

      Known for Neck Pain | Whiplash Injury | Cervical Range | Background Data | 1 Week
      KOL-Index: 14074

      BACKGROUND: In chronic pain, increased activity from intact or damaged peripheral nerve endings results in an enhanced response in central pain transmission systems, a mechanism known as central sensitization. Central sensitization can also be invoked in human experimental models. Therefore, these models may be useful to characterize novel analgesics in humans. The anticonvulsant gabapentin has demonstrated efficacy in patients with neuropathic pain, but its mode of action remains ...

      Known for Central Sensitization | Oral Gabapentin | Neuropathic Pain | Intradermal Capsaicin | Placebo Area
      KOL-Index: 13789

      The incidence and clinical picture of non-painful and painful phantom limb sensations as well as stump pain was studied in 58 patients 8 days and 6 months after limb amputation. The incidence of non-painful phantom limb, phantom pain and stump pain 8 days after surgery was 84, 72 and 57%, respectively. Six months after amputation the corresponding figures were 90, 67 and 22%, respectively. Kinaesthetic sensations (feeling of length, volume or other spatial sensation of the affected limb) ...

      Known for Phantom Pain | Limb Amputation | 6 Months | Followup Period | 58 Patients
      KOL-Index: 13678

      BACKGROUND: The recommended dose for intravenous (IV) paracetamol injection in adults is 1g, however pharmacokinetic and pharmacodynamic findings suggest that a better analgesia could be obtained with a 2 g starting dose.

      METHODS: A single-centre, randomised, double-blind, placebo-controlled, 3-parallel group study was performed to demonstrate the analgesic efficacy and safety of IV paracetamol 2 g. Following third molar surgery, patients reporting moderate to severe pain received a ...

      Known for Molar Surgery | Analgesic Efficacy | Intravenous Paracetamol | Starting Dose | Postoperative Pain
      KOL-Index: 12988

      The microinjection through stereotaxically implanted guide cannulae of morphine (5 micrograms/0.5 microliter) into the periaqueductal gray, the n. raphe magnus or the n. reticulogigantocellularis results in a significant elevation in the latency of a thermally evoked, spinally mediated reflex (tail-flick) and a supraspinally organized response (hot-plate). Spinal serotonin, noradrenalin, opiate and dopamine receptors were antagonized by the injection through chronically implanted ...

      Known for Periaqueductal Gray | Raphe Magnus | Methysergide Phentolamine | Intrathecal Antagonists | Microinjection Morphine
      KOL-Index: 12514

      Microinjection of morphine (5 micrograms) through stereotaxically implanted microinjection cannulas into the periaqueductal gray (104 sites), medial (n. raphe magnus; 26 sites) and paramedial (n. reticulogigantocellularis; 49 sites) medulla resulted in an increase in the latency of supraspinally (hot-plate) and spinally (tail-flick)-mediated responses evoked by thermal stimuli. This effect of intracerebral morphine on both hot-plate and tail-flick was dose-dependent, and reversed by ...

      Known for Morphine Periaqueductal Gray | Antinociceptive Action | Raphe Magnus | Inbred Strains Receptors | Thermal Stimuli
      KOL-Index: 12475

      In the present study, we assessed the muscle pain and possible development of muscular hyperalgesia to mechanical stimuli after two subsequent intramuscular infusions of serotonin (5-HT) and bradykinin (BKN). The pain intensity after the infusions was continuously scored on a visual analogue scale (VAS). The subjects drew the distribution of the pain areas on a map. Pressure pain thresholds (PPTs) and suprapressure pain thresholds (SPPTs) stimulations as 150% of the pre-infusion PPTs ...

      Known for Muscle Pain | Serotonin Bradykinin | Muscular Hyperalgesia | Isotonic Saline | Mechanical Stimuli
      KOL-Index: 12269

      Spinal cord injury (SCI) frequently results in neuropathic pain. However, the pathophysiology underlying this pain is unclear. In this study, we compared clinical examination, quantitative sensory testing (QST) and somatosensory evoked potentials (SEPs) in SCI patients with and without pain below spinal lesion level, with a control group of 20 subjects without injury. All patients had a traumatic SCI with a lesion above T10; 20 patients presented with spontaneous central neuropathic pain ...

      Known for Injury Patients | Central Pain | Sensory Function | Lesion Level | Spinal Cord
      KOL-Index: 12163

      Neuropathic pain is due to lesion or dysfunction of the peripheral or central nervous system. Tricyclic antidepressants and anticonvulsants have long been the mainstay of treatment of this type of pain. Tricyclic antidepressants may relieve neuropathic pain by their unique ability to inhibit presynaptic reuptake of the biogenic amines serotonin and noradrenaline, but other mechanisms such as N-methyl-D-aspartate receptor and ion channel blockade probably also play a role in their ...

      Known for Neuropathic Pain | Tricyclic Antidepressants | Serotonin Reuptake | Drug Class | Uptake Inhibitors
      KOL-Index: 12011

      The aim of the present study was to test (1) whether muscle pain is influenced by temporal and spatial summation, and (2) whether sequential noxious muscle stimuli applied at hourly interstimulus-intervals could produce an increased sensation of pain due to central hyperexcitability. In the study eleven healthy men were exposed to computer-controlled intramuscular infusion of saline (5%) given over 20 s in m. tibialis anterior (m. TA). The intensities of local and referred pain were ...

      Known for Hypertonic Saline | Muscle Pain | Local Referred | Temporal Spatial Summation | Infusion Site

      Key People For Neuropathic Pain

      Top KOLs in the world
      Troels Staehelin Staehelin‐Jensen
      neuropathic pain whiplash injury spinal cord
      Clifford J Woolf
      spinal cord dorsal horn neuropathic pain
      Ralf Baron
      neuropathic pain fabry disease postherpetic neuralgia
      Nadine ATTAL
      neuropathic pain botulinum toxin analgesic effects
      Gary J Bennett
      neuropathic pain spinal cord sciatic nerve
      Robert H Dworkin
      chronic pain herpes zoster postherpetic neuralgia

      Troels Staehelin Staehelin‐Jensen:Expert Impact

      Concepts for whichTroels Staehelin Staehelin‐Jensenhas direct influence:Neuropathic pain,  Chronic pain,  Phantom pain,  Whiplash injury,  Peripheral neuropathic pain,  Painful polyneuropathy,  Neck pain,  Spinal cord.

      Troels Staehelin Staehelin‐Jensen:KOL impact

      Concepts related to the work of other authors for whichfor which Troels Staehelin Staehelin‐Jensen has influence:Neuropathic pain,  Spinal cord,  Trigeminal neuralgia,  Multiple sclerosis,  Nerve injury,  Phantom limb,  Central sensitization.



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      Department of Neurology, Aarhus University Hospital, Aarhus, Denmark | Department of Clinical Medicine, Aarhus University, Aarhus, Denmark. | Danish Pain Research Center, Aarhus University, Aarhus, Denmark | Danish Pain Research Center, Department of

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