KOL | Matthew MorrisDepartment of Chemistry and Biochemistry, Miami University, Oxford, Ohio, 45056, United States |
KOL Resume for Matthew Morris
| Year | |
|---|---|
| 2017 | Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, 45056, United States |
Matthew Morris: Influence Statistics
| Concept | World rank |
|---|---|
| clinical ndm variants | #20 |
| evolution metallo | #31 |
| zinc scarcity | #35 |
| m154l | #49 |
| ndm4 | #94 |
Open the FULL List in Excel | |
Prominent publications by Matthew Morris
Clinical Variants of New Delhi Metallo-β-Lactamase Are Evolving To Overcome Zinc Scarcity
[ PUBLICATION ]
Use and misuse of antibiotics have driven the evolution of serine β-lactamases to better recognize new generations of β-lactam drugs, but the selective pressures driving evolution of metallo-β-lactamases are less clear. Here, we present evidence that New Delhi metallo-β-lactamase (NDM) is evolving to overcome the selective pressure of zinc(II) scarcity. Studies of NDM-1, NDM-4 (M154L), and NDM-12 (M154L, G222D) demonstrate that the point mutant M154L, contained in 50% of clinical NDM ...
| Known for New Delhi | Clinical Variants | Zinc Scarcity | Β Lactamases | Selective Pressures |
Key People For New Delhi
Matthew Morris:Expert Impact
Concepts for whichMatthew Morrishas direct influence:New delhi, Clinical variants, Zinc scarcity, Delhi metallo, New delhi metalloβlactamase, Clinical ndm variants, Β lactamases, Ndm variants.
Matthew Morris:KOL impact
Concepts related to the work of other authors for whichfor which Matthew Morris has influence:New delhi, Ndm variants, Fitness cost, Sporadic emergence, Clinical setting, Carbapenem resistance, Metallo β.
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