Prominent publications by Elsa Pennese

KOL Index score: 12941

BACKGROUND: Diabetes mellitus (DM) is associated with enhanced lipid peroxidation and persistent platelet activation. We tested the hypothesis that the in vivo formation of the F2-isoprostane 8-iso-prostaglandin (PG)F2alpha, a bioactive product of arachidonic acid peroxidation, is enhanced in DM and contributes to platelet activation.

METHODS AND RESULTS: Urine samples were obtained from 85 diabetic patients and 85 age- and sex-matched healthy subjects for measurement of immunoreactive ...

Known for Platelet Activation |  Diabetes Mellitus |  Vivo Formation |  8 Iso |  Vitamin Supplementation
KOL Index score: 4957

PURPOSE: To prospectively validate the use of a simplified geriatric assessment (sGA) at diagnosis and to integrate it into a prognostic score for older patients with diffuse large B-cell lymphoma (DLBCL).

METHODS: We conducted the prospective Elderly Project study on patients with DLBCL older than 64 years who underwent our Fondazione Italiana Linfomi original geriatric assessment (oGA) (age, Cumulative Illness Rating Scale for Geriatrics, activities of daily living, and instrumental ...

Known for Geriatric Assessment |  Diffuse Large |  Patients Dlbcl |  Cell Lymphoma |  Multivariate Analysis
KOL Index score: 4745

Autoimmune cytopenias (AICs) affect 5% to 9% of patients with chronic lymphocytic leukemia (CLL). Targeted drugs-ibrutinib, idelalisib, and venetoclax-have a prominent role in the treatment of CLL, but their impact on CLL-associated AICs is largely unknown. In this study, we evaluated the characteristics and outcome of preexisting AICs and described the incidence, quality, and management of treatment-emergent AICs during therapy with targeted drugs in patients with CLL. We collected data ...

Known for Targeted Drugs |  Patients Cll |  Venetoclax Therapy |  Treated Ibrutinib |  Anti Cd20

 

Elsa Pennese: Influence Statistics

Sample of concepts for which Elsa Pennese is among the top experts in the world.
Concept World rank
urinary 8isopgf2alpha excretion #31
thromboxane txm #34
txm excretion #66
urinary 8isopgf2alpha #69
pgf2alpha excretion #82
urinary txm #83
arachidonic acid peroxidation #88

Key People For Platelet Activation

Top KOLs in the world
#1
Alan D Michelson
platelet activation flow cytometry aspirin resistance
#2
Sanford J Shattil
alpha iib platelet activation tyrosine phosphorylation
#3
Meinrad Paul Gawaz
platelet activation endothelial cells thrombus formation
#4
Zaverio M Ruggeri
willebrand factor platelet adhesion thrombus formation
#5
Bernhard Nieswandt
thrombus formation platelet activation ischemic stroke
#6
Denisa D Wagner
willebrand factor endothelial cells deep vein thrombosis

Elsa Pennese:Expert Impact

Concepts for whichElsa Pennesehas direct influence:Platelet activation,  Vivo formation,  Geriatric assessment,  Targeted drugs,  Diabetes mellitus,  Patients cll,  Diffuse large,  Patients dlbcl.

Elsa Pennese:KOL impact

Concepts related to the work of other authors for whichfor which Elsa Pennese has influence:Oxidative stress,  Lipid peroxidation,  Diabetes mellitus,  Platelet activation,  Type 2,  Diabetic patients,  Cardiovascular disease.


 

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U.O.S.D. Centro Diagnosi e Terapia dei Linfomi, Dipartimento Oncologico-Ematologico, Presidio Ospedaliero "Spirito Santo", Pescara | Lymphoma Unit, Department of Hematology, Ospedale Spirito Santo, Pescara, Italy. | Unità Operativa Semplice Dipartime

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