• Disease
  • Occupational
  • Occupational Asthma
  • Paul Cullinan

    Prominent publications by Paul Cullinan

    KOL Index score: 17591

    BACKGROUND: Studies of patients admitted to hospital with COVID-19 have found varying mortality outcomes associated with underlying respiratory conditions and inhaled corticosteroid use. Using data from a national, multicentre, prospective cohort, we aimed to characterise people with COVID-19 admitted to hospital with underlying respiratory disease, assess the level of care received, measure in-hospital mortality, and examine the effect of inhaled corticosteroid use.

    METHODS: We analysed ...

    Also Ranks for: Patients Asthma |  inhaled corticosteroids |  hospital covid19 |  adverse outcomes |  pulmonary disease
    KOL Index score: 16513

    BACKGROUND: Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. We aimed to assess the effects on respiratory and cardiovascular responses of walking down a busy street with high levels of ...

    Also Ranks for: Heart Disease |  oxford street |  ultrafine particles |  chronic lung |  black carbon
    KOL Index score: 13124

    BACKGROUND: In fibrotic interstitial lung diseases, exertional breathlessness is strongly linked to health-related quality of life (HRQOL). Breathlessness is often associated with oxygen desaturation, but few data about the use of ambulatory oxygen in patients with fibrotic interstitial lung disease are available. We aimed to assess the effects of ambulatory oxygen on HRQOL in patients with interstitial lung disease with isolated exertional hypoxia.

    METHODS: AmbOx was a prospective, ...

    Also Ranks for: Ambulatory Oxygen |  fibrotic lung |  2 weeks |  life hrqol |  controlled trial
    KOL Index score: 12438

    BACKGROUND: Air pollution from road traffic is a serious health hazard, and people with preexisting respiratory disease may be at increased risk. We investigated the effects of short-term exposure to diesel traffic in people with asthma in an urban, roadside environment.

    METHODS: We recruited 60 adults with either mild or moderate asthma to participate in a randomized, crossover study. Each participant walked for 2 hours along a London street (Oxford Street) and, on a separate occasion, ...

    Also Ranks for: Oxford Street |  hyde park |  respiratory effects |  environmental monitoring |  elemental carbon
    KOL Index score: 12368

    BACKGROUND: Studies on the association of farm environments with asthma and atopy have repeatedly observed a protective effect of farming. However, no single specific farm-related exposure explaining this protective farm effect has consistently been identified.

    OBJECTIVE: We sought to determine distinct farm exposures that account for the protective effect of farming on asthma and atopy.

    METHODS: In rural regions of Austria, Germany, and Switzerland, 79,888 school-aged children answered ...

    Also Ranks for: Farm Asthma |  gabriel advanced studies |  atopic dermatitis |  aor 95 |  fever atopy
    KOL Index score: 12363

    BACKGROUND: Atopy is not uncommon among children living in rural Crete, but wheeze and rhinitis are rare. A study was undertaken to examine whether this discrepancy could be attributed to a high consumption of fresh fruit and vegetables or adherence to a traditional Mediterranean diet.

    METHODS: A cross-sectional survey was performed in 690 children aged 7-18 years in rural Crete. Parents completed a questionnaire on their child's respiratory and allergic symptoms and a 58-item food ...

    Also Ranks for: Mediterranean Diet |  fresh fruit |  atopy children |  allergic rhinitis |  asthma child
    KOL Index score: 11636

    BACKGROUND: Oilseed rape is an important crop grown in the UK which can cause specific immunological sensitization with clinical symptoms in a relatively small number of the general population. Individuals with immunoglobulin (Ig) E-mediated allergy to oilseed rape have also been found to be sensitized to other pollen allergens, most frequently being grass pollen. Cross-reactivity between common grass and oilseed rape would have important implications, especially as their flowering ...

    Also Ranks for: Oilseed Rape |  cross reactivity |  grass pollen |  molecular weights |  blotting western
    KOL Index score: 11600

    BACKGROUND: The aim of this study was to use a longitudinal computerised health care dataset (The Health Improvement Network) to provide information on the overall incidence of cancer, and on the incidence of organ-specific cancers, in people with idiopathic pulmonary fibrosis (IPF) and sarcoidosis in comparison to the general population.

    METHODS: Incident cases of IPF and sarcoidosis were identified with up to four controls matched by age, gender and general practice. Cancer incidence ...

    Also Ranks for: Cancer Incidence |  ipf age |  idiopathic pulmonary fibrosis |  rate ratio |  united kingdom
    KOL Index score: 11525

    BACKGROUND: Hospitalisation for acute exacerbations of COPD is associated with high risk of readmission. However, no tool has been validated to stratify patients at discharge for risk of readmission.

    AIM: To evaluate the ability of the 4 m gait speed (4MGS), a surrogate marker of frailty, to predict risk of future readmission in hospitalised patients with an acute exacerbation of COPD (AECOPD).

    METHODS: 213 patients hospitalised with an AECOPD were recruited prospectively. 4MGS was ...

    Also Ranks for: Acute Exacerbations |  gait speed |  risk readmission |  copd aecopd |  surrogate marker
    KOL Index score: 11369

    Fibrosing alveolitis associated with systemic sclerosis (FASSc) is considered to be histologically and radiologically indistinguishable from lone cryptogenic fibrosing alveolitis (CFA). To date, the natural history of the two diseases has not been compared directly in large groups of patients followed at a single institution. We evaluated the survival of 205 patients with CFA and 68 patients with FASSc. Deaths during the follow-up period were reported in 142 patients with CFA (70%) and ...

    Also Ranks for: Fibrosing Alveolitis |  cfa fassc |  systemic sclerosis |  lone cryptogenic |  11 patients
    KOL Index score: 11001

    BACKGROUND: Occupational asthma is the most frequently reported work related respiratory disease in many countries. This work was commissioned by the British Occupational Health Research Foundation to assist the Health and Safety Executive in achieving its target of reducing the incidence of occupational asthma in Great Britain by 30% by 2010.

    AIM: The guidelines aim to improve the prevention, identification, and management of occupational asthma by providing evidence based ...

    Also Ranks for: Occupational Asthma |  evidence based guidelines |  identification management |  royal college |  health safety executive
    KOL Index score: 10875

    BACKGROUND: Despite scarce scientific evidence, current feeding guidelines recommend delayed introduction of solids for the prevention of asthma and allergy.

    AIMS: To explore whether late introduction of solids is protective against the development of asthma, eczema, and atopy.

    METHODS: A total of 642 children were recruited before birth and followed to the age of 5(1/2) years. Main outcome measures were: doctor's diagnosis of eczema ever, atopy according to skin prick test results ...

    Also Ranks for: Asthma Eczema |  late introduction |  solids development |  feeding guidelines |  evidence protective
    KOL Index score: 10814

    OBJECTIVES: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Exposure to occupational hazards is an important preventable risk factor but the contribution of specific occupations to COPD risk in a general population is uncertain. Our aim was to investigate the association of COPD with occupation in the UK population.

    METHODS: In 2006-2010, the UK Biobank cohort recruited 502 649 adults aged 40-69 years. COPD cases were identified by ...

    Also Ranks for: Copd Risk |  uk biobank |  pulmonary disease |  aged occupational |  prevalence ratios
    KOL Index score: 10748

    BACKGROUND: Although it is widely assumed that childhood sensitization to common aeroallergens is directly related to allergen exposure in early life, few longitudinal studies have investigated this issue, and available data are scarce and mainly limited to high-risk groups.

    OBJECTIVE: We sought to assess the role of early exposure to 2 major household aeroallergens (Der p 1 and Fel d 1) in sensitization at the age of 4 years.

    METHODS: Pregnant women and their children were recruited for ...

    Also Ranks for: Allergen Exposure |  ige sensitization |  early life |  1 levels |  dust samples
    KOL Index score: 10343

    BACKGROUND: Asthma is a disease in which both genetic and environmental factors play important roles. The farming environment has consistently been associated with protection from childhood asthma and atopy, and interactions have been reported with polymorphisms in innate immunity genes.

    OBJECTIVE: To detect gene-environment interactions for asthma and atopy in the farming environment.

    METHODS: We performed a genome-wide interaction analysis for asthma and atopy by using 500,000 ...

    Also Ranks for: Childhood Asthma |  farming environment |  farm exposures |  genome wide |  single nucleotide


    Paul Cullinan: Influence Statistics

    Sample of concepts for which Paul Cullinan is among the top experts in the world.
    Concept World rank
    exercise elite level #1
    genotype details #1
    persulphates antibiotics #1
    bohrf #1
    pattern fvc #1
    rural crete wheeze #1
    flour fungal alpha #1
    children rural crete #1
    generic control measures #1
    proven diagnostic benefit #1
    protease exposure employees #1
    sensitization improver #1
    cellulase lipase #1
    67 72 workers #1
    1984 bhopal #1
    medical surveillance prevention #1
    moderate evidence metal #1
    eczema outcomes age #1
    ocs clinical outcomes #1
    preserved 4mgs #1
    copd specific exposures #1
    predictive behaviour methods #1
    skin prick responses #1
    direct asthmarelated outcomes #1
    sic postchallenge increase #1
    clinical allergy figures #1
    prevalence sensitisation #1
    lung function welders #1
    oxford transport #1
    potential new employees #1
    paneuropean task force #1
    efficient explanation distribution #1
    potential alternative detection #1
    retrospective studies hmw #1
    geographic clustering deaths #1
    parent asthmas diagnosis #1
    community intermediate prevalence #1
    nonelective hospitalisation #1
    sporadic single year #1
    immunological sensitisation #1
    referral adult clinic #1
    centres service #1
    asthma firefighter applicants #1
    improver enzyme #1
    occupational asthma europe #1
    single linked machine #1
    sibship allergic disease #1
    introduction mesotheliomaattributionfurther #1
    melanogaster sensitisation #1
    hla disparity mother #1

    Key People For Occupational Asthma

    Top KOLs in the world
    André Cartier
    occupational asthma bronchial responsiveness psychiatric disorders
    Jean‐Luc Malo
    occupational asthma guar gum bronchial responsiveness
    Moira M W Chan‐Yeung
    hong kong occupational asthma british columbia
    Peter Sherwood Burge
    occupational asthma west midlands fluticasone propionate
    JeanLuc Malo
    occupational asthma bronchial responsiveness cold air
    Susan Mary Tarlo
    occupational asthma chronic cough respiratory symptoms

    Paul Cullinan:Expert Impact

    Concepts for whichPaul Cullinanhas direct influence:Occupational asthma,  Sickness absence,  Ambulatory oxygen,  United kingdom,  Lung function,  Cystic fibrosis,  Allergen exposure,  Uk biobank.

    Paul Cullinan:KOL impact

    Concepts related to the work of other authors for whichfor which Paul Cullinan has influence:Occupational asthma,  Allergic rhinitis,  Air pollution,  Cystic fibrosis,  Lung cancer,  Atopic dermatitis,  Particulate matter.



    Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

    Genomic and Environmental Medicine, National Heart and Lung Institute, Imperial College London, UK. | Imperial College London, 4615, National Heart and Lung Institute, London, United Kingdom of Great Britain and Northern Ireland. | National Heart and