• Disease
  • Olfactory
  • Olfactory Function
  • Thomas C Hummel

    Prominent publications by Thomas C Hummel

    KOL Index score: 13205

    Abstract“Sniffin’ Sticks” is a test of nasal chemosensory function that is based on pen-like odor dispensing devices, introduced some 10 years ago by Kobal and co-workers. It consists of tests for odor threshold, discrimination, and identification. Previous work established its test-retest reliability and validity. Results of the test are presented as “TDI score”, the sum of results obtained for threshold, discrimination, and identification measures. While normative data have been ...

    Also Ranks for: Odor Discrimination |  normative data |  olfactory thresholds |  sniffin sticks |  55 years
    KOL Index score: 12469

    Abstract“Sniffin’ Sticks” is a test of nasal chemosensory performance that is based on penlike odor-dispensing devices. It is comprised of three tests of olfactory function: tests for odor threshold, discrimination and identification. Previous work has already established its test-retest reliability and validity in comparison to established measures of olfactory sensitivity. The results of this test are presented as a composite TDI score – i.e., the sum of results obtained for threshold, ...

    Also Ranks for: Olfactory Function |  odor identification |  tdi score |  subjects 55 years |  anosmic patients
    KOL Index score: 12219

    OBJECTIVE/HYPOTHESIS: This prospective study aimed to investigate predictors of nasal surgery in terms of olfactory function.

    STUDY DESIGN: Prospective study.

    METHODS: A total of 775 patients were included in this prospective study (482 men, 293 women; age range 10-81 years, mean age 41 years, standard deviation = 15.3 y). Prior to surgery, patients received a detailed otorhinolaryngologic examination including nasal endoscopy. Olfactory function was assessed with a standardized odor ...

    Also Ranks for: Olfactory Function |  nasal surgery |  patients improvement |  sinus diseases |  olfaction disorders
    KOL Index score: 12065

    OBJECTIVES: Olfactory function is known to be modulated by repeated exposure to odors. The aim of this investigation was whether patients with olfactory loss would benefit from "Training" with odors in terms of an improvement of their general olfactory function. It was hypothesized that olfactory Training should produce both an improved sensitivity towards the odors used in the Training process and an overall increase of olfactory function.

    STUDY DESIGN: The prospective study was ...

    Also Ranks for: Olfactory Training |  phenyl ethyl alcohol |  thresholds odors |  12 weeks |  repeated exposure
    KOL Index score: 11920

    BACKGROUND: On the basis of experiments in rats, serotonin 4 receptor (5-hydroxytryptamine 4 [5-HT4]) agonists have been proposed as a novel therapeutic strategy for the selective treatment of respiratory depression caused by opioids while leaving analgesic effects unaffected. The effects in rats have been seen with the 5-hydroxytryptamine 4a (5-HT4a) agonist BIMU8, which is currently not available for use in humans.

    METHODS: In a proof-of-applicability study, the clinically recommended ...

    Also Ranks for: Respiratory Depression |  morphine rats |  spraguedawley receptors |  receptor agonist |  analgesic effects
    KOL Index score: 11748

    OBJECTIVE: To clarify the olfactory deficit hypothesis regarding Alzheimer's disease, the authors compared olfactory function in patients with Alzheimer's disease, subjects with mild cognitive impairment, and healthy comparison subjects.

    METHOD: Olfactory function of 14 patients with mild Alzheimer's disease, eight subjects with mild cognitive impairment, and eight healthy age-matched comparison subjects was assessed with both psychophysical tests and olfactory event-related ...

    Also Ranks for: Alzheimers Disease |  mild cognitive impairment |  olfactory function |  patients alzheimer |  odor discrimination
    KOL Index score: 11575

    OBJECTIVE: To investigate the outcome of olfactory function in patients with olfactory loss following infections of the upper respiratory tract (post-URTI) or head trauma.

    DESIGN: Retrospective patient-based study.

    SETTING: Smell and Taste Outpatient Clinic at a university hospital.

    PATIENTS: A total of 361 patients (228 women, 133 men) were included.

    MAIN OUTCOME MEASURES: Olfactory function was assessed using the "Sniffin' Sticks" test battery, which result in a threshold, ...

    Also Ranks for: Olfactory Function |  upper respiratory tract |  10 patients |  threshold discrimination |  head trauma
    KOL Index score: 11281

    OBJECTIVE: For chemosensory event-related potentials (ERP) significant effects of age and sex have been demonstrated. The aim of the present study was to assess the effects of stimulus concentration, side of stimulation, and sex on the topographical distribution of chemosensory ERP in a large group of subjects stratified for different age groups. In addition, psychophysical measures of both olfactory and trigeminal function should be assessed in greater detail compared to previous ...

    Also Ranks for: Stimulus Concentration |  olfactory trigeminal |  chemosensory event |  sex factors |  potentials erp
    KOL Index score: 11211

    Although Parkinson’s disease (PD) is usually considered as a movement disorder, it is strongly associated with non-motor symptoms (NMS), including smell and taste dysfunctions, cognitive impairment, apathy, fatigue, and autonomic dysregulation. Olfactory deficit is considered the most common NMS in PD preceding the motor symptoms for years. The aim of this study was to investigate olfactory function, cognitive impairment, apathy, and fatigue in patients with PD in comparison with healthy ...

    Also Ranks for: Cognitive Impairment |  olfactory function |  fatigue patients |  parkinson disease |  odor identification
    KOL Index score: 11145

    OBJECTIVE: To investigate whether differences in olfactory function between healthy individuals and patients with olfactory loss could be detected by various diagnostic tests.

    DESIGN: Psychophysical testing of orthonasal and retronasal olfactory functions, magnetic resonance imaging of olfactory bulb (OB) volume, and chemosensory event-related potential (ERP) measurement performed between January 1, 2005, and October 31, 2005.

    SETTING: Academic tertiary referral medical center.

    PATIENTS: ...

    Also Ranks for: Olfactory Function |  retronasal testing |  bulb volume |  healthy individuals |  chemosensory event
    KOL Index score: 11036

    PURPOSE: Smell and taste changes during chemotherapy are significant complaints of cancer patients. Loss of olfactory/gustatory function can lead to malnutrition, weight loss, and possibly a prolonged morbidity of chemotherapy-induced adverse effects, decreased quality of life, poor compliance, and even decreased therapy response. This prospective study comprehensively investigated, to our knowledge for the first time, smell and taste changes in a cohort of 87 patients undergoing ...

    Also Ranks for: Breast Cancer |  olfactory function |  taste smell |  gynecologic malignancies |  quality life
    KOL Index score: 10855

    The present investigation aimed to compare trigeminal nasal function of anosmic and hyposmic patients to healthy controls. Further, we aimed to study effects of age and gender on trigeminally mediated sensations following intranasal chemosensory stimulation. Participants were 35 patients with olfactory dysfunction (n=13: functional anosmia; n=22: hyposmia; age 28-69 years, mean age 56 years). Their results were compared with 17 normosmic subjects (28-82 years, mean 52 years). To analyze ...

    Also Ranks for: Olfactory Function |  chemosensory stimuli |  trigeminal sensitivity |  lower scores |  effects age
    KOL Index score: 10622

    OBJECTIVE: The aims of this study were to evaluate olfactory function with orthonasal and retronasal testing in patients with posttraumatic olfactory loss and to investigate the relation between residual olfactory function and olfactory bulb (OB) volume.

    METHOD: A retrospective study of 25 patients with posttraumatic olfactory loss was performed. Orthonasal olfactory function was assessed with the Sniffin' Sticks test kit; retronasal olfactory function was assessed with intraorally ...

    Also Ranks for: Olfactory Function |  patients parosmia |  bulb volume |  orthonasal retronasal |  magnetic resonance imaging
    KOL Index score: 10550

    The aim of this study was to investigate the accuracy of self-reported ratings of olfactory function in 83 healthy subjects. Such ratings were compared with quantitative measures of olfactory function, as well as with ratings of nasal patency. In experiment 1 subjects rated olfactory function and nasal patency before olfactory testing, whereas in experiment 2 the reverse was the case. No feedback regarding test results were provided until after completion of the testing. The principal ...

    Also Ranks for: Olfactory Function |  nasal patency |  correlation ratings |  daily life |  quantitative measures
    KOL Index score: 10480

    Dscam is an immunoglobulin (Ig) superfamily member that regulates axon guidance and targeting in Drosophila. Alternative splicing potentially generates 38,016 isoforms differing in their extracellular Ig and transmembrane domains. We demonstrate that Dscam mediates the sorting of axons in the developing mushroom body (MB). This correlates with the precise spatiotemporal pattern of Dscam protein expression. We demonstrate that MB neurons express different arrays of Dscam isoforms and that ...

    Also Ranks for: Axon Guidance |  dscam diversity |  drosophila mushroom |  mb neurons |  extracellular domains


    Thomas C Hummel: Influence Statistics

    Sample of concepts for which Thomas C Hummel is among the top experts in the world.
    Concept World rank
    minty chewing #1
    study volume #1
    olfactory function pregnancy #1
    processing intranasal #1
    disease spectrum scd #1
    cued odor #1
    nasal surgery predictors #1
    participants rose odor #1
    duration olfactory dysfunction #1
    sensory thresholds smell #1
    responders volume #1
    nostril opening #1
    hyposmia gm density #1
    nerve adult #1
    differences olfactory function #1
    volume insula #1
    dream emotions processing #1
    sensitivity taste #1
    57y #1
    eog recordings #1
    human chemosensory communication #1
    o15h2opet #1
    female humans parosmia #1
    specific anosmia odorants #1
    patients normosmic #1
    olfactory loss deficits #1
    study olfactory sensitivity #1
    controls pleasantness scores #1
    intensity ratings oerp #1
    sfp cst #1
    improvement odour discrimination #1
    olfactory tests groups #1
    tegmental neural #1
    agitation cognitive decline #1
    localization vno #1
    lower olfactory #1
    improvement olfaction #1
    bolivian rainforest #1
    correlation olfactory #1
    training olfactory #1
    co2 nostril #1
    3hydrox2methyl4pyrone #1
    retronasal olfactory function #1
    odors ability #1
    trigeminal stimulants #1
    olfactory scores #1
    olfactory event #1

    Key People For Olfactory Function

    Top KOLs in the world
    Thomas C Hummel
    olfactory function odor identification taste disorders
    Richard L Doty
    olfactory dysfunction pennsylvania smell odor identification
    Gerd Kobal
    nasal mucosa evoked potentials odor identification
    Hilmar Gudziol
    olfactory bulb lamination patterns gustatory function
    Elisabeth Pauli
    temporal lobe wada test epilepsy surgery
    Stephan Rüdiger Wolf
    facial nerve olfactory performance acoustic neurinomas

    Thomas C Hummel:Expert Impact

    Concepts for whichThomas C Hummelhas direct influence:Olfactory function,  Olfactory dysfunction,  Olfactory loss,  Olfactory bulb,  Olfactory training,  Odor identification,  Gustatory function,  Olfactory disorders.

    Thomas C Hummel:KOL impact

    Concepts related to the work of other authors for whichfor which Thomas C Hummel has influence:Olfactory dysfunction,  Parkinson disease,  Postoperative delirium,  Chronic rhinosinusitis,  Odor identification,  Taste disorders,  Smell loss.



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    Smell and Taste Clinic, Department of Otorhinolaryngology, University of Dresden Medical School, Dresden, Germany | Department of Otorhinolaryngology, Technische Universität Dresden, Smell and Taste Clinic, Dresden, Germany | Smell & Taste Clinic, De