Prominent publications by Philippe Cabre

KOL Index score: 10094

OBJECTIVE: In this study, we compared the effectiveness of teriflunomide (TRF) and dimethyl fumarate (DMF) on both clinical and MRI outcomes in patients followed prospectively in the Observatoire Français de la Sclérose en Plaques.

METHODS: A total of 1,770 patients with relapsing-remitting multiple sclerosis (RRMS) (713 on TRF and 1,057 on DMF) with an available baseline brain MRI were included in intention to treat. The 1- and 2-year postinitiation outcomes were relapses, increase of ...

Known for Dimethyl Fumarate |  Trf Dmf |  Comparative Effectiveness |  Multiple Sclerosis |  Patients Rrms
KOL Index score: 9923

OBJECTIVE: To compare natalizumab and fingolimod on both clinical and MRI outcomes in patients with relapsing-remitting multiple sclerosis (RRMS) from 27 multiple sclerosis centers participating in the French follow-up cohort Observatoire of Multiple Sclerosis.

METHODS: Patients with RRMS included in the study were aged from 18 to 65 years with an Expanded Disability Status Scale score of 0-5.5 and an available brain MRI performed within the year before treatment initiation. The data ...

Known for Natalizumab Fingolimod |  Patients Rrms |  Year Treatment |  Comparative Efficacy |  New Lesions
KOL Index score: 8482

Background: Guillain-Barré syndrome (GBS) has been reported to be associated with Zika virus (ZIKV) infection in case reports and retrospective studies, mostly on the basis of serological tests, with the problematic cross-reacting antibodies of the Flavivirus genus. Some GBS cases do not exhibit a high level of diagnostic certainty. This prospective study aimed to describe the clinical profiles and the frequency of GBS associated with ZIKV during the ZIKV outbreak in Martinique in ...

Known for Zika Virus |  Zikv Infection |  Gbs Cases |  Barré Syndrome |  Interquartile Range
KOL Index score: 4613

Neuromyelitis optica (NMO) (and NMO spectrum disorder) is an autoimmune inflammatory disease of the CNS primarily affecting spinal cord and optic nerves. Reliable and sensitive biomarkers for onset, relapse, and progression in NMO are urgently needed because of the heterogeneous clinical presentation, severity of neurologic disability following relapses, and variability of therapeutic response. Detecting aquaporin-4 (AQP4) antibodies (AQP4-IgG or NMO-IgG) in serum supports the diagnosis ...

Known for Neuromyelitis Optica |  Spinal Cord |  Optic Nerves |  Seropositive Nmo |  Potential Biomarkers
KOL Index score: 4467

Background: Steps towards the development of diagnostic criteria are needed for children with the radiologically isolated syndrome to identify children at risk of clinical demyelination.

Objectives: To evaluate the 2005 and 2016 MAGNIMS magnetic resonance imaging criteria for dissemination in space for multiple sclerosis, both alone and with oligoclonal bands in cerebrospinal fluid added, as predictors of a first clinical event consistent with central nervous system demyelination in ...

Known for Oligoclonal Bands |  Radiologically Isolated Syndrome |  Multiple Sclerosis |  Clinical Event |  42 ±
KOL Index score: 3717

Multiple sclerosis (MS) disease risk is associated with reduced sun-exposure. This study assessed the relationship between measures of sun exposure (vitamin D [vitD], latitude) and MS severity in the setting of two multicenter cohort studies (n NationMS = 946, n BIONAT = 990). Additionally, effect-modification by medication and photosensitivity-associated MC1R variants was assessed. High serum vitD was associated with a reduced MS severity score (MSSS), reduced risk for relapses, and ...

Known for Multiple Sclerosis |  Sun Exposure |  Immune Cells |  Immunomodulatory Effects |  Association Latitude
KOL Index score: 3503

In multiple sclerosis, treatment start or switch is prompted by evidence of disease activity. Whilst immunomodulatory therapies reduce disease activity, the time required to attain maximal effect is unclear. In this study we aimed to develop a method that allows identification of the time to manifest fully and clinically the effect of multiple sclerosis treatments ('therapeutic lag') on clinical disease activity represented by relapses and progression-of-disability events. Data from two ...

Known for Multiple Sclerosis |  Therapeutic Lag |  Disability Progression |  Treatment Disease |  Immunologic Factors


Philippe Cabre: Influence Statistics

Sample of concepts for which Philippe Cabre is among the top experts in the world.
Concept World rank
dmf clinical effectiveness #26
dmftreated patients relapses #26
rrms trf #26
patients dmftreated patients #26
trf dimethyl fumarate #26
2 years dmf #27
effectiveness teriflunomide #32
martinique gbs #34
outcomes dmf #40
criteria radiologically #42
treatment trf #42
trf dimethyl #44
compared trf #45
treatment discontinuation lack #48
teriflunomide trf #48
dmf trf #56
trf dmf #56
patients trf #61
trf treated #62
trf compared #64
effectiveness dmf #74
français sclérose #83
lower dmf #86
gbs zikv infection #89
dmf clinical #94
observatoire français #95
compared dmf #97
dmftreated patients #97
relapses increase #98

Key People For Oligoclonal Bands

Top KOLs in the world
Hans Link
multiple sclerosis myasthenia gravis dendritic cells
Wallace W Tourtellotte
multiple sclerosis cerebrospinal fluid situ hybridization
Alanda K Thompson
multiple sclerosis spinal cord magnetic resonance
Hans‐Peter Hartung
multiple sclerosis chronic inflammatory schwann cells
Fred D Lublin
multiple sclerosis glatiramer acetate monoclonal antibodies
Sten Öhman
multiple sclerosis cerebrospinal fluid ionized calcium

Philippe Cabre:Expert Impact

Concepts for whichPhilippe Cabrehas direct influence:Oligoclonal bands,  Radiologically isolated syndrome,  Disability progression,  Patients rrms,  Dimethyl fumarate,  Multiple sclerosis,  Natalizumab fingolimod,  Fingolimod natalizumab.

Philippe Cabre:KOL impact

Concepts related to the work of other authors for whichfor which Philippe Cabre has influence:Multiple sclerosis,  Neuromyelitis optica,  Zika virus,  Dimethyl fumarate,  Natalizumab fingolimod,  Zikv infection,  Patients nmosd.



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