Nancy J Newman
Department of Ophthalmology. | Department of Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia, USA. | Departments of Ophthalmology, Neurology and ...
KOL Resume for Nancy J Newman
Department of Ophthalmology.
LeoDelle Jolley Chair in Ophthalmology Director, Section of Neuro-ophthalmology, Professor of Ophthalmology and Neurology, Instructor of Neurological Surgery, Emory University School of Medicine, Atlanta, GA, USA
Departments of Neurology and Ophthalmology (MLM, RCS, AAD), Wills Eye Hospital and Thomas Jefferson University, Philadelphia, Pennsylvania; Departments of Ophthalmology (NJN, VB), Neurology and Neurological Surgery, Emory University School of Medicine, Atlanta, Georgia; Cambridge Centre for Brain Repair and MRC Mitochondrial Biology Unit (PY-W-M), Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom; Cambridge Eye Unit (PY-W-M), Addenbrooke's Hospital, Cambridge University Hospitals, Cambridge, United Kingdom; Moorfields Eye Hospital (PY-W-M), London, United Kingdom; UCL Institute of Ophthalmology (PY-W-M), University College London, London, United Kingdom; IRCCS Istituto Delle Scienze Neurologiche di Bologna (VC, MC), UOC Clinica Neurologica, Bologna, Italy; Unit of Neurology (VC), Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy; Institute of Health Research and Policy (MSB), University of Illinois, Chicago, Chicago, Illinois; Statistics Consultant (GS), GenSight Biologics, CaliforniaDepartment of Neuro Ophthalmology and Emergencies (CV-C, RH), Rothschild Foundation Hospital, Paris, France; Centre Hospitalier National D'Ophtalmologie des Quinze Vingts (CV-C, RH), Paris, France; Department of Neurology (TK), Friedrich-Baur-Institute, University Hospital, LMU Munich, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE) (TK), Munich, Germany; Munich Cluster for Systems Neurology (SyNergy) (TK), Munich, Germany; Doheny Eye Center UCLA (AAS, RK), Department of Ophthalmology David Geffen School of Medicine at UCLA, Doheny Eye Institute, Los Angeles, CaliforniaDepartment of Ophthalmology (SP), University Hospital, LMU Munich, Munich, Germany, ; Department of Ophthalmology (RK), University of Ottawa Eye Institute, Ottawa, Canada, ; GenSight Biologics (LB, MT), Paris, France; Medical Consultant (BK), GenSight Biologics; Sorbonne Université (JAS), INSERM, CNRS, Institut de La Vision, 75012 Paris, France, ; Fondation Ophtalmologique A. de Rothschild (JAS), 25-29 Rue Manin, Paris; Department of Ophthalmology (JAS), the University of Pittsburgh School of Medicine, PittsburghCHNO des Quinze-Vingts (JAS), Institut Hospitalo-Universitaire FOReSIGHT, INSERM-DGOS CIC 1423, Paris, France.
Department of Ophthalmology, Emory University School of Medicine, 1365B Clifton Rd NE, 30322, Atlanta, GA, USA
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, United States
Emory University School of Medicine, Atlanta, USA
Ophthalmology, Neurology and Neurological Surgery
Departments of Ophthalmology (SB, NJN, and VB), Otolaryngology-Head and Neck Surgery (JML), Radiology and Imaging Sciences (AMS), Neurological Surgery (NMO and NJN), and Neurology (NJN and VB), Emory University School of Medicine, Atlanta, Georgia.
Department of Neurological Surgery.
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
Ophthalmology, Emory University, Atlanta, Georgia, USA; Neurology, Emory University, Atlanta, Georgia, USA; Neurological Surgery, Emory University, Atlanta, Georgia, USA, View further author information
Department of Ophthalmology, Emory University School of Medicine, 1365-B Clifton Road, Northeast, Atlanta, GA 30322, USA
Ophthalmology (N.J.N., V.B., B.B.B.), Emory University, Atlanta, Georgia
Department of Neurological Surgery, Emory University Hospital, Emory University School of Medicine, Atlanta, GA, USA
From the Departments of Ophthalmology (L.N.V., P.T., V.B., P.G., N.J.N., B.B.B.), Neurology (V.B., N.J.N., B.B.B.), Emergency Medicine (D.W.W.), and Neurological Surgery (N.J.N.), Emory University, Atlanta, GA.
Department of Neurology, Emory University, Atlanta, Georgia
Departments of Neurology, Ophthalmology, and Neurosurgery (DDM), Indiana University School of Medicine, Indianapolis, IN. Departments of Ophthalmology (PSG, BBB, NJN, VB), Neurology (BBB, NJN, VB), and Neurological Surgery (NJN), Emory University School of Medicine; and Department of Epidemiology (BBB), Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, GA.
Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA
Nancy J Newman: Influence Statistics
|challenge publication humans||#1|
|visual function csfop||#1|
|patients dense imaging||#1|
|ischemic optic neuropathies||#1|
|osa iih patients||#1|
|variety socalled designer||#1|
|bilateral optic neuropathies||#1|
|hereditary optic vision||#1|
|atypical presentations iih||#1|
|referrals 300 patients||#1|
|papilledema vitreous hemorrhage||#1|
|essential role identification||#1|
|050 db reduction||#1|
|2 retinal detachments||#1|
|brao crao patients||#1|
|catheter angiography numerous||#1|
|optic neuropathies case||#1|
|eye specialists patients||#1|
|nmfp ocular diseases||#1|
|blood loss percentage||#1|
|radiographic signs sella||#1|
|review endovascular coiling||#1|
|29 iih patients||#1|
|mayfield pins percentage||#1|
|pontine displacement patients||#1|
|86 165 patients||#1|
|majority ion patients||#1|
|role nd5 gene||#1|
|neuroophthalmologic conditions evaluation||#1|
|proposed treatments naion||#1|
|highrisk bq score||#1|
|temporal pallor eyes||#1|
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Prominent publications by Nancy J Newman
Profiles of Obesity, Weight Gain, and Quality of Life in Idiopathic Intracranial Hypertension (Pseudotumor Cerebri)
[ PUBLICATION ]
PURPOSE: Obesity and weight gain are known risk factors for idiopathic intracranial hypertension (IIH; or pseudotumor cerebri). The authors examined profiles of body mass index (BMI) and patterns of weight gain associated with IIH. They also examined vision-specific health-related quality of life (HRQOL) in newly diagnosed IIH patients and explored the relative contribution of obesity and weight gain to overall HRQOL in this disorder.
DESIGN: Matched case-control study.
METHODS: Female ...
|Known for Weight Gain | Pseudotumor Cerebri | Iih Life | Body Mass Bmi | Cerebrospinal Fluid Pressure|
Primary Spontaneous Cerebrospinal Fluid Leaks and Idiopathic Intracranial Hypertension
[ PUBLICATION ]
INTRODUCTION: Idiopathic intracranial hypertension (IIH) is increasingly recognized as a cause of spontaneous cerebrospinal fluid (CSF) leak in the otolarnygological and neurosurgical literature. The diagnosis of IIH in patients with spontaneous CSF leaks typically is made a few weeks after surgical repair of the leak when symptoms and signs of elevated intracranial pressure (ICP) appear.
METHODS: Case reports and literature review. Two young obese women developed spontaneous CSF ...
|Known for Csf Leak | Cerebrospinal Fluid | Intracranial Hypertension | Icp Patients | Literature Review|
The fellow eye in naion: report from the ischemic optic neuropathy decompression trial follow-up study1 1InternetAdvance publication at ajo.com June 5, 2002.
[ PUBLICATION ]
PURPOSE: To examine the prevalence and incidence of second eye nonarteritic anterior ischemic optic neuropathy (NAION) and associated patient characteristics in patients enrolled in the Ischemic Optic Neuropathy Decompression Trial (IONDT) Follow-up Study.
DESIGN: Randomized clinical trial with observational cohort.
METHODS: Patients randomized to optic nerve sheath decompression surgery or careful follow-up had a diagnosis of acute unilateral NAION, visual acuity between 20/64 and light ...
|Known for Fellow Eye | Optic Neuropathy | Visual Acuity | Decompression Trial | Baseline Patients|
PURPOSE: To determine medical student preferences for learning the ocular fundus examination and to assess their accuracy using different examination modalities.
DESIGN: Prospective, randomized study of medical student education approaches.
METHODS: First-year medical students received training in direct ophthalmoscopy using simulators and human volunteers. Students were randomized to receive vs not receive specific training on interpreting fundus photographs prior to accuracy ...
|Known for Medical Students | Direct Ophthalmoscopy | Ocular Fundus | Totems Study | Physical Examination|
PURPOSE: To use static threshold perimetry to examine the stages of improvement and the potential for late improvement of visual fields after surgical resection of pituitary adenomas causing visual loss from compression of the anterior visual pathways.
METHODS: Retrospective review of charts of patients with pituitary tumors and abnormal static threshold perimetry before or soon after treatment who had subsequent visual fields. Quantification of the visual field mean deviation overall, ...
|Known for Visual Fields | Pituitary Tumor Resection | 1 Week | Relative Improvement | 2 Years|
BACKGROUND: Acute isolated optic neuritis is often the first manifestation of multiple sclerosis (MS), and its management remains controversial. Over the past decade, with the advent of new disease-modifying agents, management of isolated optic neuritis has become more complicated.
OBJECTIVES: To evaluate the current practice patterns of Canadian ophthalmologists and neurologists in the management of acute optic neuritis, and to evaluate the impact of recently published randomized ...
|Known for Optic Neuritis | Neurologists Ophthalmologists | Management Acute | Multiple Sclerosis | Magnetic Resonance Imaging|
Epidemic Neuropathy in Cuba Not Associated With Mitochondrial DNA Mutations Found in Leber's Hereditary Optic Neuropathy Patients
[ PUBLICATION ]
An epidemic neuropathy in Cuba has caused bilateral optic neuropathies in more than 26,000 people during the past three years. Various pathogenetic factors have been proposed, including toxins, nutritional deficiencies, and an underlying genetic predisposition involving mitochondrial DNA. As part of a case-control collaborative investigation, 135 Cuban blood samples were analyzed for the most common mitochondrial DNA mutations associated with Leber's hereditary optic neuropathy. None of ...
|Known for Mitochondrial Dna | Epidemic Neuropathy | Hereditary Optic | Nutritional Deficiencies | Visual Loss|
Do Most Patients With a Spontaneous Cerebrospinal Fluid Leak Have Idiopathic Intracranial Hypertension?
[ PUBLICATION ]
BACKGROUND: The association between cerebrospinal fluid (CSF) leaks at the skull base and raised intracranial pressure (ICP) has been reported since the 1960s. It has been suggested that spontaneous CSF leaks might represent a variant of idiopathic intracranial hypertension (IIH). We review the evidence regarding the association between spontaneous CSF leaks and IIH, and the role of ICP in the pathophysiology of nontraumatic skull base defects. We also discuss the management of ICP in ...
|Known for Intracranial Hypertension | Cerebrospinal Fluid | Skull Base | Spontaneous Csf Leaks | Patients Iih|
Diagnostic Accuracy and Use of Nonmydriatic Ocular Fundus Photography by Emergency Physicians: Phase II of the FOTO-ED Study
[ PUBLICATION ]
STUDY OBJECTIVE: During the first phase of the Fundus Photography vs Ophthalmoscopy Trial Outcomes in the Emergency Department study, 13% (44/350; 95% confidence interval [CI] 9% to 17%) of patients had an ocular fundus finding, such as papilledema, relevant to their emergency department (ED) management found by nonmydriatic ocular fundus photography reviewed by neuro-ophthalmologists. All of these findings were missed by emergency physicians, who examined only 14% of enrolled patients ...
|Known for Fundus Photography | Emergency Physicians | Nonmydriatic Ocular | Direct Ophthalmoscopy | Sensitivity 95|
The Berlin Questionnaire Screens for Obstructive Sleep Apnea in Idiopathic Intracranial Hypertension
[ PUBLICATION ]
BACKGROUND: Obstructive sleep apnea (OSA) may be associated with idiopathic intracranial hypertension (IIH), a disorder most commonly occurring in young obese women. Because polysomnography, the standard test for diagnosing OSA, is expensive and time consuming, questionnaires have been developed to identify persons with OSA. The Berlin questionnaire (BQ) reliably identifies middle-aged and older persons in the community who are at high-risk for OSA. We aimed to validate the BQ as a ...
|Known for Sleep Apnea | Berlin Questionnaire | Osa Polysomnography | Iih Patients | Intracranial Hypertension|
Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset
[ PUBLICATION ]
PURPOSE: To evaluate the efficacy of a single intravitreal injection of rAAV2/2-ND4 in subjects with visual loss from Leber hereditary optic neuropathy (LHON).
DESIGN: RESCUE is a multicenter, randomized, double-masked, sham-controlled, phase 3 clinical trial.
PARTICIPANTS: Subjects with the m.11778G>A mitochondrial DNA mutation and vision loss ≤6 months from onset in 1 or both eyes were included.
METHODS: Each subject's right eye was randomly assigned (1:1) to treatment with rAAV2/2-ND4 ...
|Known for Leber Hereditary | Raav2 2nd4 | Intravitreal Gene Therapy | Vision Loss | Treated Eyes|
Ischemic optic neuropathy following spine surgery.
[ PUBLICATION ]
Perioperative visual loss (POVL) is a devastating injury that has been reported infrequently after nonocular surgery. The most common cause of POVL is ischemic optic neuropathy (ION). Increasing numbers of cases of ION are being reported after spine surgery, but the etiology of postoperative ION remains poorly understood. After a MEDLINE search of the literature, we reviewed published case reports of ION, specifically those reported after spine surgery performed with the patient in the ...
|Known for Spine Surgery | Optic Neuropathy | Postoperative Ion | Blood Loss | Operative Time|
Visual Outcomes in Leber Hereditary Optic Neuropathy Patients With the m.11778G>A (MTND4) Mitochondrial DNA Mutation.
[ PUBLICATION ]
BACKGROUND: Leber hereditary optic neuropathy (LHON) is a maternally inherited bilaterally blinding optic neuropathy, predominantly affecting otherwise healthy young individuals, mostly men. The visual prognosis is generally poor, with most patients worsening to at least 20/200 visual acuity. The m.11778G>A (MTND4) mitochondrial DNA mutation is the most common cause of LHON and is associated with poor outcomes and limited potential for meaningful visual recovery. Treatments for LHON are ...
|Known for Leber Hereditary | Optic Neuropathy | Lhon Patients | Visual Outcomes | Mitochondrial Dna|
Brain Imaging in Idiopathic Intracranial Hypertension
[ PUBLICATION ]
BACKGROUND: The primary role of brain imaging in idiopathic intracranial hypertension (IIH) is to exclude other pathologies causing intracranial hypertension. However, subtle radiologic findings suggestive of IIH have emerged with modern neuroimaging. This review provides a detailed description of the imaging findings reported in IIH and discusses their possible roles in the pathophysiology and the diagnosis of IIH.
EVIDENCE ACQUISITION: References were identified by searches of PubMed ...
|Known for Intracranial Hypertension | Imaging Findings Iih | Pseudotumor Cerebri | Optic Nerve | Computed Tomography|
Key People For Optic Neuropathy
Nancy J Newman:Expert Impact
Concepts for whichNancy J Newmanhas direct influence:Optic neuropathy, Optic nerve, Intracranial hypertension, Diagnostic error, Visual loss, Lenadogene nolparvovec, Hereditary optic, Optic neuritis.
Nancy J Newman:KOL impact
Concepts related to the work of other authors for whichfor which Nancy J Newman has influence:Optic nerve, Intracranial hypertension, Multiple sclerosis, Visual loss, Mitochondrial dna, Magnetic resonance, Pseudotumor cerebri.
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