• Disease
  • Tinea
  • Tinea Pedis
  • Nardo Zaias

    Prominent publications by Nardo Zaias

    KOL Index score: 9745

    BACKGROUND: Inverse psoriasis can be difficult to treat because of the high sensitivity of intertriginous areas to cutaneous side effects, such as irritation and striae. Pimecrolimus, a well-tolerated, nonatrophogenic, skin-selective inflammatory cytokine inhibitor, has been shown to be effective in the treatment of psoriasis when applied topically under occlusion.

    OBJECTIVE: This study evaluated the efficacy and safety of pimecrolimus cream 1% versus vehicle twice a day in the treatment ...

    Also Ranks for: Pimecrolimus Cream |  intertriginous psoriasis |  1 treatment |  vehicle week |  target area score
    KOL Index score: 7344

    A new method for assessing drug effectiveness in onychomycosis is presented. It is based on the clinical experience when three systemic antifungal drugs (griseofulvin, thiabendazole, and ketoconazole) are used against onychomycosis. These drugs act clinically as a barrier to the invasion of the fungus toward the proximal areas of the nail plate. A monthly quantity of normal nail plate should be produced by a given subject after the administration of an effective dose of the antifungal ...

    Also Ranks for: Ketoconazole Griseofulvin |  nail plate |  clinical experience |  monthly intervals |  foot dermatoses
    KOL Index score: 7290

    BACKGROUND: Patients with tinea pedis often discontinue treatment before eradication of the fungus when their symptoms improve. The result is an incomplete cure/recurrence.

    OBJECTIVE: Terbinafine, a topical fungicidal agent, was evaluated in double-blind, placebo-controlled trials (159 patients) for its ability to achieve cure and relief of symptoms in the same time frame, that is, before compliance wanes.

    METHODS: Mycologic characteristics (with potassium hydroxide examination and ...

    Also Ranks for: Interdigital Tinea Pedis |  terbinafine 1 |  multicenter trials |  patients vehicle |  5 weeks
    KOL Index score: 7010

    BACKGROUND: Onychomycosis is an increasing problem with limited therapeutic options.

    OBJECTIVE: We evaluated the safety and efficacy, of oral terbinafine, a new fungicidal antimycotic, in patients with toenail onychomycosis.

    METHODS: A North American multicenter, double-blind, placebo-controlled study evaluated the mycologic and clinical efficacy of oral terbinafine 250 mg/day for 12 or 24 weeks in 358 patients with toenail onychomycosis.

    RESULTS: A total of 74% of patients treated with ...

    Also Ranks for: Oral Terbinafine |  toenail onychomycosis |  12 24 weeks |  effective therapy |  antifungal agents
    KOL Index score: 6897

    In separate multicentre, randomized, double-blind clinical trials, 1% ciclopirox olamine cream was compared with its cream vehicle and with 1% clotrimazole cream as treatment for tinea corporis and tinea cruris. Patients who demonstrated clinical and mycological findings consistent with the diagnoses of tinea corporis or tinea cruris were included in the study. Clinical and mycological evaluations were made pretreatment, at the end of each of the four weeks of treatment, and weekly for ...

    Also Ranks for: Tinea Cruris |  ciclopirox olamine cream |  publication administration |  1 treatment |  clinical mycological
    KOL Index score: 6557

    BACKGROUND: The standard treatment of Trichophyton rubrum nail bed onychomycosis (or distal subungual onychomycosis [DSO]) with daily terbinafine for 12 weeks involves treating for a fixed period shorter than the time required for complete replacement of the nail bed and overlying nail plate by normal growth. The same total amount of terbinafine pulse-dosed for approximately 12 months would treat the patient until normal replacement of the mycotic nail bed has occurred.

    OBJECTIVES: To ...

    Also Ranks for: Nail Bed |  terbinafine treatment |  trichophyton rubrum |  drug severity |  distal subungual
    KOL Index score: 5070

    BACKGROUND: Onychomycosis is the most frequent cause of nail disease and represents 30% of all mycotic infections of the skin.

    OBJECTIVE: Our purpose was to compare the effectiveness and tolerability of intermittent dosing of itraconazole ("pulse therapy") with placebo in fingernail onychomycosis.

    METHODS: Seventy-three patients with clinically and mycologically diagnosed fingernail onychomycosis were randomly selected to receive itraconazole, 200 mg twice daily, or placebo for the first ...

    Also Ranks for: Intermittent Therapy |  itraconazole treatment |  46 patients |  aged onychomycosis |  nail disease
    KOL Index score: 4242

    The nail anlage appears in fingers of embryos 9 weeks old.Externally the earliest recognizable nail structure is the primary nail field which is present in embryos at 10 weeks.The first nail structure to keratinize is the distal ridge and is seen in embryos as early as 11 weeks.The earliest matrix was found in the area of the lunula in embryos of 13 weeks.Differentiation of the matrix primordium cells into matrix cells occurs in a distal to proximal direction beginning from the lunula. ...

    Also Ranks for: Nail Plate |  matrix cells |  stratum corneum
    KOL Index score: 4219

    One hundred and eighty three abnormal toe nails were cultured for dermatophytes, molds, and yeasts. Incidence figures for all above mentioned organisms were obtained. In approximately 25% of the abnormal toe nails, dermatophytes were isolated. Trichophyton rubrum and T. mentagrophytes were equally isolated. In approximately 25% of abnormal nails, no organisms were isolated. Non-dermatophytic fungi were commonly associated with abnormal nails (50%). Among these were: Arthroderma ...

    Also Ranks for: Toe Nails |  trichophyton rubrum |  candida parapsilosis |  aspergillus sydowii |  yeasts isolated
    KOL Index score: 4218

    BACTERIA of the Mima-Herellea group were not recognized as distinct and remained undescribed until 1942, when De Bord1 suggested the name Mimeae for a new tribe of gram-negative, nonmotile organisms which resembled Neisseria morphologically, but differed in biochemical characteristics. He named the two new organisms Mima polymorpha and Herellea vaginicola.During subsequent years, other authors reported similar organisms but gave them different names so that the situation became extremely ...

    Also Ranks for: Human Skin |  mima polymorpha |  herellea vaginicola |  biochemical characteristics |  organisms names
    KOL Index score: 4168

    The clinical signs of lichen planus of the nails are reviewed. The inflammatory process of lichen planus may involve any or all of the four nail components; however, it may result in scarring of only the matrix with consequent obliteration of the correspondingly produced portions of the nail plate. Depending on the size of the lesion, intensity of inflammation, and scar produced, the nail plate changes may be permanent or temporary.Characteristically, one sees: (1) irregular, ...

    Also Ranks for: Lichen Planus |  nail plate |  differential female humans |  skin diseases |  pterygium formation
    KOL Index score: 3918

    The systemic treatment of superficial fungus infections in man at last seems a near reality. Although the polyene antibiotics derived from streptomyces were a significant advance in antifungal chemotherapy against the yeast-like fungi, they failed to influence the common dermatomycoses.1 Recent studies demonstrating the influence of serum factors in superficial fungous infections illustrated the importance of blood-borne substances in confining cutaneous invasion by dermatophytes.2,15 ...

    Also Ranks for: Orally Administered Griseofulvin |  skin diseases |  preliminary report |  guinea pigs |  systemic treatment
    KOL Index score: 3846

    Disability from skin diseases among American troops in Vietnam engaged in combat in warm wet areas is often the greatest medical cause of noneffectiveness. Infections are the leading causes of cutaneous disease.The most common infection is produced by a griseofulvin-sensitive elastase producing Trichophyton mentagrophytes but other dermatophytes and Candida albicans are also frequent.Modern treatment has reduced medical evacuation in comparison with World War II. The statistics give ...

    Also Ranks for: Trichophyton Mentagrophytes |  skin diseases |  griseofulvin humans |  candida albicans |  military medicine


    Nardo Zaias: Influence Statistics

    Sample of concepts for which Nardo Zaias is among the top experts in the world.
    Concept World rank
    nb keratosis #1
    abnormal toe nails #1
    extended hyponychium #1
    plantar arch sides #1
    fingernail onycholysis #1
    trichophyton chronic #1
    outbreak dermatitis #1
    toe nails #1
    nails organisms #1
    drug effectiveness onychomycosis #1
    disease humans trichophyton #1
    scopulariopsis brevicalis #1
    painful fingertips fingers #1
    ofthe references #1
    white band site #1
    trichophyton griseofulvin #1
    daily terbinafine #1
    onychomycosis thiabendazole #1
    lesions experimental patients #1
    overlying nail #1
    longitudinal nail biopsy #1
    pityriasis versicolor ketoconazole #1
    effective treatment dso #1
    hippelates flies #1
    names investigator #1
    miami medicine #1
    onychomycosis trials ketoconazole #1
    publication candidiasis medlar #1
    nonfluorescent tinea #1
    naphthalenes ointments #1
    subject mycetoma #1
    griseofulvin hand #1
    question trichophyton #1
    arthrodermataceae foot #1
    illness terbinafine treatment #1
    cutaneous candidiasis dermatophytosis #1
    monthly blood counts #1
    125 terbinafine #1
    etiologic agent species #1

    Key People For Tinea Pedis

    Top KOLs in the world
    Boni Elizabeth Elewski
    tinea capitis nail psoriasis seborrheic dermatitis
    Aditya Kumar Gupta
    tinea capitis seborrheic dermatitis antifungal agents
    Richard C Summerbell
    tinea capitis malassezia species trichophyton rubrum
    Nardo Zaias
    tinea pedis oral terbinafine nail bed
    Roderick James Hay
    global burden skin disease tinea capitis
    James Joseph Leyden
    acne vulgaris benzoyl peroxide staphylococcus aureus

    Nardo Zaias:Expert Impact

    Concepts for whichNardo Zaiashas direct influence:Tinea pedis,  Tinea cruris,  Pemphigus vulgaris,  Oral terbinafine,  Nail bed,  Tinea corporis,  Interdigital tinea pedis,  Cutaneous candidiasis.

    Nardo Zaias:KOL impact

    Concepts related to the work of other authors for whichfor which Nardo Zaias has influence:Tinea pedis,  Lichen planus,  Antifungal agents,  Toenail onychomycosis,  Fungal infections,  Trichophyton rubrum,  Nail psoriasis.



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    Division of Dermatology, Greater Miami Skin and Laser Center, Miami Beach, FL; nardozaias@aol.com. | Dermatology Mt. Sinai Medical Center Miami Beach FL USA | Dermatology division, Greater Miami Skin and Laser, Mount Sinai Medical Center, Miami Beach