• Disease
  • Graves
  • Graves Ophthalmopathy
  • James A Garrity

    Prominent publications by James A Garrity

    KOL Index score: 12993

    OBJECTIVE: To evaluate the safety and efficacy of stereotactic radiosurgery, either with or without transarterial embolization, in the treatment of patients with dural arteriovenous fistulae (DAVFs) of the cavernous sinus.

    METHODS: We reviewed the findings, from a prospectively established database, for 20 patients with cavernous sinus DAVFs who were treated with either radiosurgery alone (n = 7) or radiosurgery and transarterial embolization (n = 13) in a 7-year period. The median ...

    Also Ranks for: Cavernous Sinus |  stereotactic radiosurgery |  patients davfs |  transarterial embolization |  dural arteriovenous fistulae
    KOL Index score: 12059

    PurposeAdenoid cystic carcinoma (ACC) represents ~10–15% of salivary neoplasms and almost universally exhibits a lethal clinical course. ACC is also known to occur in the lacrimal gland. ACC is characterized by its heterogeneous morphology and may demonstrate tubular, cribriform, and/or solid architectural patterns. Unfortunately, these histopathological features are not specific to ACC and can be seen in other salivary gland-type neoplasms, introducing a diagnostic dilemma. The ...

    Also Ranks for: Lacrimal Gland |  myb rearrangement |  cystic carcinoma |  situ hybridization |  neoplasms female
    KOL Index score: 11006

    PURPOSE: To determine the potential suitability of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) for measuring health-related quality of life (HRQL) in patients with Graves' ophthalmopathy.

    DESIGN: Cross-sectional study.

    PARTICIPANTS: Thirty adult patients with mild to severe Graves' ophthalmopathy.

    METHODS: Participants self-administered the NEI VFQ-25 and completed a semistructured interview to provide feedback about the questionnaire. The percentage of ...

    Also Ranks for: Graves Ophthalmopathy |  ceiling effects |  vfq25 scores |  visual function |  composite score
    KOL Index score: 9812

    PURPOSE: To determine the clinical characteristics of an incidence cohort of patients with Graves' ophthalmopathy.

    METHODS: We reviewed the community medical records of 120 patients residing in Olmsted County, Minnesota, in whom Graves' ophthalmopathy was diagnosed between 1976 and 1990.

    RESULTS: Among 120 patients with Graves' ophthalmopathy, 108 (90%) patients had Graves' hyperthyroidism, one (1%) had primary hypothyroidism, four (3%) had Hashimoto's thyroiditis, and seven (6%) were ...

    Also Ranks for: Incidence Cohort |  patients graves ophthalmopathy |  eyelid retraction |  time diagnosis |  graves hyperthyroidism
    KOL Index score: 9375

    Orbital involvement at the time of initial presentation is unusual in non-Hodgkin's lymphoma. In an effort to identify potential ways of improving the radiotherapeutic management of this disease, the records of 22 patients were reviewed retrospectively. All had biopsy-proven orbital non-Hodgkin's lymphoma, and the minimal, median, and maximal durations of follow-up in surviving patients were 4.8 years, 7.0 years, and 17.4 years, respectively. Permanent local control was achieved in 21 of ...

    Also Ranks for: Radiation Therapy |  local control |  10 years |  primary orbital |  22 patients
    KOL Index score: 9315

    Granulomatosis with polyangiitis (GPA) (Wegener's) may mimic IgG4-related disease (IgG4-RD) on histologic examination of some biopsies, especially those from head and neck sites. IgG4 immunostaining is often performed in this context for differential diagnosis with IgG4-RD. Herein, we report the results of IgG4-positive (IgG4+) cells in 43 cases of GPA including 26 previously published cases as well as the newly added cases from the lung and kidney. We also included 20 control cases ...

    Also Ranks for: Polyangiitis Gpa |  plasma cells |  differential diagnosis |  highpower field |  control cases
    KOL Index score: 9151

    OBJECTIVE: To describe clinical, radiographic, and morphologic findings in patients with IgG4-positive cells present on orbital biopsy specimens.

    DESIGN: Retrospective review (from January 1, 1993, through December 31, 2006) of patients with orbital biopsy specimens that excluded lymphoma; comparison of patients with and without IgG4-positive cells on immunostaining.

    RESULTS: Of 21 patients, 11 had increased IgG4-positive cells (defined as >10 cells on biopsy). Symptoms included eyelid ...

    Also Ranks for: Plasma Cells |  systemic disease |  orbital inflammation |  patients igg4 |  lymphoid hyperplasia
    KOL Index score: 8345

    PURPOSE: To determine the chronologic characteristics of Graves' ophthalmopathy in an incidence cohort of 120 patients.

    METHODS: We reviewed the community medical records of 120 patients residing in Olmsted County, Minnesota, in whom Graves' ophthalmopathy had been diagnosed between 1976 and 1990.

    RESULTS: Median age at the time of diagnosis of Graves' ophthalmopathy was 43 years; the minimum and maximum ages were 8 and 88 years, respectively. Among 108 patients with hyperthyroidism, ...

    Also Ranks for: Graves Ophthalmopathy |  thyroid dysfunction |  olmsted county |  20 patients |  iodine radioisotopes
    KOL Index score: 8222

    Visual loss (acuity or field) secondary to ischemic optic neuropathy (ION) is a rare but devastating complication of cardiac surgery involving cardiopulmonary bypass (CPB). We determined clinical features and risk factors for ION by a retrospective time-matched, case-control study. ION was identified in 17 (0.06%) patients out of 27,915 patients who underwent CPB between January 1, 1976, and December 31, 1994. For each ION patient, two patients who underwent CPB exactly 2 wk before the ...

    Also Ranks for: Cardiopulmonary Bypass |  ischemic optic |  cardiac surgery |  patients cpb |  neuropathy ion
    KOL Index score: 8118

    CONTEXT: Graves' orbitopathy (GO) is a potentially sight-threatening disease for which available medical therapy is not uniformly successful. Multiple case series suggest that rituximab (RTX) may be effective therapy for GO patients.

    OBJECTIVE: To determine the efficacy of RTX in GO.

    DESIGN: It is a prospective, randomized, double-masked, placebo-controlled trial.

    SETTING: The study was conducted at a large academic private practice.

    PATIENTS: Twenty five patients with active moderate to ...

    Also Ranks for: 24 Weeks |  rituximab patients |  graves orbitopathy |  antibodies monoclonal |  randomized controlled
    KOL Index score: 7837

    PURPOSE: Transantral orbital decompression is effective treatment for excessive proptosis and optic neuropathy due to Graves ophthalmopathy. In these sight-threatening circumstances, patients willingly accept the side effects of orbital decompression. When transantral orbital decompression is performed for cosmetic indications, patients' acceptance of side effects may be different. This study reports detailed results of transantral decompression for 34 patients in whom the indications ...

    Also Ranks for: Graves Ophthalmopathy |  orbital decompression |  followup questionnaire |  patients diplopia |  medical records
    KOL Index score: 7726

    OBJECT: Ventriculoperitoneal (VP) shunts have not been widely used for idiopathic intracranial hypertension (IIH) because of the difficulty of placing a shunt into normal or small-sized ventricles. The authors report their experience with stereotactic placement of VP shunts for IIH.

    METHODS: The authors reviewed the clinical records of all patients in whom stereotaxis was used to guide the placement of a VP shunt for IIH at their institution. All shunts were placed using stereotactic ...

    Also Ranks for: Intracranial Hypertension |  ventriculoperitoneal shunt |  refractory idiopathic |  stereotactic placement |  retrospective studies
    KOL Index score: 7428

    Visual dysfunction developing in association with acquired immunodeficiency syndrome (AIDS) can be multifactorial. Two patients with this syndrome and cryptococcal meningitis had papilledema and visual loss. Both were treated by optic nerve sheath fenestration. One patient had bilateral nonsimultaneous optic nerve sheath fenestrations; visual function improved in one eye. The other patient had bilateral visual improvement after a unilateral optic nerve sheath fenestration. Cryptococcal ...

    Also Ranks for: Cryptococcal Meningitis |  optic nerve |  visual loss |  aids patients |  immunodeficiency syndrome
    KOL Index score: 7322

    PURPOSE: To determine the clinical characteristics and outcomes of patients with leukemic or lymphomatous involvement of the lacrimal drainage system (LDS).

    METHODS: A computerized retrieval system was used to identify patients with histologically proven leukemic or lymphomatous involvement of the LDS. Medical records were reviewed.

    RESULTS: Biopsies of the lacrimal sac or nasolacrimal duct obtained during dacryocystorhinostomies (DCR) performed at the Mayo Clinic (Rochester, Minnesota) ...

    Also Ranks for: Lacrimal Drainage |  cell lymphoma |  antineoplastic agents |  systemic disease |  lymphocytic chronic
    KOL Index score: 7322

    BACKGROUND AND PURPOSE: Orbital non-Hodgkin's lymphomas (NHL) have traditionally been treated with radiation. Forty-eight patients presenting with orbital NHL were treated with radiation and were evaluated for local control, overall survival, cause-specific survival, and complications.

    MATERIALS AND METHODS: Forty-five patients had low-grade and 3 patients had intermediate-grade histologic findings. Orbit-only disease occurred in 22 patients, the conjunctiva in 16, both in five, and ...

    Also Ranks for: Orbital Lymphoma |  radiation doses |  local control |  specific survival |  complications patients


    James A Garrity: Influence Statistics

    Sample of concepts for which James A Garrity is among the top experts in the world.
    Concept World rank
    followup neurofibromatosis #1
    proptosis visual #1
    local anesthesia diagnosis #1
    painless diplopia #1
    initial database screening #1
    501342 anesthetics #1
    lymphocytic components ioi #1
    cases common subtypes #1
    development diplopia #1
    proptosis 58 #1
    clinically distensible lesions #1
    labyrynthine challenge #1
    gpa igg4 #1
    7 13 biopsies #1
    proptosis visual field #1
    bulk retrobulbar tissues #1
    vertical misalignment patients #1
    radiation graves #1
    410189 patients #1
    decompression orbital fat #1
    water binding molecules #1
    surgical young adult #1
    swollen tissues space #1
    secondary graves #1
    faint vessels #1
    inflammatory orbital pseudotumor #1
    unkown etiology #1
    commonly orbital #1
    orbital lipectomy #1
    13 orbital biopsies #1
    wegeners granutomatosis #1
    paradoxical weak tool #1
    vfq25 healthrelated quality #1
    poignant cases #1
    confined retrobulbar space #1
    clinical exam characteristics #1
    longer 30 #1
    lipectomy orbit tomography #1
    presentation ted #1
    flow arterialized #1
    orbital biopsies #1

    Key People For Graves Ophthalmopathy

    Top KOLs in the world
    Wilmar Maarten Wiersinga
    graves ophthalmopathy thyroid hormone fatty acids
    Rebecca S Bahn
    graves ophthalmopathy thyrotropin receptor thyroid association
    Luigi BARTALENA,
    graves disease orbital radiotherapy radioiodine therapy
    Maarten Ph Mourits
    graves orbitopathy intraocular lens strabismus surgery
    Claudio Marcocci
    primary hyperparathyroidism graves orbitopathy orbital radiotherapy
    Mark F Prummel
    graves ophthalmopathy orbital tissue tsh receptor

    James A Garrity:Expert Impact

    Concepts for whichJames A Garrityhas direct influence:Graves ophthalmopathy,  Optic nerve,  Incidence cohort,  Orbital decompression,  Surgical management,  Graves disease,  Postoperative diplopia,  Orbital inflammation.

    James A Garrity:KOL impact

    Concepts related to the work of other authors for whichfor which James A Garrity has influence:Thyroid eye disease,  Graves ophthalmopathy,  Orbital decompression,  Optic nerve,  Visual loss,  Lacrimal gland,  Radiation therapy.



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    Mayo Clinic, Rochester, MN, USA | Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota. | Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA. | Mayo Clinic, Department of Ophthalmology, 200 1st St. SW, Rochester, MN, USA. |