Matthew Morris

Matthew Morris

Department Of Chemistry And Biochemistry, Miami University, Oxford, Ohio, 45056, United States

Direct Impact

Concepts for which Matthew Morris has direct influence:

overcome zinc scarcity
delhi metallo
penam turnover
selective pressure
antibiotic structure
infection sites
bioinorganic spectroscopy

Prominent publications by Matthew Morris

KOL-Index: 12 Use and misuse of antibiotics have driven the evolution of serine β-lactamases to better recognize new generations of β-lactam drugs, but the selective pressures driving evolution of metallo-β-lactamases are less clear. Here, we present evidence that New Delhi metallo-β-lactamase (NDM) is evolving to overcome the selective pressure of zinc(II) scarcity. Studies of NDM-1, NDM-4 (M154L), and ...
Known for
Β-Lactam Drugs | Evolution Metallo | Misuse | X-Ray Crystallography

Department of Chemistry and Biochemistry, Miami University, Oxford, Ohio, 45056, United States

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