Jan C Schmolling: Influence Statistics

Jan C Schmolling

Jan C Schmolling

Krankenhaus der Augustinerinnen, Gynecology and Maternity Clinic, Jakobstraße 27-31, 50678 Cologne, Germany. | Krankenhaus der Augustinerinnen, Gynecology and maternity ...

Jan C Schmolling: Expert Impact

Concepts for which Jan C Schmolling has direct influence: Antiidiotypic antibodies , Oxytocin receptor , Maternal serum , Ovarian carcinoma , Extracorporeal perfusion , Ovarian cancer , Human uterus .

Jan C Schmolling: KOL impact

Concepts related to the work of other authors for which for which Jan C Schmolling has influence: Ovarian cancer , Preterm labor , Bone metastases , Maternal serum , Oxytocin receptor , Uterine peristalsis , Embryo transfer .

KOL Resume for Jan C Schmolling


Krankenhaus der Augustinerinnen, Gynecology and Maternity Clinic, Jakobstraße 27-31, 50678 Cologne, Germany.


Krankenhaus der Augustinerinnen, Gynecology and maternity clinic, Jakobstraße 27- 31, 50678, Cologne, Germany


Krankenhaus der Augustinerinnen, Gynecology and maternity clinic, Jakobstraße 27-31, 50678, Cologne, Germany


Krankenhaus der Augustinerinnen, Köln


Department of Obstetrics and Gynecology, University of Bonn School of Medicine, Sigmund-Freud-Strasse 25, 53105, Bonn, Germany


Department of Obstetrics and Gynecology, KH der Augustinerinnen, Jakobstrasse 27–31, 50678, Cologne, Germany


Universitäts-Frauenklinik Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany


Department of Obstetrics & Gynecology, University of Bonn School of Medicine, Sigmund Freud Straße 25, D-53105 Bonn, Germany Fax: +49-228-287 5446, DE

Obstetrics and Gynecology


Departments of Obstetrics and Gynecology, *University of Bonn, †University of Tübingen, Tübingen, Germany; ‡Institute of Medical Statistics, University of Bonn, Bonn, Germany


From the Department of Gynecology and Obstetrics, University of Bonn, Bonn, Germany


Department of Gynecology and Obstetrics, University of Bonn, Bonn, Germany

Universitäts-Frauenklinik Bonn.


Universitätsfrauenklinik, Bonn.


Dept. of Gynecology and Obstetrics, University of Bonn, Sigmund Freud Str. 25, 5300, Bonn/Vensuberg, Germany

Prominent publications by Jan C Schmolling

KOL-Index: 12079 . We have generated an immunoglobulin G1 (IgG1) murine monoclonal anti-idiotype antibody (Ab2) designated ACA125, which mimics a specific epitope on the tumor-associated antigen CA125. This antigen is expressed by most of malignant ovarian tumors. Patients with CA125-positive tumors are immunologically tolerant to CA125. We used ACA125 as a surrogate for the tumor-associated antigen CA125 ...
Known for Ovarian Cancer | Immunological Responses | Ca125 Antigen | Anti Idiotype
KOL-Index: 7450 . Abstract This study documents values of biochemical markers of bone remodeling in 106 patients with breast cancer. Based on scintigraphic and radiological findings, patients were divided into 3 groups: 19 patients with bone metastases, 65 patients without bone metastases and normal bone scintigrams, and 22 patients with pathological, non-malignant findings on scintigraphy without proof of ...
Known for Breast Cancer | Bone Metastases | Collagen Type | Biochemical Markers
KOL-Index: 6778 . Immunotherapy with monoclonal antibodies has become a hopeful approach to the adjuvant therapy of cancer patients. Recently, formation of antiidiotypic antibodies (Ab2) has been demonstrated in ovarian cancer patients after immunization with F(ab')2 fragments of the monoclonal antibody OC 125 (MAb OC 125). Preliminary results suggested that patients with high Ab2 serum concentrations had ...
Known for Antiidiotypic Antibodies | Monoclonal Antibody | Ovarian Cancer | Mab B723
KOL-Index: 6456 . Clinical observations suggest that flecainide might pass the placenta more easily than digoxin, and that its transfer is less disturbed in case of hydrops fetalis than that of digoxin. The purpose of the study was to compare the materno-fetal transplacental transfer of digoxin, flecainide, and amiodarone, another antiarrhythmic agent used in the treatment of fetal tachyarrhythmia, and to ...
Known for Transplacental Transfer | Placenta Pregnancy | Tachycardia Supraventricular | Fetal Diseases
KOL-Index: 5989 . IntroductionIn the pregnant uterus oxytocin and the oxytocin receptor play a major part for uterine contractility and the induction of labor. Clinical evidence implicates that with regard to contractility associated disorders like for example dysmenorrhea also in the nonpregnant and very early pregnant myometrium oxytocin and the oxytocin receptor seem to be more important than believed at ...
Known for Oxytocin Receptor | Nonpregnant Uterus | Uterine Contractility | Extracorporeally Perfused
KOL-Index: 5687 . ObjectiveAtosiban has been shown to be an effective tocolytic agent with a low rate of side effects during 24 to 33 weeks of gestation. Atosiban acts through selective, competitive inhibition of both oxytocin and vasopressin, so that there are reasons to assume that a tocolytic effect can also be achieved earlier in the pregnancy.Study designIn this prospective, randomized pilot study, 20 ...
Known for Obstetric Labor | Gestation Atosiban | Oxytocin Tocolytic | Pregnancy Outcome
KOL-Index: 4847 . BackgroundThe aim of the prospective study was to compare standard parameters as Doppler ultrasound and 24-h blood pressure measurement with possible maternal serological markers regarding their prognostic value in predicting hypertensive diseases in pregnancy.MaterialsTwenty-four-hour blood pressure measurement was performed before and after 32+0 gestational week in 57 pregnant women with ...
Known for Adhesion Molecules | Blood Pressure | Hypertension Pregnancy | Women Preeclampsia
KOL-Index: 4581 . Oxytocin (OT) and the oxytocin receptor (OTR) seem to be less important for uterine contractility-associated disorders of the non-pregnant uterus compared to the pregnant uterus. In the present study, we investigated the mutual dependence of OTR, OT and 17beta-estradiol (E(2)) with regard to the localization of OTR in the non-pregnant uterus. Utilizing our established model for ...
Known for Oxytocin Receptor | Human Myometrium | Otr Expression | Nonpregnant Uterus
KOL-Index: 4408 . Recorded concentrations of the tumour-associated glycoprotein 72 (TAG-72) in ovarian cancer patients after repeated infusion of the antibody B72.3 were found to be falsely elevated when measured with an homologous immunometric assay involving the anti-TAG-72 antibody B72.3 (Test 1), or with an heterologous assay involving CC49 capture and B72.3 detector antibodies (Test 2). Test 1 yielded ...
Known for Idiotypic Antibodies | Human Anti | Glycoprotein 72 | Ovarian Cancer Patients
KOL-Index: 3443 . The aim of this study was to evaluate the influence of different maternal and fetal albumin concentrations on the transplacental transfer and the placental tissue accumulation of digoxin. Digoxin passage across the isolated lobules of 15 human placentae was calculated from repeated fetal and maternal perfusate samples, and placental tissue digoxin concentrations were measured at the end of ...
Known for Albumin Concentrations | Fetal Maternal | Placenta Pregnancy | Anti Arrhythmia
KOL-Index: 3199 . Experimental perfusion of various organs has primarily been used in transplantation medicine to study the physiology, pathophysiology and metabolism of tissues and cells. The purpose of this study was to establish an experimental model for the extracorporeal perfusion of the human uterus with recirculation of a modified, oxygenated Krebs-Henselait solution, in comparison with a ...
Known for Experimental Model | Extracorporeal Perfusion | Human Uterus | Lactate Dehydrogenase
KOL-Index: 2994 . An immunoradiometric assay is described for the determination of human anti-idiotypic anti-B72.3 IgG. The latter is formed in ovarian cancer patients after treatment with the murine monoclonal antibody B72.3, which is directed against the tumour-associated glycoprotein 72 (TAG-72). A gel coupled with Fc-specific anti-human IgG antibodies is used as a solid phase for the extraction of serum ...
Known for Antibodies Anti | Cross Reactions | Ovarian Neoplasms | Glycoproteins Humans
KOL-Index: 2861 . Neonaticide is a serious allegation that needs a complete chain of criminal investigations. In this context, a nuchal cord is considered to be responsible for an infant’s death, but there is a clear lack of evidence. The purpose of our study is to reveal if a nuchal cord can be responsible for stillbirth, poor perinatal outcome, or neonatal death in the forensic aspect. We conducted a ...
Known for Nuchal Cord | Newborn Intensive Units | Apgar Score | Adverse Perinatal
KOL-Index: 2576 . Based on the network theory, anti-tumor antibodies (Ab1) can trigger the immune system of the host into a response against tumor cells. Through an immunological cascade, anti-idiotypic antibodies bearing the internal image of epitopes of the nominal antigen (Ab2 beta) are produced that themselves can induce cellular and humoral cytotoxic effects against the antigen-expressing tumor cell. ...
Known for Ovarian Carcinoma | Antibodies Anti | Tumor Cells | Induce Humoral

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Krankenhaus der Augustinerinnen, Gynecology and Maternity Clinic, Jakobstraße 27-31, 50678 Cologne, Germany. | Krankenhaus der Augustinerinnen, Gynecology and maternity clinic, Jakobstraße 27- 31, 50678, Cologne, Germany | Krankenhaus der Augustineri