• Disease
  • Pancreatic
  • Pancreatic Cancer
  • Bo Bo Yang

    Prominent publications by Bo Bo Yang

    KOL Index score: 17999

    BACKGROUND: The effect of the α-glucosidase inhibitor acarbose on cardiovascular outcomes in patients with coronary heart disease and impaired glucose tolerance is unknown. We aimed to assess whether acarbose could reduce the frequency of cardiovascular events in Chinese patients with established coronary heart disease and impaired glucose tolerance, and whether the incidence of type 2 diabetes could be reduced.

    METHODS: The Acarbose Cardiovascular Evaluation (ACE) trial was a ...

    Also Ranks for: Impaired Glucose Tolerance |  coronary heart disease |  cardiovascular death |  chinese patients |  diabetes outcomes
    KOL Index score: 15791

    Kisspeptin, the product of Kiss1 gene, is a novel regulator of the gonadotropic axis. In mammals, its stimulatory effect on gonadotropin secretion is well documented and mediated mainly by hypothalamic release of gonadotropin-releasing hormone. Although the pituitary actions of kisspeptin have been reported, the effects of kisspeptin on gonadotropin release via direct action on pituitary cells are still controversial. Using goldfish as a model, here we examined the direct actions of ...

    Also Ranks for: Gene Expression |  growth hormone |  pituitary level |  molecular cloning |  goldfish kisspeptin
    KOL Index score: 15595

    BACKGROUND: In late December, 2019, patients presenting with viral pneumonia due to an unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was subsequently identified as the causative pathogen, provisionally named 2019 novel coronavirus (2019-nCoV). As of Jan 26, 2020, more than 2000 cases of 2019-nCoV infection have been confirmed, most of which involved people living in or visiting Wuhan, and human-to-human transmission has been confirmed.

    METHODS: We did ...

    Also Ranks for: Virus Humans |  viral receptors |  receptor binding |  phylogenetic analysis |  2019 ncov
    KOL Index score: 14783

    The CXCL12-CXCR4 chemokine axis may play a very important role in ovarian cancer cells proliferation, migration, invasion, and peritoneal metastasis in vitro and in vivo. In this study, transfected SKOV3-CXCR4, transfected vector SKOV3-negative, nontransfected SKOV3 ovarian cancer cells, and human peritoneal mesothelial cells (HPMCs) were cultivated in vitro, and the proliferation, migration, and invasion of these ovarian cancer cells were investigated with or without the influence of ...

    Also Ranks for: Ovarian Cancer |  cxcr4 axis |  migration invasion |  cell proliferation |  inbred balb mice
    KOL Index score: 13560

    BACKGROUND: The initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP.

    METHODS: We collected information on demographic characteristics, exposure history, and illness timelines of laboratory-confirmed cases of NCIP that had been reported by January 22, 2020. We described ...

    Also Ranks for: Early Transmission Dynamics |  confirmed cases wuhan |  basic reproductive |  china december |  demographic characteristics
    KOL Index score: 13513

    According to recent studies, long non-coding RNA X-inactive specific transcript (XIST) is involved in the development and progression of many malignant tumors including pancreatic cancer. We validated the detailed role of XIST in human pancreatic cancer (PC) cell lines and PC tissues so as to determine its exact function and the mechanism by which it affected PC proliferation. In our research, lncRNA-XIST was specifically upregulated in PC tissues and cell lines, and high XIST expression ...

    Also Ranks for: Xist Mir133a |  pancreatic cancer |  long noncoding rna |  cell proliferation |  expression regulation
    KOL Index score: 13191

    The highly expressed Id1 (inhibitor of DNA binding/differentiation) protein promotes angiogenesis in HCC and is a well established target for anti-angiogenesis therapeutic strategies. Heparan sulfate (HS) mimetics such as PI-88 can abrogate HS-protein interactions to inhibit angiogenesis. Id1 is the direct downstream effector of bone morphogenetic proteins (BMPs), which are angiogenic and HS-binding proteins. Thus, targeting BMPs by HS mimetics may inhibit angiogenesis via attenuating ...

    Also Ranks for: Nude Mice |  bone morphogenetic |  hmec1 cells |  tube formation |  id1 signaling
    KOL Index score: 12941

    T helper17 (Th17) cells have been demonstrated to participate in the pathogenesis of hepatitis B virus (HBV) associated liver damage. However, the contribution of Th17 cells to immune activation and disease aggravation in patients with HBV infection is not fully clear. In this study, we investigated the Th17 cells frequencies and interleukin-17 (IL-17) mRNA expressions in peripheral blood mononuclear cells (PBMCs), intrahepatic IL-17-positive cells accumulation, as well as serum IL-17 ...

    Also Ranks for: Th17 Cells |  disease aggravation |  immune activation |  chronic hepatitis |  liver failure
    KOL Index score: 12935

    The embryonic stem cell self-renewal gene, Nanog, has been shown to be expressed in several tumor types and to regulate tumor development. The aim of this study was to carry out a detailed analysis of Nanog expression in human endometrial adenocarcinoma (EAC). Immunohistochemical analysis and reverse transcription-polymerase chain reaction were used to characterize Nanog, Sox2, and Oct4 expression in tissue arrays containing EAC, benign endometrium samples, and tumorosphere cells. ...

    Also Ranks for: Stem Cell |  expression nanog |  sox2 oct4 |  eac samples |  human endometrial
    KOL Index score: 12781

    Geometric moment invariants are widely used in many fields of image analysis and pattern recognition since their first introduction by Hu in 1962. A few years ago, Flusser has proved how to find the independent and complete set of geometric moment invariants corresponding to a given order. On the other hand, the properties of orthogonal moments show that they can be recognized as useful tools for image representation and reconstruction. Therefore, derivation of invariants from orthogonal ...

    Also Ranks for: Hermite Moments |  translation invariants |  gaussian – |  pattern recognition |  image analysis
    KOL Index score: 12376

    Growth factors such as brain-derived neurotrophic factor (BDNF) are widely used in the recovery of spinal cord injury (SCI) for promoting axonal regeneration or improving neuron survival. However, the lack of efficient delivery approaches limits their clinical applications. In this study, we constructed an efficient delivery system including collagen-binding BDNF and linear ordered collagen scaffolds (LOCS). A collagen-binding domain (CBD) was utilized to construct collagen-targeting ...

    Also Ranks for: Collagen Scaffolds |  neurotrophic factor |  spinal cord injury |  binding brain |  cbd bdnf
    KOL Index score: 12241

    AIMS: To describe the prevalence and associations of epiretinal membrane (ERM) in an elderly urban Chinese population in China.

    METHODS: A population-based cross-sectional study was conducted using a cluster random sample of residents aged 50 years or older living in the Jiangning Road Sub-district, Shanghai, China. All participants underwent a standardised interview and comprehensive eye examinations, including digital retinal photography and spectral domain optical coherence tomography ...

    Also Ranks for: Epiretinal Membrane |  prevalence erm |  cmr pmf |  eye study |  chinese population
    KOL Index score: 12215

    AIM: To investigate the effects of inhibiting factor of cell cycle regulation p57(kip2), retinoblastinoma protein (Rb protein) and proliferating cell nuclear antigen (PCNA) in the genesis and progression of human pancreatic cancer.

    METHODS: The expression of p57(kip2), Rb protein and PCNA in tumor tissues and adjacent tissues of 32 patients with pancreatic cancer was detected with SP immunohistochemical technique.

    RESULTS: p57(kip2) protein positive-expression rate in tumor tissues of ...

    Also Ranks for: Pancreatic Cancer |  expression p57kip2 |  tumor tissues |  p005 pcna |  cell nuclear
    KOL Index score: 11454

    The effect of β-aminobutyric acid (BABA) on control of anthracnose caused by Colletotrichum gloeosporioides in mango fruit and its possible mechanisms were investigated. The results show that BABA treatments effectively suppressed the expansion of lesion in mango fruit inoculated with C. gloeosporioides during storage at 25°C, with the greatest efficacy being obtained using 100mM BABA. However, BABA at 25–400mM did not exhibit direct antifungal activity against C. gloeosporioides in ...

    Also Ranks for: Mango Fruit |  colletotrichum gloeosporioides |  baba treatment |  aminobutyric acid |  anthracnose caused
    KOL Index score: 11336

    Osteoarthritis (OA) is a degenerative injury of the articular cartilage and reactive hyperplasia of the articular rim and subchondral bone. Due to its poor prognosis, this study is to research the influences of lncRNA HOTAIR on synovial inflammation and synoviocyte apoptosis and proliferation in OA rats by regulating the Wnt/β-catenin pathway. Rat OA model was constructed by means of cruciate ligament resection, and the successfully modeled rats were injected with sh-HOTAIR, or ...

    Also Ranks for: Synovial Inflammation |  proliferation apoptosis |  catenin signaling |  long noncoding rna |  wnt β


    Bo Bo Yang: Influence Statistics

    Sample of concepts for which Bo Bo Yang is among the top experts in the world.
    Concept World rank
    proposed peh cse #1
    stan11 #1
    applications smart‐phone #1
    outcome enrolled patients #1
    stans gene #1
    accuracy aib #1
    balance liver #1
    landscape performance #1
    msc transplantation outcome #1
    timesharing management #1
    inflammation glycolysis #1
    china passive medicine #1
    smart‐phone #1
    aib tcb #1
    city park performance #1
    irradiated tpi #1
    normal weight egfr #1
    hydrographic distributions #1
    orbit geometric calibration #1
    nrf2 pathways cir #1
    p005 pcna #1
    hk2 cells protective #1
    stans transcription factors #1
    desulfurization wastewater dw #1
    review mcharg method #1
    ppyabf3 ppydam3 expression #1
    bach1 gc progression #1
    smart‐phone infrared chip‐spectrometer #1
    new coronary pneumonia #1
    tumour grade sarcomatoid #1
    linc00665 bach1 #1
    tpi radiation dose #1
    chapter ecological wisdom #1
    cases stroke length #1
    pge1 probucol #1
    target cryptosporidium parvum #1
    steel wool fiber #1
    mic water systems #1
    kmsa differences #1
    stan11 anthocyanins #1
    positive solutions method #1
    csf origins #1
    integrated imrt #1
    direct‐writing grayscale #1
    expression ywhaz #1
    spontaneous perforation colon #1
    cost pon #1
    gaussian bracket #1
    gaussian hermite moments #1
    lncrna linc01410 #1

    Key People For Pancreatic Cancer

    Top KOLs in the world
    Ralpha H Hruban†
    pancreatic cancer gene expression tumor carcinoma
    Ahmedin M Jemal
    united states breast cancer addis ababa
    Rebecca L Siegel
    united states colorectal cancer incidence rates
    Anirban Maitra
    pancreatic cancer precursor lesions early detection
    Markus Wolfgang Büchler†
    pancreatic cancer chronic pancreatitis liver transplantation
    Helmut M Friess†
    pancreatic cancer chronic pancreatitis growth factor

    Bo Bo Yang:Expert Impact

    Concepts for whichBo Bo Yanghas direct influence:Pancreatic cancer,  Migrant workers.

    Bo Bo Yang:KOL impact

    Concepts related to the work of other authors for whichfor which Bo Bo Yang has influence:Coronavirus disease covid19,  Clinical characteristics,  Sarscov2 infection,  Spike protein,  Disease 2019,  Acute respiratory,  Healthcare workers.



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    Department of Electrical and Computer Engineering, University of Toronto, ON, M5S 3G4, Canada | Water Science and Environmental Engineering Research Center, College of Chemical and Environmental Engineering, Shenzhen University, Shenzhen 518060, Chin