The mitochondrial and microsomal cytochrome P-450 contents of C57B1/6 mouse testis have been measured using difference spectroscopy on stable enzyme preparations containing the ferrous-carbon monoxide complex. Results were obtained on control animals (52 +/- 3 days of age) and on animals injected subcutaneously with human choriogonadotropin (0.017 micrograms/g body weight 24 h prior to sacrifice). The high ratio of testicular mitochondrial cytochrome oxidase to P-450, which has ...

OBJECTIVE: Clinical T2N0 esophageal carcinoma is a heterogenous disease frequently complicated by inaccurate staging. Incorrect staging may lead to suboptimal treatment for patients with unidentified local-regionally advanced disease. Therapeutic options for these patients remain controversial. We sought to evaluate the outcomes of patients with cT2N0 who underwent esophagectomy as either primary therapy or after neoadjuvant treatment.

METHODS: This was a multi-institutional ...

Pulmonary contusion is a frequent sequelae of blunt chest trauma. If significant shear forces are encountered during energy transfer to the chest wall, pulmonary laceration may result. Most traumatic pulmonary lacerations resolve spontaneously. However, secondary infection of a posttraumatic laceration often leads to serious complications that may be lethal. We report a case of a secondarily infected pulmonary laceration resulting from blunt trauma that was successfully treated by ...