• KOLs
  • Phase Iii
  • John A. Ellerton
John A. Ellerton

John A. Ellerton

From Mountain Rescue (England And Wales), Cumbria, England (Dr Ellerton); The Eye Clinic, University Hospital, Croatian Mountain Rescue Service, Split, Croatia (Dr Zuljan); ...

Direct Impact

Concepts for which John A Ellerton has direct influence:

phase iii
lung cancer
inotuzumab ozogamicin
absence unacceptable
arm receive
brentuximab vedotin
tumor cells

External impact

Concepts related to the work of other authors for which John A Ellerton has influence:

her2-positive metastatic breast cancer
phase iii
oral vinorelbine
hazard ratio
pertuzumab combination
progression-free survival
high-altitude exposure

Prominent publications by John A. Ellerton

KOL-Index: 42 BACKGROUND: CLEOPATRA was a phase 3 study comparing the efficacy and safety of pertuzumab, trastuzumab, and docetaxel with placebo, trastuzumab, and docetaxel in patients with HER2-positive metastatic breast cancer. In the primary analysis and subsequent reports, progression-free and overall survival were significantly improved in the pertuzumab group compared with the placebo group. Here, ...
Known for
95 | Safety | 408 | 396
KOL-Index: 26 A 53-year-old male developed acute erythroleukemia three years after renal transplantation. He had received three years of immunosuppressive therapy with azathioprine. A preleukemia phase associated with chromosome abnormalities was recognized. Azathioprine has been associated with chromosome abnormalities. The chronic stimulation of an abnormal erythroid clone by transplantation may have ...
Known for
53-Year-Old Male Developed Acute | Azathioprine Chromosome | Erythroleukemia Renal
KOL-Index: 10 Although eyes are not frequently injured in the mountains, they are exposed to many adverse factors from the environment. This article, intended for first responders, paramedics, physicians, and mountaineers, is the consensus opinion of the International Commission for Mountain Emergency Medicine (ICAR-MEDCOM). Its aim is to give practical advice on the management of eye problems in ...
Known for
Lenses Eye | Emergency Icar | Loss Sight | Medcom
KOL-Index: 7 In a multicenter, phase II trial, CI-958, a benzothiopyranoindazole DNA intercalator, was administered to 18 patients who had not received prior chemotherapy for metastatic colorectal cancer. The drug was given by intravenous infusion at a dose of 700 mg/m2 every 21 days. There were no objective responses. Grades III and IV toxic effects were limited to granulocytopenia in 42% of courses and ...
Known for
Ci-958 Metastatic | Phase Intravenous
KOL-Index: 2 This phase 3 trial compares the addition of nivolumab to chemotherapy (carboplatin and paclitaxel) versus usual treatment (chemotherapy alone) for the treatment of anal cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor ...
Known for
Unacceptable Toxicity | Repeats Cycles | Arm Receive | Cells Stopping
KOL-Index: 2 This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that have spread to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help ...
Known for
Benefit Rate | Rare Histologies | Immunotherapy Drugs | Tissue Banking
KOL-Index: 2 This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a mutation in a protein called anaplastic lymphoma kinase (ALK). Mutations, or changes, in ALK can make it very active and important for tumor cell growth and progression. Crizotinib may stop the growth of tumor cells by ...
Known for
Tumor Growth | Adjuvant Therapy | Works Treating | Entry Phase
KOL-Index: 2 This phase II trial studies how pembrolizumab works before and after surgery in treating patients with stage III-IV high-risk melanoma. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.. Giving pembrolizumab before and after surgery may work better ...
Known for
Arms Survival | Adjuvant Mk-3475 | Confirmed Unconfirmed | Works Surgery
KOL-Index: 2 This study collects blood samples, medical information, and medical images from patients who are being treated for cancer and have a positive test for SARS CoV-2, the new coronavirus that causes the disease called COVID-19. Collecting blood samples, medical information, and medical images may help researchers determine how COVID-19 affects the outcomes of patients undergoing cancer treatment ...
KOL-Index: 2 This phase II trial studies how well OBI-3424 works in treating patients with T-cell acute lymphoblastic leukemia that has come back (relapsed) or does not response to treatment (refractory). Drugs used in chemotherapy, such as OBI-3424, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. ...
Known for
Mrd Negativity

From Mountain Rescue (England and Wales), Cumbria, England (Dr Ellerton); the Eye Clinic, University Hospital, Croatian Mountain Rescue Service, Split, Croatia (Dr Zuljan); the Italian Alpine Club Medical Commission, Colzate, Italy (Dr Agazzi); and t

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