WenHui Du: Influence Statistics

WenHui Du

WenHui Du

Anhui Medical University, 1st Affiliated Hospital, Department of Dermatology, Hefei, China, Department of Dermatology, 1st Affiliated Hospital, Anhui Medical University, ...

WenHui Du: Expert Impact

Concepts for which WenHui Du has direct influence: Acne vulgaris , Pityriasis rosea , Autoimmune diseases , Chinese patients , Missense mutation , Marie unna , Pachyonychia congenita .

WenHui Du: KOL impact

Concepts related to the work of other authors for which for which WenHui Du has influence: Psoriatic arthritis , Chinese population , Alopecia areata , Vitiligo patients , Acne vulgaris , Pediatric psoriasis , Systemic lupus erythematosus .

KOL Resume for WenHui Du


Anhui Medical University, 1st Affiliated Hospital, Department of Dermatology, Hefei, China, Department of Dermatology, 1st Affiliated Hospital, Anhui Medical University, Hefei, China.


Anhui Medical University Department of Dermatology Institute of Dermatology The First Affiliated Hospital Hefei Anhui People's Republic of China


Institute of Dermatology & Department of Dermatology, The First Hospital, Anhui Medical University, Hefei, Anhui 230032, China


The Key Laboratory of Gene Resource Utilization for Severe Genetic Diseases, Ministry of Education and Anhui Province, Hefei, China


Institute of Dermatology & Department of Dermatology at No.1 Hospital, Anhui Medical University, Hefei, China


Institute of Dermatology and Department of Dermatology, No: 1 Hospital, Anhui Medical University, 69 Meishan Road, 230032, Hefei, Anhui, China


Institute of Dermatology and Department of Dermatology, No. 1 Hospital, Anhui Medical University, and Key Laboratory of Genome Research at Anhui (Drs Gao, Wang, Yang, Hu, Zhu, Ren, Du, G.-L. Zhang, Cui, Chen, Yan, Xiao, and X.-J. Zhang), Hefei, China


Institute of Dermatology, Anhui Medical University, Department of Dermatology, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui

Prominent publications by WenHui Du

KOL-Index: 11809 . Systemic lupus erythematosus (SLE) is a complex systemic disease influenced by genetic and environmental factors. The exact pathogenesis of SLE is still unknown. Recently, several genome-wide association studies (GWA) in European population have found many novel susceptibility genes for SLE including TNFAIP3. In order to examine whether TNFAIP3 is associated with SLE in Chinese Han ...
Known for Tnfaip3 Gene | Systemic Lupus Erythematosus | Sle Chinese Population | Nucleotide Polymorphism
KOL-Index: 10954 . PSORS1 (psoriasis susceptibility gene 1) is a major susceptibility locus for psoriasis. Several fine-mapping studies have highlighted a 300-kb candidate region of PSORS1 where multiple biologically plausible candidate genes were suggested. The most recent study has indicated HLA-Cw6 as the primary PSORS1 risk allele within the candidate region in a Caucasian population. In this study, a ...
Known for Chinese Population | Psoriasis Susceptibility | Fine Mapping | Risk Haplotypes
KOL-Index: 9226 . An oligonucleotide biochip that specifically detects point mutations in the gyrA and parC genes of Neisseria gonorrhoeae was designed and subsequently evaluated with 87 untreated clinical specimens. The susceptibilities of the N. gonorrhoeae strains were tested to determine the prevalence of ciprofloxacin-resistant strains in Anhui Province, People's Republic of China. Conventional DNA ...
Known for Ciprofloxacin Resistance | Neisseria Gonorrhoeae | Oligonucleotide Biochip | Parc Mutations
KOL-Index: 7082 . OBJECTIVE: To report and analyze the mutations of the double-stranded RNA-specific adenosine deaminase (DSRAD) gene in 2 Chinese pedigrees with dyschromatosis symmetrica hereditaria (DSH). DESIGN: Pedigree study. SETTING: Anhui province of China. PATIENTS: Two Chinese families, consisting of 19 individuals (family 1) and 5 individuals (family 2). INTERVENTIONS: We directly performed ...
Known for Frameshift Mutations | Adenosine Deaminase | Dsrad Gene | Dyschromatosis Symmetrica
KOL-Index: 6467 . Brooke-Spiegler syndrome (BSS) is an autosomal dominant disease characterized by cylindromas, trichoepitheliomas and occasionally spiradenomas. The disease gene was mapped to 16q12-13, and mutations in the CYLD gene were identified in families with BSS. In the present report, we describe a large consanguineous Chinese family with BSS showing an intra-family phenotypic variability. ...
Known for Tumor Suppressor | Cyld Gene | Spiegler Syndrome | Cylindromas Trichoepitheliomas
KOL-Index: 6356 . Xuejun Zhang and colleagues report a genome-wide association and replication studies for psoriasis, conducted in Chinese populations. They confirm previous associations in MHC and IL12B to psoriasis susceptibility, and report a new association within the LCE gene cluster at 1q21.
Known for Lce Gene Cluster | Psoriasis Genome | Susceptibility Variants | Xuejun Zhang
KOL-Index: 6314 . Very few articles have aimed to illuminate the clinical profiles of vitiligo in China. We conducted this retrospective survey involving 4118 outpatients with vitiligo in order to identify the differences among various clinical types of vitiligo and their associated disorders. Completed questionnaires (3742) were validated and analysed. Of this large cohort, 1565 (41.8%) individuals ...
Known for Clinical Profiles | Patients Vitiligo | Alopecia Areata Arthritis | Age Onset
KOL-Index: 6262 . OBJECTIVES: Psoriasis is common in childhood. The aim of this study was to present the clinical and epidemiological profile of childhood psoriasis in China. METHODS: A total of 277 childhood psoriasis patients younger than 16 years old were enrolled. Statistical analysis and heritability were performed using EPI INFO 6.0, spss 10.0 and Falconer's method. RESULTS: The median age was 11 ...
Known for Childhood Psoriasis | Median Age Onset | 10 Years | Female Ratio
KOL-Index: 6222 . Darier’s disease (DD) is an autosomal dominantly inherited skin disorder characterized by loss of adhesion between epidermal cells (acantholysis) and abnormal keratinization. To date, at least 140 mutations in the ATP2A2 gene have been identified as the genetic basis of DD. Here we reported three familial and two sporadic Chinese DD patients totally with four missense mutations (N767D, ...
Known for Atp2a2 Gene | Chinese Patients | Darier Disease | Missense Mutations
KOL-Index: 6087 . Vitiligo is a common skin and hair depigmentary disorder that results from selective destruction of melanocytes. It occurs in a typical multifactorial, polygenic inheritance. Several studies have indicated that vitiligo is associated with some autoimmune diseases. In this paper we examined 6,516 vitiligo patients including clinical characteristics, familial involvement, and their ...
Known for Autoimmune Diseases | Vitiligo Patients | Rheumatoid Arthritis | Alopecia Areata
KOL-Index: 5830 . BACKGROUND: Acne is a chronic inflammatory disease of the pilosebaceous follicles. Recent studies bring us increasing evidences that hereditary factors play an important but indirect role in acne. OBJECTIVE: To investigate the possible role of genetic factors in the pathogenesis of acne vulgaris in Chinese Han ethnic group. PATIENTS AND METHODS: Volunteers of 975 acne cases and 580 ...
Known for Acne Vulgaris | Genetic Factors | Chinese Ethnic | Case Control
KOL-Index: 5072 . BACKGROUND: Marie Unna hereditary hypotrichosis (MUHH) is a rare autosomal congenital alopecia with progressive hair loss starting in early childhood and accelerating at puberty. A locus for MUHH has been mapped on chromosome 8p21 but no genes for MUHH have been identified to date. OBJECTIVES: To refine the MUHH locus to a narrow chromosome region to facilitate cloning of the ...
Known for Marie Unna | Hereditary Hypotrichosis | Locus Muhh | Chromosome 8p21
KOL-Index: 4783 . BACKGROUND: Psoriasis is a common inflammatory and hyperproliferative skin disease. The pathogenesis of psoriasis remains obscure. Family and twin studies have suggested a strong genetic susceptibility to psoriasis. Eight linkage loci (PSORS1-7, PSORS9) were identified and accepted by the OMIM and an additional 16 susceptibility loci have been suggested so far. OBJECTIVES: To investigate ...
Known for Susceptibility Loci | Psoriasis Vulgaris | Age Onset | Chromosomes Human
KOL-Index: 4505 . Melanoma, the most aggressive form of skin cancer, causes more than 40,000 deaths each year worldwide. And epidermoid carcinoma is another major form of skin cancer, which could be studied together with melanoma in several aspects. Asparagine synthetase (ASNS) gene encodes an enzyme that catalyzes the glutamine- and ATP-dependent conversion of aspartic acid to asparagine, and its ...
Known for Asparagine Synthetase | Cell Growth | Knockdown Asns | Human Cancers
KOL-Index: 4371 . BACKGROUND: Some studies suggested that human HLA status may potentiate development of the AA phenotype and exists ethic differences. No report has been published about HLA class I alleles associated with AA in Chinese Hans. OBJECTIVE: To study the distribution of HLA class I alleles and haplotypes in Chinese Hans AA patients and the relation of HLA class I profile with age of onset, ...
Known for Age Onset | Aa Chinese | Antigen Hla | Alleles Alopecia

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Anhui Medical University, 1st Affiliated Hospital, Department of Dermatology, Hefei, China, Department of Dermatology, 1st Affiliated Hospital, Anhui Medical University, Hefei, China. | Anhui Medical University Department of Dermatology Institute of