Elizabeth A Holly†

Elizabeth A Holly†


Prominent publications by Elizabeth A Holly†

KOL Index score: 18269

OBJECTIVES: To study anal intraepithelial neoplasia and its associations with anal and cervical human papillomavirus (HPV), cervical neoplasia, host immune status, and demographic and behavioral risk factors in women with and at risk for HIV infection.

DESIGN: Point-prevalence analysis nested within a prospective study of women seen at three clinical centers of the Women's Interagency HIV Study.

METHODS: In 2001-2003 participants were interviewed, received a gynecological examination, ...

Known for Anal Intraepithelial |  Infected Women |  Risk Hiv |  Cervical Neoplasia |  Multisite Study
KOL Index score: 17871

Cutaneous malignant melanoma occurs less frequently among non-Whitepopulations than among Whites. As a result, little is known about theincidence and epidemiology of melanoma among other race/ethnicity groups.Data from the California Cancer Registry (United States) among 879 Hispanic,126 Asian, and 85 Black men and women diagnosed with melanoma in 1988-93 wereanalyzed and compared with data for 17,765 non-Hispanic White cases. Average,annual, age-adjusted incidence rates per 100,000 ...

Known for Hispanic Whites |  Cutaneous Melanoma |  Asians Blacks |  California Cancer Registry |  Continental Ancestry
KOL Index score: 14902

BACKGROUND: Anal cancers are thought to arise from squamous intraepithelial lesions in the anal canal, and women infected with human immunodeficiency virus-1 (HIV) may be at higher risk of anal cancer. Our aim was to determine the prevalence of human papillomavirus (HPV)-related abnormalities of the anal canal in women and to characterize risk factors for these lesions.

METHODS: We evaluated HPV-related abnormalities in 251 HIV-positive and in 68 HIV-negative women. We completed physical ...

Known for Anal Squamous |  Intraepithelial Lesions |  Women Hiv |  Risk Abnormal |  Human Immunodeficiency
KOL Index score: 14367

In an International Lymphoma Epidemiology Consortium pooled analysis, polymorphisms in 2 immune-system-related genes, tumor necrosis factor (TNF) and interleukin-10 (IL10), were associated with non-Hodgkin lymphoma (NHL) risk. Here, 8,847 participants were added to previous data (patients diagnosed from 1989 to 2005 in 14 case-control studies; 7,999 cases, 8,452 controls) for testing of polymorphisms in the TNF -308G>A (rs1800629), lymphotoxin-alpha (LTA) 252A>G (rs909253), IL10 -3575T>A ...

Known for Tumor Necrosis Factor |  Interlymph Consortium |  Hodgkin Lymphoma |  Odds Ratios |  Polymorphisms Tnf
KOL Index score: 13888

BACKGROUND: Common genetic variants in immune and inflammatory response genes can affect the risk of developing non-Hodgkin lymphoma. We aimed to test this hypothesis using previously unpublished data from eight European, Canadian, and US case-control studies of the International Lymphoma Epidemiology Consortium (InterLymph).

METHODS: We selected 12 single-nucleotide polymorphisms for analysis, on the basis of previous functional or association data, in nine genes that have important ...

Known for Interlymph Consortium |  Hodgkin Lymphoma |  Tnf Il10 |  Genetic Variation |  Genotype Data
KOL Index score: 13755

Anal squamous intraepithelial lesions (ASIL) are common in homosexual and bisexual men, and high-grade ASIL (HSIL) in particular may represent an anal cancer precursor. Cervical cytology is a useful screening tool for detection of cervical HSIL to prevent cervical cancer. To assess anal cytology as a screening tool for anal disease, we compared anal cytology with anoscopy and histopathology of anal biopsies. A total of 2958 anal examinations were performed on 407 HIV-positive and 251 ...

Known for Anal Cytology |  Screening Tool |  Sensitivity Specificity |  Squamous Intraepithelial |  Situ Carcinoma
KOL Index score: 13547

OBJECTIVE: The incidence of anal cancer among homosexual men exceeds that of cervical cancer in women, and HIV-positive homosexual men may be at even higher risk than HIV-negative men. Cervical cancer is preceded by high-grade squamous intra-epithelial lesions (HSIL) and anal HSIL may similarly be the precursor to anal cancer. In this study, we describe the incidence of and risk factors for HSIL in HIV-positive and HIV-negative homosexual and bisexual men.

DESIGN: Prospective cohort ...

Known for Negative Homosexual |  San Francisco |  Hiv Positive |  Incidence Anal Cancer |  Grade Squamous
KOL Index score: 13308

BACKGROUND & AIMS: Pancreatic cancer usually does not cause definitive symptoms until survival is severely compromised. Prevention and early detection are urgently needed. Our aim was to collect and analyze data in a population-based study on signs and symptoms of disease reported by patients with pancreatic cancer and control participants to contribute to earlier detection and better prognosis.

METHODS: A supplemental symptoms questionnaire was administered to 120 consecutive patients ...

Known for Pancreatic Cancer |  Signs Symptoms |  San Francisco |  Based Case |  Bay Area
KOL Index score: 13081

BACKGROUND: Diabetes has been postulated to be both a risk factor and a consequence of pancreatic cancer, but the degree of risk and associated clinical factors remain unclear.

METHODS: We conducted a population-based case-control study of pancreatic cancer in the San Francisco Bay Area between 1995 and 1999. Rapid case ascertainment through the Surveillance, Epidemiology and End Results registry for cases and random selection from the general population for controls were employed to ...

Known for Pancreatic Cancer |  San Francisco |  Diabetes Mellitus |  Bay Area |  Based Case
KOL Index score: 13068

Anal cancer may be preceded by anal squamous intraepithelial lesions (ASIL), but the natural history of ASIL is poorly understood. In this report, we characterize the 2-year incidence and progression of low-grade SIL (LSIL) and high-grade SIL (HSIL) in a cohort study in 346 HIV-positive and 262 HIV-negative homosexual or bisexual men. Subjects were studied at defined intervals using anal cytology, anoscopy with biopsy of visible lesions, human papillomavirus (HPV) testing, HIV ...

Known for Negative Homosexual |  Anal Squamous |  Lsil Hsil |  Intraepithelial Lesions |  Situ Carcinoma
KOL Index score: 12969

A role for genetic susceptibility in non-Hodgkin lymphoma (NHL) is supported by the accumulating evidence of common genetic variations altering NHL risk. However, the pattern of NHL heritability remains poorly understood. We conducted a pooled analysis of 10 211 NHL cases and 11 905 controls from the International Lymphoma Epidemiology Consortium (InterLymph) to evaluate NHL risk among those with hematopoietic malignancies in first-degree relatives. Odds ratios (ORs) and 95% confidence ...

Known for Pooled Analysis |  Hodgkin Lymphoma |  Nhl Risk |  Hematopoietic Malignancies |  Epidemiology Consortium
KOL Index score: 12409

The incidence of anal cancer is elevated in human immunodeficiency virus (HIV)-infected men-who-have-sex-with-men (MSM) compared to the general population. Anal high-grade squamous intraepithelial lesions (HSIL) are common in HIV-infected MSM and the presumed precursors to anal squamous cell cancer; however, direct progression of HSIL to anal cancer has not been previously demonstrated. The medical records were reviewed of 138 HIV-infected MSM followed up at the University of California, ...

Known for Anal Cancer |  Squamous Intraepithelial |  Male Humans |  Situ Carcinoma |  Treatment Hsil


Elizabeth A Holly†: Influence Statistics

Sample of concepts for which Elizabeth A Holly† is among the top experts in the world.
Concept World rank
diagnostic san #1
hpv16 e6 sequence #1
western controls #1
melanoma patients 17 #1
msm sensitivity #1
cbts children #1
70 cliniciancollected samples #1
hpvassociated anogenital cancers #1
npy snps 1258ga #1
pancreatic cancer signs #1
15 mother #1
factors topic lymphoma #1
hsil tests #1
hpv homosexual bisexual #1
1 9 vaccination #1
hsil hivinfected msm #1
pancreatic cancer duration #1
horses child #1
angeles county cbt #1
mothers beauty products #1
lymphoma patients real #1
incidence negative homosexual #1
bisexual incidence #1
reliability mothers #1
risk factor pca #1
metformin nondiabetics #1
early pregnancy melanoma #1
haircoloring agents #1
“other” thyroid conditions #1
ppv ahsil #1
complete followup authors #1
semipermanent dye month #1
cbt increased ors #1
2515 control subjects #1
animal oncogenic viruses #1
tnfrsf5 polymorphism #1
hiv cnas #1
controls study participants #1
reliability jobs #1
hsil homosexual #1
af1a variant #1
household rooms nhl #1
nonrecent occupational agents #1
nhl cigarette smoking #1
ahsil lesions #1
asians hispanic whites #1
56 case #1
cbt farm #1
r01 ca63933 #1
farm animals cbt #1

Key People For Pancreatic Cancer

Top KOLs in the world
Ralpha H Hruban†
pancreatic cancer gene expression tumor carcinoma
Ahmedin M Jemal
united states breast cancer addis ababa
Rebecca L Siegel
united states colorectal cancer incidence rates
Anirban Maitra
pancreatic cancer precursor lesions early detection
Markus Wolfgang Büchler†
pancreatic cancer chronic pancreatitis liver transplantation
Helmut M Friess†
pancreatic cancer chronic pancreatitis growth factor

Elizabeth A Holly†:Expert Impact

Concepts for whichElizabeth A Holly†has direct influence:Pancreatic cancer,  San francisco,  Pooled analysis,  Hodgkin lymphoma,  Cutaneous melanoma,  Brain tumors,  Interlymph consortium,  Anal cancer.

Elizabeth A Holly†:KOL impact

Concepts related to the work of other authors for whichfor which Elizabeth A Holly† has influence:Pancreatic cancer,  Human papillomavirus,  Hodgkin lymphoma,  United states,  Cutaneous melanoma,  Sun exposure,  Anal cytology.



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Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA | Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. | Dept of Epidemiology a

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