Prominent publications by Fay Bahling Horak

KOL Index score: 18680

OBJECTIVE: To quantify postural sway in subjects with Parkinson's disease and elderly controls, and determine the effects of Parkinson's disease, deep brain stimulation, levodopa, and their interactions on postural control during quiet stance.

METHODS: Centre of foot pressure (CoP) displacement under each foot was measured during three 60 s trials of quiet stance with eyes open in 11 controls and six patients with Parkinson's disease. Subjects with Parkinson's disease were tested in four ...

Also Ranks for: Deep Brain Stimulation |  postural sway |  parkinsons disease |  quiet stance |  subjects parkinson
KOL Index score: 15362

OBJECT: Difficulty with step initiation, called "start hesitation," is related to gait bradykinesia and is an early hallmark of gait freezing in Parkinson disease (PD). Authors of this study investigated the effects of deep brain stimulation (DBS) and levodopa on step initiation before and 6 months after DBS surgery in 29 patients with PD who were randomized to either the bilateral subthalamic nucleus (STN) or globus pallidus internus (GPi) as the DBS site.

METHODS: The authors measured ...

Also Ranks for: Parkinson Disease |  subthalamic nucleus |  deep brain stimulation |  dbs stn |  step initiation
KOL Index score: 13973

Freezing of gait is one of the most debilitating symptoms in Parkinson's disease as it causes falls and reduces mobility and quality of life. The pedunculopontine nucleus is one of the major nuclei of the mesencephalic locomotor region and has neurons related to anticipatory postural adjustments preceding step initiation as well as to the step itself, thus it may be critical for coupling posture and gait to avoid freezing. Because freezing of gait and postural impairments have been ...

Also Ranks for: Gait Freezing |  pedunculopontine nucleus |  parkinsonian patients |  structural connectivity |  executive function
KOL Index score: 13760

BACKGROUND: The Balance Evaluation Systems Test (BESTest) is a new clinical balance assessment tool, but it has never been validated in patients with subacute stroke.

OBJECTIVE: The purpose of this study was to examine the reliability and validity of the BESTest in patients with subacute stroke.

DESIGN: This was an observational reliability and validity study.

METHODS: Twelve patients participated in the interrater and intrarater reliability study. Convergent validity was investigated in ...

Also Ranks for: Subacute Stroke |  balance evaluation |  bbs mini |  reliability validity |  sensitivity specificity
KOL Index score: 13720

1. This study investigates the effects of parkinsonism and of dopamine replacement therapy (levodopa) on scaling the magnitude of automatic postural responses based on sensory feedback and on predictive central set. Surface reactive torques and electromyographic (EMG) activity in response to backward surface translations were compared in patients with parkinsonism ON and OFF levodopa and in elderly control subjects. Correlations between the earliest postural responses [initial rate of ...

Also Ranks for: Parkinsonian Subjects |  postural control |  muscle tone |  emg activity |  displacement velocity
KOL Index score: 13289

The relative contribution of vestibular and somatosensory information to triggering postural responses to external body displacements may depend on the task and on the availability of sensory information in each system. To separate the contribution of vestibular and neck mechanisms to the stabilization of upright stance from that of lower body somatosensory mechanisms, responses to displacements of the head alone were compared with responses to displacements of the head and body, in both ...

Also Ranks for: Responses Head |  support surface |  vestibular function |  leg muscle |  subjects patients
KOL Index score: 13035

BACKGROUND: The voluntary, maximum inclined posture reflects the self-perceived limits of stability. Parkinson's disease is associated with small, bradykinetic postural weight shifts while standing but it is unclear whether this is due to reduced limits of stability and/or to the selection of abnormal strategies for leaning. The aim of this study was to investigate the effects of Parkinson's disease and levodopa medication on voluntary limits of stability and strategies used to reach ...

Also Ranks for: Functional Limits |  parkinsons disease |  center pressure |  postural strategies |  stability parkinson
KOL Index score: 12722

Freezing of gait (FoG) is associated with less automatic gait and more impaired cognition, balance and postural transitions compared to people with PD who do not have FoG. However, it is unknown whether dual-task cost during postural sway, postural transitions (such as gait initiation and turning), and gait are more in subjects with Parkinson's disease (PD) who have freezing of gait (FoG+) compared to those who do not have FoG (FoG-). Here, we hypothesized that the effects of a cognitive ...

Also Ranks for: Postural Sway |  dual task |  gait fog |  parkinson disease |  turning walking
KOL Index score: 12665

KEY POINTS: Individuals with freezing of gait (FoG) due to Parkinson's disease (PD) have small and long anticipatory postural adjustments (APAs) associated with delayed step initiation. Individuals with FoG ('freezers') may require functional reorganization of spinal mechanisms to perform APAs due to supraspinal dysfunction. As presynaptic inhibition (PSI) is centrally modulated to allow execution of supraspinal motor commands, it may be deficient in freezers during APAs. We show that ...

Also Ranks for: Presynaptic Inhibition |  step initiation |  parkinsonian individuals |  gait fog |  quiet stance
KOL Index score: 12248

BACKGROUND: The reliability and convergent validity of the Balance Evaluation Systems Test (BESTest) in people with subacute stroke have been established, but its responsiveness to rehabilitation has not been examined.

OBJECTIVE: The study objective was to compare the responsiveness of the BESTest with those of other clinical balance tools in people with subacute stroke.

DESIGN: This was a prospective cohort study.

METHODS: Forty-nine people with subacute stroke (mean age=57.8 years, ...

Also Ranks for: Subacute Stroke |  balance evaluation |  mini bestest |  systems test |  internal responsiveness
KOL Index score: 12168

1. In this study, the interaction between anticipatory postural adjustments for step initiation and automatic postural responses to an external perturbation were investigated by having subjects initiate a voluntary forward step while perturbed by a backward surface translation, which caused forward sway of the body. The postural adjustments for step initiation act to move the body center of mass (COM) forward, whereas the automatic postural responses act to move the COM backward to ...

Also Ranks for: Step Initiation |  postural responses |  swing limb |  surface translation |  foot pressure
KOL Index score: 12022

BACKGROUND: Current clinical balance assessment tools do not aim to help therapists identify the underlying postural control systems responsible for poor functional balance. By identifying the disordered systems underlying balance control, therapists can direct specific types of intervention for different types of balance problems.

OBJECTIVE: The goal of this study was to develop a clinical balance assessment tool that aims to target 6 different balance control systems so that specific ...

Also Ranks for: Systems Test |  balance evaluation |  concurrent validity |  interrater reliability |  abc scale
KOL Index score: 11948

OBJECT: While deep brain stimulation (DBS) has proven to be an effective treatment for many symptoms of Parkinson disease (PD), a deterioration of axial symptoms frequently occurs, particularly for speech and swallowing. These unfavorable effects of DBS may depend on the site of stimulation. The authors made quantitative measures of jaw velocity to compare the relative effectiveness of DBS in the globus pallidus internus (GPi) or the subthalamic nucleus (STN). This was a randomized, ...

Also Ranks for: Parkinson Disease |  deep brain stimulation |  dbs gpi |  subthalamic nucleus stn |  6 months
KOL Index score: 11928

The purpose of this work was to determine whether fingertip touch on a stable surface could improve postural stability during stance in subjects with somatosensory loss in the feet from diabetic peripheral neuropathy. The contribution of fingertip touch to postural stability was determined by comparing postural sway in three touch conditions (light, heavy and none) in eight patients and eight healthy control subjects who stood on two surfaces (firm or foam) with eyes open or closed. In ...

Also Ranks for: Postural Stability |  fingertip touch |  force plate |  patients peripheral neuropathy |  somatosensory loss
KOL Index score: 11881

1. The effect of central set on automatic postural responses was studied in humans exposed to horizontal support-surface perturbations causing forward sway. Central set was varied by providing subjects with prior experience of postural stimulus velocities or amplitudes under 1) serial and random conditions, 2) expected and unexpected conditions, and 3) practiced and unpracticed conditions. In particular, the influence of central-set conditions was examined on the pattern and magnitude of ...

Also Ranks for: Postural Responses |  prior experience |  perturbation amplitude |  unexpected conditions |  ankle torque

Key People For Parkinson Disease

Top KOLs in the world
Andrew **** ******
parkinsons disease progressive supranuclear motor fluctuations
Anthony ****** ****
parkinson disease movement disorders subthalamic nucleus
Werner * *****
parkinson disease multiple atrophy restless legs syndrome
Christopher * *****
parkinson disease movement disorders rating scales
Charles * ******
parkinson disease oxidative stress motor complications
Joseph * ********
movement disorders parkinson disease essential tremor

Fay Bahling Horak:Expert Impact

Concepts for whichFay Bahling Horakhas direct influence:Parkinson disease,  Postural responses,  Postural sway,  Postural control,  Parkinsons disease,  Step initiation,  Multiple sclerosis,  Deep brain stimulation.

Fay Bahling Horak:KOL impact

Concepts related to the work of other authors for whichfor which Fay Bahling Horak has influence:Postural control,  Parkinson disease,  Multiple sclerosis,  Deep brain stimulation,  Balance training,  Basal ganglia,  Gait initiation.



Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

APDM Wearable Technologie—A Clario Company, 2828 S Corbett Ave, Ste 135, Portland, OR 97201, USA; (K.S.); (M.E.-G.); (J.M.) | Department of Neurology, Oregon Health and Science University, Portland, OR, USA. | Department of Neurology, Oregon Health &