• Prenatal Diagnosis
    • Huge Fetal Hepatic...
    • Huge fetal hepatic Hemangioma: prenatal diagnosis on ultrasound and prognosis: Influence Statistics

      Expert Impact

      Concepts for whichthey havehas direct influence:Prenatal diagnosis,Hepatic hemangioma,Hepatic hemangiomas,Fetuses lesions,Imaging features,Imaging pregnancy,Pregnancy prenatal,Liver neoplasms.

      Key People For Prenatal Diagnosis

      Top KOLs in the world
      Kypros Nicolaides Nicolaides†
      cervical length gestational age maternal factors
      John M Opitz
      publication abnormalities rett syndrome prenatal diagnosis
      Mitchell S Golbus
      prenatal diagnosis chorionic villus sampling amniotic fluid
      John C Hobbins
      amniotic fluid prenatal diagnosis preterm labor
      Charles H Rodeck
      prenatal diagnosis fetal blood amniotic fluid
      Joe Leigh Leigh Simpson
      maternal blood prenatal diagnosis fetal cells

      Huge fetal hepatic Hemangioma: prenatal diagnosis on ultrasound and prognosis


      BACKGROUND: Although huge fetal hepatic hemangiomas are rare, they can cause fatal complications. The purpose of this study is to describe the imaging features and prognosis of these tumors.

      METHODS: Imaging data were collected for 6 patients with huge fetal hepatic hemangiomas treated at our hospital. Imaging modalities included prenatal magnetic resonance imaging and ultrasound and postnatal color Doppler ultrasound and contrast-enhanced computed tomography (CT).

      RESULTS: Among the 93,562 fetuses of 92,126 pregnant women examined at our hospital, 6 had huge hepatic hemangiomas (incidence rate, 0.64/10,000), as confirmed via postnatal color Doppler imaging and contrast-enhanced CT. Five fetuses had solitary lesions, whereas 1 (fetus 2) had multiple lesions. Four fetuses had lesions in the right liver lobe and 1 had a lesion in the left liver lobe, and 1 (fetus 2) had lesions in both lobes. All lesions showed centripetal enhancement on postnatal contrast-enhanced CT, which was more intense peripherally. Following postnatal treatment with oral propranolol, with or without dexamethasone or interventional therapy with the medical sclerosant pingyangmycin, all lesions decreased in size, with calcification plaques appearing 6 months after treatment.

      CONCLUSIONS: Huge hepatic hemangiomas have typical ultrasonographic features and can be diagnosed prenatally. Treatment with propranolol, with or without dexamethasone, may result in a favorable prognosis.

      Sign-in to see all concepts, it's free!


    Download on the App StoreGet it on Google Play

    Copyright © 2023 Key Opinion Leaders, LLC.