• KOL
    • Oral Lichen Planus
    • Hao Xu
    • Hao Xu: Influence Statistics

      Hao Xu

      Hao Xu

      Show email address

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical ...

      Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

      Hao Xu:Expert Impact

      Concepts for whichHao Xuhas direct influence:Oral lichen planus,Lichen planus,Squamous cell,Cell carcinoma,Oral squamous,Photodynamic therapy,Oral lichen,Topical administration.

      Hao Xu:KOL impact

      Concepts related to the work of other authors for whichfor which Hao Xu has influence:Sarscov2 infection,Oral cancer,Coronavirus disease covid19,Ace2 expression,Converting enzyme,Spike protein,Viral load.

      KOL Resume for Hao Xu

      Year
      2022

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China

      2021

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, China

      2020

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan China

      2019

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China

      2017

      Department of Oral Biology and Medicine, State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, 610041, Chengdu, China

      2016

      State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China

      2015

      State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China

      2014

      State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University

      Sign-in to see all concepts, it's free!
      Sample of concepts for which Hao Xu is among the top experts in the world.
      Concept World rank
      fluocinolone worst smd #2
      tacrolimus symptomreducing #2
      fluocinolone worst #2
      ulceration rhu #2
      worst smd dexamethasone #2
      fluocinolone tacrolimus #2
      pga reu score #2
      betamethasone efficacy #2
      clobetasol pscore #2
      planus network #2
      symptomreducing #2
      pscore clobetasol #2
      scoring reticulation #2
      reticulation hyperemia #2
      pimecrolimus cyclosporine #2
      rhu score #2
      rhu score pga #2
      clobetasol betamethasone #2
      tacrolimus symptom #2
      rhu nrs #2
      pscore fluocinolone #2
      score rhu #2
      clobetasol performed #2
      clobetasol worst smd #2
      pga reu #2
      rhu scoring #2
      satisfactory standard validity #2
      nrs rhu #2
      olp scoring #2
      pimecrolimus performed #2
      fortyeight olp patients #2
      pimecrolimus pscore #2
      hyperemia ulceration #2
      cyclosporine worst #2
      olp patients management #2
      applied rhu #2
      pscore cyclosporine #2
      hyperemia ulceration lesions #2
      visit ohip14 #2
      pscore tacrolimus #2
      dexamethasone sign #2
      fluocinolone safety #2
      new scoring reliability #2
      rhu rhu scoring #2
      clobetasol worst #2
      worst smd #2
      reflecting satisfactory #3
      standard reflecting #3
      sign reducing #3
      olp terms #4
      Sign-in to see all concepts, it's free!

      Prominent publications by Hao Xu

      KOL-Index: 9735

      It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell to cause the final infection. To investigate the potential route of 2019-nCov infection on the mucosa of oral cavity, bulk RNA-seq profiles from two public databases including The Cancer Genome Atlas (TCGA) and Functional Annotation of The Mammalian Genome Cap Analysis of Gene Expression (FANTOM5 CAGE) dataset were collected. RNA-seq profiling data of 13 ...

      Known for Epithelial Cells | Ace2 Receptor | Oral Cavity | Normal Tissues | 2019 Ncov
      KOL-Index: 9578

      BACKGROUND: PA28γ was suggested to play a role in malignant progression. This paper aimed to investigate the association between PA28γ and the prognosis of oral squamous cell carcinoma (OSCC) in cohort studies.

      METHODS: The PA28γ expression level was assessed by immunohistochemistry in a total of 368 OSCC patients from three independent cohorts. The Cox proportional hazards regression model was used to determine multivariate hazard ratios for Overall Survival (OS). Model discrimination ...

      Known for Cell Carcinoma | Pa28γ Expression | Oral Squamous | Oscc Cohort Studies | Malignant Progression
      KOL-Index: 9434

      BACKGROUND: TCS (topical corticosteroids) are the first-line drug in the treatment of oral lichen planus (OLP). However, the value of topical calcineurin inhibitors (TCI) including tacrolimus, pimecrolimus and ciclosporin for OLP is still controversial.

      OBJECTIVES: To compare the efficacy and safety of TCI vs. TCS for OLP.

      METHODS: The authors searched PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science and four Chinese databases from 1950 to May 2018. The ...

      Known for Lichen Planus | Topical Calcineurin Inhibitors | Tacrolimus Pimecrolimus | Efficacy Safety | Treatment Olp
      KOL-Index: 7907

      OBJECTIVES: To investigate the expression and prognostic value of B7-H6 protein in oral squamous cell carcinoma tissues.

      MATERIALS AND METHODS: A total of 50 oral squamous cell carcinoma samples, 10 oral leukoplakia (OLK) samples, and 17 normal controls were included in the analysis. The expression of B7-H6 in oral squamous cell carcinoma, OLK, and normal controls was evaluated by immunohistochemical assay.

      RESULTS: The B7-H6 protein expression was significantly higher in oral squamous ...

      Known for Squamous Cell | B7 H6 | Mouth Neoplasms
      KOL-Index: 6878

      BACKGROUND: AKT1 is an important downstream effector of PTEN/PI3K/AKT signal transduction pathway. Aberrant expression and genetic variant of AKT1 gene are suggested to be involved in several types of human cancers, including OSCC. The aim of this study was to investigate the possible association between AKT1 gene polymorphisms and OSCC in Chinese Han Population.

      METHODS: A total of 182 OSCC patients and 207 cancer-free controls were enrolled for this hospital-based study. Five ...

      Known for Akt1 Gene | Chinese Population | Single Nucleotide | Rs1130214 Rs3803300 | Akt Risk
      KOL-Index: 6325

      Interleukin 37 (IL-37) has been reported to play a significant role in innate immune response and to be involved in several kinds of cancers. However, the investigation of association between IL-37 and oral mucosa carcinogenesis hasn't been clearly established. The aim of the study was to assess IL-37 expression and explore its role in oral mucosa carcinogenesis. The expression of IL-37 increased from normal control (NC) to Oral leukoplakia (OLK) and oral squamous cell carcinoma (OSCC). ...

      Known for Squamous Cell | Oral Leukoplakia | Tumor Carcinoma | Il37 Expression | Mucosa Mouth
      KOL-Index: 5979

      Presently, various studies had investigated the accuracy of autofluorescence in diagnosing oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) with diverse conclusions. This study aimed to assess its accuracy for OSCC and OPMD and to investigate its applicability in general dental practice. After a comprehensive literature search, a meta-analysis was conducted to calculate the pooled diagnostic indexes of autofluorescence for premalignant lesions (PML) and ...

      Known for Squamous Cell | Malignant Disorders | Carcinoma Oscc | Accuracy Autofluorescence | Oral Cavity
      KOL-Index: 5803

      BACKGROUND: 5-Fluorouracil (5-FU) is an essential chemotherapeutic agent for oral squamous cell carcinoma (OSCC). However, toxic side effects have limited its role in OSCC therapy. The aim of this study was to explore whether combination therapy with 5-FU and honokiol (HNK), a small natural organic molecule shown to induce apoptosis in OSCC cells, could enhance the anticancer activity of 5-FU without notably increasing its toxicity.

      METHODS: 5-FU and/or HNK were used to treat OSCC cells ...

      Known for Cell Carcinoma | Anticancer Activity | 5 Fluorouracil | Oral Squamous | Mouth Neoplasms
      KOL-Index: 5709

      The lineage specification of mesenchymal stem/stromal cells (MSCs) is tightly regulated by a wide range of factors. Recently, the versatile functions of ZBP1 (also known as DAI or DLM-1) have been reported in the blood circulation and immune systems. However, the biological function of ZBP1 during the lineage specification of MSCs is still unknown. In the present study, we found that ZBP1 was upregulated during osteogenesis but downregulated during adipogenesis in mouse bone ...

      Known for Osteogenic Differentiation | Stem Cells | Catenin Signaling | Wnt Β | Marrow Adipocytes
      KOL-Index: 5522

      OBJECTIVES: Clonazepam has been used in the treatment of burning mouth syndrome (BMS) for several decades. We conducted a meta-analysis to investigate the efficacy of clonazepam in the treatment of BMS.

      METHODS: We conducted a search of the PubMed, MEDLINE, EMBASE, Web of Science (TS), and the Cochrane Library databases for relevant studies that met our eligibility criteria (up to September 22, 2015). Statistical analyses were conducted using RevMan 5.2 and STATA 11.0 software.

      RESULTS: ...

      Known for Burning Mouth | Patients Bms | Cochrane Library | Syndrome Clonazepam | Oral Pain
      KOL-Index: 5094

      BackgroundPhotodynamic therapy (PDT) is a new option for oral lichen planus (OLP) management; however, there are different opinions on the efficacy of PDT for OLP. The aim of this study was to comprehensively assess the efficacy of PDT in the treatment of OLP and compare PDT with steroid therapy.MethodsA systematic review and meta-analysis were conducted to assess the curative effect of PDT. Five electronic databases were searched, PubMed, Web of Science, the Cochrane Library, Embase, ...

      Known for Oral Lichen Planus | Photodynamic Therapy | Pdt Treatment | Methylene Blue | Topical Corticosteroid
      KOL-Index: 5062

      OBJECTIVES: To evaluate the effectiveness and safety of nucleoside antiviral drugs for the treatment of recurrent herpes labialis.

      METHODS: Randomized controlled trials that examined the effectiveness and/or safety of nucleoside antiviral drugs for recurrent herpes labialis were identified via a literature search. The parameters used to measure efficacy were time to healing of classic and all lesions, time to resolution of pain, and percentage of aborted lesions. Safety was assessed by ...

      Known for Antiviral Drugs | Herpes Labialis | Healing Lesions | Treatment Recurrent | Topical Formulations
      KOL-Index: 5016

      Transcription factors c-Jun and Fra-1 have been reported to play a role during the initiation and progression in oral squamous cell carcinoma (OSCC). However, cohort studies are rarely reported. Here is an integrative analysis of their prognostic value in OSCC through a multicenter cohort study.313 OSCC patients were included in this study and received regular follow-up. The survival rate and hazard ratios(HR) were generated by survival analysis. The concordance probability and receiver ...

      Known for Fra1 Expression | Squamous Cell | Transcription Factors | Neoplastic Humans | Oncogene Proteins
      KOL-Index: 4628

      OBJECTIVES: To estimate the association of human papillomavirus (HPV) infection with oral lichen planus (OLP) and oral leukoplakia (OLK), and determine risk cofactors.

      STUDY DESIGN: Seven databases were searched for case-control or cross-sectional studies of OLP and OLK with healthy controls, published between 1976 and 2020. The Meta package of R software was applied to calculate the pooled odds ratios (OR) and 95% confidence interval (CI).

      RESULTS: Thirty-six articles were finally ...

      Known for Oral Lichen Planus | Human Papillomavirus | Hpv Infection | Leukoplakia Olk
      KOL-Index: 4347

      To assess the impact of photodynamic therapy (PDT) parameters in the management of oral potentially malignant disorders (OPMDs). We conducted a systematic review and meta-analysis of studies that assessed the curative effect of PDT published in PubMed and Embase until Dec 2018. Random or fixed effects models for pooled estimates calculation were used. A pooled estimate calculation revealed that lesion size decreased by 1.38 cm2 (95% CI: 0.39-2.36) after PDT, and the overall complete ...

      Known for Photodynamic Therapy | Malignant Disorders | Lesion Size | Complete Response | Oral Lichen Planus

      Key People For Oral Lichen Planus

      Top KOLs in the world
      #1
      Crispian M Scully
      oral cancer lichen planus recurrent aphthous stomatitis
      #2
      Marco Carrozzo
      lichen planus mucous membrane oral medicine
      #3
      Isaa¨c van der Waal
      oral leukoplakia squamous cell carcinoma lichen planus
      #4
      Philip B Sugerman
      lichen planus oral cancer mast cell degranulation
      #5
      Kobkan Thongprasom
      lichen planus thai patients oral medicine
      #6
      Palle Holmstrup
      lichen planus autogenous bone nude mice

      State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sic

    Download on the App StoreGet it on Google Play

    Copyright © 2023 Key Opinion Leaders, LLC.