Claire L. Hogg

Claire L. Hogg

Royal Brompton & Harefield Nhs Foundation Trust, Royal Brompton Hospital, Sydney Street, Sw3 6np, London, Uk

Direct Impact

Concepts for which Claire L Hogg has direct influence:

primary ciliary dyskinesia
electron tomography
lung function
motile cilia
azithromycin maintenance therapy
cystic fibrosis
pulmonary exacerbation

External impact

Concepts related to the work of other authors for which Claire L Hogg has influence:

primary ciliary dyskinesia
genetic conditions
motile cilia
cystic fibrosis
intensively children
lung function
azithromycin maintenance therapy

Prominent publications by Claire L. Hogg

KOL-Index: 154 Primary ciliary dyskinesia (PCD) is an inherited ciliopathy leading to chronic suppurative lung disease, chronic rhinosinusitis, middle ear disease, sub-fertility and situs abnormalities. As PCD is rare, it is important that scientists and clinicians foster international collaborations to share expertise in order to provide the best possible diagnostic and management strategies. 'Better ...
Known for
Middle Ear | Ideas | Expertise | Scientists
KOL-Index: 64 Primary ciliary dyskinesia (PCD) is an inherited disorder of clinical and genetic heterogeneity resulting from mutations in genes involved in the transport, assembly and function of motile cilia. The resulting impairment in mucociliary clearance means patients suffer from chronic progressive lung disease, bronchiectasis, rhinosinusitis and middle ear disease. Subfertility is common to both ...
Known for
Complex Conditions | Situs Abnormalities | Ciliopathies Primary | Dyskinesia Pcd
KOL-Index: 64 INTRODUCTION: Primary ciliary dyskinesia (PCD) is a rare, mostly autosomal-recessive disorder of motile cilia, characterized by chronic lung disease, rhinosinusitis, hearing impairment, and subfertility. PCD is still often missed or diagnosed late since symptoms overlap with common respiratory complaints, but should be considered if one or more of the cardinal clues are present. Areas ...
Known for
Subfertility | Ciliary Beat Pattern | Tympanostomy Tube Insertion | Nasal Nitric Oxide
KOL-Index: 61 Human cilia were once thought merely to be important in respiratory mucociliary clearance, with primary ciliary dyskinesia (PCD) the sole manifestation of ciliary dysfunction. There are now known to be three types of cilia: primary, nodal and motile. Cilia are complex, likely involving more than 1000 gene products; in this review, recent advances in PCD genetics, and the potential ...
Known for
Upper Lower Airway Infection | 1000 Gene Products | Cilia Primary | Pcd Respiratory
KOL-Index: 39 Symptoms of primary ciliary dyskinesia (PCD) are nonspecific and guidance on whom to refer for testing is limited. Diagnostic tests for PCD are highly specialised, requiring expensive equipment and experienced PCD scientists. This study aims to develop a practical clinical diagnostic tool to identify patients requiring testing.Patients consecutively referred for testing were studied. ...
Known for
75 12 | Full-Term Gestation | Persistent Wet Cough | Diagnostic Prediction Rule
KOL-Index: 36 Introduction: In primary ciliary dyskinesia (PCD) impaired mucociliary clearance leads to recurrent airway infections and progressive lung destruction, and concern over chronic airway infection and patient-to-patient transmission is considerable. So far, there has been no defined consensus on how to control infection across centres caring for patients with PCD. Within the BEAT-PCD network, ...
KOL-Index: 31 Clinical data on primary ciliary dyskinesia (PCD) are limited, heterogeneous and mostly derived from retrospective chart reviews, leading to missing data and unreliable symptoms and results of physical examinations. We need standardised prospective data collection to study phenotypes, severity and prognosis and improve standards of care. A large, international and multidisciplinary group of ...
Known for
Standardised Prospective | Pcd Primary | Routine Completed | Content Structure
KOL-Index: 29 Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity. Classic symptoms include neonatal respiratory distress, chronic rhinitis since early childhood, chronic otitis media, recurrent airway infections leading to bronchiectasis, chronic sinusitis, laterality defects with and without ...
Known for
Pcd Training | Meeting | Basic | Primary Ciliary Dyskinesia
KOL-Index: 28 BACKGROUND: Endobronchial biopsies are an important tool for the study of airway remodeling in children. We aimed to evaluate the impact of performing endobronchial biopsies as a part of fiberoptic bronchoscopy on the length of the procedure. METHODS: Clinically indicated fiberoptic bronchoscopy at which endobronchial biopsy was attempted as a part of a research protocol was performed in 40 ...
Known for
Children Fiberoptic | Airway Remodeling | Bronchoscopy Endobronchial | Macroscopically Adequate Biopsies
KOL-Index: 28 Primary ciliary dyskinesia (PCD) has been considered a relatively mild disease, especially compared to cystic fibrosis (CF), but studies on lung function in PCD patients have been few and small.This study compared lung function from spirometry of PCD patients to normal reference values and to published data from CF patients. We calculated z-scores and % predicted values for forced expiratory ...
Known for
66 | 65-68 | -93 | 6-9 Years

Royal Brompton & Harefield NHS Foundation Trust, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK

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