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    • Andrew G Frantz
    • Andrew G Frantz

      Andrew G Frantz

      Department of Medicine, Columbia University College of Physicians & Surgeons New York, NY 10032, USA | Department of Medicine, Columbia University College of Physicians and ...



      KOL Resume for Andrew G Frantz


      Department of Medicine, Columbia University College of Physicians & Surgeons New York, NY 10032, USA


      Department of Obstetrics and Gynecology, Cornell University Medical College, New York, New York


      Columbia College of Physicians and Surgeons, New York, New York 10032, U.S.A.

      Laboratory of the Biology of Addictive Disease, The Rockefeller University, New York, New York 10021, USA


      Departments of Medicine, St. Luke s-Roosevelt Hospital Center, and Columbia University College of Physicians and Surgeons, New York, New York


      Columbia University College of Physicians and Surgeons, USA


      Institute for Reproductive Sciences and Departments of Obstetrics and Gynecology, Neurosurgery, Medicine and Physiology, Columbia University, College of Physicians and Surgeons, New York, N.Y.


      Department of Neurological Surgery, Medicine, and Otolaryngology, Colubia University College of Physicians and Surgeons and Colubia‐Presbyterian Medical Center, New York, NY

      State University of New York at Stony Brook, Stony Brook, New York, USA


      New York, New York USA


      From the Departments of Urology and Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA


      Associate Professor, Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, N.Y.

      the Presbyterian Hospital, New York, N. Y., USA


      Department of Medicinie, Columbia College of Physicians and Surgeons, and Presbyterian Hospital, New York 10032


      Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, N. Y. USA


      Department of Medicine, Columbia University, College of Physicians & Surgeons, New York 10032


      Trainee, Institute of Arthritis and Metabolism, National Institutes of Health; now on active duty, U. S. Navy.



      Andrew G Frantz: Influence Statistics

      Sample of concepts for which Andrew G Frantz is among the top experts in the world.
      Concept World rank
      prolactin human blood #1
      neuroleptics prolactin response #1
      subjects prolactin responses #1
      chlorpromazine single doses #1
      exertion radioimmunoassay #1
      rats opioid pathway #1
      prolactin response neuroleptics #1
      male prolactin rhythm #1
      neurophysin development #1
      level serum prolactin #1
      6βohcortisol human urine #1
      laboratory additional references #1
      primary intrasellar tumor #1
      amniotic fluid hpl #1
      hours thioridazine #1
      prolactin studied #1
      separate human prolactin #1
      cent base #1
      secreting adenoma prolactin #1
      trh subjects #1
      obstetric endorphins #1
      stimulated prolactin values #1
      pituitary tumor suspects #1
      prolactin secretion chapter #1
      serum abortion #1
      variety intracranial diseases #1
      midtrimester elective abortion #1
      l3c dihydroxyphenylalanine #1
      prolactin secretion hours #1
      chapter dihydroxyphenylalanine humans #1
      reasons clear indication #1
      galactorrhea amenorrhea #1
      griffiths raiti #1
      initiating stimulus development #1
      catecholamines phenothiazines #1
      betaendorphin pituitary function #1
      antiserum naloxone #1
      tuberoinfundibular tract increases #1
      intrinsic prolactin activity #1
      phenothiazines studies #1
      opioid peptides article #1
      205 patients variety #1
      betaendorphin animal rats #1
      nipple stimulation baseline #1
      ldopa serum prolactin #1
      reports trh #1
      chlorpromazine concentrate #1
      animal prolactin physiology #1
      increased release sleep #1


      Prominent publications by Andrew G Frantz

      KOL-Index: 8881

      Prolactin has been measured in unextracted human plasma by a sensitive and specific in vitro bioassay. Secretory activity of breast tissue fragments from mid-pregnant mice, incubated in organ culture with human plasma, serves as the histologic end point. Sensitivity is 5 ng/ml (0.14 mU/ml) or somewhat better for ovine prolactin, and approximately 0.42 mU/ml for prolactin activity of human plasma at the dilutions used in the assay. Human growth hormone as it circulates in blood, like the ...

      Known for Human Prolactin | Growth Hormone | Organ Culture | Vitro Bioassay | Large Amounts
      KOL-Index: 8584

      An analysis of 235 patients with galactorrhea (5.5 per cent males) showed that 20 per cent of all patients, and 34 per cent of women with associated amenorrhea, had radiologically evident pituitary tumors; these patients had the highest serum prolactin concentrations. The largest single group (32 per cent) consisted of women with idiopathic galactorrhea without amenorrhea; prolactin was normal in 86 per cent of these cases. Five patients had the empty-sella syndrome. Prolactin response ...

      Known for Pituitary Tumors | Cent Patients | Galactorrhea Amenorrhea | Thyrotropinreleasing Hormone | Prolactin Response
      KOL-Index: 7326

      Corticotropin releasing factor immunoactivity (CRFi) has been identified in the plasma of women in the second half of gestation. There are several lines of evidence supporting a placental source for this hormone. Regulation of placental CRFi is poorly understood. In this study, the effect of a long-acting glucorticoid on the release of placental CRFi was investigated. Eleven women in the third trimester of pregnancy had plasma samples measured for CRFi, ACTH and cortisol before and after ...

      Known for Acth Cortisol | Releasing Factor | Maternal Plasma | Hormone Betamethasone | Trimester Pregnancy
      KOL-Index: 6792

      The prolactin response to neuroleptics can serve as an index of dopamine blockade in humans. Plasma prolactin increments to single doses of chlorpromazine, and prolactin decrements to single doses of levodopa, were similar in normal and schizophrenic subjects. Antischizophrenic drugs of all chemical classes stimulated prolactin release,while chemically related drugs and other psychotropic agents ineffective in schizophrenia did not. The prolactin response to neuroleptic therapy occurred ...

      Known for Prolactin Response | Schizophrenic Subjects | Haloperidol Humans | Dopamine Schizophrenia | Neuroleptic Dose
      KOL-Index: 6597

      Brain β-endorphin was measured by radioimmunoassay in female rats during different stages of the estrous cycle, during pregnancy, 3 weeks after ovariectomy, and 3 weeks after ovariectomy plus estradiol or estradiol and progesterone replacement. No change in hypothalamic β-endorphin content was noted on the afternoon of diestrus, proestrus, or estrus. However, in 9 rats studied between days 8–20 of pregnancy the mean hypothalamic β-endorphin concentration of41.6 ± 2.24ng/mg protein was ...

      Known for Estradiol Progesterone | Sex Steroids | Β Endorphin | 3 Weeks | Ovariectomized Rats
      KOL-Index: 6048

      alpha-MSH and beta-endorphin, both synthesized from a common precursor, have opposite behavioral actions. In order to determine if these peptides have opposite effects on pituitary function, basal LH secretion and basal and stress-induced prolactin release were studied in adult male rats after intraventricular injection of alpha-MSH. Each rat also received intraventricular saline in order to serve as its own control. 18 micrograms alpha-MSH stimulated plasma LH from 16.5 +/- 2.5 (SEM) ...

      Known for Alpha Msh | Stimulating Hormone | Prolactin Release | Male Rats | Stress Induced
      KOL-Index: 6032

      Previous studies have shown alterations of neuroendocrine function in humans receiving any narcotic on short-term basis or short-acting narcotics on a chronic basis. In this study of 16 well-stabilized patients, it was demonstrated that normalization of hypothalamic-pituitary-adrenal axis function, as reflected by normal levels and normal circadian rhythm of levels of beta-endorphin, ACTH and cortisol, is achieved during long-term steady state methadone maintenance treatment of former ...

      Known for Circadian Rhythms | Methadone Maintenance | Acth Cortisol | Heroin Dependence Humans | Chronic Basis

      Key People For Prolactin Secretion

      Top KOLs in the world
      Samuel McDonald McCann
      nitric oxide growth hormone prolactin release
      Nira Ben‐Jonathan
      posterior pituitary breast cancer estrogen receptor
      Joseph Meites
      male rats serum prolactin mammary tumors
      Robert M MacLeod
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      John C PORTER
      tyrosine hydroxylase pituitary gland releasing hormone
      Henry G Friesen
      growth hormone placental lactogen prolactin secretion

      Andrew G Frantz:Expert Impact

      Concepts for whichAndrew G Frantzhas direct influence:Prolactin secretion,  Growth hormone,  Human prolactin,  Hypophyseal portal blood,  Maternal serum,  Portal blood,  Plasma prolactin,  Serum prolactin.

      Andrew G Frantz:KOL impact

      Concepts related to the work of other authors for whichfor which Andrew G Frantz has influence:Growth hormone,  Prolactin secretion,  Menstrual cycle,  Pituitary gland,  Beta endorphin,  Plasma levels,  Median eminence.



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      Department of Medicine, Columbia University College of Physicians & Surgeons New York, NY 10032, USA | Department of Medicine, Columbia University College of Physicians and Surgeons New York, N.Y. 10032, USA | Department of Obstetrics and Gynecology,

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