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    • Curtis Alvin Pettaway
    • Curtis Alvin Pettaway: Influence Statistics

      Curtis Alvin Pettaway

      Curtis Alvin Pettaway

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      University of Texas MD Anderson Cancer Center, Houston, TX; | The University of Texas MD Anderson Cancer Center, Houston, TX, USA | Division of Surgery, Department of Urology, ...

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      Curtis Alvin Pettaway:Expert Impact

      Concepts for whichCurtis Alvin Pettawayhas direct influence:Prostate cancer,Penile cancer,Radical prostatectomy,African ancestry,Vascular invasion,Lymph node,Prostate cancer development,Nude mice.

      Curtis Alvin Pettaway:KOL impact

      Concepts related to the work of other authors for whichfor which Curtis Alvin Pettaway has influence:Prostate cancer,Radical cystectomy,Lymph node,Active surveillance,Tumor cells,Prostatic neoplasms,Cell carcinoma.

      KOL Resume for Curtis Alvin Pettaway

      Year
      2022

      University of Texas MD Anderson Cancer Center, Houston, TX;

      2021

      Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

      The University of Texas MD Anderson Cancer Center, Houston, Texas.

      2020

      University of Texas MD Anderson Cancer Center, Houston, TX, USA

      Department of Urology.

      UT MD Anderson Cancer Center, Houston, TX;

      2019

      Department of Urology, M.D. Anderson Cancer Center, University of Texas, Houston, TX, USA

      MD Anderson Cancer Center, Houston, TX

      2018

      Department of Urology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

      2017

      The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA

      Veda N. Giri, Karen E. Knudsen, William K. Kelly, Robert B. Den, Adam P. Dicker, Jean Hoffman-Censits, Mark D. Hurwitz, Colette Hyatt, Grace Lu-Yao, Mark J. Mann, James R. Mark, Peter A. McCue, Ronald E. Myers, Stephen C. Peiper, Edouard J. Trabulsi, and Leonard G. Gomella, Jefferson Sidney Kimmel Cancer Center; Justin E. Bekelman, University of Pennsylvania Perelman School of Medicine; S. Bruce Malkowicz, University of Pennsylvania; Elias Obeid and Robert Uzzo, Fox Chase Cancer Center; Gordon F....

      Department of Urology, MD Anderson Cancer Center, Houston, TX

      2016

      Department of Urology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

      2015

      The University of Texas, MD Anderson Cancer Center, Houston, TX, USA

      2014

      Department of Urology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1373, 77030, Houston, TX, USA

      The University of Texas M.D. Anderson Cancer Center, United States.

      2013

      Department of Urology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1373, 77030, Houston, TX, USA

      2012

      Professor and Director of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland

      Department of Urology, The University of Texas, MD Anderson Cancer Center, Houston, Texas

      University of Puerto Rico (VCL)

      2011

      Department of Urology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America

      University of Texas M. D. Anderson Cancer Center, Houston, TX

      Urology, M. D. Anderson Cancer Center, Houston, Texas

      2010

      From The University of Texas M. D. Anderson Cancer Center, Houston, TX.

      M.D. Anderson Cancer Center, University of Texas, Houston, Texas, USA

      2009

      Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston, Texas

      2008

      Department of Urology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas

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      Sample of concepts for which Curtis Alvin Pettaway is among the top experts in the world.
      Concept World rank
      male neoplasm rna #1
      patients penile melanoma #1
      palliative dissections incidence #1
      metastatic pc3m #1
      adequate dissection conclusion #1
      husbands observation #1
      prophylactic compared #1
      ahr ene #1
      wle bilnd #1
      dnr tumors #1
      ln3 cells #1
      diagnostic ilnd #1
      hgf pc3m #1
      inguinal node metastasis #1
      penile urethral involvement #1
      333 median followup #1
      egfrtargeted therapy patients #1
      lncap ln3 #1
      experience rail #1
      patients impalpable disease #1
      metastatic penile cancer #1
      mcsconclusionsthese findings #1
      clinical n3 disease #1
      signatures pscc #1
      10q21 q22 #1
      genomics paramount #1
      amputative surgery nrcss #1
      penile cancer chapter #1
      obvious secondary cancer #1
      102 113929 #1
      mutational signatures pscc #1
      surgical consolidation survival #1
      ilnd lymphedema lymphocele #1
      contemporary series morbidity #1
      soluble upa protein #1
      favorable outcomes management #1
      inguinal region patients #1
      verylowrisk pca #1
      mapping biopsy treatment #1
      hormonal therapy experience #1
      dnr transfection #1
      bilnd 3 #1
      bcl2 ln3 cells #1
      suspected inguinal metastases #1
      tests inguinal canal #1
      80–100 risk #1
      aam genomics #1
      greater treatment regret #1
      cohort sizes studies #1
      pscc samples #1
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      Prominent publications by Curtis Alvin Pettaway

      KOL-Index: 15432

      PURPOSE: We assessed whether dutasteride enhances the usefulness of total prostate specific antigen for diagnosing clinically significant prostate cancer.

      MATERIALS AND METHODS: The 4-year REDUCE study evaluated the efficacy and safety of 0.5 mg dutasteride daily for prostate cancer risk reduction in men with a prostate specific antigen of 2.5 to 10.0 ng/ml and a negative prostate biopsy. Specificity, sensitivity, and positive and negative predictive values of prostate specific antigen ...

      Known for Prostate Specific Antigen | Reduce Study | Negative Biopsy | Dutasteride Placebo | Gleason Score
      KOL-Index: 14782

      We investigated the role of transforming growth factor-beta (TGF-beta) signaling in the growth and metastasis of PC-3MM2 human prostate cancer cells. Highly metastatic PC-3MM2 human prostate cancer cells were engineered to constitutively overexpress a dominant-negative type II TGF-beta receptor (DNR). Transfection of DNR had minimal direct effects on cell growth and attenuated TGF-beta-induced cell growth inhibition and TGF-beta1 production. There were no discernable differences in ...

      Known for Growth Factor | Nude Mice | Pc3mm2 Cells | Prostate Cancer | Messenger Receptor
      KOL-Index: 14369

      Central obesity, measured by waist circumference (WC) or waist-hip ratio (WHR), is a marker of body fat distribution. Although obesity disproportionately affects minority populations, few studies have conducted genome-wide association study (GWAS) of fat distribution among those of predominantly African ancestry (AA). We performed GWAS of WC and WHR, adjusted and unadjusted for BMI, in up to 33,591 and 27,350 AA individuals, respectively. We identified loci associated with fat ...

      Known for Fat Distribution | African Ancestry | New Loci | Wc Whr | Genome Wide
      KOL-Index: 14329

      PURPOSE: We identified a subset of patients with bladder cancer (transitional cell carcinoma) and regional nodal metastasis to the retroperitoneal lymph nodes without detectable systemic dissemination. While the majority of these patients respond initially to chemotherapy, most have disease relapse at the same site within a year. We report the results of a phase II study exploring the potential benefit of retroperitoneal lymph node dissection in patients with transitional cell carcinoma ...

      Known for Retroperitoneal Lymph | Transitional Cell Carcinoma | Bladder Patients | Node Dissection | Response Chemotherapy
      KOL-Index: 13709

      PURPOSE: Inguinal lymphadenectomy can be curative in patients with small volume inguinal metastases and those with more significant adenopathy responding to combination chemotherapy. However, several series collected for 15 to 40 years attest to the significant morbidity associated with lymphadenectomy. We reviewed our recent experience with lymphadenectomy in patients with invasive penile cancer who were judged to require inguinal staging and therapeutic procedures to assess the ...

      Known for Lymphadenectomy Patients | Squamous Cell | Major Complications | Contemporary Morbidity | Cancer Center
      KOL-Index: 13273

      Since the NF-κB/relA transcription factor is constitutively activated in human prostate cancer cells, we determined whether blocking NF-κB/relA activity in human prostate cancer cells affected their angiogenesis, growth, and metastasis in an orthotopic nude mouse model. Highly metastatic PC-3M human prostate cancer cells were transfected with a mutated IκBα (IκBαM), which blocks NF-κB activity. Parental (PC-3M), control vector-transfected (PC-3M-Neo), and IκBαM-transfected (PC-3M–IκBαM) ...

      Known for Κb Activity | Human Prostate | Inbred Balb Mice | Cancer Cells | Angiogenesis Invasion
      KOL-Index: 13204

      OBJECTIVES: To determine if dutasteride-treated men can be monitored safely and adequately for prostate cancer based on data from the Reduction by Dutasteride in Prostate Cancer Events (REDUCE) study. To analyse whether the use of treatment-specific criteria for repeat biopsy maintains the usefulness of prostate-specific antigen (PSA) level for detecting high grade cancers.

      PATIENTS AND METHODS: The REDUCE study was a randomized, double-blind, placebo-controlled investigation of whether ...

      Known for Prostate Cancer Dutasteride | Reduce Study | Specific Antigen | Placebo Gleason | 10 Cancer
      KOL-Index: 12823

      PURPOSE: We compared the relationship of pathological features and preoperative prostate specific antigen (PSA) levels of a consecutive series of black patients to a stage matched cohort of white patients treated during the same period.

      MATERIALS AND METHODS: The radical prostatectomy specimens of 40 black patients were reviewed and tumor volume was determined. Histopathological features (stage, grade, zonal distribution of cancer foci), tumor volume and prostate weight were correlated ...

      Known for Prostate Specific | White Patients | Pathological Features | Tumor Volume | Psa Levels
      KOL-Index: 12709

      PURPOSE: Orthotopic bladder reconstruction in women is the focus of considerable interest. To define suitable candidates for orthotopic reconstruction among women with bladder cancer, we reviewed the risk of secondary urethral, vaginal and cervical involvement by transitional cell carcinoma in patients who underwent radical cystectomy at our institution.

      MATERIALS AND METHODS: We retrospectively reviewed the charts of women who underwent radical cystectomy for primary transitional cell ...

      Known for Radical Cystectomy | Bladder Cancer | Cell Carcinoma | Orthotopic Reconstruction | Urethral Neoplasms
      KOL-Index: 12297

      The purpose of this study was to determine whether the expression level of several metastasis-regulating genes correlates with the metastatic potential of human prostate cancer cells implanted into the prostate of nude mice. The steady-state mRNA expression levels for epidermal growth factor receptor (EGFR; growth), basic fibroblast growth factor (bFGF) and interleukin (IL)-8 (angiogenesis), 72-kd and 92-kd type IV collagenase (invasion), E-cadherin (adhesion), and multidrug resistance ...

      Known for Nude Mice | Gene Expression | Metastatic Potential | Human Prostate | Carcinoma Cells
      KOL-Index: 12295

      PURPOSE: We assessed the value of lymph node density for predicting disease specific survival after lymphadenectomy for penile cancer.

      MATERIALS AND METHODS: Data were collected retrospectively in 75 and prospectively in 88 consecutive patients with squamous cell carcinoma of the penis treated at M. D. Anderson Cancer Center between 1979 and 2007. We identified 45 patients with penile cancer and nodal metastasis who underwent lymphadenectomy with curative intent. Lymph node density was ...

      Known for Lymph Node Density | Penile Cancer | Specific Survival | Squamous Cell Humans | Nodal Metastasis

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      University of Texas MD Anderson Cancer Center, Houston, TX; | The University of Texas MD Anderson Cancer Center, Houston, TX, USA | Division of Surgery, Department of Urology, The University of Texas MD Anderson Cancer Center, Houston | Department of

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