• Disease
  • Arcus
  • Arcus Senilis
  • J Stevens Andrews

    Prominent publications by J Stevens Andrews

    KOL Index score: 3193

    A recent report1 on the pathology and histochemistry of arcus senilis emphasized the lipid nature of the corneal deposits and suggested that an understanding of arcus formation might explain some of the factors involved in fat deposition in other nonadipose tissues of the body.Although these investigators identified the components of arcus as probably a cholesterol derivative with some associated phospholipid and glyceride, the values obtained were necessarily only semiquantitative, and ...

    Also Ranks for: Arcus Senilis |  cornea corneal |  humans lipids
    KOL Index score: 1110

    1.1. Incubation of rabbit cornea in a sodium oleate-serum mixture was found by silicic acid chromatography of the extracted lipid to increase markedly the triglyceride content of this tissue. In the presence of 7 μmoles of sodium oleate per ml of serum the cornea was observed to synthesize triglyceride at the rate of approx. 10 μmoles/g of wet tissue/48 h.2.2. Use of sodium [I-14C]oleate and [14C6]glucose established these compounds as precursors in this synthetic process. An isotope ...

    Also Ranks for: Rabbit Cornea |  lipid metabolism
    KOL Index score: 271

    Interocular protein transfer was demonstrated after intravitreal injection of isotopically labeled bovine serum albumin into one eye of rabbits. The transfer of the trace molecule occurs by a nonhematogenous pathway. These experiments indicate that cerebrospinal fluid route and/or the ipsilateral optic nerve-chiasm-contralateral optic nerve are probably not the pathway mediating nonhematogenous interocular protein transfer.

    Also Ranks for: Optic Nerve


    J Stevens Andrews: Influence Statistics

    Sample of concepts for which J Stevens Andrews is among the top experts in the world.
    Concept World rank
    minor components lack #1
    components arcus #1
    arcus senilis quantities #1
    lipids arcus senilis #1
    arcus formation factors #1
    observed arcus purpose #1
    definitive histochemical test #1
    cornea arcus #1
    observed arcus #1
    arcus senilis report1 #1
    lipids arcus #3
    arcus formation #4
    cornea fatty #8
    cholesterol derivative phospholipid #8
    senilis cornea #10
    quantities minor #11
    minor fashion #18
    cornea rate #21
    principal lipid components #29
    arcus senilis #54

    Key People For Arcus Senilis

    Top KOLs in the world
    Toichiro Kuwabara
    electron microscopy retinal vascular patterns pigment epithelium
    David G Cogan
    intraocular melanoma retinal vascular patterns dysplastic nevus syndrome
    J Stevens Andrews
    arcus senilis lipid analysis rabbit cornea
    Basil M Rifkind
    hdl cholesterol coronary heart disease plasma lipids
    Stanley Marion Garn
    serum cholesterol tooth size sexual dimorphism
    Menard M Gertler
    serum cholesterol coronary heart disease antithrombin iii

    J Stevens Andrews:Expert Impact

    Concepts for whichJ Stevens Andrewshas direct influence:Arcus senilis,  Human cornea,  Rabbit cornea,  Lipid analysis,  Components arcus,  Arcus formation,  Minor fashion,  Abnormal quantities.

    J Stevens Andrews:KOL impact

    Concepts related to the work of other authors for whichfor which J Stevens Andrews has influence:Corneal arcus,  Limbal cornea,  Flurbiprofen sodium,  Cholesterol esters,  Tissue lipids,  Human atherosclerosis,  Aging sclera.



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    Howe Laboratory of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Mass. U.S.A.