• Pseudomembranous Colitis
    • Jin Heon Lee
    • Jin Heon Lee: Influence Statistics

      Jin Heon Lee

      Jin Heon Lee

      Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Sungnae-gil, Kangdong-gu, Seoul, Republic of Korea 134-701. | ...

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      Jin Heon Lee:Expert Impact

      Concepts for whichJin Heon Leehas direct influence:Pseudomembranous colitis,Pylori infection,Ischemic colitis,Chronic hepatitis,South korea,Hepatocellular carcinoma,Early hbeag seroconversion,Cardia cancer.

      Jin Heon Lee:KOL impact

      Concepts related to the work of other authors for whichfor which Jin Heon Lee has influence:Gastric cancer,Hepatocellular carcinoma,Chronic hepatitis,Ischemic colitis,Helicobacter pylori,Alcohol withdrawal,Hbv infection.

      KOL Resume for Jin Heon Lee


      Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Sungnae-gil, Kangdong-gu, Seoul, Republic of Korea 134-701.


      Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul,


      Seung In Seo, Hyoung Su Kim, Won Jin Kim, Woon Geon Shin, Kyung Ho Kim, Myoung Kuk Jang, Jin Heon Lee, Hak Yang Kim, Dong Joon Kim, Myung Seok Lee, Choong Kee Park, Department of Internal Medicine, Hallym University Medical Center, Seoul 134-701, South Korea.


      Department of Internal Medicine, Hallym University Medical Center, Seoul, Korea.


      Department of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.


      Department of Internal Medicine, Kangdong Sacred Heart Hospital of Hallym University Medical Center, Seoul, Republic of Korea


      Department of Internal Medicine


      Department of Internal Medicine, and


      Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University Medical Center, 445 Kildong, Kangdong‐gu, Seoul, South Korea, 134‐701


      Hallym University Medical Center, Seoul, South Korea


      Department of Internal Medicine,


      Division of Gastroenterology, Department of Internal Medicine; Kangdong Sacred Heart Hospital, Hallym University Medical Center, 445, Kildong, Kangdong-gu, Seoul 134-701, South Korea


      Division of Gastroenterology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea


      Department of Internal Medicine, Hallym University Medical Center, Seoul, ROK

      Sample of concepts for which Jin Heon Lee is among the top experts in the world.
      Concept World rank
      chb consecutively #3
      hdv korea #4
      032 korea #4
      hdv 032 #4
      global hdv infection #4
      hdv inactive #4
      korea hdv #4
      korea hbv infection #4
      31 195 subjects #4
      hbeagpositive chb genotype #5
      nonvertical transmission 95 #5
      early hepatitis antigen #5
      il1b511 genotype genotype #6
      mortality pseudomembranous colitis #6
      il1rn il2 #6
      duodenal ulcers addition #6
      increased levels2 #6
      hospital acquired diarrhea #6
      immune inactive chb #6
      122 gc #6
      levels2 uln #6
      gc duodenal ulcers #6
      clostridioides korea #6
      il1b511 31 gene #6
      levels2 uln followup #6
      330 gene #6
      116 gu #6
      interleukin disease humans #6
      prevalence pmc #6
      gc korean patients #7
      cox21195 aa genotype #7
      cox2765 genotypes #7
      cox21195 gg #7
      interleukin‐2 genes #7
      kangdong sacred #7
      1195 gg #7
      cox2765 1195 genes #7
      frequencies cox21195 gg #7
      1195 aa #7
      risk cox2 polymorphisms #7
      cox21195aa genotype #7
      genotype diffuse #7
      diffusetype gc korea #7
      factors pseudomembranous #7
      cox21195 gg genotype #7
      diagnosis pivka #8
      18 31 subjects #8
      analysis nonvertical #9
      interleukin2 korea #9
      pedunculated hepatic hemangioma #9

      Prominent publications by Jin Heon Lee

      KOL-Index: 14230

      Antibody to hepatitis B surface antigen (HBsAg) (anti-HBs) can exist in patients with chronic hepatitis B virus (HBV) infection. To date, little is known about the association of concurrent HBsAg and anti-HBs (concurrent HBsAg/ anti-HBs) with hepatocellular carcinoma (HCC). The aim of this study was to investigate the clinical relevance of concurrent HBsAg/anti-HBs with preS deletion mutations and HCC in chronic HBV infection. A total of 755 patients with chronic HBV infection were ...

      Known for Hepatocellular Carcinoma | Chronic Hepatitis | Hbsag Hcc | Virus Infection | Anti Hbs
      KOL-Index: 13779

      AIM: To determine the cutoff values and to compare the diagnostic role of alpha-fetoprotein (AFP) and prothrombin induced by vitamin K absence-II (PIVKA-II) in chronic hepatitis B (CHB).

      METHODS: A total of 1255 patients with CHB, including 157 patients with hepatocellular carcinoma (HCC), 879 with non-cirrhotic CHB and 219 with cirrhosis without HCC, were retrospectively enrolled. The areas under the receiver operating characteristic (AUROC) curves of PIVKA-II, AFP and their combination ...

      Known for Pivkaii Afp | Hepatocellular Carcinoma | Hcc Patients | Liver Cirrhosis | Hepatitis Chb
      KOL-Index: 12588

      BACKGROUND & AIMS: This study aimed to identify the predictors for early hepatitis B e antigen (HBeAg) seroconversion following acute exacerbation (AE) in patients with HBeAg-positive chronic hepatitis B (CHB).

      METHODS: A total of 151 patients with HBeAg-positive CHB and AE were consecutively enrolled. AE was defined as an elevation of alanine aminotransferase level to more than 5 times the upper limit of normal and more than twice the patients' baseline value. Early HBeAg seroconversion ...

      Known for Early Hbeag Seroconversion | Acute Exacerbation | Chronic Hepatitis | Patients Hbeag | Nonvertical Transmission
      KOL-Index: 11930

      Hepatitis D virus (HDV) infection can cause severe acute and chronic liver disease in patients infected with hepatitis B virus (HBV). Despite the significant decline in the global HDV infection, it remains a major health concern in some countries. This study aimed to investigate the prevalence and clinical features of HDV co-infection in patients with chronic HBV infection in Korea, where HBV infection is endemic. Nine hundred forty patients [median age, 48 (18-94) years; men, 64.5%] ...

      Known for Chronic Hepatitis | Patients Hdv | Hbv Infection | Delta Virus | Hepatocellular Carcinoma
      KOL-Index: 10770

      OBJECTIVE: To investigate the prevalence of occult HBV infection among subjects with normal serum ALT levels in South Korea.

      METHODS: A total of 195 serum samples were collected from subjects without a past history of alcohol abuse and with normal serum ALT levels. They were negative for HBsAg, anti-HCV, and anti-HIV. HBV-DNA was detected from sera by nested polymerase chain reaction (PCR) using specific primers of the surface antigen region of the HBV genome. We performed a quantitation ...

      Known for Occult Hbv Infection | South Korea | Hbv Dna | Specific Primers | Meticulous Attention
      KOL-Index: 10441

      BACKGROUND/AIM: Alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) are most widely used tumor markers in detecting hepatocellular carcinoma (HCC). Recently, there have been some studies about them as prognostic markers in hepatitis C virus-associated HCC. However, prognostic values of AFP and PIVKA-II remain clarified in hepatitis B virus (HBV)-associated HCC. This study was aimed to evaluate the prognostic values of AFP and PIVKA-II in ...

      Known for Hepatocellular Carcinoma | Afp Pivkaii | Prognostic Values | Liver Neoplasms | Protein Induced
      KOL-Index: 8503

      BACKGROUND AND AIM: Interleukin (IL)-1 gene polymorphism has been reported to be associated with the increment of gastric cancer (GC) and the decrement of duodenal ulcers (DU). In addition, IL-2 is known to induce Helicobacter pylori (H. pylori)-associated gastric atrophy, but it is not known whether IL-2 gene polymorphism increases the risk of GC (GC) or peptic ulcer diseases. Therefore, we compared the genotypes of IL-1B, IL-1RN, and IL-2 gene polymorphisms with risk of gastric ulcers ...

      Known for Gastric Cancer | Gene Polymorphism | Korean Patients | Disease Humans Interleukin | Helicobacter Pylori
      KOL-Index: 8028

      Clevudine is a nucleoside analog with an unnatural beta-L configuration. In a phase I/II clinical trial, once daily doses ranging from 10 to 200 mg for 28 days were well tolerated, and produced significant antiviral activity. The present study was conducted to assess the degree and durability of the antiviral response to 12 weeks of clevudine treatment, and to investigate its safety and tolerability. A total of 98 patients with HBeAg-positive chronic hepatitis B were randomized to ...

      Known for Antiviral Activity | Clevudine Therapy | 12 Weeks | Chronic Hepatitis | Clinical Trial
      KOL-Index: 6843

      We performed this study to determine the role of polymorphisms of the IL-10 and TNF-alpha promoter genes in the carcinogenesis/pathogenesis of gastric cancer (GC) and peptic ulcer diseases (PUD) in Korea. A total of 232 patients with gastric diseases and 120 healthy controls were included. Polymorphisms of IL-10-1082/-592 gene and TNF-A-308 gene were genotyped by PCR-RFLP. There were no differences in genotypes and allele frequencies of IL-10 and TNF-A polymorphism between study group ...

      Known for Gastric Cancer | Polymorphism Il10 | Genotypic Frequencies | Gc Korea | Tnf Alpha
      KOL-Index: 6196

      BACKGROUND: We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea.

      METHODS: 603,375, 639,465, 621,476, 612,705 and 650,398 serum samples were annually tested for HBsAg. Of HBsAg positive persons whose serum samples were available, HBeAg positivity was checked.

      RESULTS: HBsAg positivities among subjects between 6 and 19 years old were 8.2%, 3.9%, 2.1%, 2.6% and 1.3%. HBsAg positivities ...

      Known for South Korea | Hbv Infection | Hbsag Positivity | Late 1990s | Positive Rates
      KOL-Index: 6111

      PURPOSE: Pseudomembranous colitis is a severe form of antibiotic-associated diarrhea. However, there have been no reports about the factors that make patients with presumed antibiotic-associated diarrhea susceptible to pseudomembranous colitis. This study was designed to determine the clinical risk factors for pseudomembranous colitis among the patients with presumed antibiotic-associated diarrhea.

      METHODS: This was a retrospective study of 150 consecutive patients admitted to our ...

      Known for Pseudomembranous Colitis | Antibiotic Diarrhea | Multivariate Analysis | Clinical Risk Factors | Clostridioides Difficile
      KOL-Index: 5994

      BACKGROUND: The eradication rate of Helicobacter pylori (H. pylori) infection might be affected by the degree of inflammation of gastric mucosa represented by the endoscopic stage of peptic ulcer disease (PUD). The aims of this study were to evaluate the eradication rates of H. pylori infection according to the endoscopic stage of PUD and to document whether early eradication in the active stage could yield a higher eradication rate in patients with peptic ulcer bleeding (PUB).

      MATERIALS ...

      Known for Eradication Rate | Helicobacter Pylori | Peptic Ulcer | Proton Pump | Anti Bacterial
      KOL-Index: 5322

      PURPOSE: This study was performed to find clinical risk factors for developing ischemic colitis in patients experiencing lower abdominal discomfort with or without bloody diarrhea.

      METHODS: A total of 467 patients who underwent sigmoidoscopy or colonoscopy because of lower abdominal discomforts with or without blood in stool were consecutively enrolled; 147 patients were diagnosed endoscopically and histologically as having ischemic colitis. The control group was composed of the ...

      Known for Ischemic Colitis | Abdominal Pain | 67 Patients | Adjusted Odds Ratio | Bloody Diarrhea
      KOL-Index: 5278

      BACKGROUND/AIMS: The tumor-node-metastasis (TNM) staging is an useful system to assess the prognosis of any solid cancer. As new TNM staging classification of 7th stomach cancer was revised in 2009, we evaluated the prognostic predictability of the 7th International Union Against Cancer/American Joint Committee on Cancer (UICC/AJCC) TNM classification compared to 6th UICC/AJCC TNM classification in gastric cancer.

      METHODS: From January 2000 to December 2009, 5-year survival rates of 266 ...

      Known for Gastric Cancer | 7th Edition | Joint Committee | Tnm Classification | Neoplasm Staging

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      Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, 150, Sungnae-gil, Kangdong-gu, Seoul, Republic of Korea 134-701. | Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym Univers

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