• KOL
    • Harry Roger Büller
    • Harry Roger Büller

      Harry Roger Büller

      Department of Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands | From KU Leuven Department of Cardiovascular ...

       

       

      CV Kol pour Harry Roger Büller

      Year
      2022

      Department of Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands

      2021

      From KU Leuven Department of Cardiovascular Sciences, Vascular Medicine and Hemostasis, Leuven, Belgium (P.V.); Anthos Therapeutics, Cambridge, MA (B.A.Y., J.S., D.B.); International Trial Expertise Advisory and Services (A.S.) and the Department of Vascular Medicine, Academic Medical Center, University of Amsterdam (H.R.B.) - both in Amsterdam; Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City (G.E.R.); and the Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON, Canada (J.I.W.).

      Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands (H.R.B.).

      2020

      From the Faculty of Medical Sciences, State University of Groningen, Groningen, the Netherlands (M.O.); Department of Vascular Medicine, Amsterdam University Medical Centre, Amsterdam, the Netherlands (H.R.B., N.V.Es.); Department of Radiology, Haaglanden Medical Centre, The Hague, the Netherlands (D.K.); Department of Radiology, Nederlands Kanker Instituut, Amsterdam, the Netherlands (S.F.O.); Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, U.S.A. (T.M.); Department of Intensive Care Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands (D.G.); 7. National Institute of Public Health, Ministry of Health, Bilthoven, the Netherlands (J.V.D.); Department of Vascular Medicine, Maastricht University, Maastricht, the Netherlands (H.T.C.); Edinburgh Imaging, Queens Medical Research Institute, University of Edinburgh, Edinburgh, U.K.(E.J.R.V.B.)

      Department of Vascular Medicine, Amsterdam University Medical Center, Amsterdam, The Netherlands

      2019

      Department of Vascular Medicine, Academic Medical Center, Universiteit van Amsterdam, Amsterdam, The Netherlands.

      Dept of Vascular Medicine, Amsterdam Cardiovascular Science, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

      2018

      Department of Vascular Medicine, Academic Medical Centre Amsterdam, University of Amsterdam, Amsterdam, Netherlands

      2017

      Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, AZ, Amsterdam, The Netherlands.

      From Academic Medical Center and Slotervaartziekenhuis, Amsterdam, the Netherlands; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Université de Bretagne Occidentale, Brest, France; Hospital of Padua, Padua, Italy; Clinica Universidad de Navarra, Pamplona, Spain; Virgen del Rocio Hospital, Seville, Spain; Karolinska Institutet, Stockholm, Sweden; Warsaw Medical University, Warsaw, Poland; Centre Hospitalo-Universitaire Estaing, Clermont-Ferrand, France; University of Utah, Salt Lake City, Utah; University Hospital Leuven, Leuven, Belgium; and University G. D'Annunzio, Chieti-Pescara, Italy.

      2016

      Center for Experimental and Molecular Medicine, Amsterdam Medical Center, Amsterdam, The Netherlands

      2015

      Academic Medical Center University of Amsterdam Department of Vascular Medicine Amsterdam the Netherlands

      2014

      From the College of Public Health, University of Oklahoma Health Sciences Center (G.E.R., M.M., A.W.); Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand (P.A.); División Hemostasia, Academia Nacional de Medicina, Buenos Aires, Argentina (A.N.B.); Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands (H.B.); SA Pathology–Department of Hematology, Flinders Medical Center, Adelaide, South Australia, Australia (A.G.); Thrombosis and Thrombophilia Centre, Guy’s & St Thomas’ NHS Foundation Trust, London, United Kingdom (B.J.H.); Boston University School of Medicine, MA (E.M.H.); Thrombosis Research Institute, London, United Kingdom (A.K.); Center for Thrombosis and Hemostasis, Johannes Gutenberg University, Mainz, Germany (S.V.K.); Department of Laboratory Medicine, University of Yamanashi, Tamaho, Yamanashi, Japan (Y.O.); and McMaster University and Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (J.I.W.).

      Department of General Practice, Academic Medical Centre, University of Amsterdam, Amsterdam and

      2013

      Department of Vascular Medicine, F4-140, Academic Medical Centre, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands

      Academic Medical Center, Amsterdam (H.R.B.)

      2012

      Academic Medical Center, Department of Vascular Medicine, Amsterdam (H.R.B.)

      Vascular Medicine, AMC, Amsterdam, the Netherlands

      2011

      Internal Medicine, Academic Medical Center, Amsterdam, Netherlands,

      From the Academic Medical Center

      and Slotervaart Hospital, Amsterdam

       

       

      Harry Roger Büller: Statistiques d'influence

      Échantillon de concepts pour lesquels Harry Roger Büller est parmi les meilleurs experts du monde.
      Concept World rank
      probability cdr #1
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      loss subsequent pregnancy #1
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      3 rfviia #1
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      0·2 3633 patients #1
      patients protein deficiencies #1
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      elevated fviii #1
      idraparinux recurrent thromboembolism #1
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      ctscanreading #1
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      3633 patients edoxabantreated #1
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      prophylaxis idraparinux #1
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      patients idraparinux #1
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      heparin vitamin antagonist #1
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      sgs pretest probability #1
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      rnapc2 groups placebo #1
      lowmolecularweight heparin category #1
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      3 idraparinux #1
      rnapc2 inhibition #1
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      cancer patients uedvt #1
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      standard treatment idraparinux #1
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      current practise #1
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      major bleeds vka #1
      enoxaparin vkas #1
      longhaul flight #1
      compression ultrasonography presentation #1
      dimer result #1
      vitamin antagonists treatment #1
      abdominal pelvic strategies #1
      combination cdr #1
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      pulmonary embolism #1
      patients normal tests #1
      ventricular dysfunction edoxaban #1
      750 μg l1 #1
      95 intracranial #1
      rabinov #1
      cdr ddimer levels #1
      chest perfusion scan #1
      intravenous injections lmwh #1
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      clinical uedvt #1
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      ankle brachial prevalence #1
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      pulmonary embolism role #1
      ultrasonography dvt #1
      aged venous #1
      carriers pulmonary embolism #1
      patients acute recurrent #1
      method factor #1
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      lmwh departments #1
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      enoxaparin vkas treatment #1
      uesvt uedvt #1
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      normal venogram #1
      fetal loss carriers #1
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      conventional therapy enoxaparin #1
      cancer patients ufh #1
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      tomography angiography vte #1
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      abnormal vaginal bleeding #1
      fviii homocysteine #1
      anticoagulant treatment vte #1
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      easier monitoring #1
      edoxaban dalteparin #1
      neoplasms heparin #1
      postthrombotic symptoms patients #1
      vte risk coc #1
      acute recurrent patients #1
      feasibility venography #1
      dalteparin vte treatment #1
      reocclusion antithrombotic drug #1
      extended treatment edoxaban #1
      vte trial #1
      probability lung scan #1
      venous thromboembolism idraparinux #1
      incidental symptomatic vte #1
      death venous thromboembolism #1
      lmwh immobilization #1
      outcome clinically #1
      dose response apixaban #1
      low levels ft4 #1
      anticoagulants probability #1
      rule exclusion #1
      patients tb402 #1
      presence venous thrombosis #1
      intestinal microbiota coagulation #1
      studies 3 months #1
      failure cip #1
      venous thrombosis hyperglycemia #1
      mortality postthrombotic symptoms #1
      atherosclerosis hemophilia patients #1
      reduceddose noacs #1
      false normal #1
      tests pulmonary embolism #1
      controlledstudy #1
      560 pharmacies #1
      acute treatment lmwh #1
      36 papers #1
      vte arterial #1
      respondents lmwh #1
      category perelated death #1
      dvt costs #1
      thiazoles venous #1
      ft4 level patients #1
      heparin vitamin #1
      combination cdrscore #1
      fetal loss stillbirth #1
      patients examiner #1
      fxainhibitors vka recipients #1
      compression ultrasound dvt #1
      patients advanced prostate #1
      cdrs patients #1
      randomized studies efficacy #1
      enoxaparin warfarin antiplatelet #1
      idraparinux vte #1
      heparins data #1
      age∗10μg #1
      thromboembolism 3 #1
      warfarin cancer patients #1
      prothrombin individuals #1
      presenting location vte #1
      included patients study #1
      failure rate efficiency #1
      death vte studies #1
      messages justification #1
      presentation major #1
      antidote vitamin #1
      deep vein thrombosis #1
      leg ultrasonography patients #1
      mutation arg506 #1
      thrombosis vitamin #1
      pulmonary embolism idraparinux #1
      synthetic selective factor #1
      elevated fviii age #1
      phase doacs #1
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      avidin idrabiotaparinux #1
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      wells cdr #1
      clinically suspected uedvt #1
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      idraparinux 25 #1
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      embolism suspected #1
      hokusai‐vte cancer study #1
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      venous thrombosis mutations #1
      heparins cancer spread #1
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      association protein levels #1
      rfviia idraparinux #1
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      efficacy vte #1
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      idraparinux placebo #1
      cip diagnostic management #1
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      lmwh edoxaban #1
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      initial treatment patients #1
      survival fondaparinux #1
      excluding pulmonary #1
      20210a mutation #1
      patients ivte #1
      proximal extent ipe #1
      topic thrombophlebitis #1
      vka netherlands #1
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      intracranial clinical presentation #1
      heparin survival #1
      venous thrombus growth #1
      hokusai vte cancer #1
      ultrasonography diagnostic #1
      superficial thrombophlebitis incidence #1
      qscan #1
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      2630 pilots #1
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      matisse dvt #1
      patients retropubic prostatectomy #1
      year prophylaxis #1
      rivaroxaban replacement #1
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      older patients cdr #1
      doacs cirrhosis patients #1
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      idraparinux 6 months #1
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      standard therapy rivaroxaban #1
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      vte fatal #1
      category fxainhibitors #1
      placebo 25mg apixaban #1
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      simple diagnostic strategy #1
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      pulmonary embolism metaanalysis #1
      treatment venous #1
      3633 patients edoxaban #1
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      ldfr symptomatic legs #1
      clinical probability patients #1
      carriers relative risks #1
      respondents 60 #1
      lmwh delivery #1
      presentation category #1
      combined training gps #1
      scores occult cancer #1
      heparins vitamin antagonists #1
      normohomocysteinemic relatives hyperhomocysteinaemia #1
      factor viii homocysteine #1
      uesvt mortality #1
      dimer clinical #1
      qscan 3 weeks #1
      relatives antithrombin #1
      thrice daily gentamicin #1
      rabinovpaulin #1
      avws prevalence #1
      clinical probability risk #1
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      cancer 145 patients #1
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      coagulation fibrinolytic proteins #1
      decisions duration #1
      compression ultrasonography detection #1
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      wells clinical #1
      rhir lmwh #1
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      vitamin anticoagulants #1
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      control anticardiolipin antibodies #1
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      patients khorana #1
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      idrabiotaparinux idraparinux #1
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      dalteparin major bleeding #1
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      cancer patients patients #1
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      vte procoagulant activity #1
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      rivaroxaban lmwh vka #1
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      infections gentamicin #1
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      scan pulmonary embolism #1
      12 months edoxaban #1
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      fviii venous thromboembolism #1
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      isolated deficiencies proteins #1
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      clinically suspected dvt #1
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      previous surveys netherlands #1
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      ultrasonography leg veins #1
      apixaban extended treatment #1
      s1p1activation #1
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      leg veins patients #1
      embolism wells #1
      preferred oral anticoagulant #1
      women factor leiden #1
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      intrinsic coagulation vivo #1
      patency smokers #1
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      recurrence bleeding risk #1
      standalone ddimer testing #1
      wound haematoma #1
      severe presentation patients #1
      pulmonary embolism studies #1
      unexplained dvt #1
      orthopedic thromboprophylaxis #1
      normal ddimer result #1
      subcutaneous nadroparin placebo #1
      subsequent symptomatic cancer #1
      inr studies #1
      idraparinux patients #1
      patients deep #1
      svt lmwh #1
      relatives mutation #1
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      perelated death classification #1
      factor viii relatives #1
      impedance thrombophlebitis #1
      extensive screening cancer #1
      daily dalteparin treatment #1
      fviii hyperhomocysteinemia #1
      initial heparin patients #1
      pulmonary angiography strategies #1
      acquired atiii deficiency #1
      heparins inhibition #1
      chromogenic endotoxin #1
      97 compression ultrasonography #1
      diagnostic management patients #1
      cdr normal #1
      pioped study study #1
      hyperhomocysteinemia relatives #1
      idraparinux vitamin antagonist #1
      subsequent diagnosis malignancy #1
      nadroparin therapeutic dose #1
      silent dvt #1
      association travel #1
      wellscdr #1
      studies ttr #1
      doacs initial heparin #1
      suspected deep #1
      pulmonary embolism fondaparinux #1
      bmi fondaparinux #1
      standardintensity vkas #1
      undvt #1
      ventilation scan chest #1
      timeperiod #1
      tb402 enoxaparin #1
      practiceassistants #1
      plasma concentration fviii #1
      vte airline pilots #1
      pvo ctscan #1
      fxiaso enoxaparin #1
      patients clinical probability #1
      coagulation clinical #1
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      thrombo‐embolic events #1
      presenting location women #1
      initial heparin edoxaban #1
      initial treatment dvt #1
      patients unexplained dvt #1
      cancer cdr #1
      smoking graft patency #1
      heparinoid #1
      cdr dimer #1
      normal levels fviii #1
      departments orthopedic surgery #1
      revascularisation procedures patients #1
      cvc crt #1
      ml1 ctpa #1
      unexplained dvt patients #1
      fondaparinux unfractionated #1
      clinical decision rule #1
      0·2 edoxabantreated #1
      adjusted dose ufh #1
      united states rnapc2 #1
      strategies abdominal pelvic #1
      standardintensity vkas doacs #1
      378 patients edoxaban #1
      single dose tb402 #1
      women edoxaban #1
      tests venography #1
      rfviia fondaparinux #1
      matisse trials #1
      dvt anticoagulants #1
      constans score #1
      relative risks carriers #1
      quantitative ddimer testing #1
      perelated death category #1
      ventilation lung scanning #1
      hokusaivte trial patients #1
      milliliter enoxaparin #1
      wells rules #1
      enoxaparin initial treatment #1
      pyridines recurrence #1
      controlled trials thrombophilia #1
      presentation 1 week #1
      noncarriers annual incidence #1
      recurrent vte immobilization #1
      cdrscore #1
      cstatistic major bleeding #1
      procoagulant factors levels #1
      9 incidence #1
      efficacy conventional treatment #1
      quantitative dimer #1
      p0001 saline #1
      early time recurrence #1
      predefined outcomes #1
      sspe proximal #1
      edoxaban risk factors #1
      elderly patients dvt #1
      models development studies #1
      enoxaparin primary efficacy #1
      pulmonary embolism cdr #1
      idraparinux versus #1
      positive vte #1
      death category #1
      casedescription #1
      ccus 4 #1
      specificity pulmonary embolism #1
      followup overt cancer #1
      studies doac treatment #1
      early discharge strategies #1
      strategy abdominal pelvic #1
      tsh antitpo #1
      einsteinextension #1
      wells simplified #1
      acenocoumarol initial treatment #1
      cus strategies #1
      lowmolecularweight heparin treatment #1
      250 patients cancer #1
      crp test patients #1
      fxainhibitors #1
      elderly outpatients combination #1
      iii plg #1
      oral anticoagulants phase #1
      idraparinux #1
      perfusion scan #1
      nondiagnostic lung scan #1
      obstetric complications relatives #1
      incidence venous #1
      flebography #1
      endotoxemia tests #1
      clinical probability exclusion #1
      edoxaban cancer patients #1
      patients mismatched scan #1
      cancer patients cdr #1
      fviii women #1
      vte risk day #1
      combination nonhigh cdr #1
      anticoagulant treatment patients #1
      probability categories #1
      elevated biomarkers hospital #1
      platelets iqr #1
      exclusion pulmonary #1
      clinically relevant disease #1
      falsenormal #1
      subcutaneous length life #1
      simplified geneva score #1
      guideline adherence justification #1
      lowmolecularweight heparin 95 #1
      ddimer result #1
      category death #1
      screening carriers #1
      extended anticoagulation doacs #1
      patients tests prevalence #1
      double reports #1
      apixaban conventional therapy #1
      lmwh users incidence #1
      cancer patients cancer #1
      withheld #1
      months standard therapy #1
      patients reduceddose noacs #1
      outcome recurrent #1
      netherlands vka #1
      ifngamma pselectin #1
      acenocoumarol heparin #1
      botticelli dvt dose‐ranging #1
      heparin initial treatment #1
      placebo rnapc2 #1
      15 lmwh #1
      acenocoumarol therapy acenocoumarol #1
      xainhibitors #1
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      5392 #23
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      #28
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      thromboembolism warfarin #30
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      costs diagnosis #30
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      f1 2 #30
      xii factor #30
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      2 antiplasmin #31
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      30 #3649
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      network meta #3746
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      525 #3791
      412 #3795
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      life illness #3801
      333 #3802
      versus #3803
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      preexisting #3808
      outcome measure #3814
      330 #3815
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      iu #3818
      55 patients #3821
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      197 #3849
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      4 patients #3858
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      death #3880
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      cancer survival #3884
      record #3885
      sensitivity #3885
      avoids #3887
      calculated #3888
      difference #3890
      351 #3890
      184 #3890
      10000 #3902
      methylamines #3903
      halflives #3903
      methimazole #3904
      patients time #3905
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      angiography #3915
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      coronary thrombosis #3918
      decide #3927
      474 #3931
      ankle #3932
      955 #3935
      458 #3938
      jak2 #3939
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      405 #3946
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      neurology #3953
      56 #3956
      p004 #3961
      dichotomy #3961
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      women #3964
      carboxypeptidases #3965
      postoperatively #3966
      clinical effectiveness #3968
      uncontrolled #3970
      risk cancer #3970
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      Prominent publications by Harry Roger Büller

      KOL-Index: 23031

      BACKGROUND:  Guidelines addressing the management of venous thromboembolism (VTE) in cancer patients are heterogeneous and their implementation has been suboptimal worldwide.

      OBJECTIVES: To establish a common international consensus addressing practical, clinically relevant questions in this setting.

      METHODS: An international consensus working group of experts was set up to develop guidelines according to an evidence-based medicine approach, using the GRADE system.

      RESULTS: For the ...

      Connu pour Vte Patients | Venous Thromboembolism | Prophylaxis Lmwh | 3 Months | Practice Guidelines
      KOL-Index: 20177

      OBJECTIVES: The objective of this study was to compare the predictive performance of bleeding risk-estimation tools in a cohort of patients with atrial fibrillation (AF) undergoing anticoagulation.

      BACKGROUND: Three bleeding risk-prediction schemes have been derived for and validated in patients with AF: HEMORR(2)HAGES (Hepatic or Renal Disease, Ethanol Abuse, Malignancy, Older Age, Reduced Platelet Count or Function, Re-Bleeding, Hypertension, Anemia, Genetic Factors, Excessive Fall ...

      Connu pour Atrial Fibrillation | Bled Bleeding | Hemorr2hages Atria | Intracranial Hemorrhage | Topic Risk
      KOL-Index: 17342

      This chapter about antithrombotic therapy for venous thromboembolic disease is part of the seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do, or do not, outweigh risks, burden, and costs. Grade 2 suggests that individual patients' values may lead to different choices (for a full understanding of the grading see Guyatt et al, CHEST 2004; 126:179S-187S). Among the key ...

      Connu pour Antithrombotic Therapy | Grade 1a | Venous Thromboembolic Disease | Vka Lmwh | Inr Range
      KOL-Index: 16684

      PURPOSE: Initial heparinization followed by vitamin K antagonists is the treatment of choice for patients with venous thromboembolism. There is controversy whether known malignancy is a risk factor for recurrences and bleeding complications during this treatment. Furthermore, the incidence of such events in these patients is dependent on the achieved International Normalized Ratio (INR). The aim of this study was to assess the incidence of venous thromboembolic recurrence and major ...

      Connu pour Venous Thromboembolism | Bleeding Complications | Patients Malignancy | Retrospective Analysis | International Normalized
      KOL-Index: 16378

      BACKGROUND: Venous thromboembolism occurs commonly in patients with cancer. Direct oral anticoagulants are non-inferior to conventional anticoagulants for the treatment of venous thromboembolism. We hypothesised that edoxaban, a direct oral inhibitor of activated clotting factor Xa, might be more suitable than conventional anticoagulants in the management of cancer-associated venous thromboembolism. The aim of this study was to assess the efficacy and safety of edoxaban compared with ...

      Connu pour Venous Thromboembolism | Patients Cancer | Hazard Ratio | Clinically Relevant Bleeding | Factor Inhibitors
      KOL-Index: 15975

      BACKGROUND: Whether the oral factor Xa inhibitor edoxaban can be an alternative to warfarin in patients with venous thromboembolism is unclear.

      METHODS: In a randomized, double-blind, noninferiority study, we randomly assigned patients with acute venous thromboembolism, who had initially received heparin, to receive edoxaban at a dose of 60 mg once daily, or 30 mg once daily (e.g., in the case of patients with creatinine clearance of 30 to 50 ml per minute or a body weight below 60 kg), ...

      Connu pour Warfarin Patients | Hazard Ratio | Venous Thromboembolism | Pulmonary Embolism | Primary Efficacy Outcome
      KOL-Index: 15905

      ESSENTIALS: Cancer patients are at high risk of venous thromboembolism (VTE). In this study, cases and controls were cancer patients who did or did not develop VTE. von Willebrand factor (VWF) levels were higher if compared with controls and correlated with cancer stage. VWF and ADAMTS-13 are associated with the occurrence of VTE in cancer.

      BACKGROUND: Patients with cancer are at high risk of venous thromboembolism (VTE). ADAMTS-13 regulates von Willebrand factor (VWF) activity, which ...

      Connu pour Willebrand Factor | Venous Thromboembolism | Vte Cancer | Vwf Adamts13 | Khorana Score
      KOL-Index: 15571

      BACKGROUND: Rivaroxaban, an oral factor Xa inhibitor, may provide a simple, fixed-dose regimen for treating acute deep-vein thrombosis (DVT) and for continued treatment, without the need for laboratory monitoring.

      METHODS: We conducted an open-label, randomized, event-driven, noninferiority study that compared oral rivaroxaban alone (15 mg twice daily for 3 weeks, followed by 20 mg once daily) with subcutaneous enoxaparin followed by a vitamin K antagonist (either warfarin or ...

      Connu pour Oral Rivaroxaban | Venous Thromboembolism | Vitamin Antagonist | Continued Treatment | Hazard Ratio
      KOL-Index: 15512

      BACKGROUND: After hip replacement surgery, prophylaxis following discharge from hospital is recommended to reduce the risk of venous thromboembolism. Our aim was to assess the oral, direct thrombin inhibitor dabigatran etexilate for such prophylaxis.

      METHODS: In this double-blind study, we randomised 3494 patients undergoing total hip replacement to treatment for 28-35 days with dabigatran etexilate 220 mg (n=1157) or 150 mg (1174) once daily, starting with a half-dose 1-4 h after ...

      Connu pour Hip Replacement | Dabigatran Enoxaparin | Venous Thromboembolism | Etexilate Versus | Primary Efficacy Outcome
      KOL-Index: 15505

      CONTEXT: Previous studies have evaluated the safety of relatively complex combinations of clinical decision rules and diagnostic tests in patients with suspected pulmonary embolism.

      OBJECTIVE: To assess the clinical effectiveness of a simplified algorithm using a dichotomized clinical decision rule, D-dimer testing, and computed tomography (CT) in patients with suspected pulmonary embolism.

      DESIGN, SETTING, AND PATIENTS: Prospective cohort study of consecutive patients with clinically ...

      Connu pour Pulmonary Embolism | Computed Tomography | Dimer Testing | Patients Suspected | 3 Months
      KOL-Index: 15415

      BACKGROUND: Dabigatran etexilate is an oral direct thrombin inhibitor undergoing evaluation for the prevention of venous thromboembolism (VTE) following orthopedic surgery.

      METHODS: In a multicenter, parallel-group, double-blind study, 1973 patients undergoing total hip or knee replacement were randomized to 6-10 days of oral dabigatran etexilate (50, 150 mg twice daily, 300 mg once daily, 225 mg twice daily), starting 1-4 h after surgery, or subcutaneous enoxaparin (40 mg once daily) ...

      Connu pour Total Hip | Dabigatran Etexilate | Thromboembolic Events | Knee Replacement | Vte Patients
      KOL-Index: 14849

      BACKGROUND: Oral anticoagulants, such as dabigatran etexilate, an oral, direct thrombin inhibitor, that do not require monitoring or dose adjustment offer potential for prophylaxis against venous thromboembolism (VTE) after total knee replacement surgery.

      METHODS: In this randomized, double-blind study, 2076 patients undergoing total knee replacement received dabigatran etexilate, 150 mg or 220 mg once-daily, starting with a half-dose 1-4 hours after surgery, or subcutaneous enoxaparin ...

      Connu pour Subcutaneous Enoxaparin | Oral Dabigatran | Total Knee Replacement | Venous Thromboembolism | Prevention Vte
      KOL-Index: 14797

      BACKGROUND: The standard initial treatment of hemodynamically stable patients with pulmonary embolism is intravenous unfractionated heparin, requiring laboratory monitoring and hospitalization.

      METHODS: We conducted a randomized, open-label trial involving 2213 patients with acute symptomatic pulmonary embolism to compare the efficacy and safety of the synthetic antithrombotic agent fondaparinux with those of unfractionated heparin and to document noninferiority in terms of efficacy. ...

      Connu pour Unfractionated Heparin | Pulmonary Embolism | Initial Treatment | Subcutaneous Fondaparinux | Intravenous Injections
      KOL-Index: 14727

      OBJECTIVES: To determine the rate of a first recurrent venous thromboembolism (VTE) event after discontinuation of anticoagulant treatment in patients with a first episode of unprovoked VTE, and the cumulative incidence for recurrent VTE up to 10 years.

      DESIGN: Systematic review and meta-analysis.

      DATA SOURCES: Medline, Embase, and the Cochrane Central Register of Controlled Trials (from inception to 15 March 2019).

      STUDY SELECTION: Randomised controlled trials and prospective cohort ...

      Connu pour Anticoagulant Treatment | Recurrent Vte | Unprovoked Venous | 10 Years | 95 Confidence Interval

      Des personnes clés pour Pulmonary Embolism

      Top Kols dans le monde
      #1
      Samuel Zachary Goldhaber
      pulmonary embolism atrial fibrillation major bleeding
      #2
      Henri M Bounameaux
      pulmonary embolism deep vein thrombosis clinical probability
      #3
      Harry Roger Büller
      pulmonary embolism venous thrombosis major bleeding
      #4
      Menno V Huisman
      pulmonary embolism atrial fibrillation major bleeding
      #5
      Paul D Stein
      pulmonary embolism deep venous thrombosis aortic valve
      #6
      Philip Stephen Wells
      pulmonary embolism major bleeding deep vein thrombosis

      Harry Roger Büller:Impact expert

      Concepts pour lesquelsHarry Roger Büllera une influence directe:Pulmonary embolism,  Venous thromboembolism,  Venous thrombosis,  Major bleeding,  Deep vein thrombosis,  Atrial fibrillation,  Vein thrombosis.

      Harry Roger Büller:Impact de Kol

      Concepts liés au travail d'autres auteurs pour lesquelsfor which Harry Roger Büller a une influence:Venous thromboembolism,  Pulmonary embolism,  Atrial fibrillation,  Deep vein thrombosis,  Oral anticoagulants,  Major bleeding,  Vte patients.


       

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      Department of Medicine, Amsterdam University Medical Center, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands | From KU Leuven Department of Cardiovascular Sciences, Vascular Medicine and Hemostasis, Leuven, Belgium (P.V.); Anthos Therap

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