Prominent publications by Joel Brian Epstein

KOL Index score: 18397

BACKGROUND: Multiple oral complaints develop during radiation therapy for head and neck cancer, and quality of life is affected after treatment. The purpose of this investigation was to assess the quality of life, oral function, and oral symptoms in a cohort of patients during and after radiation therapy.

METHODS: A general quality of life survey (the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLQ-C30), with an added oral symptom and ...

Known for Radiation Therapy |  Oral Function |  Quality Life |  Neck Cancer |  Female Head
KOL Index score: 13963

BACKGROUND: Epidermal growth factor (EGF) is present in biologic fluids, including saliva, and plays a role in maintenance of the epithelial barrier and in healing of damaged mucosa. The purpose of this study was to assess the relation between salivary EGF and the severity of oral mucositis in patients with carcinoma of the head and neck during radiation therapy.

METHODS: Whole resting saliva (WRS) and whole stimulated saliva (WSS) were collected prior to radiation and each week during ...

Known for Radiation Therapy |  Oral Mucositis |  Growth Factor |  Stimulated Saliva |  Head Neck
KOL Index score: 13322

Multiple oral complaints develop following high-dose chemo/radiotherapy and hematopoietic cell transplantation (HCT) which can influence quality of life. The purpose of this investigation was to assess quality of life, oral function, taste and smell in a cohort of patients following HCT. A general quality of life survey (the European Organization for Research and Treatment of Cancer (EORTC)) Quality of Life (QOL) questionnaire (QLQ-C30), with an added oral symptom and function scale and ...

Known for Life Taste |  Cell Transplantation |  Oral Function |  Patients Hct |  Allogeneic Hematopoietic
KOL Index score: 12689

BACKGROUND: Head and neck cancers are of particular interest to health care providers, their patients, and those paying for health care services, because they have a high morbidity, they are extremely expensive to treat, and of the survivors only 48% return to work. Consequently the economic burden of oral cavity, oral pharyngeal, and salivary gland cancer (OC/OP/SG) must be understood. The cost of these cancers in the U.S. has not been investigated.

METHODS: A retrospective analysis of ...

Known for Salivary Gland |  Commercial Insurance |  Oral Pharyngeal |  Cancers Patients |  Medicaid Medicare
KOL Index score: 12131

OBJECTIVES: Despite aggressive antifungal prophylaxis, the increased risk for systemic fungal infection in recipients of hematopoietic cell transplants (HCT) continues to be a significant concern because Candida infection can cause morbidity and mortality in these patients. The objectives of this study were to examine the relationship of oral colonization by Candida species to systemic infection, mortality, and the impact of antifungal treatment on a population of recipients of ...

Known for Oral Candidiasis |  Cell Transplantation |  Candida Patients |  Antifungal Agents |  Undergoing Hematopoietic
KOL Index score: 11673

OBJECTIVE: Oral cancer is primarily a disease of epithelial origin. The tongue is the most common site of oral cancer. Oropharyngeal cancer accounts for approximately 2% of all cancer deaths. The purpose of this study was to analyze a case series of patients with tongue cancer.

STUDY DESIGN: The medical records of 322 consecutive patients diagnosed with squamous cell carcinoma (SCC) of the tongue treated from 1979-1994 were reviewed.

RESULTS: Patients had a mean age of 61.1 years and a ...

Known for Oral Tongue |  Clinical Presentation |  Alcohol Drinking Carcinoma |  Patients Cancer |  Advanced Stage
KOL Index score: 11635

BACKGROUND: Multiple oral complaints occur following radiotherapy for oropharyngeal cancer, but the frequency and severity of symptoms of dysfunction and discomfort are not well understood. The purpose of this investigation was to assess the quality of life, oral function, and oral symptoms following radiotherapy.

METHODS: A general quality of life survey (the European Organization for Research and Treatment of Cancer [EORTC] Quality of Life Questionnaire QLQ-C30), with an added oral ...

Known for Oral Function |  Quality Life |  Female Head |  Neck Neoplasms Humans |  Dry Mouth
KOL Index score: 11279

BACKGROUND: Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis.

METHODS: A literature search was conducted to identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article was independently reviewed by 2 ...

Known for Cancer Therapy |  Clinical Practice Guidelines |  Published Criteria |  Mascc Isoo |  Hyperbaric Oxygenation
KOL Index score: 11270

Goals of workThis study sought to characterize the range of oral symptoms and affect upon quality of life reported by pediatric and adolescent patients in relation to the severity of oral mucositis and symptom burden during chemotherapy.Patients and methodsA multicenter study included 140 patients between 6 and 18 years of age who had been treated with chemotherapy. Participants completed the self-report Mouth and Throat Soreness-related Questions of the Oral Mucositis Daily ...

Known for Oral Mucositis |  Adolescent Patients |  Quality Life |  Undergoing Chemotherapy |  Selfreport Mouth
KOL Index score: 11148

PurposeThere is a large body of evidence supporting the efficacy of low-level laser therapy (LLLT), more recently termed photobiomodulation (PBM) for the management of oral mucositis (OM) in patients undergoing radiotherapy for head and neck cancer (HNC). Recent advances in PBM technology, together with a better understanding of mechanisms involved and dosimetric parameters may lead to the management of a broader range of complications associated with HNC treatment. This could enhance ...

Known for Chemoradiation Therapy |  Pbm Management |  Neck Cancer |  Level Laser |  Crt Patients
KOL Index score: 10653

OBJECTIVES: This study evaluated the utility (usefulness) of toluidine blue application as an aid to the recognition and diagnosis of clinically evident lesions in a series of patients previously treated for oral cancer and monitored in a cancer center. In addition to increased risk of recurrence of cancer or new second primary lesions, patients who have had previous treatment for oropharyngeal cancer may be more difficult to assess because of tissue changes that occur as a result of ...

Known for Toluidine Blue |  Diagnostic Aid |  Clinical Examination |  Local Neoplasms |  Patients Oral Cancer
KOL Index score: 10646

BACKGROUND: Results from studies conducted in the past several years suggest that some oropharyngeal cancers, those of the base of the tongue and the tonsils, are associated with high-risk types of human papillomavirus (HPV). In this article, the authors summarize the available evidence regarding the epidemiology of HPV-associated oropharyngeal cancers in the United States, the available HPV vaccines and the implications of these for dentistry. They also examine the differences in HPV ...

Known for United States |  Human Papillomavirus |  Oropharyngeal Cancers |  Squamous Cell |  Hpv Vaccines
KOL Index score: 10579

PURPOSE: The purpose of this study was to assess the value of sucralfate suspension in prevention of oral mucositis and for reduction of oral pain in patients who develop mucositis during radiation therapy.

METHODS AND MATERIALS: The study was a double-blind, placebo-controlled, randomized prospective trial of a sucralfate suspension in the prevention and management of oral mucositis during radiation therapy. Oral mucositis was assessed using a quantitative scale and symptoms were ...

Known for Radiation Therapy |  Oral Mucositis |  Sucralfate Suspension |  Quantitative Scale |  Pain Patients
KOL Index score: 10318

BACKGROUND: Lymphoma is the second most common neoplasm of the head and neck; almost 50% of all lymphomas occur in this region. Waldeyer's ring is the most common site of lymphomas involving the oral region. The purpose of this study was to review the characteristics of a large series of malignant lymphoma of the oral region.

METHODS: Three hundred sixty-one consecutive cases of malignant lymphoma of the oral region were identified in the Tumor Registry between 1969 and 1998.


Known for Malignant Lymphoma |  Oral Region |  Head Neck |  Lymphocytic Chronic |  Large Bcell


Joel Brian Epstein: Influence Statistics

Sample of concepts for which Joel Brian Epstein is among the top experts in the world.
Concept World rank
highrisk lesions carcinoma #1
regression treatment modality #1
management systemic azathioprine #1
patients fluoride gel #1
daily medications prescription #1
white oral lesions #1
photons composition #1
study cariogenic flora #1
oks proposal #1
radiation therapy xerostomia #1
female head lymphocytic #1
lichenoid mucosal #1
situ falsenegative findings #1
orofacial pain taste #1
hct relationship #1
orn dental extraction #1
analgesics management #1
prevention mucosal breakdown #1
tmd npc #1
erythroplakia erythroleukoplakia lesions #1
mirnas biopsy carcinoma #1
management pentoxifylline #1
relationship oral colonization #1
hairy leukoplakia cases #1
hcl oral #1
recipients xerostomia #1
mucositis reduction #1
radiation tooth loss #1
miconazole buccal #1
safety mbt #1
experiments 1 pbm #1
bethanechol cevimeline #1
tolonium chloride #1
proprietary topical #1
benzydamine hydrochloride rinse #1
osteoradionecrosis periodontal #1
tobacco usage lesions #1
mucosal anesthesia subjects #1
mucosal coating agents #1
prevention bon #1
efficacy bethanechol #1
topical doxepin rinse #1
visualization lesions #1
oral intake treatment #1
directors oral medicine #1
surgical resection preservation #1
serum oral il6 #1
placebo iseganan #1
xerostomia radiation therapy #1

Key People For Oral Mucositis

Top KOLs in the world
Stephen T Sonis
oral mucositis cancer therapy hematologic malignancies
Joel Brian Epstein
oral mucositis radiation therapy temporomandibular disorders
Douglas E Peterson
oral mucositis cancer therapy bone marrow
Mark M Schubert
host disease oral mucositis marrow transplantation
Linda S Elting
united states cancer survivors deep venous thrombosis
Dorothy M K Keefe
oral mucositis south australia breast cancer

Joel Brian Epstein:Expert Impact

Concepts for whichJoel Brian Epsteinhas direct influence:Oral mucositis,  Radiation therapy,  Cancer therapy,  Oral cancer,  Temporomandibular disorders,  Oral health,  Oral complications,  Neck cancer.

Joel Brian Epstein:KOL impact

Concepts related to the work of other authors for whichfor which Joel Brian Epstein has influence:Oral mucositis,  Neck cancer,  Radiation therapy,  Squamous cell,  Lichen planus,  Quality life,  Burning mouth syndrome.



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City of Hope Comprehensive Cancer Center, Duarte & Cedars Sinai Health System, Los Angeles, USA | Department of Dentistry, Cedars-Sinai Health System, Los Angeles, California, USA; Department of Dentistry, City of Hope Comprehensive Cancer Center, Du

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