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    • John P A Ioannidis
    • John P A Ioannidis: Influence Statistics

      John P A Ioannidis

      John P A Ioannidis

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      Departments of Medicine, of Epidemiology and Population Health, of Biomedical Data Science, and of Statistics, Stanford University, Stanford, CA, USA | Department of ...

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      John P A Ioannidis:Expert Impact

      Concepts for whichJohn P A Ioannidishas direct influence:Observational studies,Randomized controlled trials,Umbrella review,Major depression,Randomized controlled.

      John P A Ioannidis:KOL impact

      Concepts related to the work of other authors for whichfor which John P A Ioannidis has influence:Randomized controlled trials,Breast cancer,Physical activity,Observational studies,Systematic review metaanalysis,Network meta,Type 2 diabetes.

      KOL Resume for John P A Ioannidis

      Year
      2022

      Departments of Medicine, of Epidemiology and Population Health, of Biomedical Data Science, and of Statistics, Stanford University, Stanford, CA, USA

      Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, California

      Meta-Research Innovation Center Berlin (METRIC-B), QUEST Center for Responsible Research, Berlin Institute of Health at Charité, Berlin, Germany

      2021

      Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA

      Meta-Research Innovation Center Berlin (METRIC-B), QUEST Center for Transforming Biomedical Research, Berlin Institute of Health, Charité - Universitätsmedizin Berlin.

      Biomedical Data Science

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      Sample of concepts for which John P A Ioannidis is among the top experts in the world.
      Concept World rank
      ranked discovery datasets #1
      dose aerosolized pentamidine #1
      total fatalities countries #1
      external validation validation #1
      platforms peptide profiling #1
      statistical significance trials #1
      diagnostic accuracy simulations #1
      excess findings #1
      19 specialists #1
      switzerland greece #1
      ὠφελέειν #1
      biased studies #1
      promising basic #1
      biomedical humans #1
      gwa platforms #1
      buruli ulcer trials #1
      uspstf review #1
      meta analysis data #1
      quality science #1
      validation independent validation #1
      pragmatism trials #1
      478655 #1
      subsequent waves wave #1
      ucpbirths #1
      benefits metaanalysis #1
      locations corrected median #1
      afg3l1p #1
      hemagglutininationinhibition #1
      squared55 #1
      infection fatality #1
      mobility npis #1
      candidate gene gwass #1
      rs910873 #1
      rcdrct #1
      pcp 100 patients #1
      sars‐cov‐2 re‐infection risk #1
      model imperial college #1
      col11a1 association #1
      rs1805008mc1r #1
      datasets observational studies #1
      remission treated patients #1
      populations contribution #1
      highlycited #1
      non‐evidence‐based measures #1
      wellchina #1
      equor single studies #1
      subsequent metaanalyses #1
      readiness evidence #1
      estimates analyses #1
      recruitit—rationale #1
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      Prominent publications by John P A Ioannidis

      KOL-Index: 21884

      BACKGROUND: Major depressive disorder is one of the most common, burdensome, and costly psychiatric disorders worldwide in adults. Pharmacological and non-pharmacological treatments are available; however, because of inadequate resources, antidepressants are used more frequently than psychological interventions. Prescription of these agents should be informed by the best available evidence. Therefore, we aimed to update and expand our previous work to compare and rank antidepressants for ...

      Known for Acute Treatment | Major Depressive Disorder | Comparative Efficacy | Network Meta | Antidepressants Placebo
      KOL-Index: 21803

      BACKGROUND: Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the threshold of detection for two years or more. We investigated whether a less intensive maintenance regimen could sustain viral suppression after an initial response to combination therapy.

      METHODS: HIV-infected subjects who had CD4 cell counts greater than 200 per cubic millimeter, who had been treated with ...

      Known for Hiv Rna | Zidovudine Lamivudine | Viral Suppression | Drug Therapy | Subjects Indinavir
      KOL-Index: 19364

      BACKGROUND: Infants born at term by elective caesarean section are more likely to develop respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications.

      OBJECTIVES: The objective of this review was to assess the effect of prophylactic corticosteroid administration before elective caesarean section at term, as compared to usual management without ...

      Known for Respiratory Morbidity | Elective Caesarean | Placebo Treatment | Admission Neonatal Special | Administration Antenatal
      KOL-Index: 19297

      BACKGROUND: The design of randomised controlled trials (RCTs) should incorporate characteristics (such as concealment of randomised allocation and blinding of participants and personnel) that avoid biases resulting from lack of comparability of the intervention and control groups. Empirical evidence suggests that the absence of such characteristics leads to biased intervention effect estimates, but the findings of different studies are not consistent.

      OBJECTIVES: To examine the influence ...

      Known for 95 Cri | Randomised Controlled Trials | Trial Characteristics | Allocation Concealment | Intervention Estimates
      KOL-Index: 18191

      Objective To map the diverse health outcomes associated with serum uric acid (SUA) levels.Design Umbrella review.Data sources Medline, Embase, Cochrane Database of Systematic Reviews, and screening of citations and references.Eligibility criteria Systematic reviews and meta-analyses of observational studies that examined associations between SUA level and health outcomes, meta-analyses of randomised controlled trials that investigated health outcomes related to SUA lowering treatment, ...

      Known for Observational Studies | Health Outcomes | Mendelian Randomisation | Acid Levels | Systematic Reviews Metaanalyses
      KOL-Index: 17668

      BACKGROUND: There has been a long-standing debate regarding whether aminoglycosides should be administered on a multiple daily dosing (MDD) or once-daily dosing (ODD) schedule. Several unique characteristics of the aminoglycosides make ODD an attractive and possibly superior alternative to MDD. These include concentration-dependent bactericidal activity; postantibiotic effect, which allows continued efficacy even when serum concentrations fall below expected minimum inhibitory ...

      Known for Odd Mdd | Eligible Studies | Rates Ototoxicity | Risk Ratio | Efficacy Toxicity
      KOL-Index: 17321

      Importance: Dietary modification remains key to successful weight loss. Yet, no one dietary strategy is consistently superior to others for the general population. Previous research suggests genotype or insulin-glucose dynamics may modify the effects of diets.

      Objective: To determine the effect of a healthy low-fat (HLF) diet vs a healthy low-carbohydrate (HLC) diet on weight change and if genotype pattern or insulin secretion are related to the dietary effects on weight loss.

      Design, ...

      Known for Weight Loss | Carbohydrate Diet | Insulin Secretion | Clinical Trial | 12 Months
      KOL-Index: 16964

      OBJECTIVE: To evaluate the breadth, validity, and presence of biases of the associations of vitamin D with diverse outcomes.

      DESIGN: Umbrella review of the evidence across systematic reviews and meta-analyses of observational studies of plasma 25-hydroxyvitamin D or 1,25-dihydroxyvitamin D concentrations and randomised controlled trials of vitamin D supplementation.

      DATA SOURCES: Medline, Embase, and screening of citations and references.

      ELIGIBILITY CRITERIA: Three types of studies were ...

      Known for Observational Studies | Umbrella Review | Randomised Trials | Supplementation Vitamin | Multiple Health Outcomes
      KOL-Index: 15389

      OBJECTIVE: Two previous individual participant data meta-analyses (IPDMAs) found that different diagnostic interviews classify different proportions of people as having major depression overall or by symptom levels. We compared the odds of major depression classification across diagnostic interviews among studies that administered the Depression subscale of the Hospital Anxiety and Depression Scale (HADS-D).

      METHODS: Data accrued for an IPDMA on HADS-D diagnostic accuracy were analysed. ...

      Known for Major Depression | Diagnostic Interviews | Hospital Anxiety | Scid Cidi | Participant Data
      KOL-Index: 15260

      BACKGROUND: Infants born at term by elective caesarean delivery are more likely to develop respiratory morbidity than infants born vaginally. Prophylactic corticosteroids in singleton preterm pregnancies accelerate lung maturation and reduce the incidence of respiratory complications.

      OBJECTIVES: The objective of this review was to assess the effect of prophylactic corticosteroid administration before elective caesarean section at term, as compared to usual management without ...

      Known for Respiratory Morbidity | Elective Caesarean | Prophylactic Administration Betamethasone | Newborn Intensive Units | Infants Term
      KOL-Index: 15112

      OBJECTIVE: GDF5 and FRZB have been proposed as genetic loci conferring susceptibility to osteoarthritis (OA); however, the results of several studies investigating the association of OA with the rs143383 polymorphism of the GDF5 gene or the rs7775 and rs288326 polymorphisms of the FRZB gene have been conflicting or inconclusive. To examine these associations, we performed a large-scale meta-analysis of individual-level data.

      METHODS: Fourteen teams contributed data on polymorphisms and ...

      Known for Knee Hip | Association Gdf5 | Aged Osteoarthritis | Rs7775 Frzb | Genetic Effects
      KOL-Index: 14900

      OBJECTIVE: To systematically examine the design, reporting standards, risk of bias, and claims of studies comparing the performance of diagnostic deep learning algorithms for medical imaging with that of expert clinicians.

      DESIGN: Systematic review.

      DATA SOURCES: Medline, Embase, Cochrane Central Register of Controlled Trials, and the World Health Organization trial registry from 2010 to June 2019.

      ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Randomised trial registrations and ...

      Known for Reporting Standards | Deep Learning | Risk Bias | Medical Imaging | Artificial Intelligence
      KOL-Index: 14644

      BACKGROUND: Regional and subtype-specific mutational patterns of HIV-1 transmitted drug resistance (TDR) are essential for informing first-line antiretroviral (ARV) therapy guidelines and designing diagnostic assays for use in regions where standard genotypic resistance testing is not affordable. We sought to understand the molecular epidemiology of TDR and to identify the HIV-1 drug-resistance mutations responsible for TDR in different regions and virus subtypes.

      METHODS AND FINDINGS: ...

      Known for Molecular Epidemiology | Resistance Tdr | Latin America Caribbean | North America | Hiv1 Drug

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      Departments of Medicine, of Epidemiology and Population Health, of Biomedical Data Science, and of Statistics, Stanford University, Stanford, CA, USA | Department of Biomedical Data Science, School of Medicine, Stanford University, Stanford, Californ

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