Diana Suárez‐Boomgaard: Influence Statistics

Diana Suárez‐Boomgaard

Diana Suárez‐Boomgaard

Facultad de Ciencias, Instituto de Investigación Biomédica, Universidad de Málaga, 29071 Málaga, Spain;, boomgaard83@gmail.com, (D.S.-B.);, ale_valde@uma.es, (A.V.-C.);, ...

Diana Suárez‐Boomgaard: Expert Impact

Concepts for which Diana Suárez‐Boomgaard has direct influence: Dopamine d4 receptor , Dopamine d4 , Rat caudate putamen , P2x7 receptors , Opioid receptor , D4 receptor , Dorsal striatum .

Diana Suárez‐Boomgaard: KOL impact

Concepts related to the work of other authors for which for which Diana Suárez‐Boomgaard has influence: P2x7 receptor , Purinergic signalling , Dopamine d4 , Opioid addiction , Microglial cells , Basal ganglia , Endogenous opiates .

KOL Resume for Diana Suárez‐Boomgaard

Year
2021

Facultad de Ciencias, Instituto de Investigación Biomédica, Universidad de Málaga, 29071 Málaga, Spain;, (D.S.-B.);, (A.V.-C.);, (K.S.);, (M.Á.R.)

2018

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Brussels, Belgium

2017

Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles

2016

Facultad de Ciencias Universidad de Málaga, Instituto de Investigación Biomédica Málaga Spain

2014

Université Libre de Bruxelles

Department of Cell Biology, School of Science, University of Málaga, 29071 Málaga, Spain; E-Mails:, (D.S.-B.);, (A.R.)

2013

School of Science, University of Málaga Department of Cell Biology Málaga Spain

2011

Department of Cell Biology, School of Science, University of Málaga, 29071 Málaga, Spain

2010

Department of Cell Biology, Faculty of Sciences, University of Malaga, 29071, Malaga, Spain

Prominent publications by Diana Suárez‐Boomgaard

KOL-Index: 10213 . Morphine is one of the most effective drugs used for pain management, but it is also highly addictive. Morphine elicits acute and long-term adaptive changes at cellular and molecular level in the brain, which play a critical role in the development of tolerance, dependence and addiction. Previous studies indicated that the dopamine D4 receptor (D4 R) activation counteracts morphine-induced ...
Known for Dopamine D4 | Spraguedawley Receptors | Caudate Putamen Cpu | Opioid Morphine
KOL-Index: 9875 . The mu opioid receptor (MOR) is critical in mediating morphine analgesia. However, prolonged exposure to morphine induces adaptive changes in this receptor leading to the development of tolerance and addiction. In the present work we have studied whether the continuous administration of morphine induces changes in MOR protein levels, its pharmacological profile, and MOR-mediated G-protein ...
Known for Dopamine D4 Receptor | Rat Caudate Putamen | Counteracts Morphine | Μ Opioid
KOL-Index: 9674 . Acute administration of the dopamine D(4) receptor (D(4)R) agonist PD168,077 induces a down-regulation of the μ opioid receptor (MOR) in the striosomal compartment of the rat caudate putamen (CPu), suggesting a striosomal D(4)R/MOR receptor interaction in line with their high co-distribution in this brain subregion. The present work was designed to explore if a D(4)R/MOR receptor ...
Known for Rat Caudate Putamen | Spraguedawley Receptors | Transcription Factors | Pd168077 Morphine
KOL-Index: 8163 . The peptides dynorphin and enkephalin modulate many physiological processes, such as motor activity and the control of mood and motivation. Their expression in the caudate putamen (CPu) is regulated by dopamine and opioid receptors. The current work was designed to explore the early effects of the acute activation of D4 and/or μ opioid receptors by the agonists PD168,077 and morphine, ...
Known for Caudate Putamen | Dopamine D4 | Spraguedawley Receptors | Messenger Rats
KOL-Index: 6553 . The role of the ATP-gated receptor, P2X7, has been evaluated in the unilateral 6-OHDA rat model of Parkinson’s disease using the P2X7 competitive antagonist A-438079. Nigral P2X7 immunoreactivity was mainly located in microglia but also in astroglia. A-438079 partially but significantly prevented the 6-OHDA-induced depletion of striatal DA stores. However, this was not associated with a ...
Known for P2x7 Receptors | Parkinson Disease | Receptor Antagonist | Rat Model
KOL-Index: 3055 . G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner. However, despite the current development of experimental techniques for large-scale detection of GPCR heteromers, in order to understand their connectivity ...
Known for Coupled Receptor | Gpcr Heteromers | Interaction Data | Models Molecular
KOL-Index: 725 . During the formation of a complex organism, cells divide, die, migrate, and differentiate. Biologists have established tools to observe those phenomena but also to change their course, which subsequently enables to infer causal relationships between various events occurring in different cell groups. More precisely, present approaches mostly rely on modifications of gene expression. For ...
Known for Fluorescent Proteins
KOL-Index: 338 . Receptor–receptor interactions that occur in G protein-coupled receptors (GPCRs) oligomers can be explored using three different functional approaches as starting point: (1) quantitative receptor autoradiography (saturation assay); (2) agonist-stimulated [35S]GTPγS binding in autoradiography; and (3) immunohistochemistry. Together, they allow to explore functional changes in receptors ...
Known for Opioid Mor | Protein Coupled
KOL-Index: 274 . During the formation of a complex organism, cells divide, die, migrate, and differentiate. Biologists have established tools to observe those phenomena but also to change their course, which subsequently enables to infer causal relationships between various events occurring in different cell groups. More precisely, present approaches mostly rely on modifications of gene expression. For ...
Known for Developmental Biology
KOL-Index: 246 . Long-term exposition to morphine elicits structural and synaptic plasticity in reward-related regions of the brain, playing a critical role in addiction. However, morphine-induced neuroadaptations in the dorsal striatum have been poorly studied despite its key function in drug-related habit learning. Here, we show that prolonged treatment with morphine triggered the retraction of the ...
Known for Opioid Receptors

Key People For Dopamine D4 Receptor

Top KOLs in the world
#1
Hubert H M Van Tol
dopamine receptors d4 receptor gene expression
#2
James R Bunzow
dopamine receptors adenylyl cyclase rat brain
#3
Hong‐Chang Guan
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#4
Philip Seeman
dopamine receptors antipsychotic drugs rat brain
#5
Olivier Civelli
dopamine receptors orphanin fq psychiatric disorders
#6
Hyman B Niznik
dopamine receptors d1 receptor rat brain

Facultad de Ciencias, Instituto de Investigación Biomédica, Universidad de Málaga, 29071 Málaga, Spain;, boomgaard83@gmail.com, (D.S.-B.);, ale_valde@uma.es, (A.V.-C.);, kirill@wustl.edu, (K.S.);, mar@uma.es, (M.Á.R.) | Institut de Recherche Interdis