• Disease
  • Rectal
  • Rectal Pouch
  • Alexander M Holschneider

    Prominent publications by Alexander M Holschneider

    KOL Index score: 11423

    BACKGROUND: Intestinal neuronal dysplasia (IND) of the colonic submucous plexus is considered to be a congenital malformation of the enteric nervous system causing symptoms resembling those of Hirschsprung's disease. In contrast with the established diagnosis of aganglionosis using enzyme histochemistry, controversy exists over the diagnostic criteria of IND on rectal biopsies previously defined by a consensus report and the causal relation between morphological findings and clinical ...

    Also Ranks for: Rectal Biopsy |  intestinal neuronal dysplasia |  interobserver variation |  hirschsprungs disease |  children diagnosis
    KOL Index score: 8034

    AIM: Although the literature on fundoplications in childhood is relatively extensive, only few reports exist which correlate the rate of complications with the primary disease. Other important questions such as the incidence of postoperative dumping syndrome or Barrett's esophagus in childhood are barely treated. Nor have operative techniques such as single or double-row cuff sutures or the benefit of performing pylorotomy or pyloroplasty in addition to fundoplication been investigated ...

    Also Ranks for: Esophageal Atresia |  reflux disease |  barretts esophagus |  dumping syndrome |  postoperative complications
    KOL Index score: 7683

    Hypoganglionosis of the myenteric plexus of the colon is not clearly defined and seldom investigated. Colon segments from 15 children with an extended oligoeuronal hypoganglionosis up to the proximal resection end were morphometrically studied and compared to normally innervated colon segments. The study was performed with resected specimens from 7 children with isolated hypoganglionoses, 8 children with a Hirschsprung-associated hypoganglionosis, and 12 colon segments with normal ...

    Also Ranks for: Myenteric Plexus |  hypoganglionosis colon |  chronic constipation |  morphometric measurements |  nerve cell
    KOL Index score: 7116

    PURPOSE: To examine the quality of life after repair of esophageal atresia, follow-up studies were performed in 58 of 71 surviving patients (81.7%).

    METHODS: Fifty patients with primary anastomosis and all eight surviving patients with colon interposition were seen. The mean age was 25.3 years (range, 20 to 31). Symptoms were evaluated by a standardized interview. Quality of life assessment was performed using a visual analogue scale (0 to 100 points), the Spitzer Index (5 dimensions, 10 ...

    Also Ranks for: Esophageal Atresia |  quality life |  primary anastomosis |  20 years |  follow studies
    KOL Index score: 6621

    The innervation patterns of the rectal pouch and fistula of 52 children with anorectal malformations were investigated. Posterior sagittal anorectoplasty was used for intermediate and high anomalies; for the latter it was combined with an abdominal approach. Perineoproctoplasty was performed for low anomalies. The specimens were investigated by acetylcholinesterase staining, lactate dehydrogenase, and succinyldehydrogenase reaction. They consisted of fistula material only in 23 patients ...

    Also Ranks for: Rectal Pouch |  severe constipation |  fistula rectum |  imperforate child |  intermediate anomalies
    KOL Index score: 6561

    Intestinal Dysganglionoses (IDs) represent a heterogeneous group of Enteric Nervous System anomalies including Hirschsprung's disease (HD), Intestinal Neuronal Dysplasia (IND), Internal Anal Sphincter Neurogenic Achalasia (IASNA) and Hypoganglionosis. At present HD is the only recognised clinico-pathological entity, whereas the others are not yet worldwide accepted and diagnosed. This report describes the areas of agreement and disagreement regarding definition, diagnosis, and management ...

    Also Ranks for: Hirschsprungs Disease |  enteric nervous |  intestinal dysganglionoses |  postoperative complications |  diagnostic workup
    KOL Index score: 5790

    The results of surgery for anorectal malformation (ARM) in 536 children treated between 1962 and 1993 are presented. Before 1985, patients underwent an abdominoperineal pullthrough for high and intermediate type of ARM, whereas cut-back procedures or perineoproctoplasty were performed in low type. Since 1985, we have changed our policy and performed a modified posterior sagittal anorectoplasty (PSARP) for intermediate type of ARM, eventually combined with an abdominal mobilization for ...

    Also Ranks for: Anorectal Malformations |  rectal pouch |  imperforate child child |  low type |  hirschsprung disease
    KOL Index score: 5591

    Abstract The objective of our study was to determine the efficacy of ventriculostomy as the primary treatment for posthemorrhagic hydrocephalus in premature infants. Within a period of 4 years, 20 very low birthweight (VLBW) infants (birthweight median 1135 g, range 650–1470 g) were treated for progressive posthemorrhagic hydrocephalus (PHHC) by right parietal ventriculostomy (Salmon Rickham) at a mean age of 21 days. Serial tapping of the subcutaneous reservoir was performed for ...

    Also Ranks for: Posthemorrhagic Hydrocephalus |  newborn infant |  permanent shunt |  low birth |  cerebrospinal fluid
    KOL Index score: 5237

    The authors present an overview of 101 patients operated for Hirschsprung's disease by Rehbein procedure. Special attention is directed to the histomorphological findings in the proximal segment of the resected bowel specimens. A strong link was confirmed between these specific features and postoperative bowel function. A histologically regular proximal bowel segment generally predicted good postoperative bowel function with a constipation rate of 10.5%. In patients with intestinal ...

    Also Ranks for: Proximal Segment |  resected bowel |  hirschsprung disease |  intestinal neuronal dysplasia |  predicts postoperative
    KOL Index score: 5090

    A prospective study of 141 consecutive patients with intestinal neuronal malformations is presented. The single malformation of the autonomic nervous system that always required surgical intervention was aganglionosis. Giant ganglia, reduced parasympathetic tone, immature ganglia, and hypogenetic or heterotopic nerve cells were seen in all forms of malformations. However, the incidence in specific malformations was variable. Multiple giant ganglia were identified in all patients with ...

    Also Ranks for: Intestinal Neuronal |  submucous plexus |  aganglionosis patients |  giant ganglia |  surgical intervention


    Alexander M Holschneider: Influence Statistics

    Sample of concepts for which Alexander M Holschneider is among the top experts in the world.
    Concept World rank
    conjoined xiphoid #1
    secondary sagittal #1
    ladd gross empfohlenen #1
    150 percent prestretching #1
    anal atresia omphalocele #1
    smoothmuscle transposition #1
    paul aegina behandelt #1
    empfohlenen einteilung #1
    manometric histologic #1
    59 wistar rats #1
    recurrent adhesion ileus #1
    children hospital cologne #1
    disintegration transplant #1
    posterior anorectoplasty #1
    ties neonates #1
    twin anesthesia #1
    malformationen paul aegina #1
    formen malformationen #1
    neonates female neonates #1
    rice mittels gross #1
    wurden erstmals suranus #1
    anorectoplasties #1
    fehlbildungen wangensteen #1
    conjoined xiphoid bone #1
    died ileus #1
    animals ileus #1
    atresieformen #1
    percent prestretch #1
    invertogramm ladd gross #1
    weltkrieg douglas stephens #1
    vorschlag kolostomie durchzuführen #1
    graft prestretch #1
    precise preliminary examinations #1
    intestine twin #1
    150 percent transplant #1
    continence improving #1
    stephens erste #1
    erfolgten jedoch erst #1
    fibrosis disintegration #1
    smoothmuscle transplantation #1
    paediatric surgical clinic #1
    instances gracilis #1
    prestretching transplant #1
    rhoads 1948 #1
    small intestine twin #1
    anorectoplasties employed #1
    increasing prestretching #1
    gluteus maximus plasties #1
    transplant prestretching #1
    auszuganorektale fehlbildungen #1

    Key People For Rectal Pouch

    Top KOLs in the world
    Alberto Peña
    anorectal malformations fecal incontinence hirschsprung disease
    Pieter A deVries
    inferior vena cava anorectal anomalies neonatal biliary obstruction
    Alberto Peña
    fecal incontinence secondary operation imperforate child child
    Risto Juhana Rintala
    anorectal malformations bowel function esophageal atresia
    E Durham Smith
    anorectal anomalies closed renal trauma spinal myelomeningocele
    Benno Manfred Ure
    esophageal atresia pediatric surgery laparoscopic cholecystectomy

    Alexander M Holschneider:Expert Impact

    Concepts for whichAlexander M Holschneiderhas direct influence:Rectal pouch,  Colon interposition,  Esophageal atresia,  Chronic constipation,  Intestinal neuronal dysplasia,  Proximal segment,  Anal sphincter,  Anorectal malformations.

    Alexander M Holschneider:KOL impact

    Concepts related to the work of other authors for whichfor which Alexander M Holschneider has influence:Hirschsprung disease,  Esophageal atresia,  Anorectal malformations,  Enteric nervous,  Ganglion cells,  Fecal incontinence,  Intestinal neuronal dysplasia.



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    Immenzaun 6 A, 51429, Bergisch-Gladbach | Kinderkrankenhaus Amsterdamerstrasse, Cologne, Germany | University of Cologne, Germany | The Children’s Hospital of Cologne, Amsterdamerstr. 59, 50735, Cologne, Germany | Immenzaun 6a, 51429, Bergisch Gladba