• Disease
  • Confocal
  • Confocal Microscopy
  • Marco Ardigó

    Prominent publications by Marco Ardigó

    KOL Index score: 11874

    Cutaneous lymphomas are rare in young patients and are mostly represented by mycosis fungoides and its variants and CD30+ lymphoproliferative disorders (lymphomatoid papulosis [LYP] and anaplastic large T-cell lymphoma). We report our observations in a series of 69 patients less than 20 years of age who presented either with primary cutaneous lymphoma (n = 62) or with secondary manifestations of extracutaneous disease (n = 7). Clinicopathologic features permitted classification of the ...

    Also Ranks for: Cutaneous Lymphomas |  20 years |  cell lymphoma |  clinicopathologic features |  mycosis fungoides
    KOL Index score: 11799

    The presence of a granulomatous reaction in lesions of cutaneous lymphomas has been described in the past in several cases. Especially in mycosis fungoides, a "granulomatous" variant of the disease has been well characterized. We studied the clinicopathologic features of cutaneous lymphomas with prominent granulomatous reaction, including both cutaneous T-cell lymphomas and B-cell lymphomas (primary cutaneous lymphoma 22, secondary cutaneous lymphoma one). Biopsies of 23 patients with ...

    Also Ranks for: Cutaneous Lymphoma |  granulomatous reaction |  mycosis fungoides |  histopathologic features |  correct diagnosis
    KOL Index score: 11649

    Vitiligo is a common skin disease characterized by the presence of well circumscribed, depigmented, milky white macules devoid of identifiable melanocytes. Although the detection of circulating anti-melanocytic antibodies and of infiltrating lymphocytes at the margin of lesions supports the view that vitiligo is an autoimmune disorder, its etiology remains unknown. In particular, it is still a matter of debate whether the primary pathogenic role is exerted by humoral or cellular abnormal ...

    Also Ranks for: Cellular Immunity |  major histocompatibility |  specific cytotoxic |  vitiligo patients |  tyrosinase gp100
    KOL Index score: 10996

    BACKGROUND: Mycosis fungoides (MF) is a diagnostic challenge, frequently needing multiple and sequential biopsies to establish the diagnosis.

    OBJECTIVE: Our aim was to evaluate lesions suggestive of MF using in vivo reflectance confocal microscopy (RCM) and to correlate confocal features with histopathologic findings.

    METHODS: A total of 8 lesions from 7 patients either with a history of biopsy-proven MF or with lesions clinically suggestive of MF were imaged with RCM followed by a skin ...

    Also Ranks for: Mycosis Fungoides |  confocal microscopy |  vivo reflectance |  mf histopathology |  histopathologic findings
    KOL Index score: 10631

    BACKGROUND: Several dermoscopic and in vivo reflectance confocal microscopy (RCM) diagnostic criteria of lentigo maligna (LM)/lentigo maligna melanoma (LMM) have been identified. However, no study compared the diagnostic accuracy of these techniques.

    OBJECTIVE: We evaluated the diagnostic accuracy of dermoscopy and RCM for LM/LMM using a holistic assessment of the images.

    METHODS: A total of 223 facial lesions were evaluated by 21 experts. Diagnostic accuracy of the clinical, dermoscopic ...

    Also Ranks for: Confocal Microscopy |  lm lmm |  dermoscopy rcm |  lentigo maligna |  techniques diagnosis
    KOL Index score: 10441

    BACKGROUND: Inflammation represents an early and key event in the development of both the cutaneous psoriasis and psoriatic arthritis. Compelling evidences indicate that the production of TNF-alpha plays a central role in psoriasis by sustaining the inflammatory process in the skin as well as in the joints. Among the multiple effects produced by TNF-alpha on keratinocytes, the induction of matrix metalloproteinase-9 (MMP-9), a collagenase implicated in joint inflammatory arthritis which ...

    Also Ranks for: Psoriatic Arthritis |  decreased levels |  mmp9 sera |  skin lesions |  tnf alpha
    KOL Index score: 9701

    INTRODUCTION: Acne is an inflammatory disease of the pilosebaceous unit, which can be investigated in vivo using reflectance confocal microscopy (RCM) and optical coherence tomography (OCT).

    OBJECTIVES: By means of RCM and OCT to identify morphological characteristics of acne that may be associated with clinical acne severity.

    METHODS: Patients with mild to moderate facial acne (n = 14, Investigators Global Assessment scale, IGA 1-3), and healthy participants (n = 7, IGA 0) were included ...

    Also Ranks for: Optical Coherence |  confocal microscopy |  vivo reflectance |  rcm oct |  acne vulgaris
    KOL Index score: 9451

    BACKGROUND: Discoid lupus erythematosus (DLE) can simulate other inflammatory diseases both clinically and histologically. In vivo reflectance confocal microscopy (RCM) is a noninvasive, reproducible imaging technique already reported to be useful in the evaluation of several inflammatory skin conditions such as contact dermatitis, psoriasis and Darier disease.

    OBJECTIVES: The aims of our study were to define RCM features of DLE and to evaluate its feasibility in biopsy site ...

    Also Ranks for: Lupus Erythematosus |  vivo reflectance |  preliminary evaluation |  microscopy features |  dle rcm
    KOL Index score: 8798

    Tumor necrosis factor-alpha (TNF-alpha) plays a central role in sustaining the inflammatory process in the skin as well as in the joints of patients with psoriasis and psoriatic arthritis. In fact, biological therapies based on monoclonal antibodies against TNF-alpha have been proven to be effective on both the arthropathy and the cutaneous symptoms of the disease. Among the several effects produced by TNF-alpha on keratinocytes there is the induction of expression of MMP-9, a matrix ...

    Also Ranks for: Psoriatic Arthritis |  patients psoriasis |  tnf alpha |  matrix metalloproteinase |  selectin levels
    KOL Index score: 8590

    The identification of neoplastic lymphocytes in early lesions of mycosis fungoides is difficult because of the scarcity of the infiltrate and the presence of reactive T lymphocytes admixed with neoplastic cells. Molecular analysis of the T cell receptor gene rearrangement using the polymerase chain reaction technique demonstrates monoclonality only in a proportion of these cases. The exact location of the malignant clone is unknown, and at present it is not clear whether neoplastic cells ...

    Also Ranks for: Mycosis Fungoides |  molecular analysis |  early lesions |  tcell antigen |  chain reaction
    KOL Index score: 8457

    BACKGROUND AND OBJECTIVE: Malassezia Folliculitis (MaF) is an inflammatory condition of hair follicles caused by Malassezia yeast. Optical coherence tomography (OCT) and reflectance confocal microscopy (RCM) are imaging technologies enabling in vivo visualization of superficial skin layers. This study explores morphology of pustules in MaF imaged by OCT and RCM.

    METHODS: Patients with microscopically verified MaF were included in this case series. Morphology was evaluated qualitatively ...

    Also Ranks for: Malassezia Folliculitis |  confocal microscopy |  optical coherence tomography |  rcm oct |  hair follicles
    KOL Index score: 8109

    BACKGROUND: Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses and fistulas located in apocrine gland-bearing body sites. The negative impact of HS on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL ...

    Also Ranks for: Hidradenitis Suppurativa |  visual tool |  illness surveys |  hurley stage |  hidradisk dlqi
    KOL Index score: 7319

    BACKGROUND: Lichen planopilaris (LPP) and discoid lupus erythematosus (DLE) are the most common causes of lymphocytic primary cicatricial alopecia. The management of scarring alopecia can be difficult. The combination of clinical, dermoscopy and reflectance confocal microscopy (RCM), a noninvasive, high-resolution imaging technique, examinations have already been demonstrated to be useful for choosing the correct biopsy site in patients with inflammatory skin disease and obtaining ...

    Also Ranks for: Scarring Alopecia |  dle rcm |  confocal microscopy |  lupus erythematosus |  lichen planopilaris
    KOL Index score: 7225

    BACKGROUND: Psoriasis is a common skin inflammatory disease that affects 2% of the general population. Plaque psoriasis (PP) is its most common variant. In vivo reflectance confocal microscopy (RCM) is a non-invasive, reproducible imaging technique that has proven to give useful information for morphometric evaluation of several inflammatory skin conditions, such as acute contact dermatitis and discoid lupus.

    OBJECTIVE: This study aimed to define the in vivo RCM features of PP and to ...

    Also Ranks for: Plaque Psoriasis |  normal skin |  confocal microscopy |  vivo reflectance |  rcm evaluation
    KOL Index score: 7207

    BACKGROUND: Actinic keratoses (AKs) are very common lesions on sun damaged skin and, when pigmented, represent a challenge in the differential diagnosis with early melanoma. Non-invasive diagnostic methods, such as dermoscopy and reflectance confocal microscopy (RCM) have been shown to improve the diagnostic accuracy of melanoma and non-melanoma skin cancer, however, only one case report described confocal findings of pigmented AKs up to now.

    OBJECTIVES: The aim of our retrospective ...

    Also Ranks for: Confocal Microscopy |  actinic keratoses |  pigmented aks |  rcm images |  differential diagnosis


    Marco Ardigó: Influence Statistics

    Sample of concepts for which Marco Ardigó is among the top experts in the world.
    Concept World rank
    morphology pustules #1
    oct images pustules #1
    vivo reflectance #1
    ­setting hepatobiliary disease #1
    dermatoses rcm #1
    major rcm features #1
    designs specific indications #1
    confocal tattooing #1
    ctd interface dermatitis #1
    confocal psoriasis #1
    features dle #1
    rcm mpm #1
    measured lesional #1
    grade correspondence #1
    biopsies histopathological diagnosis #1
    oct linear vessels #1
    healthy participants combined #1
    rcm depth #1
    agreement skin dle #1
    rcm demonstrated #1
    pustules malassezia folliculitis #1
    features agvhd #1
    dle features #1
    depigmenting agent complex #1
    tags benign #1
    agreement hp #1
    msot confocal nevus #1
    dermoscopic white #1
    clinically selected lesion #1
    rcm benign nests #1
    rcm inflammation degree #1
    oligopeptide68 phytic acid #1
    consequent progressive increment #1
    spongiotic interface #1
    microscopy inflammatory #1
    hp features agreement #1
    oligopeptide68 #1
    lactic acid octinoxate #1
    study rcm #1
    concrete contribution problems #1
    oct msot #1

    Key People For Confocal Microscopy

    Top KOLs in the world
    Milind M Rajadhyaksha
    confocal microscopy human skin mohs surgery
    Salvador González
    confocal microscopy photodynamic therapy polypodium leucotomos
    Roger Yonchien Tsien
    fluorescent proteins living cells protein kinase
    Watt W Webb
    multiphoton microscopy fluorescence correlation cell surface
    Pellacani Pellacani
    confocal microscopy actinic keratosis basal cell
    Caterina Longo
    confocal microscopy basal cell carcinoma melanocytic lesions

    Marco Ardigó:Expert Impact

    Concepts for whichMarco Ardigóhas direct influence:Confocal microscopy,  Reflectance confocal microscopy,  Vivo reflectance,  Reflectance confocal,  Confocal microscopy rcm,  Inflammatory skin diseases,  Optical coherence,  Skin diseases.

    Marco Ardigó:KOL impact

    Concepts related to the work of other authors for whichfor which Marco Ardigó has influence:Confocal microscopy,  Mycosis fungoides,  Skin cancer,  Cell lymphoma,  Vivo reflectance,  Erosive pustular dermatosis,  Differential diagnosis.



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    San Gallicano Dermatological Institute ‐ IRCCS, Rome, Italy | San Gallicano Dermatological Institute, IRCCS, Rome, Italy | Porphyria and Rare Diseases Unit, San Gallicano Dermatological Institute – IRCCS, Rome, Italy | Clinical Dermatology Department