• Arthritis
  • Arthritis Kols

    Prominent publications by Østergaard Østergaard

    KOL Index score: 24660

    OBJECTIVE: To compare tumor necrosis factor alpha inhibitors directly regarding the rates of treatment response, remission, and the drug survival rate in patients with rheumatoid arthritis (RA), and to identify clinical prognostic factors for response.

    METHODS: The nationwide DANBIO registry collects data on rheumatology patients receiving routine care. For the present study, we included patients from DANBIO who had RA (n = 2,326) in whom the first biologic treatment was initiated (29% ...

    Also Ranks for: Drug Adherence |  adalimumab etanercept |  remission rates |  rheumatoid arthritis |  treatment responses
    KOL Index score: 21805

    OBJECTIVE: To evaluate the effects of golimumab on inflammation/structural damage detected by magnetic resonance imaging (MRI) in patients with rheumatoid arthritis (RA).

    METHODS: Methotrexate (MTX)-naive RA patients (n = 637) were randomized to placebo plus MTX, golimumab 100 mg plus placebo, golimumab 50 mg plus MTX, or golimumab 100 mg plus MTX (subcutaneous golimumab every 4 weeks). Of these, 318 patients participated in an MRI substudy. MRIs (contrast-enhanced; 1.5T) of the wrist ...

    Also Ranks for: Bone Erosion |  methotrexate combination therapy |  magnetic resonance |  golimumab mtx |  arthritis patients
    KOL Index score: 21441

    OBJECTIVES: To investigate the relation between ankylosing spondylitis disease activity score (ASDAS), Bath ankylosing spondylitis disease activity index (BASDAI) and treatment response and biomarkers of inflammation (C-reactive protein (CRP), interleukin-6 (IL-6), YKL-40), angiogenesis (vascular endothelial growth factor (VEGF)), cartilage (C-terminal crosslinking telopeptide of type II collagen (CTX-II), matrix metalloproteinase-3 (MMP-3), total aggrecan, cartilage oligomeric matrix ...

    Also Ranks for: Asdas Basdai |  bone turnover |  treatment responses |  tnfα inhibitors |  axial spondyloarthritis
    KOL Index score: 17442

    OBJECTIVE: To compare ultrasonography (US) with magnetic resonance imaging (MRI), conventional radiography, and clinical examination in the evaluation of bone destruction and signs of inflammation in the metatarsophalangeal (MTP) joints of patients with rheumatoid arthritis (RA).

    METHODS: Two hundred MTP joints of 40 patients with RA and 100 MTP joints of 20 healthy control subjects were assessed with B-mode US, contrast-enhanced MRI, conventional radiography, and clinical examination ...

    Also Ranks for: Clinical Examination |  conventional radiography |  metatarsophalangeal joints |  magnetic resonance imaging |  rheumatoid arthritis
    KOL Index score: 17297

    OBJECTIVE: To investigate changes in magnetic resonance imaging (MRI)-assessed inflammation and structural lesions in the sacroiliac (SI) joints during treatment with adalimumab versus placebo.

    METHODS: In a 48-week double-blind, placebo-controlled trial, 52 patients with spondyloarthritis were randomized to receive subcutaneous injections of either adalimumab 40 mg (n = 25) or placebo (n = 27) every other week for 12 weeks. Patients in the adalimumab group continued to receive and ...

    Also Ranks for: Sacroiliac Joints |  resonance imaging |  patients placebo |  12 weeks |  structural lesions
    KOL Index score: 16879

    BACKGROUND: The objectives of the present study were, with multidetector computed tomography (CT) as the reference method, to determine the performance of magnetic resonance imaging (MRI) and radiography for the detection of bone erosions in rheumatoid arthritis wrist bones, and to test whether measuring volumes of erosions on CT and MRI is reproducible and correlated to semiquantitative assessments (scores) of erosions on CT, MRI and radiography.

    METHODS: Seventeen patients with ...

    Also Ranks for: Bone Erosions |  rheumatoid arthritis |  computed tomography |  resonance imaging |  mri radiography
    KOL Index score: 16743

    OBJECTIVE: To investigate the relationship of circulating biomarkers of inflammation (C-reactive protein [CRP], interleukin-6 [IL-6], and YKL-40), angiogenesis (vascular endothelial growth factor), cartilage turnover (C-terminal crosslinking telopeptide of type II collagen [CTX-II], total aggrecan, matrix metalloproteinase 3 [MMP-3], and cartilage oligomeric matrix protein [COMP]), and bone turnover (CTX-I and osteocalcin) to inflammation on magnetic resonance imaging (MRI) and ...

    Also Ranks for: Radiographic Progression |  bone turnover |  magnetic resonance imaging |  necrosis factor |  monoclonal antibodies
    KOL Index score: 16561

    OBJECTIVE: To evaluate a low field dedicated extremity MRI unit for detection of bone erosions, synovitis, and bone marrow oedema in wrist and metacarpophalangeal (MCP) joints, with a high field MRI unit as the standard reference.

    METHODS: In 37 patients with RA and 28 healthy controls MRI of the wrist and 2nd-5th MCP joints was performed on a low field MRI unit (0.2 T Esaote Artoscan) and a high field MRI unit (1.0 T Siemens Impact) on 2 subsequent days. MRI was performed and evaluated ...

    Also Ranks for: Field Mri |  bone erosions |  sensitivity specificity |  finger joints |  arthritis wrist
    KOL Index score: 16523

    The objective of the study was, with multidetector computed tomography (CT) as the reference method, to determine whether bone erosions in rheumatoid arthritis (RA) metacarpophalangeal (MCP) joints detected with magnetic resonance imaging (MRI) and ultrasonography (US), but not with radiography, represent true erosive changes. We included 17 RA patients with at least one, previously detected, radiographically invisible MCP joint MRI erosion, and four healthy control individuals. They all ...

    Also Ranks for: Bone Erosions |  computed tomography |  mri radiography |  magnetic resonance |  rheumatoid arthritis
    KOL Index score: 15900

    OBJECTIVE: To identify predictors of radiographic progression in a 2-year randomised, double-blind, clinical study (CIMESTRA) of patients with early rheumatoid arthritis (RA).

    METHODS: Patients with early RA (n = 130) were treated with methotrexate, intra-articular betamethasone and ciclosporin/placebo-ciclosporin. Baseline magnetic resonance imaging (MRI) of the wrist (wrist-only group, n = 130) or MRI of wrist and metacarpophalangeal (MCP) joints (wrist+MCP group, n = 89) (OMERACT ...

    Also Ranks for: Mri Bone |  early rheumatoid arthritis |  strongest predictor |  2 years |  radiographic progression
    KOL Index score: 15860

    AIM: To monitor joint inflammation and destruction in rheumatoid arthritis (RA) patients receiving adalimumab/methotrexate combination therapy using MRI and ultrasonography. To assess the predictive value of MRI and ultrasonography for erosive progression on CT and compare MRI/ultrasonography/radiography for erosion detection/monitoring.

    METHODS: Fifty-two erosive biological-naive RA patients were followed with repeated MRI/ultrasonography/radiography (0/6/12 months) and ...

    Also Ranks for: Rheumatoid Arthritis Patients |  mri ultrasonography |  monoclonal antibodies |  erosive progression |  radiography study
    KOL Index score: 15736

    OBJECTIVES: To investigate construct validity and responsiveness of the novel ankylosing spondylitis (AS) disease activity score (ASDAS) in patients with spondyloarthritis (SpA).

    METHODS: In a 46-week prospective longitudinal multicentre study of 60 patients with SpA (80% men, median age 40 years (range 21-62)) treated with tumour necrosis factor alpha (TNFalpha) inhibitors (infliximab, n=41; etanercept, n=13; adalimumab, n=6), the responsiveness of ASDAS, conventional clinical measures ...

    Also Ranks for: Necrosis Factor |  asdas patients |  axial spondyloarthritis |  spondylitis disease |  monoclonal antibodies
    KOL Index score: 15512

    The aim of the present study was to assess ultrasonography (US) for the detection of inflammatory and destructive changes in finger and toe joints, tendons, and entheses in patients with psoriasis-associated arthritis (PsA) by comparison with magnetic resonance imaging (MRI), projection radiography (x-ray), and clinical findings. Fifteen patients with PsA, 5 with rheumatoid arthritis (RA), and 5 healthy control persons were examined by means of US, contrast-enhanced MRI, x-ray, and ...

    Also Ranks for: Psoriatic Arthritis |  magnetic resonance imaging |  patients psa |  bone erosions |  clinical assessment


    Østergaard Østergaard: Influence Statistics

    Sample of concepts for which Østergaard Østergaard is among the top experts in the world.
    Concept World rank
    2nd5th #1
    musculoskeletal imaging rheumatology #1
    intrareader #1
    mri lesions #1
    spine nbf #1
    rese dynamic mri #1
    reference method mri #1
    mcp joints erosions #1
    adcindex #1
    drug survival switchers #1
    finger joint synovitis #1
    mri synovitis rho #1
    starting abatacept #1
    hbl tnfi #1
    arthritis reflect #1
    prescription practice patients #1
    ankylosing spondylitis cil #1
    spondyloarthritis initiating #1
    pros remission rates #1
    marrow oedema #1
    comedication monotherapy #1
    synovial volume #1
    synovitis enthesitis #1
    rheumatologist respondents #1
    omeract task force #1
    mri 1 year #1
    scd206 early patients #1
    patient level agreement #1
    concordant reads #1
    radiography hands #1
    unilateral wrist #1
    crp das28crp #1
    81 respondents #1
    spondyloarthritis – #1
    czp compliance #1
    erosions heal #1
    bone edema mri #1
    convmri #1
    hemris utility #1
    tnfi reference values #1
    sex vnca values #1
    intravenous ofatumumab #1
    adam17 addition #1
    synovitis wrist #1
    drug survivals switchers #1
    drugs crp #1
    additional cya #1
    patients erosive progression #1
    buttock pelvic pain #1
    joint middle #1

    Key People For Rheumatoid Arthritis

    Top KOLs in the world
    Paul Emery
    rheumatoid arthritis ankylosing spondylitis radiographic progression
    Josef Sebastian Smolen
    rheumatoid arthritis systemic lupus erythematosus radiographic progression
    James F Fries
    rheumatoid arthritis physical function systemic lupus erythematosus
    John Turner Sharp
    rheumatoid arthritis radiographic progression joint space width
    Frederick J Wolfe
    rheumatoid arthritis work disability rheumatic diseases
    Matthew H Liang
    rheumatoid arthritis systemic lupus erythematosus lyme disease

    Østergaard Østergaard:Expert Impact

    Concepts for whichØstergaard Østergaardhas direct influence:Rheumatoid arthritis,  Magnetic resonance imaging,  Psoriatic arthritis,  Magnetic resonance,  Axial spondyloarthritis,  Resonance imaging,  Radiographic progression,  Patients rheumatoid arthritis.

    Østergaard Østergaard:KOL impact

    Concepts related to the work of other authors for whichfor which Østergaard Østergaard has influence:Rheumatoid arthritis,  Ankylosing spondylitis,  Magnetic resonance imaging,  Radiographic progression,  Rheumatic diseases,  Clinical remission,  Sacroiliac joints.



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    Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup, Denmark. | Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup and Department of Clinical Medic