• Arthritis
  • Arthritis Kols

    Prominent publications by Edward Keystone

    KOL Index score: 12528

    OBJECTIVE: Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis (RA). The phase III, 24-month, placebo-controlled Oral Rheumatoid Arthritis (ORAL) Scan trial was undertaken to evaluate the efficacy, including inhibition of structural progression, and safety of tofacitinib in patients with active RA and an inadequate response to methotrexate (MTX). Month 24 data from the completed study are reported here.

    METHODS: Patients were randomized 4:4:1:1 to receive ...

    Also Ranks for: Tofacitinib Patients |  phase iii |  safety outcomes |  rheumatoid drug therapy |  agents arthritis
    KOL Index score: 6310

    OBJECTIVE: To evaluate the reliability of concurrent flare identification using 3 methods (patient, rheumatologist and Disease Activity Score (DAS)28 criteria), and construct validity of candidate items representing the Outcome Measures in Rheumatology Clinical Trials (OMERACT) RA Flare Core Domain Set.

    METHODS: Candidate flare questions and legacy measures were administered at consecutive visits to Canadian Early Arthritis Cohort (CATCH) patients between November 2011 and November 2014. ...

    Also Ranks for: Rheumatoid Arthritis |  patients flare |  outcome measures |  construct validity |  disease activity score


    Edward Keystone: Influence Statistics

    Sample of concepts for which Edward Keystone is among the top experts in the world.
    Concept World rank
    defined lda #32
    cdai defined #42
    initiating tofacitinib #52
    flaring patients #96
    flare status #97
    flares rheumatoid arthritis #97

    Key People For Rheumatoid Arthritis

    Top KOLs in the world
    Paul Emery
    rheumatoid arthritis ankylosing spondylitis radiographic progression
    Josef Sebastian Smolen
    rheumatoid arthritis systemic lupus erythematosus radiographic progression
    James F Fries
    rheumatoid arthritis physical function systemic lupus erythematosus
    John Turner Sharp
    rheumatoid arthritis radiographic progression joint space width
    Frederick J Wolfe
    rheumatoid arthritis work disability rheumatic diseases
    Matthew H Liang
    rheumatoid arthritis systemic lupus erythematosus lyme disease

    Edward Keystone:Expert Impact

    Concepts for whichEdward Keystonehas direct influence:Rheumatoid arthritis,  Inadequate response,  Patients tofacitinib,  Rheumatology patients,  Tofacitinib patients,  Patients rheumatoid arthritis,  Safety tofacitinib,  Treatment rheumatoid arthritis.

    Edward Keystone:KOL impact

    Concepts related to the work of other authors for whichfor which Edward Keystone has influence:Rheumatoid arthritis,  Smartphone app,  Patients tofacitinib,  Small molecule inhibitors,  Radiographic progression,  Hoc analysis,  Inadequate response.



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    The Rebecca MacDonald Centre for Arthritis, Mount Sinai Hospital, Toronto, ON, Canada. | Mount Sinai Hospital Toronto, Ontario Canada