Joel A. Block

Joel A. Block

From The *cook County Health & Hospital Systems; †midwest Orthopedics Rush University Medical Center; ‡division Of Rheumatology, Rush University Medical Center; ...

Direct Impact

Concepts for which Joel A Block has direct influence:

rheumatoid arthritis
systemic lupus erythematosus
chondrosarcoma cells
muscle strength
physical function
radiographic joint space width
etanercept therapy

External impact

Concepts related to the work of other authors for which Joel A Block has influence:

systemic lupus erythematosus
rheumatoid arthritis
anca-associated vasculitides
spanish lupuspro
knee pain
remission-maintenance regimens
thrombotic thrombocytopenic purpura

Prominent publications by Joel A. Block

Raynaud's Phenomenon

KOL-Index: 58 Raynaud's phenomenon is characterised by episodic vasospasm of the fingers and toes typically precipitated by exposure to cold. Mild Raynaud's is common and is not usually a harbinger of clinically important disability; its onset, however, can be startling and uncomfortable for patients, and the well recognised association in some cases with systemic rheumatic conditions often precipitates ...
Known for
Calcitonin Gene-Related Peptides | Endothelium-Independent | Potential Therapeutics | Systemic Rheumatic Conditions
KOL-Index: 40 OBJECTIVE: The present study was undertaken to conduct a phase IV, open-label, prospective study to characterize the long-term safety of rituximab in a 4-year observational registry of adult patients with granulomatosis with polyangiitis (GPA) or microscopic polyangiitis (MPA) within the US. METHODS: Patients initiating treatment with rituximab were evaluated every 6 months for up to 4 ...
Known for
Estimated Rates | Rituximab Gpa | Polyangiitis Mpa | Shorter Durations
KOL-Index: 31 The study compares patient–physician discordance in global assessment in patients with osteoarthritis (OA) versus patients with rheumatoid arthritis (RA) seen in routine care. This is a cross-sectional study conducted at an academic rheumatology center at which all patients are asked to complete a Multi-Dimensional Health Assessment Questionnaire (MDHAQ), which includes a patient global ...
Known for
Patgl-Docgl ≥ | Explanatory Discordance | Logistic Regressions | Academic Rheumatology Center
KOL-Index: 31 OBJECTIVES: To describe the association between thrombotic thrombocytopenic purpura (TTP) and systemic sclerosis (SSc) and the methods to distinguish TTP from scleroderma renal crisis (SRC). METHODS: A case of TTP that developed in a patient with preexisting SSc is described. Medline/PubMed was searched for literature pertaining to an association between TTP and SSc, with special attention ...
Known for
Distinction Src | Purpura Systemic | Ssc Literature | Diagnosis Ttp
KOL-Index: 28 PURPOSE OF REVIEW: Anti-nerve growth factor (NGF) antibodies hold tremendous potential for the management of osteoarthritis pain, but clinical trials have revealed serious adverse effects that are incompletely understood. This review discusses clinical trial results along with preclinical studies that have assessed NGF blockade in experimental osteoarthritis, in order to provide insight for ...
Known for
Trials Revealed | Trial Preclinical | Management Osteoarthritis | Anti Ngf
KOL-Index: 27 Literature-related discovery (LRD) is the linking of two or more literature concepts that have heretofore not been linked (i.e., disjoint), in order to produce novel, interesting, plausible, and intelligible knowledge (i.e., potential discovery). The open discovery systems (ODS) component of LRD starts with a problem to be solved, and generates solutions to that problem through potential ...
Known for
Ods Lrd Approach | Rps | ∼130 Potential Discoveries | Potential Rp Treatments
KOL-Index: 26 Knee osteoarthritis (OA) is a common and morbid condition. No disease-modifying therapies exist; hence the goals of current treatment are to palliate pain and to retain function. OA is significantly influenced by the placebo effect. Nonpharmacologic interventions are essential and have been shown to improve outcomes. Canes, unloading braces, and therapeutic heating/cooling may be valuable. ...
KOL-Index: 26 OBJECTIVES: Tenascin-C (TNC) is an oligomeric glycoprotein of the extracellular matrix that is prominently expressed in malignant tumors. The purpose of this study was: (1) to determine the in vitro TNC splicing pattern in cultured human chondrocytes and chondrosarcoma cells, (2) to determine the in vivo TNC splicing pattern in clinical chondrosarcoma specimens, and (3) to perform survival ...
Known for
Determine Tnc | Cultured Chondrocytes | Survival Vitro | Oligomeric Glycoprotein
KOL-Index: 25 OBJECTIVES: The objective of this paper is to perform the cross-cultural validation of the French version of the LupusPRO, a disease-targeted patient-reported outcome measure, among systemic lupus erythematosus (SLE) patients in Canada. METHODS: The French version of the LupusPRO and the MOS SF-36 were administered; demographic, clinical and serological characteristics were obtained. Disease ...
Known for
Convergent Discriminant Validity | Consistency Reliability | Cross-Cultural Validation | French Canadian

From the *Cook County Health & Hospital Systems; †Midwest Orthopedics Rush University Medical Center; ‡Division of Rheumatology, Rush University Medical Center; §Division of, Rush University, Chicago, IL.

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