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    • Rikard Holmdahl
    • Rikard Holmdahl

      Rikard Holmdahl

      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China | Medical ...

       

       

      Kol Lebenslauf für Rikard Holmdahl

      Year
      2022

      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

      Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku, Finland

      2021

      The Second Affiliated Hospital of Xi’an Jiaotong University (Xibei Hospital), Xi’an, China

      Department Medical Biochemistry and Biophysics, Division Medical Inflammation Research, Karolinska Institute, 171 77 Stockholm, Sweden;, (M.A.);, (X.C.);, (B.X.);, (G.F.L.);, (M.Y.B.);, (Y.H.);, (L.B.)

      Division of Medical Inflammation Research, Dept. of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden

      2020

      Dept. of Medical Inflammation Research, Section of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm

      Section for Medical Inflammation Research, BMCI11, Lund University, Lund, Sweden

      National & Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital, Xi'an Jiaotong University, 710004 Xi’an, China

      Karolinska Institutet

      2019

      Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Solnavägen 9, 171 65, Solna, Sweden

      Center for Medical Inflammation Research, Southern Medical University, Guangzhou, China

      R. Holmdahl and C.I. Svensson contributed equally to this paper.

      2018

      School of Pharmaceutical Science, Southern Medical University, Guangzhou, China

      Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address:

      Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

      Medicity Research Laboratory, University of Turku, Turku, Finland

      2017

      Karolinska Institutet Division of Medical Inflammation Research Stockholm Sweden

      Center for Medical Immunopharmacology Research, Southern Medical University, 510515 Guangzhou, China.

      Medicity Research Laboratory, University of Turku, Turku, Finland, .

       

       

      Rikard Holmdahl: Einflussstatistik

      Beispiel von Konzepten, für die Rikard Holmdahl gehört zu den Top -Experten der Welt.
      Concept World rank
      cii dendritic cells #1
      dth nzb mice #1
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      function nox2 #1
      pia disease #1
      collagen reactivity cxi #1
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      caia lps #1
      comp arthritis models #1
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      caia monoclonal #1
      single monoclonal #1
      tnfα tlr3 expression #1
      insulitis strains #1
      reactivity cb268 #1
      ncf1 polymorphism #1
      oxazolone inflammatory response #1
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      arthritis qtl pia7 #1
      collagen antibodies #1
      keratinocytes dth reaction #1
      role ncf1 #1
      lps caia #1
      beta 10b beta #1
      interacting subloci #1
      realtime pcr flss #1
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      lack arthritis #1
      rheumatoid arthritis immunization #1
      chromosome congenic strains #1
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      severity cia #1
      macrophages mannans #1
      mice ros #1
      mem lglutamine #1
      ncf1 mice wt #1
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      339 polymorphism #1
      induction cii #1
      promoter regions antigens #1
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      polymorphism autoimmune diseases #1
      double deficiency qa2 #1
      h2p h2q #1
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      collagen induced #1
      glycosylated cii259 #1
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      effects fab2 #1
      strains b10q #1
      cell specificity cii #1
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      pristane macrophages #1
      expression liver receptor #1
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      developed arthritis #1
      cia reduction #1
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      antigenic adjuvant #1
      mice salt concentrations #1
      preformed cartilage #1
      autoimmune accelerating #1
      6 cii #1
      cia experimental arthritis #1
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      polymorphic fragment #1
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      collagen citrullination #1
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      male mice arthritis #1
      anticcp2negative patients #1
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      b10q h2q #1
      protein expression genes #1
      olive oil arthritis #1
      representative swedish #1
      frequency chronic arthritis #1
      ethylene isostere #1
      inflammation caia #1
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      ciispecific cells day #1
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      homologous type collagen #1
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      cii heterologous cii #1
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      ccp2 negative #1
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      bal cells work #1
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      cb268 #1
      ciic1 ciif4 #1
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      cia swr mouse #1
      frequency igaproducing cells #1
      monoclonal cartilage cattle #1
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      256 270 #1
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      functional ncf1 macrophages #1
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      nox2 complex ncf4 #1
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      cii259 #1
      established sialadenitis #1
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      immunologic animals arthritis #1
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      kgf chondrocytes #1
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      mice functional ncf1 #1
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      peripheral cells alphachains #1
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      cia h2p #1
      rats pristaneinduced arthritis #1
      cartilage‐specific antibodiesis #1
      cia tsc transgenic #1
      tolerance collagen #1
      caia mab #1
      h2w3 #1
      cii experimental autoantigens #1
      arthritis tlr3 #1
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      ccp positive patients #1
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      b10qnfr #1
      antibodies pc4 #1
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      multiple sclerosis rabeximod #1
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      heterologous cii #1
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      cii259273 peptide #1
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      models rheumatoid #1
      phenotypes ncf1m1j mice #1
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      cii triple #1
      downregulating oestradiol #1
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      stages arthritis #1
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      placental mhc class #1
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      pia model rats #1
      pristaneprimed cells #1
      cia antigens haplotypes #1
      phagocytic nox2 complex #1
      clonal expansion arthritis #1
      c3bireceptors #1
      tumor models ncf1 #1
      authors hgpi325339 peptide #1
      aq molecule #1
      ftirm ciic1 #1
      psich2nh2 #1
      ciif4 cartilage explants #1
      findings new therapy #1
      dth nzb #1
      pristaneinduced arthritis #1
      rats cxi #1
      surface redox levels #1
      susceptible strain cross #1
      animal epitopes #1
      ncf1 #1
      p47phoxv232 #1
      streptococcal endo #1
      dth response mrl #1
      arthritis ides #1
      type disease #1
      mcaia #1
      re04001activatedfpr1 #1
      region eae2 #1
      chick cii cii #1
      mice anticd4 treatment #1
      susceptible collagen #1
      rheumatoid arthritis eae #1
      cb268 cii #1
      hfdmets #1
      ppt medium #1
      oxidative burst inducers #1
      inbred dba prolactin #1
      genetic regions #1
      rt1u lew1w #1
      mice b10q #1
      cia locus #1
      expressions cyp7a1 #1
      mhc genetic region #1
      oils induce #1
      riiis alleles eae2 #1
      cxi cii #1
      4 histone deacetylases #1
      eae b10riii mice #1
      pia3 pia4 #1
      citrulline collagen #1
      rat cb10 cb11 #1
      rt1bβ #1
      collagen ii‐induced #1
      denatured cii #1
      vivo treatment #1
      compia #1
      skg mutation #1
      mice ncf4 #1
      transgenic nadph #1
      cii cartilage explants #1
      avridine arthritis #1
      collagen‐induced arthritis #1
      rat cii cii #1
      chromosomes eae loci #1
      mcaia ncf1 #1
      arthritis pnipaam #1
      pparγ cbrh7919 cells #1
      mice th1 cytokines #1
      immune cartilage #1
      driven psoriatic arthritis #1
      thymectomy transgenes #1
      arthritis estrogen treatment #1
      development inflammatory attack #1
      damage type collagen #1
      loci sialadenitis #1
      nod nss1 #1
      impact topoisomerase antagonist #1
      cells rat cii #1
      fls ppt medium #1
      gergaagiagpk #1
      terpenes toll #1
      chronic arthritis mice #1
      mmc transgene #1
      dba 1 #1
      ciid3 #1
      vivo monoclonal #1
      pia rats arthritis #1
      peritonitis sod3 #1
      arthritogenic mabs #1
      obs electrophoresis #1
      wo2012127214 #1
      genetic crossbreeding #1
      cii development #1
      cryogel column antibodies #1
      rats synthetic peptide #1
      cartilage stability cartilage #1
      impact etoposide #1
      role eosinophilia #1
      pinealectomy exposure #1
      ciispecific #1
      heterologous cii cells #1
      rheumatoid arthritis complexity #1
      cii specific #1
      activation cii #1
      cia rheumatoid arthritis #1
      ym1 pneumonitis #1
      relapsing arthritis #1
      epitopes cii #1
      chromosome caia #1
      c57bl strains loci #1
      cia melatonin #1
      b10riii #1
      cii256270 #1
      cii cb fragments #1
      arthritis pepsin #1
      disease genotype immunoglobulin #1
      collagen type‐ii epitope #1
      phemagelatin #1
      ability gut protection #1
      cii peptides #1
      sensitive wkymvm #1
      ncf1da #1
      congenic mice vdr #1
      adjuvant oils #1
      severe polyarthritis #1
      cii pia #1
      emulsions induction #1
      innate immunity mip #1
      cia cells #1
      established pia disease #1
      arthritis rat #1
      ncf1 gene #1
      arthritis adjuvants #1
      disease lew #1
      comp experimental autoantibodies #1
      ncf1deficient mice #1
      mir144 tlr2 expression #1
      genes animal models #1
      synovial membranes joints #1
      function p47phox #1
      chromosome arthritis severity #1
      cd4 treatment #1
      cia caia #1
      phagocyte oxidative burst #1
      arthritis rat strains #1
      rats severity #1
      qa2 natural mutations #1
      collagen iiinduced arthritis #1
      melatonin cia #1
      arthritis b6n mice #1
      concentrations mouse cii #1
      riiis segment chromosome #1
      c3hq mice #1
      cia b10q #1
      drb10401 col2259 #1
      illness terpenes #1
      disease dba 1jpfp #1
      immunodominant cii #1
      rat pristaneinduced arthritis #1
      cia11 #1
      autoimmune diseases identification #1
      nox2 complex #1
      tolerance arthritis susceptibility #1
      glycosylated cii #1
      rats pia #1
      new therapy arthritis #1
      models rheumatoid arthritis #1
      arthritis development severity #1
      eae3 chromosome #1
      arthritogenic mabs cii #1
      arthritis chronic #1
      cia compdeficient mice #1
      arthritis caia #1
      experimental arthritis autoimmune #1
      immunization type #1
      hladrβ10402 #1
      ncf1 nos2 #1
      bb2bb3 #1
      cii 6 #1
      anticii abs #1
      position cii256270 #1
      comp cii #1
      muscle nox2 #1
      physiological doses development #1
      ncf1 copy variation #1
      tcell experimental cartilage #1
      ifnbeta arthritis #1
      cii antibodies #1
      caia kgf #1
      synovium pia rats #1
      liver contributes hfdmets #1
      estrogeninduced suppression #1
      type epitopes #1
      l012 vivo imaging #1
      ros immunohistochemistry implants #1
      human immunopeptidome lung #1
      ciic1 mabs #1
      mannan immune #1
      celldependent disease #1
      plasminogendeficient mice arthritis #1
      fcγr3 #1
      ncf1m1j mice function #1
      hydrolyzed igg #1
      h2q mice #1
      fecq3 locus #1
      oestrogen treated #1
      ros nox2 complex #1
      targeted mutation ncf4 #1
      act389949 fpr #1
      rats rt1f mhc #1
      response splenocytes #1
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      arthritis susceptibility rats #1
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      ncf4 mip #1
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      cells dba mouse #1
      cells arthritis progression #1
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      eae2 locus #1
      bcell activities #1
      nod nss1 loci #1
      emerging glyco‐based strategies #1
      genome b10riii #1
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      ftirm mice #1
      ncf4 mice #1
      rat cii response #1
      regulates severity #1
      genes ncf1 #1
      hg6pi325 #1
      collagen 256 #1
      eae39 locus cia #1
      ncf1 allele #1
      alphachains cell surface #1
      native cii #1
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      differential susceptibility cia #1
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      prevents arthritis #1
      controlling onset #1
      chronic development #1
      therapeutic c4bp #1
      act389949 agonist #1
      presence mhv #1
      congenic arthritis rats #1
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      ncf1 ros #1
      igg1 igg2b isotypes #1
      ul1 ciif4 mab #1
      p47phox mutant #1
      cxi pia #1
      cartilage‐specific #1
      cd43expressing cells #1
      joint inflammatory phase #1
      cells ncf1 #1
      cii acpa #1
      h‐2q #1
      kupffer cells mir144 #1
      dba 1 background #1
      hyaluronanreceptor cd44 #1
      adaptive immunity fcγrs #1
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      severe arthritis immunization #1
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      identification genetic regions #1
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      development chronic arthritis #1
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      collagen cxi #1
      induction postpartum flare #1
      urokinase enzyme #1
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      daxlewf1 #1
      pc4 pc8 #1
      psoriasis single locus #1
      collagen arthritis progesterone #1
      experimental carcinogens #1
      immunization autologous peptide #1
      nodq nod nodp #1
      arthritis intraperitoneal injection #1
      function targeted deletion #1
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      cii peptide molecules #1
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      molecule aq #1
      synthetic peptides cii #1
      restricted role fcγr #1
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      haplotype ltab #1
      b10riii riiis #1
      pepsin arthritis #1
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      ncf1 spread #1
      deficient ncf1 #1
      mice cii immunization #1
      b10dr4ncf1 mice cii #1
      active arthritis complex #1
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      17βestradiolregulation #1
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      oxa backcrosses #1
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      pristane induced #1
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      arthritis onset severity #1
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      increased salt exposure #1
      early onset development #1
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      suppression collagen arthritis #1
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      glycosylation cell recognition #1
      h2p cia #1
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      phase arthritis #1
      ​methods #1
      pc117 #1
      dimethyl6n #1
      mice l012 #1
      citrullinated collagen arthritis #1
      autoantibody responses cii #1
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      tolerance arthritis protection #1
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      histology vaccination #1
      cia eae39 #1
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      ym1 alternative activation #1
      ncf1m1j mice ncf1 #1
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      cii antigen presentation #1
      major cii #1
      hiit nox2 activity #1
      nox2complex #1
      hyaluronanreceptor #1
      glycoprotein alpha1microglobulin #1
      cartilage cii #1
      rats chronic disease #1
      polychondritis autoimmune disease #1
      dth mice trait #1
      p47phox ncf1 #1
      myelomonocytic arthritis interleukin2 #1
      cia caia model #1
      qtl positional cloning #1
      collagen reactive #1
      pia3 chromosome #1
      pristaneinduced arthritis rats #1
      congenic fragment #1
      cia rheumatoid autoantibodies #1
      rabeximod arthritis #1
      collagen epitopes #1
      mrl mice estrogen #1
      dba 1j #1
      beta 812 #1
      response cii #1
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      pia cia13 pia7 #1
      cii pepsin #1
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      ciispecific cell responses #1
      cells caia #1
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      position 264 #1
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      maintained pregnancy levels #1
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      macrophages cii #1
      disease cd8 deficiency #1
      cxi rats #1
      minimal glycopeptide core #1
      cii arthritis #1
      cia22 #1
      healthy nzw #1
      severity arthritis #1
      dominant traits #1
      arthritis naive mice #1
      citrullinated variants #1
      positional identification #1
      collagen cii #1
      endos hydrolyzed igg #1
      etoposide topoisomerase antagonist #1
      cii cells #1
      sialadenitis incidence #1
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      cix disease #1
      cxi comp #1
      csfspecific #1
      cells autologous cii #1
      targeted deletion ncf1 #1
      functional selective fpr1 #1
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      ifa rats #1
      cii chronic #1
      b10qc5δ #1
      arthritis qtl chip #1
      oestradiol suppression #1
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      beta haplotype #1
      oia induction #1
      selfcii #1
      striking phenotypic similarities #1
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      immunisation cells #1
      models collagen #1
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      kgf cia #1
      tcell hybridomas cells #1
      collagen arthritis iii #1
      citrullinated type #1
      strains nodq #1
      clec4b #1
      h‐2q mice #1
      pia2–8 #1
      rs201802880 #1
      mip cia #1
      mice cryogels #1
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      tcell congenic arthritis #1
      lnchc cholesterol metabolism #1
      macrophage ros #1
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      role nox2derived ros #1
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      flss polyi #1
      rp autoimmune disease #1
      autoimmunogenic hydrocarbon oils #1
      pathway arthritis #1
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      presence sex hormones #1
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      rat placenta uterus #1
      chondrocytes kgf #1
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      signaling characterization #1
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      kgf treatment onset #1
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      genetic variants ncf1 #1
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      mice salt intake #1
      cii polymer #1
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      periodontitis rats pia #1
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      arthritis genetics #1
      disease glycoproteins #1
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      ros adaptive immunity #1
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      developed severe #1
      ncf1 mutant #1
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      cd200 btla #1
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      b10qncf1 mice #2
      autoimmune membrane proteins #2
      18ffluoromannan #2
      antibody cartilage #2
      cd19 cells egfp #2
      anticii antibody #2
      cells arthritis #2
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      da1u rats #2
      cep1 fibß62 #2
      ala261 #2
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      granulomas cgd mice #2
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      raloxifene estradiol treatment #2
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      incidence nephritis #2
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      conditions igke promoter #2
      pristane injection #2
      ptpn22 ncf1 #2
      igsecretors #2
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      fibβ36 #2
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      ros peroxide #2
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      alterations neuroendocrine profile #2
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      mbp peptides immunization #2
      tracheolaryngeal cartilage rp #2
      influence chromosome #2
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      rats disease onset #2
      ncf1 mutants #2
      genotypes ovx #2
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      linomide homologous cia #2
      cxi l10d9 antibody #2
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      adjuvant rats #2
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      collagen arthritis cii #2
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      elastaseinduced emphysema nox2 #2
      ifngamma spinal cord #2
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      cia monkeys #2
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      rats polymorphism #2
      collagen citrullination adhesion #2
      collagen ii‐induced arthritis #2
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      collagen antibody #2
      18fbicyclo610nonyne #2
      rats lymphocytes #2
      ccp2 diagnostic accuracy #2
      salt intake vivo #2
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      mph induction #2
      arthritogenic mab cii #2
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      transgenic oxidases zymosan #2
      mice genistein treatment #2
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      binding cartilage #2
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      neutrophil functions modulation #2
      antibody‐mediated arthritis #2
      das28 values p001 #2
      ptpn22 protein disulfide #2
      transgenic osteoporosis oestradiol #2
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      positive anticcp2 test #2
      igkeegfp lentivirus expression #2
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      pia rats #2
      h2q mice mice #2
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      fibα563 #2
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      eae dxea strain #2
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      mbp 87110 peptide #2
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      arthritis female #2
      antileukoproteinase alp #2
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      higher levels anas #2
      analyses comp #2
      rats da1u #2
      cii depletion #2
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      dxea strain tgfbeta #2
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      disease 111 #2
      adjuvant oils arthritis #2
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      animal haplotypes #2
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      disease humanized mice #2
      flow cytometry ovx #2
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      utility comp #2
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      rats utility #2
      ptpn22 c129s #2
      chitosanagarosegelatin #2
      disease promoting #2
      caia effector phase #2
      mannan induced #2
      l10d9 antibody cartilage #2
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      citcii311 #2
      cpg2088 #2
      fibα580 #2
      ros source #2
      fibß62 #2
      mabs comp #2
      induction cia #2
      arthritis ethanol #2
      selective fpr1 #2
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      lack functional nox2 #2
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      species susceptible haplotypes #2
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      cartilage respiratory #2
      synovial immune reactions #2
      hiit skeletal muscle #2
      mbp89 #2
      matrilin cartilage proteins #2
      anticd4 treatment #2
      induction p47phoxmutated mph #2
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      control subjects samples #2
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      epitope glycosylation #2
      arthritis fb #2
      igg glycosylation arthritis #2
      fpr1 neutrophils #2
      cia mechanisms #2
      fil307 #2
      single nucleotide rats #2
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      caia oestradiol #2
      12 590 #2
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      c2ta mhcii expression #2
      etoposide serum concentrations #2
      oxidation c129s #2
      terpenes animals #2
      psychosocial stress hpaaxis #2
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      cii ciic1 #2
      symptoms anti ccp2 #2
      mhcii experimental arthritis #2
      clever1 tumor #2
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      injection w3 13 #2
      shared epitope cxi #2
      myelin ppd #2
      034positive #2
      c129s mutant disulfide #2
      citcii #2
      igke #2
      cii311 #2
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      glycopeptides histocompatibility #2
      mitochondria polymorphism #2
      chronic arthritis treatment #2
      mab cii #2
      putative vulnerability locus #2
      agonist study #2
      c1epitope #2
      fpr1 signaling #2
      receptor‐specific manner #2
      redox regulation ptpn22 #2
      antileukoproteinase modulation #2
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      anticcp2negative presence #2
      ere activation treatment #2
      ciif4 #2
      pnipaam vpba #2
      cgd mice kynurenine #2
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      nadph oxidase elevations #2
      h2q #2
      b10qncf1 mice cia #2
      incidence insulitis #2
      lew mol #2
      disease development presence #2
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      murine locus eae2 #2
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      congenic mice autoimmune #2
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      igke promoter #2
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      cartilage proteins sera #2
      paws mice #2
      mice collagen #2
      dxea strain #2
      cartilage‐specific autoimmunity #2
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      immunization mouse collagen #2
      antibodies cartilage #2
      disease cyclosporin treatment #2
      rno12 #2
      apc naïve cells #2
      prophylactic treatment linomide #2
      human lung nox2 #2
      comp cartilage #2
      l10d9 antibody cxi #2
      re04 #2
      ncf1gene #2
      da1u #2
      arthritis progression #2
      tolerance cii #2
      igkeegfp lentivirus #2
      antipan #2
      peptides chronic eae #2
      hiit skeletal #2
      oestradiol cia #2
      tregs mph #2
      eae protein rna #2
      epitope‐specific recognition #2
      biologicals 24 months #2
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      collagen arthritis immunization #2
      mhc iii #2
      111 vivo treatment #2
      cia disease #2
      caia #2
      lymphocytelike #2
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      eae cia #2
      cd8 cells incidence #2
      chromosome rats #2
      ciic1 #2
      rtlu #3
      allogeneic pregnancy #3
      arthritis effects #3
      hfdmets rats #3
      mice development #3
      disease w3 13 #3
      differences citrullinated peptides #3
      mice copolymers #3
      targeting toll #3
      fibα573 #3
      ifnbetadeficient mice #3
      antibodies vim60 #3
      cryogel bioreactor #3
      points acs #3
      height disease #3
      81b #3
      cystatin cdeficient mice #3
      animal glycosylation humans #3
      h2qbearing #3
      acpas twins #3
      rats disease #3
      spe dce #3
      dce spe #3
      acpapositive twins #3
      nerve terminallike profiles #3
      wildtype mice granulomas #3
      arthritis autoimmunity #3
      cvrelated death #3
      advanced intercross eae5 #3
      complex genetic control #3
      95 cvrelated death #3
      loci antibodies #3
      ifngamma neurons #3
      development acpas #3
      monoclonal cartilage sections #3
      hdac1 pathogenesis #3
      cep1 filaggrin #3
      rheumatoid cloning #3
      arthritis susceptible #3
      cii reactive #3
      genetic influence susceptibility #3
      vivo control mice #3
      arthritis resistance #3
      nox2 cgd #3
      experimental cell #3
      eae17 #3
      acpa combination #3
      cia strains #3
      mnc salivary glands #3
      vim60 #3
      disease genotype immunity #3
      ncf4 rs729749 #3
      glycosylated type #3
      crossreactive idiotope #3
      subspecificities associations #3
      induced immunospecific tolerance #3
      models arthritis #3
      cd8 cells ean #3
      ncf1 cldn4 #3
      genotype knowledge #3
      disease immunization #3
      cvrelated death adjustment #3
      oxidase 2 #3
      endogenous ifnbeta #3
      restricted role #3
      common mouse model #3
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      rt1a tap2 #3
      eae1 #3
      arthritis susceptibility #3
      citrullinated peptides multiplex #3
      lupus nets #3
      genes disease development #3
      allopregnancy #3
      arthritis review #3
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      cii species #3
      keratinocytes langerhans cells #3
      cyp7a1 abca1 #3
      cells naïve mice #3
      ifngammali #3
      onset combination #3
      ean mca #3
      type collagen vivo #3
      antigen presentation mhcii #3
      type c2ta #3
      dancf1e3 #3
      reactive idiotope #3
      neutrophils eae #3
      eae17 chromosome #3
      cartilage proteins #3
      fibβ74 #3
      rheumatoid autoimmune #3
      dnfb ears #3
      early phase disease #3
      disease height #3
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      species lymphocytes #3
      dxea #3
      sialadenitis #3
      development arthritis #3
      fibα573 fibβ74 #3
      isotypes acpas #3
      citrulline inflammation #3
      eae31 #3
      anti‐type #3
      twins acpas #3
      development collagen arthritis #3
      fibβ62 81b #3
      h2p mice #3
      citc1iii #3
      clever1 macrophages #3
      citc1iii fibα573 #3
      autoimmunity pia #3
      treatment arthritis #3
      bcg ros #3
      mice constant light #3
      minimal adjuvant requirement #3
      antigens keratinocytes #3
      rheumatoid crosses #3
      fibα591 #3
      rs729749 #3
      arthritis levels #3
      mice rheumatoid #3
      h2aalpha #3
      female preponderance #3
      rats rheumatoid arthritis #3
      cytotoxic t‐lymphocyte #3
      oxidases reactive #3
      cdk6 padi4 #3
      incidence antinuclear antibodies #3
      apc cia #3
      lew ztm #3
      autoimmunity cartilage #3
      acpas fine specificities #3
      arthritogenicity #3
      twins acpapositive #3
      processing cii #3
      ros deficiency #3
      arthritogenic mab #3
      experimental arthritis #3
      db1 treatment #3
      cd4∶cd8 lineage #3
      acpa subspecificities #3
      cia hdac1 #3
      antibodies induce #3
      pristane‐induced arthritis #3
      carriers hladrb104 #3
      arthritis model #3
      cd4∶cd8 lineage commitment #3
      hdac1 rheumatoid arthritis #3
      origin suggestive linkage #3
      acpas plasma #3
      citcii355 #3
      c57bl mice illness #3
      eae5 pia4 #3
      acpa specificities presence #3
      ctla4 deletion #3
      citrullinated peptides time #3
      lew1f #3
      swedish patients antibodies #3
      mice environments #3
      citrullinated cyclic #3
      stroke cvrelated death #3
      fibβ74 onset #3
      arthritis animal model #3
      immuniozation #3
      dthreaction #3
      fibα573 fibα591 #3
      mmc mice #3
      acpa multiplex #3
      rs729749 ncf4 #3
      igl genes #3
      aureus arthritis mice #3
      antibodies citrullinated #3
      chronic collagen #3
      disease anti lymphocyte #3
      antigens collagen #3
      disease development contribution #3
      inflamed synovial tissues #3
      ifngammali neurons #3
      transgenic osteoporosis #3
      eae16 #3
      osteoclasts release #3
      rats mog #3
      combination acpa #3
      db1 treatment day #3
      recombination rt1a #3
      nox2 pathogenesis #3
      pia6 #3
      macroporous gel particles #3
      eae5 ncf1 #3
      binding aq #3
      fibα591 vim60 #3
      female immunoenzyme #3
      natural alleles genes #3
      immunization addition #3
      anticollagen antibody #3
      model arthritis #3
      human cii #3
      complex autoimmune diseases #3
      anticollagen antibodies #3
      rheumatoid arthritis complement #3
      antigen monoclonal arthritis #3
      macrophages involvement #3
      pia #3
      c2ta #3
      antibodies citc1iii #3
      patients monoclonal chimeric #3
      ciic1 cii #3
      hydrocarbon oils #3
      pnippam #3
      disease risk subsets #3
      hladrb104 cochranmantelhaenszel test #3
      neutrophil cytosolic factor #3
      class antigens keratinocytes #3
      chromosome eae17 #3
      cbrh7919 cells #3
      low production #3
      presence drb104 #3
      dual manner #3
      ctla4 adult mice #3
      rodents6 #3
      hladrb104 mann whitney #3
      citc1iii filaggrin #3
      pathogenesis pia #3
      pfp mice #3
      response immune response #3
      levels fibα591 #3
      acpa titers #3
      eae17 genetic heterogeneity #3
      activated cells mice #3
      day disease duration #3
      nadph oxidase complex #3
      acpas human serum #3
      multiple sclerosis hladr2 #3
      occurrence subspecificities #3
      cvrelated death association #3
      rt11 rats #3
      eae5r1 #3
      cii elisa #3
      subspecificities occurrence #3
      total abrogation #3
      major cell epitope #3
      mca ean #3
      role ros #3
      acpas genetic factors #3
      il‐4‐deficient mice #4
      cells maternal origin #4
      placental mhc #4
      citrullinated peptides autoantibodies #4
      α1ii chain #4
      ethylene isosteres #4
      interaction monoclonal antibody #4
      tcell activation development #4
      positional cloning genes #4
      parathyroid antibodies #4
      type collagen arthritis #4
      experimental arthritis cii #4
      cia6 #4
      cia mouse #4
      sh3gl1 #4
      mhc eae #4
      fibβ62 #4
      mrl dth #4
      congenic c57bl #4
      affinity case #4
      immunodominant cell #4
      bxsb chromosome #4
      cellular transfer #4
      epitope collagen #4
      arthritis severity #4
      immune response cii #4
      cia b10q mice #4
      elevated th1 #4
      citrullinated protein antibodies #4
      rheumatoid arthritis rats #4
      cryogel matrix #4
      mice etoposide #4
      adjuvant oil #4
      pathogenic antibody #4
      antigen sequence deletion #4
      variance animals arthritis #4
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      mip mice #4
      genetic association vav1 #4
      k8 k8 mice #4
      autoimmune experimental phenotype #4
      dead cell remnants #4
      onset clinical arthritis #4
      diseases rheumatoid #4
      cyclic software #4
      type collagen rat #4
      strains arthritis #4
      lnchc #4
      catabolism kynurenine #4
      estrus cycling #4
      glend2 #4
      stages disease development #4
      macrophages mycobacteria #4
      anti‐t‐cell #4
      antitype collagen antibodies #4
      treg cells ctla4 #4
      type collagen autoimmunity #4
      collagen rheumatoid #4
      cd4 cells stage #4
      dae3 #4
      elimination cd8 cells #4
      rs682626 #4
      cia suppression #4
      smoking antibodies #4
      immunoglobulin deficient #4
      experimental genetic #4
      collagen type #4
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      pathogenesis histone #4
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      tsc mice #4
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      cii animal epitopes #4
      estrogen levels levels #4
      autoimmune mrl #4
      rp sle #4
      dth reaction #4
      fpr2 recognition #4
      collagen glycopeptides #4
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      dth mrl #4
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      collagen immune #4
      experimental cattle cells #4
      cii peptide #4
      pristane‐induced #4
      arthritis collageninduced arthritis #4
      multispecific antibodies #4
      peptide mbp #4
      glands sialadenitis #4
      krönke #4
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      cb10 fragment #4
      strain eae #4
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      antibodies citrullinated peptides #4
      cytosolic ros #4
      synovial endothelium #4
      mp‐lpr #4
      candidate genes rats #4
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      tnfα p38 mapk #4
      antibody response mog #4
      genistein addition #4
      estrogen cia #4
      subsets presence #4
      inpp4b474r 548p #4
      ox8 #4
      development sialadenitis #4
      type‐ii collagen #4
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      cia lia #4
      species regulate #4
      inbred dba peptides #4
      cii ifa #4
      c129s #4
      congenic rats rats #4
      experimental arthritis humans #4
      cathelicidins ll37 #4
      mrl b6 #4
      locus mouse chromosome #4
      rs12979659 #4
      ii‐induced #5
      measurement nox activity #5
      chick cii #5
      patients acpa levels #5
      streptococcus pyogenes ides #5
      ovalbumin pepsin #5
      b‐cell epitope #5
      classical adjuvant #5
      arthritis onset #5
      tsst1producing #5
      raloxifene disease activity #5
      interaction cartilage #5
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      apc cii #5
      oxidative radicals #5
      immunized animals controls #5
      regulating rat #5
      subsets rheumatoid arthritis #5
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      cartilage type #5
      multiplex analyses #5
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      dba 1 mice #5
      nox complex #5
      commonly model #5
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      oestradiol vehicle #5
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      autologous type #5
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      overexpression hdac3 #5
      swr mouse #5
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      collageninduced arthritis cia #5
      delayed immunization rats #5
      severe arthritis mice #5
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      eae5 #5
      pineal gland development #5
      glycopeptide #5
      lethal inflammatory disorder #5
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      nox o2• h2o2 #5
      il4deficient mice #5
      type collagen cix #5
      ros mca #5
      egfp flow cytometry #5
      cgd hyperinflammation #5
      beta 11 cells #5
      tlr3 macrophages #5
      nox animal models #5
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      puccetti #5
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      rt1eu #5
      cia model #5
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      dba mouse #5
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      oia #5
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      aureus arthritis #5
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      mrvalues #5
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      avridineinduced arthritis #5
      absence c5 #5
      o2• h2o2 nox #5
      monoclonal antibody alpha #5
      tbb infection #5
      low dose tolerance #5
      collagen anti #5
      citrullinated peptides #5
      tubule cells kidney #5
      hydroxynorvaline #5
      immunological involvement #5
      cia cd4 cells #6
      acpa specificities #6
      peptides arthritis #6
      mice investigated #6
      immunization peptides #6
      cells affinity surface #6
      dominant suppression #6
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      autoimmune experimental genes #6
      murine loci #6
      female lymphocyte #6
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      glycoproteins nadph #6
      recombinant rat interferongamma #6
      betaoestradiol #6
      experimental postmenopausal #6
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      ltab #6
      pyramidal neurons loss #6
      mice congenic #6
      loci controlling #6
      igg autoantibodies sera #6
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      eae mhc #6
      pv loss #6
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      contrasting roles #6
      joints rats #6
      rheumatoid arthritis collagen #6
      transgenic mice arthritis #6
      collagen cia #6
      k8 mice #6
      induced psoriasis #6
      relapsing polychondritis rp #6
      mhcii alleles #6
      develop arthritis #6
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      tsst1 mice #6
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      rheumatoid arthritis comp #6
      mrna tgfbeta #6
      glycopeptide specificity #6
      collagen cells #6
      active arthritis #6
      erosive polyarthritis #6
      heterogeneous stock mice #6
      affinity ligand protein #6
      monoclonal encephalomyelitis autoimmune #6
      controls arthritis #6
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      staphylococcus aureus arthritis #6
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      arthritis autoantibodies #6
      treatment oestradiol #6
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      b10 mouse #6
      rcramp #6
      cia26 #6
      arthritis antibodies #6
      l3t4positive cells #6
      lys270 #6
      cell recognition #6
      complex mhc #6
      knockout receptors igg #6
      arthritis models #6
      rheumatoid arthritis model #6
      pathogenic events #6
      impact cia #7
      congenic mouse #7
      type collagen #7
      locus chromosome #7
      symptoms disease onset #7
      nonarthritogenic #7
      collagen arthritis cia #7
      antibodies citrullinated antigens #7
      cia mice #7
      response immunization #7
      raassociated molecules #7
      cii anti #7
      autoimmunity collagen #7
      effector phase #7
      polychondritis relapsing #7
      cryogel column #7
      macrophages alternative activation #7
      induction arthritis #7
      castrated females #7
      ean animals #7
      hydrolases polymorphism #7
      antibodyinduced arthritis #7
      rats phases #7
      isomerase peptide #7
      cia5 #7
      snecs #7
      psoriasiform skin disease #7
      g6pi #7
      mice constant darkness #7
      oestrogen rats #7
      impaired induction #7
      mbp peptide #7
      arthritis type collagen #7
      citrullinated peptide antigens #7
      congenic strains #7
      rheumatoid arthritis role #7
      ciireactive cells #7
      animal immunization injections #7
      yaa gene #7
      autoantibodies citrullinated peptides #7
      collagen epitope #7
      acpa titres #7
      autoantibodies lymphocytes #7
      aplec #7
      conventional environment #7
      periodontitis arthritis #7
      3xi #7
      cii apc #7
      cab3 #7
      strains disease #7
      regulatory cells macrophages #7
      arthritis genes #7
      mediated vasculitis #7
      transgenic class #7
      collagen arthritis rats #7
      autoimmune human #7
      analysis crosses #7
      murine psoriasis #7
      responses cii #7
      role raloxifene #7
      arthritis strains #7
      glycosylated collagen #7
      region syntenic #7
      chronic phase arthritis #7
      cognate activation #7
      chronic experimental #7
      mouse collagen #7
      protective influences #7
      antigens differentiation arthritis #7
      experimental autoimmune disease #8
      polymeric cryogels #8
      sialadenitis mrl #8
      clinical signs ean #8
      non‐mhc #8
      antibody vivo #8
      neutrophil cytosolic #8
      autoimmune congenic mice #8
      medium mem #8
      t‐cell priming #8
      autoantibodies subset #8
      cosphox #8
      typeii collagen #8
      fcγr2b #8
      autologous peptide #8
      antigenspecific priming #8
      cia2 #8
      eae3 #8
      incidence cia #8
      chronic autoimmune arthritis #8
      mumt mice #8
      b10 background #8
      hladrb11001 #8
      persistent joint pain #8
      oxidized peptides #8
      rt1f #8
      ptpn22620w #8
      experimental binding #8
      α1‐microglobulin #8
      supermacroporous cryogel #8
      destructive effects #8
      humans experimental arthritis #8
      onset incidence #8
      chromosomes loci #8
      diseases loci #8
      heterologous peptide #8
      treatment monoclonal #8
      ifa cii #8
      hlase alleles #8
      mice ifnbeta #8
      ros interplay #8
      cia animal model #8
      hdac3 expression #8
      arthritis lymphocytes #8
      mice techniques #8
      dominant cell epitope #8
      onset day day #8
      42 rats #8
      rheumatoid chromosome #8
      mbp mog #8
      induced neuropathology #8
      antibodies acpas #8
      illness igg #8
      underlying genes #8
      rheumatoid autoimmunity #8
      parathyroid glands receptors #8
      murinised #8
      rats mhc #8
      inflamed synovia #8
      haematogenously #8
      hybridomas antibodies #8
      expression hdac3 #8
      eae genetic encephalomyelitis #8
      patients type collagen #8
      oia2 #8
      297 cases #8
      lyme arthritis severity #8
      murine locus #8
      autoantibodies collagen type #8
      collagen female #9
      eae immunization #9
      experimental genes #9
      rt1u #9
      mammalian disease models #9
      murine collagen #9
      arthritis cross #9
      arthritis skg mice #9
      differentiation autoimmune #9
      posttranslational glycosylation #9
      hgpi325 #9
      idiotype‐specific #9
      nodp #9
      illness receptor #9
      oil adjuvants #9
      avridine #9
      antibody alpha #9
      response mouse #9
      serum interferon #9
      il10 role #9
      reduced arthritis #9
      early joint erosions #9
      bound carbohydrates #9
      loci rats #9
      rats rat #9
      acpas #9
      human immunopeptidome #9
      collagen complement #9
      induced metabolic syndrome #9
      antibodies vivo #9
      b10riii mice #9
      animal models urgent #9
      psychological tyrosine #9
      hitr #9
      disease strains #9
      cia transgenic mice #9
      mouse peptide #9
      rheumatoid autoantibodies #9
      variants acpa #9
      acpas patients #9
      bovine cii #9
      inbred dba mice #9
      specific nox2 #9
      pristane #9
      intranasal animals arthritis #9
      experimental arthritis rats #9
      histone 1 hdac1 #9
      development autoimmune arthritis #9
      adaptive inflammation #9
      ox19 #9
      alpha1inhibitor3 #9
      ean myelin #9
      rheumatoid joints #9
      specific sets #9
      oligomeric matrix #9
      postmenopausal arthritis #9
      effects mabs #9
      inbred lew tlymphocytes #9
      2 nadph #9
      class allele #9
      patients acpas #9
      autoimmunogenic #9
      mutated mice #10
      alpha collagen chains #10
      h2ap #10
      o2• h2o2 #10
      inbred dba #10
      cartilage collagen fibrils #10
      antibodies specific #10
      cartilage oligomeric #10
      mice nadph #10
      monoclonal arthritis #10
      mbp peptides #10
      nih heterogeneous stock #10
      tertbutylacrylamide #10
      oestrogen #10
      acpa diagnosis #10
      monoclonal antigens rats #10
      rheumatoid arthritis dr4 #10
      presence acpa #10
      cartilage arthritis #10
      activation male #10
      stock mice #10
      development severity #10
      ifnbeta mice #10
      collagen autoimmunity #10
      animal models #10
      experimental cartilage #10
      cells increased production #10
      severe erosive #10
      citrullinated antigen #10
      beta 11 #10
      endogenous collagen #10
      pain animal models #10
      immunization rats #10
      axotomized motor neurons #10
      passive transfer experiments #10
      extracellular cartilage #10
      mice genistein #10
      dense fractions #10
      antibody collagen #10
      mice cii #10
      cells development #10
      cd4 cells spleen #10
      cii mice #10
      acutephase response rats #10
      knockout nadph #10
      rats lewis rats #10
      hlase smoking #10
      genetic experiments #10
      autoimmune disease humans #10
      cell‐deficient #10
      abp gene #10
      onset chromosome #10
      reactivity acpas #10
      native collagen type #10
      prl effects #10
      development rheumatoid #11
      gad6 #11
      isotypes #11
      rat liver rats #11
      mice mhc #11
      ptpn22 smoking #11
      chronic arthritis #11
      potential autoantigens #11
      species respiratory #11
      tailbase #11
      nodb10h2b mice #11
      cia7 #11
      dss wt #11
      naïve cells cells #11
      loci regulating #11
      mice cd1 #11
      antigen variability #11
      liver receptor lxrα #11
      cia30 #11
      2xi #11
      rat arthritis #11
      chondrocytes ecm #11
      antibody type collagen #11
      inflammatory arthritis role #11
      rat collagen #11
      individuals onset #11
      monoclonal rheumatoid factors #11
      cells pia #11
      84–102 #11
      stromal cells macrophages #11
      antibodies association #11
      fragments anti #11
      arthritis absence #11
      mhc control #11
      lentiviral vector expression #11
      autoimmune monoclonal antigens #12
      nonselfdiscrimination #12
      pia1 #12
      chronic erosive arthritis #12
      natural polymorphism #12
      role arthritis #12
      encephalomyelitis induced #12
      major haplotype #12
      cell responses cii #12
      cross rats #12
      qa2 #12
      psoriasis arthritis #12
      myelin ean #12
      icmediated #12
      rats cia #12
      stages pathogenesis #12
      structure antibodies #12
      cii patients #12
      natural loss #12
      serum concentrations comp #12
      antibodies structures #12
      loci disease #12
      backgroundantibodies #12
      mice comp #12
      animal immunohistochemistry #12
      matrilin #12
      mbp response #12
      peptide study #12
      onset symptoms #12
      treatment experimental arthritis #12
      associations antibodies #12
      stage cia #12
      immunodominant #12
      genetic contamination #12
      frequencies antibodies #12
      rats expression #12
      increased litter size #12
      riiis #12
      mutation nadph #12
      mutated mouse #12
      hydroxylysines #12
      lung macrophages mice #12
      illness sex characteristics #12
      lymphoid cells development #12
      type collagen immunization #12
      bovine type collagen #12
      α1ii #12
      study arthritis #12
      psoriasis mouse model #12
      reduces severity #12
      fpr2 agonists #12
      immunohistochemistry interferon #13
      idd5 #13
      joints blood #13
      advanced intercross #13
      mannan #13
      bcelldeficient mice #13
      l012 #13
      rfigg #13
      ho4 #13
      genes mouse chromosome #13
      macroscopic scoring #13
      species deficiency #13
      mouse strains #13
      levels nabs #13
      anticii #13
      μ chain #13
      citrullinated #13
      b10p #13
      cell epitope #13
      mtec aire #13
      antibodies citrullinated proteins #13
      t‐cell epitope #13
      24dinitro1fluorobenzene #13
      cells salivary glands #13
      native type collagen #13
      lew1w #13
      expression egfp #13
      arthritis knowledge #13
      complement complement activation #13
      strains incidence #13
      epitope immunization #13
      development type collagen #13
      behavioral alterations rats #13
      nos2derived #13
      cyclic citrullinated #13
      oxidase nox2 #13
      doses ici #13
      ccp2 antibodies #13
      major loci #13
      dr1 transgenic #13
      sequence collagen #13
      oxidative regulation #13
      nonobese diabetic mouse #13
      multispecific #13
      hladrb1 ptpn22 #13
      factor isotypes #13
      dba molecular #13
      macrophages immune response #14
      osteoclasts vivo #14
      nasal inhalation #14
      candidate autoantigens #14
      arlacel #14
      blymphocyte female humans #14
      smallmolecule compound #14
      cia expression #14
      murine collageninduced arthritis #14
      specific inflammation #14
      arthritic paws #14
      protein collagen #14
      sirt1 mmp9 #14
      antifilaggrin antibodies #14
      presence mcv #14
      autoimmunity animals #14
      molecular disease models #14
      collagen comp #14
      immunized rat #14
      peptides anti #14
      mhc class region #14
      efficient promotion #14
      humans nadph #14
      loci interaction #14
      loci rheumatoid #14
      collagen disease #14
      gut protection #14
      aggregated nets #14
      deficient production #14
      thr233 #14
      experimental interferon #14
      immune regulators #14
      autoimmune arthritis #14
      involvement cells #14
      b6n mice #14
      rheumatoid arthritis presence #15
      type collagen development #15
      rt1a #15
      rat genetics #15
      dcii #15
      involvement pathogenesis #15
      regulation adaptive immunity #15
      translationally modified #15
      ros cii #15
      arthritis role #15
      exaggerates #15
      antigenic epitope #15
      monoclonal arthritis rats #15
      lentiviral gene delivery #15
      osteoporosis development #15
      polychondritis #15
      anticollagen #15
      raloxifene estradiol #15
      arthritis development #15
      mhc class molecule #15
      presence anticarp antibodies #15
      citrullinated peptides patients #15
      mice type collagen #15
      congenic rats #15
      murine cia #15
      2 weight #15
      cultured human chondrocytes #15
      immune complex formation #15
      rats monoclonal antigens #15
      experimental allergic neuritis #15
      treatment cia #15
      cdr regions #15
      tflask #15
      antibodies arthritis #15
      nodb10h2b #15
      mice immunization #15
      amps development #15
      monolithic cryogel #15
      neuritis rats #15
      integrated bioprocess #15
      apcs macrophages #15
      aire mtec #15
      epitopes mice mice #16
      anti‐t #16
      development rheumatoid arthritis #16
      matrilin proteins #16
      rt1 #16
      males onset #16
      fewer osteoclasts #16
      rno10 #16
      mhcii ciita #16
      h2p #16
      antinuclear autoimmunity #16
      cep1 #16
      levels natural antibodies #16
      indirect genetic predisposition #16
      n305 #16
      lethal inflammatory #16
      rats experimental arthritis #16
      hla–drb1 shared epitope #16
      autologous collagen #16
      pparγ lxrα #16
      class transplantation #16
      rheumatoid factor production #16
      subspecificities #16
      oligomeric matrix protein #16
      disease mice mice #16
      acute inflammation mice #16
      mumt #16
      genes animals #16
      nonglycosylated form #16
      congenic mice mice #16
      staphylococcal arthritis #16
      mhc genes #16
      rheumatoid arthritis genes #16
      lew1 #16
      arthritis cii #16
      arthritis severity mice #16
      allergic neuritis #17
      polyphosphate4 #17
      cartilage collagen #17
      mice rheumatoid arthritis #17
      leuphe #17
      arthritis rheumatoid autoantibodies #17
      human fcγriia #17
      cells collagen #17
      ethanol development #17
      genistein mice #17
      clever1 #17
      periodontitis antibodies #17
      spleen peyers patches #17
      rats lewis #17
      nox2 derived #17
      rt1av1 #17
      animals congenic #17
      inbred lew #17
      progesterone development #17
      native denatured #17
      cab4 #17
      skg #17
      cells female mice #17
      rheumatoid arthritis subsets #17
      collagen induced arthritis #17
      collagen specific #17
      strains lymphocytes #17
      triplehelical conformation #17
      onset rheumatoid arthritis #17
      cells presenting cells #17
      hybridomas mice mice #18
      moginduced eae #18
      short‐term administration #18
      joint inflammatory #18
      genes spleen #18
      salivary glands mice #18
      h2z #18
      phenotypic feature #18
      addition ros #18
      disease duration onset #18
      dra0101 #18
      day arthritis #18
      langerhans cells cells #18
      cuiiida #18
      ealkene #18
      purified anti #18
      anti cd44 #18
      ros data #18
      humanized transgenic mice #18
      keratinocytes induction #18
      autoimmune illness #18
      adjuvant arthritis rats #18
      arthritis anti #18
      galactose moiety #18
      day immunization #18
      collagen autoantibodies #18
      expression lxrα #18
      cartilage type collagen #18
      defined epitope #18
      elisa cia #19
      citrullinated proteins acpa #19
      suppression dth #19
      supermacroporous #19
      future utility #19
      vivo elimination #19
      tbetarii gene #19
      rats snp #19
      cia eae #19
      inflammatory attack #19
      collagen response #19
      mice develop #19
      gly262 #19
      blood monocytes neutrophils #19
      beta oestradiol #19
      cd4 transgenic #19
      new avenues #19
      trimolecular complex #19
      peyers patches spleen #19
      mrl mp mice #19
      single intradermal injection #19
      protective alleles #19
      three‐dimensional culture #19
      castrated female rats #19
      patients polychondritis #19
      mice congenic mice #19
      protein comp #19
      ncr3 #20
      imaging reactive #20
      mbp rats #20
      progesterone oestrogen #20
      mice cia #20
      role nox #20
      knockout mice transgenic #20
      pvg1av1 #20
      rt1d #20
      serm raloxifene #20
      development disease #20
      5p14 #20
      monkeys rodents #20
      highly susceptible #20
      loci chromosomes #20
      human rheumatoid arthritis #20
      underlying gene #20
      glycosylated #20
      antibody treatment #20
      mhc class alleles #20
      prominent infiltration #20
      littermate #20
      enhanced tcr #20
      5r5 #20
      ciita mhcii #20
      nox1deficient mice #20
      inflammation mice #20
      stress phospholipids #20
      experimental autoimmunity #20
      matrilin1 #20
      response mbp #20
      fls tnfα #20
      onset severity #21
      rats development #21
      ean rats #21
      igg fcgammar #21
      n141 #21
      nitratenitriteno pathway #21
      muscle ros #21
      arthritis pregnancy #21
      cells adaptive immune #21
      chronic relapsing #21
      α1acidglycoprotein #21
      diseases lymphocytes #21
      suppressor cytotoxic cells #21
      linomide treatment #21
      olahsd #21
      serum levels comp #21
      nox2 activity #21
      pathogenesis rheumatoid #21
      supermacroporous cryogels #21
      cia treatment #21
      individual acpa #21
      granule mobilization #21
      positional cloning #21
      illness autoimmune #21
      triplehelical peptides #21
      nox2 mice #21
      genes controlling #21
      experimental rheumatoid #21
      conserved haplotype #21
      drb11001 #21
      mice mutant strains #21
      n286 #21
      animal epitopes humans #22
      identification susceptibility genes #22
      samples onset #22
      experimental phenotype #22
      mice independent #22
      cultured hepatic cells #22
      antiidiotypic antibody #22
      ccp negative #22
      induced eae #22
      rats nonalcoholic steatohepatitis #22
      determinant selection #22
      semiallogenic #22
      rats loss #22
      270 #22
      association pv #22
      vh j558 #22
      response myelin #22
      c57bl mice subfamily #22
      ul1 #22
      81a #22
      citrullinated epitopes #23
      citrullinated antigens #23
      inflammation absence #23
      cells b10 #23
      mace association #23
      arthritis type #23
      lymphocytes amino #23
      tgfbeta resistance #23
      loss collagen #23
      peptide activation #23
      mbp eae #23
      anti‐cd5 #23
      onset cia #23
      complex influences #23
      citrullinated protein #23
      17 betaoestradiol #23
      castration rats #23
      phage clones #23
      immunopeptides #23
      comp #23
      monoclonal antigens autoimmune #23
      experimental autoimmune diseases #23
      antibodies acpa #23
      cryogel beads #23
      diseases autoimmunity #23
      cells presentation #23
      animal genes #23
      4npa #23
      rats inbred lew #23
      b10r #23
      experimental chromatography #23
      levels comp #24
      loci chromosome #24
      ftirm #24
      mediated arthritis #24
      339 #24
      experimental lupus #24
      mouse models development #24
      c57bl 10 mice #24
      mice nox2 #24
      autoantibodies rheumatoid #24
      inflammation arthritis #24
      antinuclear apoptosis #24
      rat induction #24
      y35 #24
      animal epistasis #24
      secondary immune response #24
      subloci #24
      monoclonal anti #24
      experimental cells #24
      chronic autoimmune diseases #24
      severity ali #24
      controls anti #24
      flss patients #24
      severity chronicity #24
      postpartum flare #24
      new mouse #24
      cells c3h #24
      rno4 #25
      collagen cartilage #25
      congenic animals #25
      inbred lew rats #25
      monocytes nadph #25
      b6 balb #25
      massive infiltration #25
      tolerized rats #25
      immunodominant epitope #25
      autoimmune diseases humans #25
      production monoclonal #25
      beta lymphocytes #25
      8 antibodies #25
      murine lyme arthritis #25
      bnda #25
      specific epitopes #25
      complex male #25
      autoantibody response #25
      common autoimmune disease #25
      arthritis experimental arthritis #25
      proteinarginine deiminase type #25
      parasitemia survival #25
      immunization development #25
      ros #25
      cix #25
      arginine arthritis #25
      rat mhc #25
      autoimmune messenger #25
      cell hybridomas #25
      relapsing polychondritis #25
      interleukin2 mice receptors #25
      cells immunization #25
      cells joints #26
      cb11 #26
      viable chondrocytes #26
      eae development #26
      autoantibodies citrullinated proteins #26
      gene regions #26
      anti citrullinated #26
      nitrophenylalanine #26
      igg2a mice #26
      polychondritis rp #26
      local exposure #26
      mice gammadelta cells #26
      post translationally #26
      glutamax #26
      helperinducer animals antibodies #26
      granulocytes cells #26
      hydrocarbon oil #26
      disease immunoglobulin #27
      ccp2 #27
      interleukin21 tlymphocytes #27
      rheumatoid factor isotypes #27
      innate interleukin10 #27
      individuals antibodies #27
      c1i #27
      perforin deficiency #27
      physiological level #27
      intercrossed #27
      immunodominant response #27
      trypsination #27
      antibodies type #27
      immunospecific #27
      hladrb1 shared epitope #27
      pointmutation #27
      pannus tissue #27
      nonmhc genes #27
      protein peptides #28
      w3 25 #28
      chronicity #28
      ros induction #28
      eae susceptibility #28
      rat strain #28
      animal models neurodegeneration #28
      antily6g #28
      anti rat #28
      lysine position #28
      nr8383 #28
      mediated effects #28
      mrna ifngamma #28
      cia3 #28
      cartilage vivo #28
      upregulation cytokines #28
      onset day #28
      antigenspecific tolerance #28
      antibodies mab #28
      severity day #28
      autoimmune inflammatory #28
      membrane lymphocytes #29
      246trinitrophenyl #29
      immunopathogenicity #29
      smoking presence #29
      cfa cia #29
      ls2616 #29
      mice mab #29
      hiit exercise #29
      antibody producing cells #29
      parotid secretory protein #29
      presence synovial fluid #29
      rfigm #29
      ros production macrophages #29
      phenomes #29
      glucose transport capacity #29
      suboptimal doses #29
      chronic dss #29
      acpa #29
      absence inflammation #29
      peptide anti #29
      development experimental #30
      chain collagen #30
      hlase #30
      alphabetat #30
      linkage disease #30
      synovial cells patients #30
      paws #30
      vgenes #30
      vpba #30
      adult thymectomy #30
      treatment raloxifene #30
      increased salt #30
      ctla4 mice #30
      disease immunity #30
      11 cells #30
      translational rats #30
      acpa fine #30
      metabolic syndrome rats #30
      vivo exercise #30
      variable heavy chain #30
      cultivation cells #30
      dba mice #30
      chronic autoimmune #30
      plasminogendeficient mice #30
      monoclonal antibody production #31
      drugs addition #31
      disease development #31
      littermate controls #31
      synovial fluid blood #31
      phytol #31
      psoriasis model #31
      pristaneinduced lupus #31
      nox2 nox1 #31
      ige cd23 #31
      acute‐phase response #31
      trimolecular #31
      rats autoimmune #31
      common chain #31
      selfprotein #31
      human type collagen #31
      comparative genetic analysis #31
      hiit training #31
      expressing cells #31
      perpetuated #31
      apc development #31
      immunization #31
      steen #32
      cells uterus #32
      beta mice #32
      ros rns #32
      epitope antibodies #32
      presence acpas #32
      cell ratio #32
      nadph oxidases nox #32
      bound peptides #32
      genomewide genotyping #32
      type antibody #32
      mucosal tolerance #32
      ra33 #32
      methods serum samples #32
      rt11 #32
      differentiation arthritis #32
      specificity function #32
      11 cell #32
      h2aq #32
      congenic mice #32
      arthritis therapy #32
      influence genes #32
      polymorphic genes #32
      hladrb104 #32
      receptor preference #32
      nonb cells #32
      caia mice #32
      acpa rheumatoid arthritis #32
      role osteoclastogenesis #32
      nodes mice #32
      arthritic mice #33
      cytosolic factor #33
      multiplex analysis #33
      autoantibody activity #33
      delayed type #33
      role vav1 #33
      skews #33
      tcell receptor #33
      epitopes antibodies #33
      rheumatoid joint #33
      type cross #33
      antigenpresenting cells cells #33
      tolerance immunization #33
      modified collagen #33
      autoimmune demyelinating disease #33
      induced immunization #33
      c4bp #34
      fpr1 #34
      patients animal models #34
      chronic polyarthritis #34
      interferon activity #34
      natural antibodies nabs #34
      heterogeneous stock #34
      cells dendritic cells #34
      neurodegeneration role #34
      promiscuous expression #34
      joint pathology #34
      nox2 deficiency #34
      monoclonal rheumatoid #35
      plasminogen deficiency #35
      1xi #35
      hybridomas #35
      major regulators #35
      complex arthritis #35
      autoreactive #35
      nets neutrophils #35
      antirat #35
      psoriasiform skin #35
      triple helical #35
      destructive arthritis #35
      acs stroke #35
      accessible sites #35
      development chronic #35
      patients populations #35
      infectious disease models #35
      antiarthritis #35
      arthritis disease #35
      phagotope #35
      vdr cells #35
      techniques mice #36
      female histocompatibility #36
      cii cfa #36
      oxidases rna #36
      h2r #36
      animals antigen #36
      nk cells recognition #36
      arthritis cartilage #36
      tolerance tlymphocytes #36
      induction tregs #36
      cartilage joints #36
      dth #36
      flow cytometry expression #36
      dinitro1 #36
      phagocyte #36
      specificity sera #36
      h2g7 #36
      comparative genetics #36
      variance animals antibodies #36
      protein specific #36
      immunopathological features #37
      spontaneous arthritis #37
      synthetic glycopeptides #37
      dba1 #37
      acpa positive #37
      role gamma interferon #37
      cii protein #37
      c129 #37
      lymphocytes disease #37
      rich lipid #37
      encephalomyelitis #37
      mif pathogenesis #37
      joint cartilage #37
      peptides binding #37
      oxidases oxidation #37
      recombinant vaccine #37
      genetic control #37
      susceptibility autoimmune diseases #37
      cldn4 #38
      target autoantigens #38
      animal models pain #38
      cochranmantelhaenszel test #38
      antibodies animals #38
      human blood neutrophils #38
      nitrogen species #38
      sialophorin #38
      snat #38
      innovative tools #38
      clonal expansion cells #39
      acpa response #39
      oestrogen treatment #39
      benoist #39
      ccia #39
      data myelin #39
      resultsrats #39
      cell tolerance #39
      b6n #39
      nzw #39
      endoβnacetylglucosaminidase #39
      nfr #39
      ym1 #39
      measurement activity #39
      autoreactive cells #39
      wasting syndrome #39
      allogeneically #39
      peptide cell #40
      positive rheumatoid #40
      isostere #40
      addition impact #40
      polyclonal cell activation #40
      adjuvant induced #40
      disease animal models #40
      genetic complexity #40
      rt1c #40
      antigens arthritis #40
      autoimmune inflammatory diseases #41
      autoimmune #41
      mhc haplotype #41
      immunocap isac #41
      priming phase #41
      rats anti #41
      aq #41
      severity incidence #41
      effects experiments #41
      genes loci #41
      rat myelin #41
      congenic mapping #41
      ncii #41
      th17 axis #42
      species receptors #42
      expected onset #42
      articular collagen #42
      pineal gland melatonin #42
      drb1 shared #42
      mhc class class #42
      spleen weight #42
      p38 mapk nfκb #42
      cartilage bone destruction #42
      fibroblasts mice #42
      antibody isotypes #42
      ptpn22 locus #42
      treatment autoimmune diseases #43
      congeneic #43
      type‐ii #43
      cd11bly6g #43
      lew lymphocytes #43
      anticitrullinated #43
      crosses genetic #43
      arthritis data #43
      kgf treatment #43
      anticyclic #43
      immunodominant epitopes #43
      spinal glia #43
      collagen #43
      mice autoimmune #43
      lew rats #43
      autoreactive cell #43
      rats sex #43
      pc8 #43
      provocations #44
      mathis #44
      mice adulthood #44
      c4bbinding protein c4bp #44
      peptide induced #44
      chloro23 #44
      defensins humans #44
      genetic linkage analysis #44
      inflammation animals #44
      mice mice autoimmune #44
      epitopes lymphocyte #44
      addition order #44
      neuritis ean #44
      homozygous form #44
      relapsing disease #45
      potent suppression #45
      susceptibility arthritis #45
      phagotopes #45
      nzb #45
      genetic encoding #45
      outbred rats #45
      disease histocompatibility #45
      chromosome development #45
      disease induction #46
      affinity purified #46
      posttranslationally #46
      lower severity #46
      specific tolerance #46
      c227 #46
      cocrystallisation #46
      eae mbp #46
      rat2 #46
      alphachains #46
      neuritis autoimmune #46
      carp antibodies #46
      isosteres #46
      locus controlling #46
      mhc class humans #46
      rheumatoid factors #47
      diagnostic accuracy diagnosis #47
      f1 hybrid mice #47
      association hladrb1 alleles #47
      antibody reactivities #47
      intercrosses #47
      idiotypic antibody #47
      complex mediated #47
      posttranslational rats receptors #47
      protective allele #47
      humanized model #48
      peptide recognized #48
      acetylchitobiose #48
      experimental arthritis mice #48
      f1 crosses #48
      synovial lining layer #48
      mice nzb #48
      γchains #48
      mice carrying #48
      tlr12 #48
      antibody specificity #48
      cia rats #48
      collagen glycosylation #48
      collagen peptide #48
      lupus disease #48
      comp levels #49
      tcell stimulation #49
      experimental crosses #49
      histone hdacs #49
      class major #49
      immune nervous #49
      mouse cartilage #49
      sex genes #49
      monoclonal autoimmune diseases #49
      mice caia #49
      polyvinylcaprolactam #49
      bystander activation #49
      parathyroid cells #50
      antigenantibody #50
      inflammation kynurenine #50
      animal cell culture #50
      glycosylated form #50
      glutamine uptake #50
      complex region #50
      disease rats #50
      monoclonal epitopes #50
      loci animals #50
      cytometry analyses #50
      anticarbamylated protein #50
      dependent chronic #50
      mice tolerance #50
      alagly #50
      ciiia #50
      delayed immunization #51
      runting #51
      antibodies cells #51
      evidence animal models #51
      c57bl 6j background #51
      inbred c57bl autoimmune #51
      autoantibodies rheumatoid arthritis #51
      lentiviral particles #51
      tolerized #51
      tracheal cartilage #51
      rheumatoid factor activity #51
      cells ova #51
      fewer cells #51
      aire mice #51
      derived type #51
      antigenpresenting cells #52
      model collagen #52
      macrophages skin #52
      ptpn22 #52
      xor activity #52
      matrix protein #52
      protein antibodies #53
      antibodies epitopes #53
      production reactive #53
      lysosomal compartments #53
      cartilage erosion #53
      physiological doses #53
      triple helical structure #53
      carbamylated proteins #53
      patients rheumatic conditions #53
      melatonin day #53
      arthritis induction #53
      gastric parietal cell #53
      induced autoimmunity #53
      aged peptides #53
      imitating #54
      melatonin animals #54
      strain rats #54
      carbamylated protein #54
      antigens myelomonocytic arthritis #54
      rats social isolation #54
      predating #54
      development individuals #54
      animals autoimmune #54
      yaa #54
      major epitope #54
      nodes lymphocyte #54
      crossbreeding #54
      complex genetic disease #55
      autoimmune reactions #55
      susceptibility autoimmune disease #55
      inflammatory manifestations #55
      arthritis genetic #55
      macrophage mannose receptor #55
      autoimmune nzb #55
      animals antibody #56
      cells salivary #56
      new animal #56
      alpha1microglobulin #56
      mhc #56
      selfreactive cells #56
      labels superoxide #56
      cd1 mice #57
      vivo depletion #57
      animals antirheumatic #57
      antibodies #57
      arthritis pathogenesis #57
      collagen sequence #57
      development autoimmune #57
      igg abs #57
      antibodies bind #57
      oestrogen progesterone #58
      rat type #58
      chronic eae #58
      urokinase activity #58
      schafer #58
      peptide response #58
      hydroxylase diet #59
      anticarp antibodies #59
      resistance eae #59
      anti cd8 #59
      genes mhc #59
      oligoclonal igg bands #59
      anti cell #59
      articular joints #59
      cartilage matrix protein #59
      encephalitogenicity #59
      joint erosions #60
      assay epitopes #60
      hpaaxis #60
      macrophage mannose #60
      inflammatory cells macrophages #60
      alternative activation macrophages #60
      protein peptide #60
      dichotomous effects #60
      immunohistopathology #60
      experimental evoked potentials #61
      differentiation myelomonocytic arthritis #61
      epitope spreading #61
      incidence severity #61
      major histocompatibility #61
      alpha1m #61
      serum comp #61
      experimental rats rats #61
      cells innate immune #61
      species reactive #61
      syngeneically #62
      cyclic sensitivity #62
      reduced oxidative #62
      basic characterization #62
      fpr2 #62
      interferon‐β #62
      adaptive immune #62
      antigens class histocompatibility #62
      mice susceptibility #62
      placenta uterus #62
      autoantibody formation #62
      toxin1 #62
      specificity tumor #63
      post‐partum #63
      glycoprotein myelin #63
      constant darkness #63
      collagen cell #63
      induced experimental #63
      mice polyi #63
      duval #63
      protein disease #63
      igaproducing cells #63
      delayed interferon #63
      specific stages #63
      peptide specific #63
      rats strain #63
      mog1 #63
      nadph oxidases #63
      hypersensitivity dth #63
      transfer animals #63
      freund adjuvant #64
      lower capacity #64
      role apc #64
      secondary immune #64
      maternal origin #64
      tolerance model #64
      hindpaws #65
      flss #65
      weight variation #65
      autoimmunity humans #65
      induced suppression #65
      histocompatibility complex #65
      major subset #65
      model chronic #65
      thy1 antigen #66
      hladr2 #66
      spontaneous disease #66
      experimental lymphocytes #66
      negative rheumatoid #66
      rheumatoid synovial cells #66
      multispecificity #66
      chromosomes mammalian #66
      phagocytosis oxidative burst #66
      peripheral joints #66
      acute arthritis #66
      resemblances #66
      mice induced #67
      endos #67
      myelomonocytic arthritis #67
      rheumatoid arthritis susceptibility #67
      experimental allergic #67
      development cell #67
      dendritic cells epitopes #67
      strains susceptible #67
      mice cell #67
      key interactions #67
      experimental encephalomyelitis #67
      fibrinogen genotype #67
      class region #68
      cells mhc class #68
      sodium diethyldithiocarbamate #68
      individuals positive #68
      frequent infections #68
      female sex hormones #68
      complex class #68
      tolerized mice #68
      helper phenotype #68
      anti carp #68
      rheumatoid chromosomes #68
      severity periodontitis #68
      iggrf #68
      direct damage #69
      rheumatoid disease #69
      relapsing #69
      lymphocytes chronic #69
      frequency antibodies #69
      cells mouse #69
      vertebrate immune #69
      zap‐70 #69
      translationally #70
      presence rheumatoid factor #70
      mrl mice #70
      prolonged graft survival #70
      response type #70
      immunoglobulin interferon #70
      role cells #70
      swr #71
      susceptibility female #71
      expression pparγ #71
      isolated rats #71
      ztm #71
      human psoriasis #71
      cartilage mice #71
      cb10 #71
      study antibodies #72
      autoimmunity lymphocytes #72
      antibodies binding #72
      interphalangeal joints #72
      naïve mice #72
      dark agouti rats #72
      lathyritic #72
      napdh #72
      delayedtype hypersensitivity dth #72
      knockout protein processing #73
      treatment stages #73
      type ifn signature #73
      environmental lighting #73
      oxidase complex #73
      membrane animals #73
      species ros #73
      mrl lpr #73
      bovine type #73
      igarf #74
      pregnancyinduced #74
      cartilage explants #74
      peptides sequences #74
      antigens class #74
      hypersensitivity delayed #74
      cell reactivity #75
      acpapositive #75
      inbred dba receptors #75
      effects development #75
      diabetes arthritis #75
      genetic disease models #75
      dth mice #75
      oestradiol #75
      peptide mhc #76
      type collagens #76
      disease rheumatoid arthritis #76
      anti carbamylated #76
      rat splenocytes #76
      pain inflammation #77
      nerve conduction velocity #77
      rats eae #77
      inbred mouse strains #77
      cyp7a1 #77
      eae induced #77
      regulatory vaccines #77
      rt1n #77
      cell deficient #77
      collagen chains #77
      new animal model #77
      lpr mrl #77
      oligomeric #77
      development insulitis #77
      rats respiratory #78
      mhc expression #78
      autoantigenic #78
      pythons #78
      pathogenesis rheumatoid arthritis #78
      cartilage integrity #78
      clinical arthritis #78
      mononuclear lung #79
      susceptibility disease #79
      inflammatory autoimmune #79
      1ii #79
      shared epitope #79
      autoimmune experimental epitopes #79
      chromosome study #80
      oxidases #80
      detection autoantibodies #80
      erosive arthritis #80
      hnrnpa2 #81
      estrogen suppression #81
      sex linkage #81
      spleen study #81
      mrl mp #81
      mog mbp #81
      dr1 antigen #81
      induced leukocyte #81
      type macrophages #81
      class antigen expression #81
      inflammatory phase #81
      expression ll37 #81
      aspartic acid position #81
      mhcii expression #81
      arthritis cells #81
      nadphoxidase #82
      pannus formation #82
      14weeks #82
      mice igg #83
      bcg infection #83
      cell independent #83
      expression mhc #83
      drug encephalomyelitis #83
      tlymphocyte genes #83
      arthritis day #84
      rat cardiac allografts #84
      spontaneous development #84
      strains animals #84
      epidermal cells #84
      reactive cells #84
      multiple sclerosis evidence #84
      naïve cells #84
      class molecule #85
      homopentamer #85
      antiifngamma #85
      inflammation joints #85
      inflammation joint #85
      knockout receptors #85
      cells recognize #85
      severe eae #86
      phagocyte nadph #86
      contribution genes #86
      gfoger #86
      monoclonal antibodies mab #86
      anti cd4 #86
      animal humans #86
      mutant strains #86
      preclinical stage #86
      classical humans #86
      smash #87
      estrogen induced #87
      inbred rat strains #87
      mhc class gene #87
      alpha1acid glycoprotein #87
      fine specificities #88
      narac #88
      copy variation #88
      inguinal lymph nodes #88
      levels anti #88
      thps #88
      depletion cd8 cells #89
      arthritic #89
      mice antibodies #89
      mabs mab #89
      genetic quantitative #89
      peptide immunization #89
      experimental autoimmune #89
      autoimmune inbred c57bl #90
      susceptible #90
      rheumatoid arthritis cells #90
      arthritis compared #90
      pineal hormone melatonin #90
      genistein treatment #90
      ilc2 activation #90
      adjuvant arthritis #90
      monkeys mice #90
      mediated mechanisms #90
      synovial fluid serum #91
      histological sections #91
      activation cd4 cells #91
      backgroundan #91
      protein induced #91
      cattle collagen #91
      cells apc #91
      abdominal region #92
      nod mhc #92
      experimental mouse models #92
      humans immunodominant #92
      difco #92
      anticitrullinated protein #92
      knockout myelin #93
      animals autoantibodies #93
      xor #93
      mice melatonin #93
      cellspecific #93
      natural polymorphisms #93
      290 patients #93
      fcγrs #94
      macrophages development #94
      activated cells cells #94
      autosomal genes #94
      galactosylated #94
      endosomal acidification #94
      chronic phase disease #95
      induced sarcoma #95
      binding integrins #95
      moderateintensity exercise #95
      nonglycosylated #96
      cell alpha #96
      messenger tolllike receptor #96
      macrophages stimulation #96
      romani #96
      data rats #96
      ifnbeta #96
      pregnancy disease #96
      lung emphysema #96
      fetal rejection #96
      complex mice #97
      il33r #97
      citrullinated fibrinogen #97
      cathelicidins #97
      hydroxylysine #97
      antiimmunoglobulin #97
      genetic female genes #97
      macrophages fibroblasts #97
      rheumatoid lymphocytes #97
      swr mice #98
      acpa igg #98
      autoimmune rats #98
      autoimmune experimental #98
      rheumatoid cartilage #98
      ean #98
      interleukin‐4 #99
      collagen cytokines #99
      alternative pathways #99
      rat chromosomes #99
      tlymphocyte immunity #100
      invading pathogens #100
      ccp anti #100
      peptides cells #100
      protein antibody #100
      thy1 antigens #100
      cultured crosses #100
      inducer animals #100
      rats monoclonal antibodies #100
      tap2 #100
      diarthrodial #101
      singlenucleotide polymorphism #101
      eira #101
      susceptible strain #101
      cell determinants #101
      safety drugs #101
      bone degradation #101
      fprs #101
      eae animal encephalomyelitis #102
      mouse monoclonal antibodies #102
      candidate autoantigen #102
      brucei infection #102
      findings treatment #102
      pathogenesis emphysema #103
      oxidative burst #103
      hla dr1 #103
      ros homeostasis #103
      drb10401 #103
      agalactosyl #103
      thelper cells #104
      arthritic disease #104
      mutation mice #104
      nonarthritic #104
      haplotypes histocompatibility #104
      f1 males #104
      skg mice #104
      mhcii #104
      synchrotron infrared #104
      male mice mice #104
      vivo macrophages #105
      type 22 #105
      fcγr #105
      development antibodies #105
      autoreactivity #105
      osteoclasts mice #105
      hybridoma cell #105
      dmaam #105
      273 #106
      disease dose #106
      arthritis hla #106
      primed cells #106
      proteoglycan loss #106
      limited cross #106
      tcell immunity #106
      cells synovial #107
      nzb mice #107
      c3h mice #107
      fpr #108
      littermates #108
      study tolerance #108
      development autoimmune disease #108
      reactive cell #109
      presentation cells #109
      structural polymorphism #109
      enthesophytes #109
      monoclonal igg #109
      type hypersensitivity #109
      autoantibodies autoantigens #109
      citrullinated proteins #109
      delayedtype hypersensitivity #109
      autoimmune encephalomyelitis #110
      carcinoma tumors #110
      cartilage #111
      streptococcal cell wall #111
      experimental female #111
      female hypersensitivity #111
      inbred dba microscopy #111
      toxic shock syndrome #111
      backcross #111
      dba 1j mice #111
      mog eae #111
      extensive literature search #112
      humoral autoimmunity #112
      alphabeta receptors antigen #112
      amide bond #112
      anti idiotypic antibodies #112
      presymptomatic individuals #112
      mice collageninduced arthritis #113
      db1 #113
      adjuvant properties #113
      tcra #113
      oligoclonality #113
      autoimmune c57bl mice #113
      trait loci #113
      restricted cell #113
      xid mice #113
      ifngammaproducing cells #114
      adjuvantinduced arthritis #114
      proinflammatory cytokine #115
      anti mcv #115
      mice disease #115
      drb10402 #115
      rats collagen #115
      autoantigens autoimmunity #115
      experimental epitopes #116
      lutz #116
      pathogenesis autoimmune diseases #116
      lymphocyte female #116
      glycopeptides #116
      susceptibility eae #116
      ccp patients #116
      glyco #116
      immunosorbents #116
      transgenic peptides receptors #116
      encephalomyelitis autoimmune #117
      tolerance induced #117
      congenic lines #117
      antibodies reactive #117
      fluorescence nf #117
      antiarthritic #117
      mice type #117
      psoriasiform dermatitis #118
      class expression #118
      α enolase #118
      rats immunized #118
      myelin oligodendrocyte #118
      pineal hormone #118
      samples individuals #118
      alpha1acid #118
      psa rheumatoid arthritis #119
      cd4 tcells #119
      radiological damage #119
      rheumatoid arthritis review #119
      response cells #119
      05m #119
      neutrophils nets #120
      protein mbp #120
      experimental animal models #121
      vivo animal models #121
      chondrocyte cultures #121
      pharmacological potential #122
      acpa negative #122
      transfer arthritis #122
      patients acpa #122
      t‐lymphocyte #122
      immune complex deposition #122
      treatment progesterone #122
      genes age #122
      transgenic neurons receptors #122
      type cytokines #123
      alphabeta cells #123
      cell monoclonal #123
      c5b #123
      nox2 activation #123
      symptoms associations #123
      cartilage surface #124
      tlr4 stimulation #124
      inbred mouse #124
      allelic variations #125
      general mechanisms #125
      disease mechanisms #125
      preimmunized #125
      helperinducer #125
      genetic rats #125
      cryogel #125
      blocking antigens #125
      oxidases neutrophils #125
      immunodominant peptide #125
      qtl genes #125
      cyclic polymorphism #126
      female immunization #126
      nonobese diabetic #126
      nzb nzw #126
      pnipaam #126
      atp8 #127
      animal enzyme #127
      microarray detection #127
      knockout murine #127
      absence cells #127
      dominant epitope #128
      chronic inflammatory disease #128
      anticitrullinated peptide #128
      lining layer #128
      deiminases #128
      rats patients #129
      multiple epitopes #129
      bxsb #129
      spleen rats #129
      cells eae #130
      oestradiol testosterone #130
      psd1 #130
      disease induced #130
      nos2 #130
      vivo absence #130
      epitope specific #131
      onset arthritis #131
      lipomannan #131
      pronociceptive #132
      disease cgd #132
      induction regulatory cells #132
      kgf #132
      intercross #132
      linomide #132
      mineral oils #132
      ggaa #133
      reduced severity #133
      leukosialin #133
      rat chromosome #133
      eae #134
      patients cytokines #134
      mice estrogen #134
      myocellular #134
      plasma synovial fluid #134
      species animals #134
      knockout receptors antigen #134
      accentuate #134
      interstitial collagens #134
      spinal glial #135
      igg immune complexes #135
      peptides cyclic #135
      immunizing #136
      macrophages dendritic #136
      intracellular reactive #136
      chronic autoimmune disease #136
      innate lymphocytes #137
      stimulated muscle #137
      immunopathological #137
      receptor upregulation #137
      ditiocarb #138
      mice deficient #138
      control development #139
      dmannitol #139
      immunomodulatory drug #139
      autoimmune mice #139
      tcrdelta #140
      oligoclonal expansion #141
      producing cell #141
      thermoresponsive polymer #141
      genetic factors development #142
      single subcutaneous injection #142
      interferon‐γ #142
      gamma lymphocyte #142
      rejection tolerance #142
      phadia #142
      smfish #142
      or113 #142
      tcell alphabeta receptors #143
      cell hybridoma #143
      class haplotypes #143
      phosphate isomerase #143
      mice beta #143
      rheumatoid arthritis #144
      synovial hyperplasia #144
      rat strains #144
      mhc haplotypes #144
      tnf production #145
      severe chronic #145
      tcr gamma delta #145
      lyme arthritis #145
      inbred buf rats #145
      treatment ici #145
      syngenic #145
      neonatal growth #146
      rats induced #146
      systemic challenge #147
      cellular heterogeneity #147
      ccp antibodies #147
      pregnancy levels #147
      function cells #147
      gammainterferon #147
      interestingly #148
      autoimmune disease #148
      α2i #148
      cell surface antigen #148
      phagocyte nadph oxidase #148
      redox regulation #148
      complex diseases #149
      human autoimmune diseases #149
      drb104 #150
      mhc binding #150
      larsen score #150
      receptor rats #151
      epicutaneously #151
      differential gene expression #151
      levels antibodies #151
      mice animals #151
      humans hybridomas #151
      alphabeta receptors #152
      arthritic animals #153
      pepsin #153
      mononuclear cells #153
      key player #153
      levels pregnancy #153
      expression class #154
      selfpeptides #154
      fcgammar #154
      critical event #154
      c4bbinding protein #154
      immune priming #154
      daf1 #154
      male rats rats #154
      joint inflammation #154
      infiltrating cells #155
      f1 mice #155
      autoantibodies autoimmune #155
      serum synovial fluid #155
      arthritis rheumatoid #155
      padi4 #155
      mace acs #155
      specificities #156
      suppressive role #156
      stabilin1 #156
      mhc region #156
      downstream signals #157
      adjuvanticity #157
      murine keratinocytes #157
      analysis structure #158
      parentals #158
      hypersensitivity reaction #158
      genetic diabetes mellitus #158
      animals autoimmunity #159
      consensus motif #159
      inbred c3h mice #159
      systemic mice mice #159
      arthritis infectious #159
      meaib #159
      specific autoimmunity #161
      benzylated #161
      gamma interferon #161
      day onset #161
      knockout severity #161
      factors anti #161
      nursed #161
      arthritis inflammation #162
      cd152 #162
      epitope #162
      binding collagen #162
      βarrestin recruitment #162
      rheumatoid autoantigens #162
      anti ccp #162
      psors1 #162
      onset disease #163
      mouse type #163
      laboratory rats #163
      chains humans #163
      striking similarities #164
      autoantibody responses #164
      genes qtl #164
      rats induction #164
      mrl #164
      endobetanacetylglucosaminidase #164
      progesterone effects #164
      agalactosyl igg #164
      cells macrophages #165
      animal humans immunity #165
      tolerance induction #166
      epitope alleles #166
      pathogenic pathways #166
      nonimmunized #166
      melatonin mice mice #166
      class mice #167
      tlymphocyte humans #167
      ag7 #167
      human autoimmunity #167
      nox2 #167
      seronegative #167
      phase disease #168
      cd1 #168
      genetic backgrounds #168
      mice cd4 cells #168
      oxazole #169
      acpa levels #169
      p12 #169
      denoted #169
      mirp #170
      inherited disorder #170
      joints male #170
      cryogels #170
      experimental animal #170
      lymph node cells #170
      pathogenesis arthritis #170
      oxazolone #171
      ros nitric oxide #171
      encephalomyelitis eae #171
      rheumatoid #172
      autoimmune eae #172
      rat placenta #172
      single nucleotide polymorphism #172
      autoimmunity cell #172
      lst1 #172
      peripheral lymphoid organs #172
      monoclonal autoantibodies #173
      inbred dba models #173
      sod3 #173
      presence autoantibodies #174
      nasal cartilage #174
      resistant rats #174
      class gene #174
      studies pain #174
      ifn signature #175
      maternal decidua #175
      mice mutation #175
      understanding pathogenesis #175
      mammalian crosses #176
      moab #176
      skin disease #176
      new mouse model #176
      strains molecular #176
      tryptophan catabolism #176
      secondary challenge #176
      lymphotoxinα #177
      ctla‐4 #178
      histocompatibility #178
      hladrb1 alleles #178
      mice role #179
      protein anti #179
      immunized #179
      nod genes #179
      alternative pathway complement #179
      dextran sulphate sodium #179
      epitopes female #180
      complex disease #180
      arthritis methods #180
      cgd patients #180
      alleles arthritis #181
      molecular adaptations #181
      genetic influence #181
      autoimmunity disease #181
      hormone melatonin #182
      arginine deiminases #182
      immunoglobulin mice mice #185
      multistep process #186
      rats reactive #186
      antigen processing presentation #186
      cells lymph nodes #186
      b10 #187
      tcell recognition #187
      drb1 chains #187
      dba #187
      substrains #188
      chondritis #188
      molecular peptide #188
      cells disease #189
      mtec #189
      synovial membranes #190
      positionally #190
      inflamed joint #190
      hnrnpa2b1 #190
      oligodendrocyte glycoprotein #191
      cross‐reactivity #192
      ly1 #192
      autoantibody profiles #192
      passive mice mice #193
      fmlf #193
      proteins myelin #194
      glycoprotein peptide #194
      cyclic predictive #194
      mice mutant #195
      chapter 16 #195
      perpetuate #195
      mhv #195
      mhc class expression #196
      oophorectomized #196
      lewis rat #196
      tcell response #196
      myelin glycoprotein #196
      acutephase response #197
      pannus #197
      multiplex assay #197
      evidence development #197
      igmrf #198
      swedish patients #198
      early appearance #198
      genetic links #198
      rat genome #199
      dr4 antigen #199
      interleukin17 #199
      cell collagen #200
      citrullinated peptide #200
      hla association #200
      pathogenesis autoimmune #201
      myelin proteins myelin #202
      myelin proteolipid protein #202
      dendritic cells macrophages #202
      instigation #202
      acpa status #202
      mice cells #203
      complete elimination #203
      2 complex #204
      class molecules #204
      immunization immunoglobulin #204
      spleen staining #204
      nonparametric tlymphocytes #205
      ides #205
      macrophages mice #205
      suppresses #205
      native collagen #205
      dth response #205
      betaestradiol #206
      wild rats #206
      defb4 #206
      insulitis diabetes #207
      noxs #207
      desmoglein 3 #207
      alternative complement pathway #207
      interleukin4 mice mice #207
      parental strains #207
      induced upregulation #207
      mice peptide #207
      intranasal challenge #207
      severity disease #208
      highest probability #208
      immunization mice #208
      naive mice #208
      antigen presenting #208
      vivo patients #208
      immunoglobulin vh #209
      cotwins #209
      disease rheumatoid #209
      highfatdiet #210
      valuable tools #210
      vav1 #210
      specific antibodies #210
      susceptible strains #210
      citrullinated vimentin #210
      natural antibodies #211
      purified protein derivative #211
      diseases genetic #211
      hla dr4 #211
      glucose6 phosphate #211
      cells immobilized #212
      association rheumatoid arthritis #212
      large numbers #212
      psoriasiform #213
      mice injected #213
      antibody binding #213
      tsst1 #214
      central tolerance #215
      inbred rat #215
      mhc class antigens #215
      antigen induced #215
      triethylsilane #215
      cytofluorometric #215
      training hiit #216
      dissect #216
      lower level #216
      lentiviral vector #217
      induced autoimmune #217
      cd23 #217
      resistant strain #217
      rats immunization #217
      inflammatory infiltrates #217
      joints mice #217
      treatment onset #218
      antigen tcell #218
      k8 #219
      autoimmunity #219
      fcrγ #219
      granuloma formation #219
      peptide antibodies #219
      cells autoimmune #220
      hyl #220
      bone erosions #220
      peptidylarginine deiminases #220
      redox signaling #221
      rheumatoid factor #221
      pinealectomy #221
      agouti rats #221
      targeted deletion #221
      fine specificity #221
      cyclosporin treatment #221
      cells dendritic #221
      cartilage damage #222
      cybb #222
      thymectomized #222
      wkymvm #222
      monoclonal antigens differentiation #222
      igg2a #223
      carbamylated #223
      multiplex #223
      experimental autoimmune neuritis #223
      inflammation vivo #224
      expressing #224
      clinical scoring #225
      interleukin‐10 #225
      lew #225
      cells antigen #225
      established disease #225
      pathogenic antibodies #226
      disease locus #226
      macrophagelike cells #227
      j1 #227
      delayed type hypersensitivity #228
      arthritis objective #228
      presenting cells #228
      cell selection #229
      presence anti #229
      eae rats #230
      site inflammation #230
      human rheumatoid #231
      ls1 #231
      monoclonal immunohistochemistry #232
      reactive oxygen #232
      synovial joints #233
      role eosinophils #233
      ameliorated #233
      lack expression #233
      production ros #233
      centimorgan #234
      lower numbers #234
      mhc gene #235
      staphylococcal infection #235
      chronic psychosocial stress #235
      chromosome 14 #235
      immune complex #236
      specificity animals #236
      control strain #237
      pathological mechanisms #237
      progression arthritis #238
      autoimmune chronic #238
      trait locus #239
      c5 #239
      inbred dba tlymphocytes #240
      study plasma #241
      strong influence #242
      joint pain #242
      monoclonal antigen #243
      class genetic #243
      multicomponent #243
      positive anti #243
      hla drb1 #243
      protected #243
      cutaneous infection #244
      treatment autoimmune #244
      common denominator #244
      inflammation cartilage #244
      estrus cycle #244
      crosses #244
      binding antibodies #245
      rt1l #246
      allelic differences #246
      development emphysema #246
      new model #247
      inbred strain #247
      antibodies anti #247
      antibody response #247
      florescence #247
      normal cartilage #247
      activity assays #248
      efficient expression #248
      oxygen species #249
      induced chronic #249
      node cells #250
      fragments rats #250
      arthritic joints #250
      inflammation score #250
      picryl #250
      mouse rat #250
      treatment rats #251
      hyperinflammation #251
      conditional knockout mice #251
      develops #251
      nadph oxidase #251
      mice lymphocytes #252
      dark agouti #252
      response disease #252
      role model #252
      mice lack #252
      cartilage matrix #254
      dinitrofluorobenzene #254
      class mhc #254
      onset clinical #254
      proteins glycoproteins #254
      lpr mice #254
      lacking #254
      autoimmune response #255
      inbred c3h #255
      inflammatory disorder #256
      postmenopausal bone #256
      anti arthritic #256
      specific neutralizing #256
      specific subgroups #256
      disease cell #257
      additive interaction #258
      class mhc molecules #259
      relationship immunologic #260
      mir144 #260
      chronic granulomatous #260
      lymphocytes helper #261
      autoimmune neuritis #261
      secondary osteoporosis #261
      mediated suppression #261
      denatured #261
      mice expressing #261
      immunologic animals #262
      selfantigen #263
      tolerance mice #265
      pregnancy mice #265
      mouse strain #265
      primary immunization #265
      crossreactive #265
      genetic techniques #265
      cysteine proteases #267
      vim2 #267
      rats animals #267
      antigen specific #267
      posttranslational modifications #268
      lentiviral gene #268
      xid #268
      mann whitney #269
      pathogenic roles #269
      oxpl #270
      complement c5 #270
      selfantigens #271
      monosodium urate crystals #271
      melatonin effects #271
      castrated #271
      experimental model #273
      amino acid transporters #273
      lewis rats #274
      nasally #275
      inhibitory peptide #275
      hdac1 #275
      tcells #275
      synovial lining #275
      fcgr3b #276
      macrophages dendritic cells #276
      rheumatoid arthritis association #277
      deiminase type #277
      producing cells #277
      viral female hepatitis #277
      metabolic properties #278
      recognize #278
      interferongamma #279
      gp70 #279
      colon length #279
      induced tolerance #280
      dinucleotide phosphate #280
      neonatal mice #281
      immunological receptors antigen #281
      passive transfer #281
      inflammatory conditions #281
      recipient mice #281
      hemiacetal #282
      inbred nod #283
      factor production #283
      isoflavone genistein #283
      igg2b #283
      disease susceptibility #283
      helper inducer #284
      increased serum levels #284
      aire #284
      severe colitis #284
      theilovirus #285
      endophilin #285
      publication animals antibodies #285
      aureus strain #285
      idiotope #285
      complete protection #285
      maintained #285
      emulsified #286
      hla dr2 #287
      melatonin mice #288
      melatonin release #288
      tlr9 mice #288
      myelin basic protein #288
      antibody production #288
      cells autoimmunity #289
      mice immunized #289
      synovial cells #291
      disease cells #291
      ctla4 expression #291
      autoimmune mechanisms #292
      rheumatic conditions #292
      induced ros #293
      cytokines disease #293
      increased copy #293
      collagen receptors #293
      unique model #294
      mouse genes #294
      c57bl 6 mice #295
      antigen processing #295
      gastric parietal #295
      c3h #295
      immunological receptors #296
      nerve conduction #296
      tissue‐specific #296
      6week #296
      dnfb #297
      phosphopyruvate #297
      murine dendritic cells #297
      helical peptides #297
      gene selection #298
      cd19 cells #298
      vivo imaging #298
      ppad #298
      citrullination #299
      solidphase synthesis #299
      transplantation antigens #299
      tcr beta #300
      neutrophil extracellular traps #301
      posttranslational rats #301
      peptide antibody #302
      extraembryonic tissues #302
      alphabeta #302
      draining lymph #302
      1 interferon #303
      pathogeneses #303
      animals antibodies #303
      strains mice #303
      epidemiological investigation #303
      igg glycosylation #304
      cgd #304
      conditioned disease models #304
      autoimmune diseases #304
      immunological function #305
      cartilage development #305
      cells tcr #305
      mutant strains mice #305
      murine colitis #306
      hcdr3 #306
      αgalcer #306
      immunological studies #306
      gammaifn #306
      class histocompatibility #307
      inpp4b #307
      immunisation #307
      basal metabolic rate #308
      chromosome 10 #309
      basal metabolic #309
      articular cattle cells #310
      arthritis study #310
      perpetuation #311
      multiple sclerosis eae #311
      alleles animals #312
      synthetic peptide #312
      inflamed joints #312
      disease symptoms #312
      c3bi #313
      exuberant #313
      epitopes #313
      activatory #314
      induced colitis #314
      intradermally #315
      mice genes #315
      r620w #315
      trypanosoma brucei brucei #316
      onset rheumatoid #318
      classical risk factors #318
      genetic interactions #319
      galactosyl #319
      tubule cells #319
      deiminase #320
      spleen bone marrow #320
      mice subjected #320
      genomewide linkage analysis #320
      cells specific #323
      il21r #323
      expressing human #324
      ccp1 #324
      daf2 #324
      impact disease #324
      expression cells #325
      rat gene #325
      specific cell #325
      surprisingly #326
      mgps #327
      resembles #327
      allelic variant #328
      c57bl mice #328
      publication adjuvants #329
      constant light #329
      immunoenzyme #329
      complex genes #330
      early arthritis #331
      rheumatoid synovial #332
      glycoprotein mog #332
      fcgammariia #332
      nucleotide polymorphism #332
      mouse hepatitis virus #333
      anticcp #333
      35ssulfate #334
      joint tissues #335
      susceptibility genes #335
      mrl lpr mice #335
      autoimmune inflammation #336
      cell response #338
      epitope specificity #340
      delayed onset #340
      cells spleen #340
      adjuvants immunologic #341
      erosive #341
      ros oxygen species #341
      activation macrophages #341
      rat #341
      specific autoimmune #342
      6weeks #342
      incident cardiovascular events #342
      animal enzyme inhibitors #342
      rapid spread #343
      sequence animals #343
      drb1 alleles #343
      rats injection #343
      diabetic mouse #343
      monoclonals #344
      182780 #344
      favor #345
      acpa positivity #345
      energetic costs #346
      intraperitoneal injection #347
      pemphigus vulgaris pv #348
      complement activity #349
      reduced capacity #349
      neuritis #349
      igg autoantibodies #350
      phenotype rats #351
      thymic selection #352
      methylcholanthrene #352
      anti cyclic #353
      c3h hej #353
      mice induction #353
      immunoregulation #353
      mice cd4 #354
      autoantigens autoimmune #354
      arthritis synovial #354
      splenic macrophages #355
      dsg3 #357
      adjuvant activity #358
      cells autoantibodies #358
      tbetarii #358
      injected #359
      enos #359
      neuritogenic #359
      tcrbeta #360
      pvg #361
      tlr3 #361
      freund #361
      murine lupus #362
      hla transgenic #362
      identification genes #363
      determines #363
      allergic encephalomyelitis #363
      mouse chromosome #363
      generation ros #363
      hladr4 #364
      recognized #364
      cells anti #364
      sex chromosomes #366
      european journal #366
      immune deviation #366
      glycoproteins mice #366
      psychosocial stress #367
      antiidiotypic antibodies #367
      autoimmune responses #368
      loci #368
      ncf2 #368
      toxic shock #368
      100 micrograms #368
      affinity ligand #368
      nasal administration #369
      histocompatibility antigens #369
      pentameric #369
      increased production #370
      immune pathogenesis #370
      serum transfer #371
      regulate #371
      clinical onset #371
      role mif #372
      newborn antibodies #372
      alternative activation #373
      rheumatoid cell #375
      autoantigens #375
      acutephase proteins #376
      undifferentiated arthritis #376
      glucose6 #377
      gia #379
      reparixin #380
      mouse monoclonal antibody #381
      induced lupus #381
      oxidase deficiency #381
      fia #382
      fragments immunoglobulin #382
      granulomatous #383
      granulomatous disease #384
      c1a #384
      naive rats #384
      specific loci #384
      postmenopausal bone loss #385
      shock syndrome #385
      cell specificity #386
      pc4 #386
      filaggrin #387
      backcrosses #387
      ptpn22 gene #387
      antioxid #387
      inbred nod receptors #388
      phase response #388
      downregulating #389
      deficient #390
      ovulation rate #390
      greater 50 #390
      peptidylarginine #391
      anaphylatoxin c5a #391
      radiological progression #391
      finetune #392
      rf1 #394
      il4 il10 #394
      ameliorating #395
      induced metabolic #397
      autoantibody levels #397
      draining #397
      juvenile chronic arthritis #398
      regulation animals #399
      protein myelin #399
      immunized mice #399
      inflammatory reactions #400
      reactive oxygen species #400
      antibody formation #401
      genes cells #401
      inflammation demyelination #403
      immunopeptidome #403
      biacore #403
      beta chain #404
      fcγriib #404
      basic protein #405
      experimental #405
      n31 #407
      rheumatoid case #407
      effects models #407
      pam3csk4 #408
      major locus #409
      immunogenetics #409
      3hproline #410
      diabetes loci #410
      intracellular processing #410
      cell phenotypes #412
      hladrb1 #412
      cd43 #412
      susceptibility loci #413
      titres #413
      reproductive performance #414
      characteristic feature #414
      cultured collagen #415
      igk #415
      female mice #416
      levels autoantibodies #416
      spontaneous mutation #417
      lupus mice #417
      synovial inflammation #417
      genetically modified mice #418
      class hdacs #419
      molecular interactions #419
      wtccc #419
      induced pain #419
      hiit #420
      ameliorate #420
      tcell #421
      dr4 #422
      lower affinity #422
      lipidomic #423
      restricted #424
      subsets animals #424
      hyaline cartilage #425
      congenic strain #426
      regulatory animals #426
      inflammatory cells #426
      carbohydrate moiety #429
      epitopes humans #430
      nonimmunogenic #430
      postimmunization #430
      nod mouse #430
      immunoregulatory #431
      il10 mice #433
      patients healthy individuals #433
      cells antibodies #434
      spontaneous autoimmune #435
      factor 5 #435
      cells beta #436
      reactivities #436
      crystallizable #437
      chromosomes chromosome #437
      decalcified #437
      mass spectrometric analysis #437
      helperinducer tlymphocytes #438
      mice effects #438
      immunised #438
      specific antigens #438
      joint swelling #439
      cells #439
      nod #440
      wildtype mice #440
      vitro techniques leukocytes #441
      normal rats rats #441
      effector functions #441
      female immunoglobulin #441
      mice activation #442
      complete adjuvant #442
      patients population #442
      mhc class molecules #443
      methylβcyclodextrin #443
      tlr2 expression #444
      myelin basic #444
      systemic mice #445
      mouse models #445
      genomewide scan #445
      mice humans #445
      skeletal muscle function #445
      ros production #447
      inbred strains receptors #448
      induced mice #448
      pain model #448
      control mice #448
      synovial tissue #449
      tcell responses #449
      complement factor #449
      innate adaptive #450
      igg anti #451
      apcs #451
      hybridoma cells #452
      reduced production #452
      heterologous #452
      differs #454
      cells chronic #456
      lglutamine #456
      inbred c57bl tlymphocytes #457
      raloxifene #457
      rheumatoid cells #459
      eae cns #459
      resembling #459
      lung macrophages #459
      priming #459
      antibodies monoclonal #460
      256 #462
      neutrophil functions #462
      autoantigen #462
      gilt #463
      fab fragments #464
      autoantibody production #465
      salivary glands #466
      receptor tcr #466
      cells lymph #467
      titers #469
      earlier onset #469
      antibody mediated #474
      anticyclic citrullinated peptide #474
      disease mice #474
      arthritic rats #474
      cartilage cells #475
      human autoimmune #476
      mice exhibited #477
      cluster genes #477
      therapeutic vaccination #478
      mediated inflammation #478
      female hla #479
      apoptosis arthritis #479
      laboratory rat #479
      quantitative trait loci #480
      aggravated #480
      deacetylase 1 #480
      anti idiotypic #482
      polymorphonuclear cells #482
      immune reactions #484
      immunologists #485
      immunoglobulin male #486
      controlling #487
      tcralpha #487
      jca #487
      oxyntic #487
      invariant natural #488
      specific immune #488
      insulitis #488
      gland animals #489
      normal mice #490
      cytoplasmic calcium #494
      nacetylglucosaminidase #495
      conclude #496
      early rheumatoid #496
      reactive nitrogen #496
      h2b #496
      gammadelta cells #496
      small effects #498
      mbp #498
      receptor 9 #499
      biologicals #500
      immunoenzyme techniques #503
      autoreactive cd4 #503
      nadph #503
      pathogenic #506
      immunofluorescence analysis #507
      chondrocytes collagen #507
      persistent pain #508
      mineral oil #508
      isopropyl #508
      mab mabs #508
      gingipain #509
      immunization passive #509
      orosomucoid #509
      mice knockout mice #510
      mhc class #510
      c3h hej mice #511
      systemic spread #511
      deficient mice #511
      differential gene #511
      812 #511
      blymphocytes #512
      mrp8 #515
      hydroxyquinolines #517
      behavioral alterations #517
      u1 #518
      antibody complex #518
      chronic granulomatous disease #519
      suggestive linkage #519
      inflammation #519
      tcr recognition #520
      modified form #521
      dextran sulfate sodium #522
      pcorr #522
      ttg #522
      data peptide #523
      inflammation role #523
      litter size #524
      encephalitogenic #524
      p47phox #524
      neutrophil granulocytes #525
      mechanical hypersensitivity #526
      tconv #526
      mnc #526
      disease acute #527
      maternal antibodies #527
      spleen cells #527
      larsen #528
      tolonium #528
      primed #528
      vaccinates #528
      displayed #529
      tolllike receptor tlr4 #529
      ifa #529
      rat rats #529
      cell antibodies #530
      isac #530
      pathogenesis sle #530
      antigen presentation #530
      autoantibody #530
      ratg #531
      epistatic #532
      bred #532
      complex role #533
      lyt2 #533
      posttranslational receptors #534
      resorptions #536
      spleen lymphocytes #536
      translational modification #536
      urokinase #537
      synovial #537
      cells inflammatory #538
      experimental rats #538
      animals #538
      suppressive #540
      joints #540
      antigen recognition #540
      fibroblast synoviocytes #540
      membrane attack complex #541
      rheumatoid humans #543
      specific autoantibodies #544
      protein tyrosine phosphatase #545
      regulating #545
      hypomorphic #546
      shortcut #547
      animal gene #547
      tlymphocytes #547
      immunohistochemical methods #548
      formyl peptide receptors #548
      entheses #548
      mog #550
      immunoglobulin fab #552
      mixed lymphocyte reaction #553
      nox activity #554
      breeder #555
      beta animals #557
      cell epitopes #557
      stronger association #557
      cells control #558
      early onset #559
      healthy mice #560
      elispot assay #561
      transgenic molecular #562
      ptdins3p #563
      inbred strains #563
      negative selection #563
      neutrophil depletion #564
      therapeutic treatment #565
      deeper layers #565
      immunoglobulin heavy chains #566
      darkness #566
      earlier #566
      target tissue #566
      crucial #567
      outbred #568
      disease loci #568
      interferon signature #568
      cells pathogenesis #569
      mycobacteria #569
      neutrophilia #569
      concomitantly #570
      mice compared #571
      transgenic mouse models #572
      btla #572
      keratin8 #573
      col2 #574
      pepstatins #576
      presenting #576
      estrogen treatment #577
      terpenes #577
      keratinocyte growth factor #578
      prolactin prl #578
      ptm #579
      sera patients #579
      triple helix #580
      methotrexate mice #581
      f1 hybrids #581
      hybridoma #583
      inflammatory joint #583
      production ifngamma #583
      lymphocyte antigens #584
      exaggerated #584
      time onset #584
      antibody reactions #585
      traps nets #590
      environmental triggers #591
      antigen antibody #591
      immunological tolerance #592
      lxrα #592
      oligoclonal #592
      transgenic models #593
      noncollagenous #593
      macrophages #594
      adaptive immunity #594
      autoimmune disorders #594
      multiplexing #595
      th1 cytokines #595
      clonal expansion #595
      xanthine oxidoreductase #596
      cells study #599
      tcell activation #599
      develop #600
      augmented #602
      n85 #602
      spite #602
      th2 cytokines #602
      common diseases #603
      mouse monoclonal #603
      pemphigus vulgaris #603
      phagosomal #604
      cells male #604
      cells involved #604
      mice inbred #606
      animal rats #606
      oxa #606
      class humans #607
      frozen sections #608
      genotype hla #608
      spleen animals #609
      inefficiently #610
      regulatory role #610
      naive #611
      production ifn #611
      positive individuals #612
      quantitative trait locus #615
      mutant strains receptors #616
      acetophenones #616
      alpha chains #616
      autoantibodies #616
      exponential phase #616
      class antigens #616
      idiotypic #616
      th1 type #616
      oral immunization #617
      nonobese #617
      beta type #618
      day mice #619
      wistar restraint #620
      promiscuous #620
      receptor 3 #621
      consequent #621
      inflammatory role #621
      nicotinamide adenine #622
      fluorine18 #624
      receptors antigen #624
      loci identified #625
      chronic stage #625
      cytoplasmic ca2 #628
      animal mice #628
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      human chondrocytes #2110
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      immune functions #2126
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      inflammatory #2288
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      inflammatory mechanisms #2321
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      th1 response #2852
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      polymorphonuclear leukocytes #2856
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      dependent cell #2859
      treg cell #2859
      antibodies antinuclear #2864
      polymorphonuclear #2864
      interleukin receptors #2864
      splenocytes #2865
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      atp synthase #2909
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      ifn response #2985
      cepacia #2988
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      anthrax #3019
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      wild type mice #3026
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      vdr #3031
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      lung inflammation #3033
      macrophage migration #3036
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      t‐cell #3039
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      interleukin23 #3061
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      staphylococcus #3114
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      logarithm #3146
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      cba #3164
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      cell specific #3185
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      adult mice #3193
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      phagosomes #3212
      nitroarginine #3212
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      cells animals #3224
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      bacterial antibodies #3254
      backbone #3257
      nonalcoholic steatohepatitis nash #3260
      female gonadal #3263
      treated animals #3264
      acrylic #3265
      chronic inflammatory #3267
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      inflammation interferon #3278
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      sch #3280
      arthralgia #3283
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      gonadal steroid #3284
      normal rats #3287
      abundantly #3289
      igg1 #3298
      models genetic #3298
      immunoglobulin heavy #3303
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      adaptations #3309
      proteins mice #3309
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      blastocyst #3315
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      diseases autoimmune #3321
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      beta receptors #3325
      mice protein #3327
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      suppression #3338
      regional lymph nodes #3341
      macromolecular #3343
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      influenced #3355
      trypanosoma #3358
      akr #3371
      vitamin d3 #3373
      editor #3377
      antinuclear antibodies #3382
      sle #3384
      genetic polymorphisms #3385
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      levels inflammatory #3395
      macroporous #3395
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      mount #3397
      tubercle #3402
      somatic mutations #3406
      receptors transforming #3410
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      haptens #3413
      positions #3418
      nk cells #3419
      erythematosus systemic #3419
      reacts #3421
      neutrophil activation #3421
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      reply #3432
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      alleles #3440
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      4 months #3444
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      superoxide production #3446
      protein tyrosine #3447
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      h5n1 #3470
      flow cytometry #3476
      modifying #3477
      multimers #3491
      inflammatory mediators #3491
      proteoglycan #3496
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      ly #3501
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      neutrophilic #3510
      pathobiology #3511
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      specific cd4 #3519
      globulins #3526
      267 #3528
      deoxyguanosine #3528
      germline #3529
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      lacrimal #3534
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      transglutaminases #3535
      radiolabelled #3539
      regulatory cells tregs #3540
      cyclosporins #3540
      mbq #3541
      dominantly #3548
      histological examination #3554
      investigate #3559
      infections staphylococcus #3561
      mast cells #3563
      cultured disease models #3568
      socs1 #3570
      humans interferon #3571
      histological #3574
      homogenate #3576
      interesting #3580
      gamma #3580
      negative patients #3583
      artificially #3584
      role development #3585
      cytolytic #3589
      hindlimb #3590
      il33 #3593
      compared wild #3597
      triggered #3597
      usage #3601
      immunohistochemical staining #3608
      upregulation #3612
      previous findings #3617
      intranasal #3619
      tcr #3622
      cleave #3624
      potential roles #3624
      genetic association #3629
      rp #3633
      attenuate #3633
      mapping chromosomes #3634
      genetic #3637
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      adhere #3638
      today #3645
      cultured culture media #3651
      allele #3655
      gene deletion #3657
      enhances #3657
      cd4 positive #3659
      exerts #3663
      tolllike receptor #3665
      clinical severity #3665
      luminol #3667
      95 association #3671
      cd44 #3678
      il23 #3690
      tgf beta #3691
      female genes #3694
      fibronectins #3697
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      Prominent publications by Rikard Holmdahl

      KOL-Index: 15284

      The purpose of the study was to map the dominant T cell epitope of the CB11 sequence of CII in RTlu haplotype rats and to determine if, when used as a synthetic peptide, it would induce tolerance to protect against CIA. A dominant epitope corresponding to residues 184-198 included in the sequence of the CB11 fragment of bovine CII was identified in proliferation assay using peptides in an epitope scanning system using synthetic peptides of 15 amino acids, overlapping by 12 amino acids. ...

      Bekannt für Mucosal Tolerance | Synthetic Peptide | Cell Epitope | Cia Cii | Collagen‐induced Arthritis
      KOL-Index: 14658

      An antibody response to defined epitopes located on the triple helical portion of type II collagen (CII) is associated with the development of collagen-induced arthritis (CIA) and rheumatoid arthritis (RA). Monoclonal antibodies to epitopes associated with arthritis, but not antibodies specific for epitopes not associated with arthritis, induce arthritis in mice, the so-called collagen antibody induced arthritis (CAIA) model. We have selected monoclonal IgG antibodies specific for four ...

      Bekannt für Collagen Antibody | Induced Arthritis | Monoclonal Antibodies | Mice Inbred | Specific Epitopes
      KOL-Index: 13984

      The Aq major histocompatibility complex (MHC) class II molecule is associated with susceptibility to murine collagen-induced arthritis (CIA), whereas the closely related H-2Ap molecule is not. To understand the molecular basis for this difference, we have analyzed the ability of H-2Aq and H-2Ap molecules (referred to as Aq and Ap) to bind and present collagen type II (CII)-derived glycosylated and non-glycosylated peptides. T cell clones specific for the immunodominant CII 256-270 ...

      Bekannt für Collagen‐induced Arthritis | Transgenic Models | Aq Molecule | Structural Basis | C3h Mice
      KOL-Index: 13727

      BACKGROUND: Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis (RA), and associate with HLA-DRB1 shared epitope (SE) alleles.

      OBJECTIVE: To investigate reactivities of anti-CCP to various citrullinated proteins/peptides, which represent potential autoantigens in RA, and to examine the relationship between such antibodies, and their association with genetic variants within HLA-DRB1 SE alleles.

      METHODS: Serum samples from 291 ...

      Bekannt für Citrullinated Antigens | Rheumatoid Arthritis | Drb1 Alleles | Ccp Patients | Antibody Reactivities
      KOL-Index: 13726

      Type II collagen-induced arthritis (CIA) in mice is an autoimmune experimental model for rheumatoid arthritis. Susceptibility to CIA is associated with certain major histocompatibility complex class II haplotypes. The two very closely related haplotypes H-2q and H-2p differ in susceptibility to CIA. Only mice of H-2q (DBA/1, B10G strains) but not mice of H-2p-expressing strains (like strain B10P) develop CIA and an autoimmune response to type II collagen (CII) after immunization with ...

      Bekannt für Mice Cia | Beta Chain | Rheumatoid Arthritis | H2q Haplotype | Type Collagen Cii
      KOL-Index: 13513

      INTRODUCTION: It has previously been shown that an increased number of antibodies against citrullinated peptides/proteins (ACPA) predate the onset of rheumatoid arthritis (RA). Over time antibody positivity expands, involving more specific responses when approaching the onset of symptoms. We investigated the impact of human leukocyte antigen-shared epitope (HLA-SE) alleles and smoking on the development of ACPA, as well as in combination with ACPA during the state of quiescent ...

      Bekannt für Citrullinated Peptides | Onset Symptoms | Development Rheumatoid Arthritis | Combination Acpa | Hlase Smoking
      KOL-Index: 13230

      OBJECTIVE: High titers of specific anti-citrullinated protein antibodies (ACPAs) are frequently present in the serum of rheumatoid arthritis (RA) patients, but their presence in synovial fluid is less well characterized. The purpose of this study was to compare the levels of antibody to 4 well-defined citrullinated candidate RA autoantigens in serum and synovial fluid and to determine whether antibodies to one citrullinated antigen are dominant over another. Furthermore, we studied their ...

      Bekannt für Citrullinated Antigens | Synovial Fluid | Rheumatoid Arthritis Patients | Type Collagen | Antibodies Acpas
      KOL-Index: 12913

      INTRODUCTION: Toll-like receptors (TLRs) are involved in both innate and adaptive immune responses and are likely to play a complex role in the pathogenesis of human rheumatoid arthritis (RA) and experimental arthritis. The objective of this study was to identify the key TLR in pristane-induced arthritis (PIA), a rat model for RA, and to clarify its roles in the initiation and maintenance of arthritis.

      METHODS: Arthritis in DA rats was induced by pristane and the severity was evaluated ...

      Bekannt für Induced Arthritis | Tlr3 Expression | Rats Pristane | Receptor 3 | Inbred Strains Severity
      KOL-Index: 12776

      Multiple sclerosis (MS) is a complex chronic neurologic disease with a suspected autoimmune pathogenesis1,2. Although there is evidence that the development of MS is determined by both environmental influences and genes, these factors are largely undefined3,4, except for major histocompatibility (MHC) genes. Linkage analyses and association studies have shown that susceptibility to MS is associated with genes in the human histocompatibility leukocyte antigens (HLA) class II region, but ...

      Bekannt für Multiple Sclerosis | Transgenic Mice | Hla Dr2 | Humanized Model | Spontaneous Disease
      KOL-Index: 12721

      Polymorphism of the major histocompatibility complex (MHC) influences susceptibility to experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (MBP) in rats. Current concepts relate such influences to the capacity of class II molecules to present relevant peptides to autoreactive T cells. We have here analyzed the MHC influence on the immune response and the development of EAE after immunization with the immunodominant peptide MBP-63-88. Analysis of MHC-congenic ...

      Bekannt für Myelin Basic Protein | Experimental Autoimmune | Major Histocompatibility | Rats Eae | Immune Response
      KOL-Index: 12691

      OBJECTIVE: The presence of antibodies against cyclic citrullinated peptides has been demonstrated to precede the onset of symptoms of rheumatoid arthritis (RA) by several years. The aim of this study was to analyze antibodies against 10 citrullinated autoantigen-derived peptides for reactivity before the onset of RA symptoms.

      METHODS: A case-control study was conducted within the Medical Biobank of Northern Sweden. The study was performed in 409 individuals, 386 of whom donated 717 blood ...

      Bekannt für Citrullinated Peptides | Rheumatoid Arthritis | Onset Symptoms | Antibodies Cep1 | Type Collagen
      KOL-Index: 12510

      Antibodies against type II collagen (anti-CII) are arthritogenic and have a crucial role in the initiation of collagen-induced arthritis. Here, we have determined the dependence of T and B cells in collagen-antibody-induced arthritis (CAIA) during different phases of arthritis. Mice deficient for B and/or T cells were susceptible to the CAIA, showing that the antibodies induce arthritis even in the absence of an adaptive immune system. To determine whether CII-reactive T cells could have ...

      Bekannt für Collagen Type | Arthritis Mice | Antigen Tcell | Antibodies Cii | Adaptive Immune
      KOL-Index: 12427

      The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren's syndrome. To investigate whether NOD genes also promote autoimmune-mediated arthritis we established a NOD strain with an MHC class II fragment containing the A(q) class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contrast to other A(q) expressing strains such as B10.Q and DBA/1. To determine the major ...

      Bekannt für Genetic Control | Complement Factor | Induced Arthritis | Locus Chromosome | Mice Inbred

      Schlüsselpersonen für Rheumatoid Arthritis

      Top -Kols der Welt
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      Rikard Holmdahl:Expertenwirkung

      Konzepte für welcheRikard Holmdahlhat direkten Einfluss:Rheumatoid arthritis,  Induced arthritis,  Experimental arthritis,  Collagen type,  Type collagen,  Animal models,  Reactive oxygen species,  Autoimmune diseases.

      Rikard Holmdahl:KOL -Auswirkungen

      Konzepte im Zusammenhang mit der Arbeit anderer Autoren, für diefor which Rikard Holmdahl hat Einfluss:Rheumatoid arthritis,  Multiple sclerosis,  Autoimmune diseases,  Oxidative stress,  Animal models,  Reactive oxygen species,  Nadph oxidase.


       

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      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China | Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku,

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