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    • Rikard Holmdahl

      Rikard Holmdahl

      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China | Medical ...

       

       

      के लिए फिर से शुरू Rikard Holmdahl

      Year
      2022

      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

      Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku, Finland

      2021

      The Second Affiliated Hospital of Xi’an Jiaotong University (Xibei Hospital), Xi’an, China

      Department Medical Biochemistry and Biophysics, Division Medical Inflammation Research, Karolinska Institute, 171 77 Stockholm, Sweden;, (M.A.);, (X.C.);, (B.X.);, (G.F.L.);, (M.Y.B.);, (Y.H.);, (L.B.)

      Division of Medical Inflammation Research, Dept. of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden

      2020

      Dept. of Medical Inflammation Research, Section of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm

      Section for Medical Inflammation Research, BMCI11, Lund University, Lund, Sweden

      National & Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital, Xi'an Jiaotong University, 710004 Xi’an, China

      Karolinska Institutet

      2019

      Section for Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Solnavägen 9, 171 65, Solna, Sweden

      Center for Medical Inflammation Research, Southern Medical University, Guangzhou, China

      R. Holmdahl and C.I. Svensson contributed equally to this paper.

      2018

      School of Pharmaceutical Science, Southern Medical University, Guangzhou, China

      Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm 17177, Sweden. Electronic address:

      Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

      Medicity Research Laboratory, University of Turku, Turku, Finland

      2017

      Karolinska Institutet Division of Medical Inflammation Research Stockholm Sweden

      Center for Medical Immunopharmacology Research, Southern Medical University, 510515 Guangzhou, China.

      Medicity Research Laboratory, University of Turku, Turku, Finland, .

       

       

      Rikard Holmdahl: आँकड़ों को प्रभावित करें

      उन अवधारणाओं का नमूना जिसके लिए Rikard Holmdahl दुनिया के शीर्ष विशेषज्ञों में से एक है।
      Concept World rank
      hiit nox2 activity #1
      cb11 fragment #1
      transient joint inflammation #1
      respiratory burst severity #1
      insulitis strains #1
      igg2a vivo #1
      regulates severity #1
      lew1w rt1u #1
      nonglycosylated peptide #1
      m1j #1
      chromosome arthritis severity #1
      ability gut protection #1
      ftirm ciic1 #1
      obs electrophoresis #1
      transgenic nadph oxidase #1
      ll37 rcramp #1
      cia collagen #1
      antibody responses cii #1
      tolerance arthritis protection #1
      p47phox ncf1 #1
      autoimmune diseases identification #1
      oestrogen lupus disease #1
      experimental chromosomes #1
      thps cii #1
      immunologic animals arthritis #1
      presence sex hormones #1
      psa mip #1
      hyaluronanreceptor #1
      cia reduction #1
      rheumatoid arthritis autoimmunity #1
      p47phoxv232 #1
      h2w17 #1
      cartilage damage vivo #1
      experimental collagen type #1
      downregulating oestradiol #1
      ul1 ciif4 #1
      susceptible strain cross #1
      inflammatory arthritis assessment #1
      arthritis experimental #1
      plasminogendeficient mice arthritis #1
      tolerance collagen #1
      injection adjuvant oils #1
      mannaninduced #1
      immunization mouse cii #1
      epitope cartilage #1
      mem lglutamine #1
      c3hq mice cii #1
      kgf thymus #1
      heterologous cii #1
      pc4 pc117 #1
      caia model #1
      glycosylated epitope structures #1
      targeted mutation ncf4 #1
      cii polymer #1
      mice interferon gamma #1
      l012 vivo imaging #1
      arthritis suppression #1
      ros mip #1
      experimental arthritis articular #1
      ifa rats #1
      g6pi acute arthritis #1
      oxa backcrosses #1
      antitype collagen #1
      cii h2p #1
      exacerbation arthritis #1
      genes antibodies #1
      joint proteins #1
      clever1 type macrophages #1
      ncf1 ncf1m1j mutation #1
      paamcryogel #1
      ciic1 ciif4 #1
      autoimmune response cii #1
      arthritis pnipaam #1
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      fpr1 agonist neutrophils #1
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      cia oia #1
      ltabncr3 #1
      arthritis #1
      rat rt1ba genes #1
      cia congenic arthritis #1
      citrullinated collagen arthritis #1
      susceptibility cia #1
      surface redox levels #1
      cartilage explants m2139 #1
      cartilagespecific protein #1
      arthritis autoimmune #1
      collagen immunization #1
      disease c4bp #1
      functional nox2 complex #1
      glycosylated cii #1
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      lpr mice granulocytes #1
      polychondritis autoimmune disease #1
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      methodspurified #1
      rs201802880 #1
      nasal treatment ctbcii #1
      nzb dth #1
      cii256−270 #1
      h2q h2r #1
      flss tlr3 expression #1
      collagen iiinduced arthritis #1
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      cells heterologous cii #1
      cia caia #1
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      cxi 6 #1
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      effects ciif4 #1
      epitopes cb11 fragment #1
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      pepsin cii #1
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      hyaluronanreceptor cd44 #1
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      lymphocytes cartilage #1
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      presence arthritogenic mabs #1
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      phytol rna #1
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      male mice arthritis #1
      constant light order #1
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      animal models complexity #1
      mir144 tlr2 expression #1
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      chronic relapsing arthritis #1
      u1 epitope #1
      mip ncf4 #1
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      keratinocytes dth reaction #1
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      acpas specificity #1
      nod loci genes #1
      functional selective fpr1 #1
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      large numbers hybridomas #1
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      cix disease #1
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      cia b10q #1
      dnp epitopes lysine #1
      cii treatment #1
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      qtl animal genes #1
      susceptibility collageninduced arthritis #1
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      dth nzb mice #1
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      collagen arthritis progesterone #1
      270 peptide #1
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      reactivity cb268 #1
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      ciif4 mab #1
      rats chronic disease #1
      chromosome f1 males #1
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      cia pia #1
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      arthritogenic mabs cii #1
      ncf1 genes #1
      cia11 #1
      cartilage explants mabs #1
      cartilaginous joints #1
      oestrogen‐induced suppression #1
      genetic variants ncf1 #1
      rabeximod inflammatory cells #1
      collagen epitopes #1
      cia opportunities #1
      immunodominant cii #1
      models rheumatoid #1
      carcinoma tumors ros #1
      type epitopes #1
      antibodies pc4 #1
      selfcii #1
      phytol arthritis #1
      spread psoriasis #1
      immune cartilage #1
      molecule aq #1
      h2w3 #1
      role major epitopes #1
      incidence arthritis #1
      cd200 btla #1
      controlling onset #1
      peritonitis transgenic #1
      rabeximod arthritis #1
      b10dr4ncf1 mice cii #1
      confers arthritis susceptibility #1
      development collagen #1
      acute phase arthritis #1
      polymorphism ncf1 #1
      genetic background rats #1
      cii cb fragments #1
      autoimmune arthritis apcs #1
      pepsin arthritis #1
      oxidases polymers #1
      immunospecific reactions #1
      periodontitis rats pia #1
      elevated th17 cells #1
      tlr3 tlr3 expression #1
      dominant hypersensitivity #1
      epitopes cb10 fragment #1
      cxi rats #1
      mcaia ncf1 #1
      disease transgenic models #1
      arthritis ncf1 allele #1
      rats terpenes #1
      experimental autoantibodies #1
      treatment physiological doses #1
      citrulline collagen #1
      peripheral cells alphachains #1
      arthritis monoclonal arthritis #1
      thymectomy transgenes #1
      concentrations cii #1
      arthritis control mice #1
      role ncf1 #1
      cartilage collagen type #1
      sialadenitis incidence #1
      cells galactosylated peptide #1
      estrogen immune responses #1
      m1s1a #1
      rt1f haplotype #1
      concentrations rat cii #1
      kgf cia #1
      ciiinduced #1
      rats cxi #1
      congenic #1
      cii ncf1 #1
      collagens antibody #1
      il10 cia #1
      hufcgammariia #1
      glycoprotein alpha1microglobulin #1
      rats synthetic peptide #1
      aq glycopeptide #1
      arthritis tlr3 #1
      genistein collagen #1
      beta 812 #1
      β1helix #1
      dominant susceptibility loci #1
      frequency chronic arthritis #1
      rats ncf1 gene #1
      dba 1jpfp #1
      polymorphism autoimmune diseases #1
      arthritis anticii abs #1
      glycosylated epitope #1
      f1 males influence #1
      collagen hybridomas #1
      lew avridineinduced arthritis #1
      experimental autoimmunity cells #1
      collagen induced #1
      cii 256270 peptide #1
      fls ppt medium #1
      critical restriction site #1
      antibody response cii #1
      collagen antibodies #1
      cii mab #1
      autologous type collagen #1
      arthritis b10q mice #1
      cia animal epitopes #1
      lnchc cholesterol metabolism #1
      eae2 locus #1
      ncf1 mutant mice #1
      ​methods #1
      aq molecule #1
      caia riiis segment #1
      extraarticular cartilage #1
      nodp nod #1
      chromosome cia #1
      rheumatoid arthritis cia #1
      hladrβ10402 #1
      arthritis males #1
      lewis oia #1
      collagen reactivity cxi #1
      synovial cells macrophages #1
      cia melatonin #1
      cells ncf1 #1
      tlr3 expression flss #1
      induced relapsing #1
      dba 1jpfp cia #1
      cxb10qf2 #1
      development aureus arthritis #1
      argltgrpgda #1
      citrullination cii #1
      human gpi protein #1
      increased salt exposure #1
      cii induced #1
      mice h2q #1
      pia cia #1
      cii dendritic cells #1
      blocking arthritis #1
      p47phox mutant #1
      rats antibody response #1
      severity arthritis #1
      collagen type‐ii epitope #1
      cageeffects #1
      diabetes sialadenitis #1
      mutant p47phox #1
      formation arthritis #1
      dependent autoimmune arthritis #1
      ncf1 339 #1
      immunization heterologous cii #1
      m2139 arthritogenic mab #1
      cii rats #1
      mediating arthritis #1
      stromal cells osteoclasts #1
      cii ciif4 #1
      citrullinated type collagen #1
      driven psoriatic arthritis #1
      cii human #1
      b10q dba 1f1 #1
      cxi pia #1
      ros antigens #1
      h2r h2q #1
      immune priming events #1
      bb2bb3 regulation #1
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      cii antibody #1
      human cii cartilage #1
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      kgf chondrocytes #1
      cii severe arthritis #1
      lewis rats pepsin #1
      dominant traits #1
      antibody ciic1 #1
      cii heterologous cii #1
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      cia21 cia22 #1
      h2p susceptibility #1
      riiis alleles eae2 #1
      inflammation caia #1
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      kupffer cells mir144 #1
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      cells mouse cii #1
      dendritic cells collagen #1
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      function p47phox #1
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      loci controlling diabetes #1
      371115tetramethyl2hexadecene1ol #1
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      susceptible cia #1
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      b10qc5δ #1
      collagen langerhans cells #1
      emulsions induction #1
      developed severe #1
      tlr3 expression tnfα #1
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      innate rats #1
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      dr4 glycopeptides #1
      hfdmets #1
      congenic cia40 #1
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      oxazolone inflammatory response #1
      cells arthritogenicity #1
      differential susceptibility cia #1
      ciilysdnp #1
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      cartilage cii #1
      nod incidence #1
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      nodq×b10q #1
      arthritogenicity cells #1
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      polyi pia rats #1
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      chronicity arthritis #1
      arthritis cia #1
      day ciispecific cells #1
      peptide agonist fmlf #1
      genetic regions #1
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      backcrosses nzb mice #1
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      function ncf1 gene #1
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      protein ncf1m1j mice #1
      inbred strains severity #1
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      dapia3 #1
      macrophages cii degradation #1
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      striking phenotypic similarities #1
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      anti collagen #1
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      increased incidence cia #1
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      cells caia #1
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      comp disease monitoring #1
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      antiidiotypic antibodies cd4 #1
      cartilage antibody #1
      b10q mice authors #1
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      illness terpenes #1
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      diagnostic accuracy acpa #1
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      cell recognition carbohydrates #1
      collagen arthritis iii #1
      mice l012 #1
      mice th1 cytokines #1
      hybridomas multispecific antibodies #1
      monoclonal arthritis arthritis #1
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      therapeutic cleavage igg #1
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      cii monoclonal arthritis #1
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      intracellular processing cii #1
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      greater osteoclasts #1
      cii h2q #1
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      eae5 pia4 #3
      type c2ta #3
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      pia6 #3
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      differences citrullinated peptides #3
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      recombination rt1a #3
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      igl genes #3
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      twins acpapositive #3
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      targeting toll #3
      knowledge genetic association #4
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      cb10 fragment #4
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      loci controlling #6
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      monoclonal encephalomyelitis autoimmune #6
      betaoestradiol #6
      tsst1 mice #6
      develop arthritis #6
      controls arthritis #6
      contrasting roles #6
      c57bl 6 background #6
      acpa specificities #6
      autoimmunity arthritis #6
      l3t4positive cells #6
      cell recognition #6
      hdac1 class #6
      ltab #6
      transgenic mice arthritis #6
      cia cd4 cells #6
      pv loss #6
      induced psoriasis #6
      animal genetic #6
      mediated vasculitis #7
      mbp peptide #7
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      antigens differentiation arthritis #7
      psoriasiform skin disease #7
      murine psoriasis #7
      animal immunization injections #7
      snecs #7
      mice constant darkness #7
      cab3 #7
      role raloxifene #7
      citrullinated peptide antigens #7
      isomerase peptide #7
      collagen epitope #7
      locus chromosome #7
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      arthritis strains #7
      cii apc #7
      cognate activation #7
      strains disease #7
      congenic mouse #7
      mouse collagen #7
      cia5 #7
      chronic experimental #7
      rheumatoid arthritis role #7
      g6pi #7
      oestrogen rats #7
      autoimmunity collagen #7
      type collagen #7
      congenic strains #7
      impaired induction #7
      rats phases #7
      periodontitis arthritis #7
      glycosylated collagen #7
      antibodies citrullinated antigens #7
      autoantibodies lymphocytes #7
      antibodyinduced arthritis #7
      nonarthritogenic #7
      region syntenic #7
      arthritis type collagen #7
      conventional environment #7
      regulatory cells macrophages #7
      impact cia #7
      castrated females #7
      cia mice #7
      protective influences #7
      ean animals #7
      raassociated molecules #7
      autoantibodies citrullinated peptides #7
      chronic phase arthritis #7
      yaa gene #7
      cii anti #7
      3xi #7
      arthritis genes #7
      induction arthritis #7
      analysis crosses #7
      responses cii #7
      response immunization #7
      acpa titres #7
      cryogel column #7
      autoimmune human #7
      aplec #7
      collagen arthritis cia #7
      collagen arthritis rats #7
      polychondritis relapsing #7
      macrophages alternative activation #7
      hydrolases polymorphism #7
      symptoms disease onset #7
      ciireactive cells #7
      antibody vivo #8
      treatment monoclonal #8
      fcγr2b #8
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      42 rats #8
      oia2 #8
      rheumatoid autoimmunity #8
      arthritis lymphocytes #8
      ifa cii #8
      patients type collagen #8
      medium mem #8
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      t‐cell priming #8
      heterologous peptide #8
      autoantibodies collagen type #8
      parathyroid glands receptors #8
      neutrophil cytosolic #8
      expression hdac3 #8
      hlase alleles #8
      autoantibodies subset #8
      polymeric cryogels #8
      297 cases #8
      autoimmune congenic mice #8
      chronic autoimmune arthritis #8
      rt1f #8
      ros interplay #8
      destructive effects #8
      α1‐microglobulin #8
      sialadenitis mrl #8
      mbp mog #8
      hybridomas antibodies #8
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      rats mhc #8
      dominant cell epitope #8
      antibodies acpas #8
      chromosomes loci #8
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      eae genetic encephalomyelitis #8
      humans experimental arthritis #8
      persistent joint pain #8
      mumt mice #8
      antigenspecific priming #8
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      illness igg #8
      supermacroporous cryogel #8
      cosphox #8
      mice techniques #8
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      lyme arthritis severity #8
      murine locus #8
      eae3 #8
      typeii collagen #8
      hdac3 expression #8
      induced neuropathology #8
      onset incidence #8
      experimental autoimmune disease #8
      incidence cia #8
      autologous peptide #8
      oligomeric matrix #9
      posttranslational glycosylation #9
      class allele #9
      hgpi325 #9
      bovine cii #9
      development autoimmune arthritis #9
      b10riii mice #9
      reduced arthritis #9
      variants acpa #9
      human immunopeptidome #9
      experimental genes #9
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      2 nadph #9
      psychological tyrosine #9
      ox19 #9
      autoimmunogenic #9
      antibodies vivo #9
      arthritis cross #9
      hitr #9
      specific nox2 #9
      inbred dba mice #9
      arthritis skg mice #9
      alpha1inhibitor3 #9
      idiotype‐specific #9
      postmenopausal arthritis #9
      eae immunization #9
      response mouse #9
      rt1u #9
      mammalian disease models #9
      ean myelin #9
      inbred lew tlymphocytes #9
      cia transgenic mice #9
      oil adjuvants #9
      patients acpas #9
      early joint erosions #9
      adaptive inflammation #9
      rheumatoid joints #9
      disease strains #9
      illness receptor #9
      serum interferon #9
      acpas patients #9
      antibody alpha #9
      collagen complement #9
      differentiation autoimmune #9
      pristane #9
      il10 role #9
      histone 1 hdac1 #9
      effects mabs #9
      bound carbohydrates #9
      animal models urgent #9
      rheumatoid autoantibodies #9
      murine collagen #9
      nodp #9
      avridine #9
      experimental arthritis rats #9
      intranasal animals arthritis #9
      collagen female #9
      loci rats #9
      specific sets #9
      induced metabolic syndrome #9
      mouse peptide #9
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      monoclonal antigens rats #10
      immunization rats #10
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      severe erosive #10
      dense fractions #10
      acutephase response rats #10
      rats lewis rats #10
      knockout nadph #10
      cartilage arthritis #10
      collagen autoimmunity #10
      hlase smoking #10
      mice genistein #10
      monoclonal arthritis #10
      mutated mice #10
      citrullinated antigen #10
      mbp peptides #10
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      cells development #10
      tertbutylacrylamide #10
      reactivity acpas #10
      extracellular cartilage #10
      cells increased production #10
      cd4 cells spleen #10
      mice cii #10
      inbred dba #10
      autoimmune disease humans #10
      abp gene #10
      nih heterogeneous stock #10
      experimental cartilage #10
      axotomized motor neurons #10
      o2• h2o2 #10
      endogenous collagen #10
      antibodies specific #10
      pain animal models #10
      oestrogen #10
      mice nadph #10
      prl effects #10
      genetic experiments #10
      alpha collagen chains #10
      cii mice #10
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      cartilage oligomeric #10
      acpa diagnosis #10
      cartilage collagen fibrils #10
      onset chromosome #10
      stock mice #10
      activation male #10
      h2ap #10
      passive transfer experiments #10
      rheumatoid arthritis dr4 #10
      presence acpa #10
      antibody collagen #10
      development severity #10
      tailbase #11
      cells pia #11
      nodb10h2b mice #11
      antibody type collagen #11
      arthritis absence #11
      rat arthritis #11
      rat liver rats #11
      mhc control #11
      naïve cells cells #11
      inflammatory arthritis role #11
      chronic arthritis #11
      antigen variability #11
      2xi #11
      cia7 #11
      gad6 #11
      stromal cells macrophages #11
      individuals onset #11
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      dss wt #11
      lentiviral vector expression #11
      monoclonal rheumatoid factors #11
      rat collagen #11
      mice mhc #11
      loci regulating #11
      development rheumatoid #11
      84–102 #11
      ptpn22 smoking #11
      fragments anti #11
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      potential autoantigens #11
      antibodies association #11
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      mice cd1 #11
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      species respiratory #11
      icmediated #12
      stages pathogenesis #12
      associations antibodies #12
      cross rats #12
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      mbp response #12
      antibodies structures #12
      genetic contamination #12
      illness sex characteristics #12
      cii patients #12
      natural polymorphism #12
      α1ii #12
      myelin ean #12
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      riiis #12
      onset symptoms #12
      study arthritis #12
      rats cia #12
      chronic erosive arthritis #12
      autoimmune monoclonal antigens #12
      peptide study #12
      loci disease #12
      psoriasis arthritis #12
      encephalomyelitis induced #12
      backgroundantibodies #12
      major haplotype #12
      increased litter size #12
      type collagen immunization #12
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      psoriasis mouse model #12
      hydroxylysines #12
      reduces severity #12
      cell responses cii #12
      role arthritis #12
      mutation nadph #12
      lymphoid cells development #12
      animal immunohistochemistry #12
      treatment experimental arthritis #12
      fpr2 agonists #12
      bovine type collagen #12
      mice comp #12
      structure antibodies #12
      stage cia #12
      rats expression #12
      matrilin #12
      lung macrophages mice #12
      nonselfdiscrimination #12
      serum concentrations comp #12
      frequencies antibodies #12
      mutated mouse #12
      pia1 #12
      t‐cell epitope #13
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      cells salivary glands #13
      arthritis knowledge #13
      joints blood #13
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      epitope immunization #13
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      oxidative regulation #13
      l012 #13
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      genes mouse chromosome #13
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      dba molecular #13
      expression egfp #13
      rfigg #13
      antibodies citrullinated proteins #13
      nonobese diabetic mouse #13
      advanced intercross #13
      hladrb1 ptpn22 #13
      mannan #13
      behavioral alterations rats #13
      major loci #13
      24dinitro1fluorobenzene #13
      doses ici #13
      ho4 #13
      species deficiency #13
      complement complement activation #13
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      oxidase nox2 #13
      idd5 #13
      immunohistochemistry interferon #13
      mouse strains #13
      cell epitope #13
      μ chain #13
      nos2derived #13
      anticii #13
      dr1 transgenic #13
      ccp2 antibodies #13
      factor isotypes #13
      collagen disease #14
      autoimmune arthritis #14
      loci rheumatoid #14
      blymphocyte female humans #14
      specific inflammation #14
      efficient promotion #14
      autoimmunity animals #14
      smallmolecule compound #14
      murine collageninduced arthritis #14
      b6n mice #14
      peptides anti #14
      mhc class region #14
      aggregated nets #14
      immunized rat #14
      presence mcv #14
      molecular disease models #14
      loci interaction #14
      cia expression #14
      collagen comp #14
      arlacel #14
      humans nadph #14
      macrophages immune response #14
      protein collagen #14
      experimental interferon #14
      immune regulators #14
      osteoclasts vivo #14
      gut protection #14
      arthritic paws #14
      thr233 #14
      antifilaggrin antibodies #14
      nasal inhalation #14
      involvement cells #14
      candidate autoantigens #14
      sirt1 mmp9 #14
      deficient production #14
      citrullinated peptides patients #15
      treatment cia #15
      raloxifene estradiol #15
      osteoporosis development #15
      rheumatoid arthritis presence #15
      ros cii #15
      exaggerates #15
      antigenic epitope #15
      tflask #15
      congenic rats #15
      antibodies arthritis #15
      involvement pathogenesis #15
      murine cia #15
      regulation adaptive immunity #15
      cdr regions #15
      rat genetics #15
      neuritis rats #15
      mice type collagen #15
      rt1a #15
      2 weight #15
      monolithic cryogel #15
      amps development #15
      mice immunization #15
      arthritis role #15
      translationally modified #15
      aire mtec #15
      lentiviral gene delivery #15
      integrated bioprocess #15
      cultured human chondrocytes #15
      anticollagen #15
      dcii #15
      monoclonal arthritis rats #15
      nodb10h2b #15
      presence anticarp antibodies #15
      experimental allergic neuritis #15
      polychondritis #15
      arthritis development #15
      mhc class molecule #15
      apcs macrophages #15
      immune complex formation #15
      rats monoclonal antigens #15
      type collagen development #15
      levels natural antibodies #16
      oligomeric matrix protein #16
      pparγ lxrα #16
      disease mice mice #16
      autologous collagen #16
      n305 #16
      acute inflammation mice #16
      mumt #16
      subspecificities #16
      class transplantation #16
      development rheumatoid arthritis #16
      anti‐t #16
      epitopes mice mice #16
      antinuclear autoimmunity #16
      lew1 #16
      hla–drb1 shared epitope #16
      nonglycosylated form #16
      congenic mice mice #16
      rheumatoid arthritis genes #16
      rats experimental arthritis #16
      matrilin proteins #16
      rheumatoid factor production #16
      cep1 #16
      lethal inflammatory #16
      indirect genetic predisposition #16
      fewer osteoclasts #16
      males onset #16
      genes animals #16
      arthritis cii #16
      mhc genes #16
      rno10 #16
      mhcii ciita #16
      staphylococcal arthritis #16
      rt1 #16
      h2p #16
      arthritis severity mice #16
      human fcγriia #17
      cab4 #17
      nox2 derived #17
      leuphe #17
      genistein mice #17
      animals congenic #17
      arthritis rheumatoid autoantibodies #17
      mice rheumatoid arthritis #17
      allergic neuritis #17
      native denatured #17
      collagen induced arthritis #17
      triplehelical conformation #17
      cartilage collagen #17
      collagen specific #17
      strains lymphocytes #17
      polyphosphate4 #17
      cells collagen #17
      inbred lew #17
      periodontitis antibodies #17
      clever1 #17
      cells female mice #17
      rt1av1 #17
      progesterone development #17
      skg #17
      ethanol development #17
      rats lewis #17
      rheumatoid arthritis subsets #17
      cells presenting cells #17
      onset rheumatoid arthritis #17
      spleen peyers patches #17
      autoimmune illness #18
      day arthritis #18
      addition ros #18
      disease duration onset #18
      day immunization #18
      anti cd44 #18
      salivary glands mice #18
      purified anti #18
      moginduced eae #18
      keratinocytes induction #18
      galactose moiety #18
      cuiiida #18
      short‐term administration #18
      arthritis anti #18
      hybridomas mice mice #18
      ealkene #18
      collagen autoantibodies #18
      joint inflammatory #18
      langerhans cells cells #18
      dra0101 #18
      h2z #18
      ros data #18
      adjuvant arthritis rats #18
      genes spleen #18
      humanized transgenic mice #18
      expression lxrα #18
      phenotypic feature #18
      cartilage type collagen #18
      defined epitope #18
      future utility #19
      supermacroporous #19
      cia eae #19
      inflammatory attack #19
      protein comp #19
      new avenues #19
      elisa cia #19
      mrl mp mice #19
      three‐dimensional culture #19
      suppression dth #19
      collagen response #19
      castrated female rats #19
      vivo elimination #19
      cd4 transgenic #19
      trimolecular complex #19
      rats snp #19
      protective alleles #19
      citrullinated proteins acpa #19
      tbetarii gene #19
      blood monocytes neutrophils #19
      gly262 #19
      mice develop #19
      peyers patches spleen #19
      mice congenic mice #19
      beta oestradiol #19
      single intradermal injection #19
      patients polychondritis #19
      response mbp #20
      5p14 #20
      nox1deficient mice #20
      matrilin1 #20
      fls tnfα #20
      antibody treatment #20
      mbp rats #20
      knockout mice transgenic #20
      loci chromosomes #20
      mice cia #20
      stress phospholipids #20
      enhanced tcr #20
      littermate #20
      inflammation mice #20
      ciita mhcii #20
      role nox #20
      experimental autoimmunity #20
      rt1d #20
      5r5 #20
      development disease #20
      ncr3 #20
      monkeys rodents #20
      imaging reactive #20
      highly susceptible #20
      underlying gene #20
      mhc class alleles #20
      prominent infiltration #20
      progesterone oestrogen #20
      pvg1av1 #20
      glycosylated #20
      serm raloxifene #20
      human rheumatoid arthritis #20
      cells adaptive immune #21
      chronic relapsing #21
      triplehelical peptides #21
      igg fcgammar #21
      onset severity #21
      genes controlling #21
      cia treatment #21
      linomide treatment #21
      arthritis pregnancy #21
      muscle ros #21
      diseases lymphocytes #21
      rats development #21
      supermacroporous cryogels #21
      suppressor cytotoxic cells #21
      nox2 activity #21
      α1acidglycoprotein #21
      positional cloning #21
      granule mobilization #21
      nox2 mice #21
      drb11001 #21
      pathogenesis rheumatoid #21
      illness autoimmune #21
      mice mutant strains #21
      nitratenitriteno pathway #21
      n286 #21
      olahsd #21
      n141 #21
      experimental rheumatoid #21
      ean rats #21
      individual acpa #21
      conserved haplotype #21
      serum levels comp #21
      rats nonalcoholic steatohepatitis #22
      270 #22
      experimental phenotype #22
      antiidiotypic antibody #22
      vh j558 #22
      semiallogenic #22
      ul1 #22
      cultured hepatic cells #22
      induced eae #22
      animal epitopes humans #22
      c57bl mice subfamily #22
      identification susceptibility genes #22
      ccp negative #22
      samples onset #22
      association pv #22
      81a #22
      mice independent #22
      determinant selection #22
      rats loss #22
      response myelin #22
      loss collagen #23
      comp #23
      rats inbred lew #23
      mace association #23
      monoclonal antigens autoimmune #23
      4npa #23
      cryogel beads #23
      citrullinated antigens #23
      citrullinated protein #23
      experimental chromatography #23
      phage clones #23
      17 betaoestradiol #23
      immunopeptides #23
      onset cia #23
      complex influences #23
      peptide activation #23
      antibodies acpa #23
      arthritis type #23
      lymphocytes amino #23
      cells presentation #23
      cells b10 #23
      inflammation absence #23
      mbp eae #23
      animal genes #23
      anti‐cd5 #23
      citrullinated epitopes #23
      b10r #23
      castration rats #23
      experimental autoimmune diseases #23
      diseases autoimmunity #23
      tgfbeta resistance #23
      levels comp #24
      ftirm #24
      subloci #24
      mouse models development #24
      experimental lupus #24
      postpartum flare #24
      new mouse #24
      inflammation arthritis #24
      animal epistasis #24
      secondary immune response #24
      antinuclear apoptosis #24
      severity ali #24
      cells c3h #24
      controls anti #24
      mediated arthritis #24
      loci chromosome #24
      autoantibodies rheumatoid #24
      chronic autoimmune diseases #24
      339 #24
      monoclonal anti #24
      experimental cells #24
      y35 #24
      rat induction #24
      severity chronicity #24
      flss patients #24
      mice nox2 #24
      c57bl 10 mice #24
      immunization development #25
      specific epitopes #25
      relapsing polychondritis #25
      production monoclonal #25
      monocytes nadph #25
      tolerized rats #25
      ros #25
      common autoimmune disease #25
      complex male #25
      autoimmune messenger #25
      cix #25
      beta lymphocytes #25
      cell hybridomas #25
      bnda #25
      inbred lew rats #25
      massive infiltration #25
      immunodominant epitope #25
      arthritis experimental arthritis #25
      murine lyme arthritis #25
      rat mhc #25
      proteinarginine deiminase type #25
      congenic animals #25
      autoimmune diseases humans #25
      arginine arthritis #25
      8 antibodies #25
      parasitemia survival #25
      collagen cartilage #25
      b6 balb #25
      interleukin2 mice receptors #25
      cells immunization #25
      rno4 #25
      autoantibody response #25
      nitrophenylalanine #26
      eae development #26
      cells joints #26
      polychondritis rp #26
      igg2a mice #26
      gene regions #26
      glutamax #26
      local exposure #26
      hydrocarbon oil #26
      cb11 #26
      autoantibodies citrullinated proteins #26
      viable chondrocytes #26
      anti citrullinated #26
      granulocytes cells #26
      mice gammadelta cells #26
      helperinducer animals antibodies #26
      post translationally #26
      pointmutation #27
      perforin deficiency #27
      hladrb1 shared epitope #27
      nonmhc genes #27
      immunodominant response #27
      antibodies type #27
      individuals antibodies #27
      disease immunoglobulin #27
      trypsination #27
      ccp2 #27
      interleukin21 tlymphocytes #27
      intercrossed #27
      innate interleukin10 #27
      rheumatoid factor isotypes #27
      physiological level #27
      c1i #27
      immunospecific #27
      pannus tissue #27
      lysine position #28
      protein peptides #28
      severity day #28
      w3 25 #28
      antibodies mab #28
      nr8383 #28
      rat strain #28
      upregulation cytokines #28
      mediated effects #28
      anti rat #28
      eae susceptibility #28
      onset day #28
      antigenspecific tolerance #28
      mrna ifngamma #28
      animal models neurodegeneration #28
      chronicity #28
      ros induction #28
      antily6g #28
      autoimmune inflammatory #28
      cartilage vivo #28
      cia3 #28
      hiit exercise #29
      rfigm #29
      chronic dss #29
      suboptimal doses #29
      peptide anti #29
      cfa cia #29
      parotid secretory protein #29
      ls2616 #29
      absence inflammation #29
      antibody producing cells #29
      ros production macrophages #29
      presence synovial fluid #29
      246trinitrophenyl #29
      phenomes #29
      acpa #29
      membrane lymphocytes #29
      glucose transport capacity #29
      immunopathogenicity #29
      smoking presence #29
      mice mab #29
      chain collagen #30
      hlase #30
      increased salt #30
      paws #30
      vpba #30
      treatment raloxifene #30
      disease immunity #30
      dba mice #30
      linkage disease #30
      plasminogendeficient mice #30
      synovial cells patients #30
      variable heavy chain #30
      chronic autoimmune #30
      ctla4 mice #30
      development experimental #30
      translational rats #30
      cultivation cells #30
      acpa fine #30
      vivo exercise #30
      11 cells #30
      adult thymectomy #30
      alphabetat #30
      metabolic syndrome rats #30
      vgenes #30
      nox2 nox1 #31
      synovial fluid blood #31
      human type collagen #31
      acute‐phase response #31
      ige cd23 #31
      expressing cells #31
      drugs addition #31
      perpetuated #31
      comparative genetic analysis #31
      pristaneinduced lupus #31
      littermate controls #31
      monoclonal antibody production #31
      psoriasis model #31
      trimolecular #31
      selfprotein #31
      apc development #31
      immunization #31
      phytol #31
      hiit training #31
      common chain #31
      disease development #31
      rats autoimmune #31
      receptor preference #32
      nonb cells #32
      cells uterus #32
      congenic mice #32
      polymorphic genes #32
      presence acpas #32
      nadph oxidases nox #32
      mucosal tolerance #32
      nodes mice #32
      role osteoclastogenesis #32
      type antibody #32
      methods serum samples #32
      genomewide genotyping #32
      hladrb104 #32
      11 cell #32
      epitope antibodies #32
      rt11 #32
      beta mice #32
      ra33 #32
      caia mice #32
      h2aq #32
      influence genes #32
      differentiation arthritis #32
      steen #32
      cell ratio #32
      arthritis therapy #32
      ros rns #32
      specificity function #32
      acpa rheumatoid arthritis #32
      bound peptides #32
      tolerance immunization #33
      modified collagen #33
      arthritic mice #33
      tcell receptor #33
      antigenpresenting cells cells #33
      role vav1 #33
      autoantibody activity #33
      multiplex analysis #33
      type cross #33
      epitopes antibodies #33
      induced immunization #33
      skews #33
      autoimmune demyelinating disease #33
      rheumatoid joint #33
      cytosolic factor #33
      delayed type #33
      fpr1 #34
      chronic polyarthritis #34
      interferon activity #34
      promiscuous expression #34
      neurodegeneration role #34
      nox2 deficiency #34
      patients animal models #34
      c4bp #34
      cells dendritic cells #34
      joint pathology #34
      natural antibodies nabs #34
      heterogeneous stock #34
      monoclonal rheumatoid #35
      accessible sites #35
      autoreactive #35
      plasminogen deficiency #35
      acs stroke #35
      nets neutrophils #35
      patients populations #35
      1xi #35
      antirat #35
      vdr cells #35
      psoriasiform skin #35
      phagotope #35
      hybridomas #35
      triple helical #35
      arthritis disease #35
      major regulators #35
      infectious disease models #35
      antiarthritis #35
      complex arthritis #35
      development chronic #35
      destructive arthritis #35
      phagocyte #36
      flow cytometry expression #36
      specificity sera #36
      female histocompatibility #36
      nk cells recognition #36
      dth #36
      induction tregs #36
      h2r #36
      variance animals antibodies #36
      comparative genetics #36
      protein specific #36
      animals antigen #36
      arthritis cartilage #36
      cii cfa #36
      dinitro1 #36
      tolerance tlymphocytes #36
      cartilage joints #36
      oxidases rna #36
      techniques mice #36
      h2g7 #36
      synthetic glycopeptides #37
      immunopathological features #37
      c129 #37
      mif pathogenesis #37
      oxidases oxidation #37
      recombinant vaccine #37
      rich lipid #37
      cii protein #37
      encephalomyelitis #37
      peptides binding #37
      dba1 #37
      lymphocytes disease #37
      joint cartilage #37
      spontaneous arthritis #37
      susceptibility autoimmune diseases #37
      genetic control #37
      acpa positive #37
      role gamma interferon #37
      cldn4 #38
      nitrogen species #38
      animal models pain #38
      snat #38
      antibodies animals #38
      innovative tools #38
      human blood neutrophils #38
      sialophorin #38
      cochranmantelhaenszel test #38
      target autoantigens #38
      ym1 #39
      clonal expansion cells #39
      cell tolerance #39
      autoreactive cells #39
      allogeneically #39
      acpa response #39
      nzw #39
      ccia #39
      wasting syndrome #39
      b6n #39
      benoist #39
      resultsrats #39
      data myelin #39
      nfr #39
      measurement activity #39
      endoβnacetylglucosaminidase #39
      oestrogen treatment #39
      adjuvant induced #40
      isostere #40
      genetic complexity #40
      peptide cell #40
      positive rheumatoid #40
      addition impact #40
      disease animal models #40
      rt1c #40
      antigens arthritis #40
      polyclonal cell activation #40
      immunocap isac #41
      priming phase #41
      congenic mapping #41
      aq #41
      mhc haplotype #41
      genes loci #41
      autoimmune inflammatory diseases #41
      severity incidence #41
      ncii #41
      rat myelin #41
      autoimmune #41
      rats anti #41
      effects experiments #41
      expected onset #42
      th17 axis #42
      cartilage bone destruction #42
      species receptors #42
      fibroblasts mice #42
      mhc class class #42
      spleen weight #42
      antibody isotypes #42
      p38 mapk nfκb #42
      ptpn22 locus #42
      pineal gland melatonin #42
      articular collagen #42
      drb1 shared #42
      mice autoimmune #43
      cd11bly6g #43
      crosses genetic #43
      spinal glia #43
      pc8 #43
      congeneic #43
      rats sex #43
      kgf treatment #43
      collagen #43
      anticyclic #43
      arthritis data #43
      type‐ii #43
      lew lymphocytes #43
      lew rats #43
      anticitrullinated #43
      immunodominant epitopes #43
      autoreactive cell #43
      treatment autoimmune diseases #43
      c4bbinding protein c4bp #44
      chloro23 #44
      mathis #44
      inflammation animals #44
      homozygous form #44
      neuritis ean #44
      epitopes lymphocyte #44
      genetic linkage analysis #44
      mice mice autoimmune #44
      mice adulthood #44
      peptide induced #44
      provocations #44
      defensins humans #44
      addition order #44
      phagotopes #45
      relapsing disease #45
      outbred rats #45
      nzb #45
      disease histocompatibility #45
      susceptibility arthritis #45
      chromosome development #45
      genetic encoding #45
      potent suppression #45
      lower severity #46
      rat2 #46
      isosteres #46
      neuritis autoimmune #46
      affinity purified #46
      c227 #46
      mhc class humans #46
      alphachains #46
      disease induction #46
      posttranslationally #46
      carp antibodies #46
      locus controlling #46
      specific tolerance #46
      eae mbp #46
      cocrystallisation #46
      protective allele #47
      idiotypic antibody #47
      antibody reactivities #47
      posttranslational rats receptors #47
      rheumatoid factors #47
      f1 hybrid mice #47
      association hladrb1 alleles #47
      complex mediated #47
      diagnostic accuracy diagnosis #47
      intercrosses #47
      mice carrying #48
      mice nzb #48
      lupus disease #48
      experimental arthritis mice #48
      collagen glycosylation #48
      tlr12 #48
      cia rats #48
      humanized model #48
      f1 crosses #48
      peptide recognized #48
      synovial lining layer #48
      antibody specificity #48
      collagen peptide #48
      γchains #48
      acetylchitobiose #48
      monoclonal autoimmune diseases #49
      polyvinylcaprolactam #49
      immune nervous #49
      class major #49
      comp levels #49
      tcell stimulation #49
      sex genes #49
      bystander activation #49
      mice caia #49
      experimental crosses #49
      mouse cartilage #49
      histone hdacs #49
      glutamine uptake #50
      parathyroid cells #50
      dependent chronic #50
      loci animals #50
      cytometry analyses #50
      anticarbamylated protein #50
      mice tolerance #50
      animal cell culture #50
      complex region #50
      disease rats #50
      alagly #50
      ciiia #50
      inflammation kynurenine #50
      glycosylated form #50
      monoclonal epitopes #50
      antigenantibody #50
      lentiviral particles #51
      antibodies cells #51
      autoantibodies rheumatoid arthritis #51
      runting #51
      c57bl 6j background #51
      rheumatoid factor activity #51
      inbred c57bl autoimmune #51
      derived type #51
      aire mice #51
      tracheal cartilage #51
      tolerized #51
      cells ova #51
      delayed immunization #51
      evidence animal models #51
      fewer cells #51
      antigenpresenting cells #52
      macrophages skin #52
      xor activity #52
      model collagen #52
      matrix protein #52
      ptpn22 #52
      cartilage erosion #53
      carbamylated proteins #53
      lysosomal compartments #53
      arthritis induction #53
      physiological doses #53
      melatonin day #53
      antibodies epitopes #53
      protein antibodies #53
      induced autoimmunity #53
      production reactive #53
      patients rheumatic conditions #53
      aged peptides #53
      gastric parietal cell #53
      triple helical structure #53
      nodes lymphocyte #54
      predating #54
      animals autoimmune #54
      major epitope #54
      rats social isolation #54
      carbamylated protein #54
      crossbreeding #54
      development individuals #54
      melatonin animals #54
      antigens myelomonocytic arthritis #54
      strain rats #54
      imitating #54
      yaa #54
      arthritis genetic #55
      autoimmune nzb #55
      complex genetic disease #55
      autoimmune reactions #55
      susceptibility autoimmune disease #55
      macrophage mannose receptor #55
      inflammatory manifestations #55
      mhc #56
      animals antibody #56
      labels superoxide #56
      alpha1microglobulin #56
      cells salivary #56
      selfreactive cells #56
      new animal #56
      antibodies #57
      arthritis pathogenesis #57
      igg abs #57
      development autoimmune #57
      vivo depletion #57
      animals antirheumatic #57
      cd1 mice #57
      antibodies bind #57
      collagen sequence #57
      schafer #58
      rat type #58
      urokinase activity #58
      oestrogen progesterone #58
      peptide response #58
      chronic eae #58
      anticarp antibodies #59
      genes mhc #59
      encephalitogenicity #59
      anti cd8 #59
      hydroxylase diet #59
      resistance eae #59
      cartilage matrix protein #59
      oligoclonal igg bands #59
      articular joints #59
      anti cell #59
      macrophage mannose #60
      alternative activation macrophages #60
      hpaaxis #60
      inflammatory cells macrophages #60
      dichotomous effects #60
      joint erosions #60
      protein peptide #60
      assay epitopes #60
      immunohistopathology #60
      epitope spreading #61
      incidence severity #61
      alpha1m #61
      cells innate immune #61
      major histocompatibility #61
      serum comp #61
      experimental evoked potentials #61
      species reactive #61
      experimental rats rats #61
      differentiation myelomonocytic arthritis #61
      syngeneically #62
      interferon‐β #62
      toxin1 #62
      adaptive immune #62
      mice susceptibility #62
      reduced oxidative #62
      cyclic sensitivity #62
      autoantibody formation #62
      antigens class histocompatibility #62
      basic characterization #62
      placenta uterus #62
      fpr2 #62
      hypersensitivity dth #63
      constant darkness #63
      mice polyi #63
      transfer animals #63
      duval #63
      collagen cell #63
      specific stages #63
      protein disease #63
      glycoprotein myelin #63
      peptide specific #63
      delayed interferon #63
      mog1 #63
      nadph oxidases #63
      induced experimental #63
      post‐partum #63
      specificity tumor #63
      rats strain #63
      igaproducing cells #63
      tolerance model #64
      maternal origin #64
      secondary immune #64
      role apc #64
      lower capacity #64
      freund adjuvant #64
      flss #65
      major subset #65
      induced suppression #65
      weight variation #65
      hindpaws #65
      model chronic #65
      histocompatibility complex #65
      autoimmunity humans #65
      spontaneous disease #66
      hladr2 #66
      phagocytosis oxidative burst #66
      resemblances #66
      experimental lymphocytes #66
      chromosomes mammalian #66
      thy1 antigen #66
      peripheral joints #66
      acute arthritis #66
      negative rheumatoid #66
      multispecificity #66
      rheumatoid synovial cells #66
      experimental allergic #67
      fibrinogen genotype #67
      experimental encephalomyelitis #67
      strains susceptible #67
      myelomonocytic arthritis #67
      development cell #67
      mice cell #67
      dendritic cells epitopes #67
      endos #67
      key interactions #67
      rheumatoid arthritis susceptibility #67
      mice induced #67
      severity periodontitis #68
      individuals positive #68
      anti carp #68
      sodium diethyldithiocarbamate #68
      class region #68
      tolerized mice #68
      cells mhc class #68
      frequent infections #68
      complex class #68
      helper phenotype #68
      iggrf #68
      female sex hormones #68
      rheumatoid chromosomes #68
      direct damage #69
      vertebrate immune #69
      cells mouse #69
      relapsing #69
      zap‐70 #69
      rheumatoid disease #69
      lymphocytes chronic #69
      frequency antibodies #69
      role cells #70
      translationally #70
      response type #70
      mrl mice #70
      prolonged graft survival #70
      presence rheumatoid factor #70
      immunoglobulin interferon #70
      cb10 #71
      isolated rats #71
      swr #71
      human psoriasis #71
      expression pparγ #71
      cartilage mice #71
      susceptibility female #71
      ztm #71
      napdh #72
      autoimmunity lymphocytes #72
      interphalangeal joints #72
      naïve mice #72
      dark agouti rats #72
      antibodies binding #72
      lathyritic #72
      delayedtype hypersensitivity dth #72
      study antibodies #72
      type ifn signature #73
      mrl lpr #73
      treatment stages #73
      knockout protein processing #73
      environmental lighting #73
      bovine type #73
      oxidase complex #73
      membrane animals #73
      species ros #73
      pregnancyinduced #74
      peptides sequences #74
      igarf #74
      hypersensitivity delayed #74
      antigens class #74
      cartilage explants #74
      genetic disease models #75
      inbred dba receptors #75
      diabetes arthritis #75
      effects development #75
      oestradiol #75
      cell reactivity #75
      acpapositive #75
      dth mice #75
      type collagens #76
      rat splenocytes #76
      peptide mhc #76
      anti carbamylated #76
      disease rheumatoid arthritis #76
      pain inflammation #77
      cyp7a1 #77
      lpr mrl #77
      inbred mouse strains #77
      new animal model #77
      collagen chains #77
      cell deficient #77
      rt1n #77
      regulatory vaccines #77
      rats eae #77
      oligomeric #77
      eae induced #77
      development insulitis #77
      nerve conduction velocity #77
      autoantigenic #78
      pathogenesis rheumatoid arthritis #78
      clinical arthritis #78
      rats respiratory #78
      mhc expression #78
      cartilage integrity #78
      pythons #78
      1ii #79
      mononuclear lung #79
      susceptibility disease #79
      inflammatory autoimmune #79
      autoimmune experimental epitopes #79
      shared epitope #79
      erosive arthritis #80
      chromosome study #80
      oxidases #80
      detection autoantibodies #80
      hnrnpa2 #81
      class antigen expression #81
      mhcii expression #81
      mog mbp #81
      sex linkage #81
      dr1 antigen #81
      inflammatory phase #81
      aspartic acid position #81
      spleen study #81
      induced leukocyte #81
      estrogen suppression #81
      mrl mp #81
      arthritis cells #81
      expression ll37 #81
      type macrophages #81
      14weeks #82
      pannus formation #82
      nadphoxidase #82
      drug encephalomyelitis #83
      bcg infection #83
      mice igg #83
      tlymphocyte genes #83
      cell independent #83
      expression mhc #83
      multiple sclerosis evidence #84
      naïve cells #84
      arthritis day #84
      strains animals #84
      reactive cells #84
      epidermal cells #84
      rat cardiac allografts #84
      spontaneous development #84
      inflammation joints #85
      knockout receptors #85
      cells recognize #85
      inflammation joint #85
      class molecule #85
      homopentamer #85
      antiifngamma #85
      anti cd4 #86
      animal humans #86
      severe eae #86
      classical humans #86
      mutant strains #86
      monoclonal antibodies mab #86
      gfoger #86
      phagocyte nadph #86
      preclinical stage #86
      contribution genes #86
      mhc class gene #87
      inbred rat strains #87
      alpha1acid glycoprotein #87
      estrogen induced #87
      smash #87
      thps #88
      fine specificities #88
      narac #88
      levels anti #88
      copy variation #88
      inguinal lymph nodes #88
      experimental autoimmune #89
      peptide immunization #89
      arthritic #89
      mice antibodies #89
      depletion cd8 cells #89
      genetic quantitative #89
      mabs mab #89
      mediated mechanisms #90
      adjuvant arthritis #90
      rheumatoid arthritis cells #90
      ilc2 activation #90
      autoimmune inbred c57bl #90
      susceptible #90
      genistein treatment #90
      pineal hormone melatonin #90
      arthritis compared #90
      monkeys mice #90
      histological sections #91
      synovial fluid serum #91
      cells apc #91
      activation cd4 cells #91
      protein induced #91
      cattle collagen #91
      backgroundan #91
      experimental mouse models #92
      abdominal region #92
      nod mhc #92
      anticitrullinated protein #92
      humans immunodominant #92
      difco #92
      mice melatonin #93
      xor #93
      animals autoantibodies #93
      natural polymorphisms #93
      290 patients #93
      cellspecific #93
      knockout myelin #93
      activated cells cells #94
      fcγrs #94
      macrophages development #94
      galactosylated #94
      autosomal genes #94
      endosomal acidification #94
      moderateintensity exercise #95
      induced sarcoma #95
      binding integrins #95
      chronic phase disease #95
      data rats #96
      cell alpha #96
      pregnancy disease #96
      macrophages stimulation #96
      nonglycosylated #96
      ifnbeta #96
      romani #96
      lung emphysema #96
      messenger tolllike receptor #96
      fetal rejection #96
      antiimmunoglobulin #97
      rheumatoid lymphocytes #97
      macrophages fibroblasts #97
      cathelicidins #97
      genetic female genes #97
      il33r #97
      hydroxylysine #97
      citrullinated fibrinogen #97
      complex mice #97
      acpa igg #98
      autoimmune experimental #98
      rheumatoid cartilage #98
      autoimmune rats #98
      ean #98
      swr mice #98
      collagen cytokines #99
      alternative pathways #99
      interleukin‐4 #99
      rat chromosomes #99
      tap2 #100
      ccp anti #100
      cultured crosses #100
      rats monoclonal antibodies #100
      protein antibody #100
      invading pathogens #100
      peptides cells #100
      thy1 antigens #100
      inducer animals #100
      tlymphocyte immunity #100
      eira #101
      diarthrodial #101
      cell determinants #101
      singlenucleotide polymorphism #101
      susceptible strain #101
      fprs #101
      safety drugs #101
      bone degradation #101
      findings treatment #102
      mouse monoclonal antibodies #102
      eae animal encephalomyelitis #102
      candidate autoantigen #102
      brucei infection #102
      oxidative burst #103
      agalactosyl #103
      ros homeostasis #103
      pathogenesis emphysema #103
      hla dr1 #103
      drb10401 #103
      mhcii #104
      male mice mice #104
      arthritic disease #104
      haplotypes histocompatibility #104
      synchrotron infrared #104
      f1 males #104
      skg mice #104
      nonarthritic #104
      mutation mice #104
      thelper cells #104
      fcγr #105
      osteoclasts mice #105
      type 22 #105
      vivo macrophages #105
      development antibodies #105
      autoreactivity #105
      hybridoma cell #105
      dmaam #105
      limited cross #106
      primed cells #106
      arthritis hla #106
      tcell immunity #106
      273 #106
      disease dose #106
      proteoglycan loss #106
      c3h mice #107
      cells synovial #107
      nzb mice #107
      development autoimmune disease #108
      fpr #108
      study tolerance #108
      littermates #108
      type hypersensitivity #109
      monoclonal igg #109
      delayedtype hypersensitivity #109
      enthesophytes #109
      reactive cell #109
      citrullinated proteins #109
      autoantibodies autoantigens #109
      presentation cells #109
      structural polymorphism #109
      carcinoma tumors #110
      autoimmune encephalomyelitis #110
      toxic shock syndrome #111
      experimental female #111
      cartilage #111
      inbred dba microscopy #111
      dba 1j mice #111
      backcross #111
      mog eae #111
      streptococcal cell wall #111
      female hypersensitivity #111
      humoral autoimmunity #112
      alphabeta receptors antigen #112
      presymptomatic individuals #112
      anti idiotypic antibodies #112
      extensive literature search #112
      amide bond #112
      trait loci #113
      tcra #113
      db1 #113
      mice collageninduced arthritis #113
      restricted cell #113
      adjuvant properties #113
      xid mice #113
      autoimmune c57bl mice #113
      oligoclonality #113
      ifngammaproducing cells #114
      adjuvantinduced arthritis #114
      rats collagen #115
      anti mcv #115
      mice disease #115
      drb10402 #115
      autoantigens autoimmunity #115
      proinflammatory cytokine #115
      susceptibility eae #116
      experimental epitopes #116
      pathogenesis autoimmune diseases #116
      lutz #116
      immunosorbents #116
      glycopeptides #116
      lymphocyte female #116
      ccp patients #116
      transgenic peptides receptors #116
      glyco #116
      antiarthritic #117
      congenic lines #117
      mice type #117
      tolerance induced #117
      encephalomyelitis autoimmune #117
      fluorescence nf #117
      antibodies reactive #117
      class expression #118
      samples individuals #118
      α enolase #118
      psoriasiform dermatitis #118
      myelin oligodendrocyte #118
      rats immunized #118
      alpha1acid #118
      pineal hormone #118
      05m #119
      rheumatoid arthritis review #119
      cd4 tcells #119
      radiological damage #119
      psa rheumatoid arthritis #119
      response cells #119
      neutrophils nets #120
      protein mbp #120
      experimental animal models #121
      chondrocyte cultures #121
      vivo animal models #121
      acpa negative #122
      treatment progesterone #122
      immune complex deposition #122
      genes age #122
      t‐lymphocyte #122
      transgenic neurons receptors #122
      pharmacological potential #122
      transfer arthritis #122
      patients acpa #122
      alphabeta cells #123
      c5b #123
      cell monoclonal #123
      symptoms associations #123
      nox2 activation #123
      type cytokines #123
      cartilage surface #124
      inbred mouse #124
      tlr4 stimulation #124
      oxidases neutrophils #125
      genetic rats #125
      blocking antigens #125
      allelic variations #125
      preimmunized #125
      immunodominant peptide #125
      cryogel #125
      general mechanisms #125
      disease mechanisms #125
      helperinducer #125
      qtl genes #125
      nzb nzw #126
      pnipaam #126
      nonobese diabetic #126
      female immunization #126
      cyclic polymorphism #126
      animal enzyme #127
      knockout murine #127
      atp8 #127
      absence cells #127
      microarray detection #127
      chronic inflammatory disease #128
      deiminases #128
      anticitrullinated peptide #128
      lining layer #128
      dominant epitope #128
      rats patients #129
      spleen rats #129
      bxsb #129
      multiple epitopes #129
      nos2 #130
      cells eae #130
      psd1 #130
      disease induced #130
      oestradiol testosterone #130
      vivo absence #130
      onset arthritis #131
      lipomannan #131
      epitope specific #131
      pronociceptive #132
      linomide #132
      intercross #132
      mineral oils #132
      kgf #132
      induction regulatory cells #132
      disease cgd #132
      leukosialin #133
      reduced severity #133
      ggaa #133
      rat chromosome #133
      myocellular #134
      knockout receptors antigen #134
      species animals #134
      mice estrogen #134
      patients cytokines #134
      accentuate #134
      interstitial collagens #134
      plasma synovial fluid #134
      eae #134
      peptides cyclic #135
      igg immune complexes #135
      spinal glial #135
      macrophages dendritic #136
      intracellular reactive #136
      chronic autoimmune disease #136
      immunizing #136
      receptor upregulation #137
      innate lymphocytes #137
      stimulated muscle #137
      immunopathological #137
      mice deficient #138
      ditiocarb #138
      immunomodulatory drug #139
      autoimmune mice #139
      control development #139
      dmannitol #139
      tcrdelta #140
      oligoclonal expansion #141
      thermoresponsive polymer #141
      producing cell #141
      gamma lymphocyte #142
      interferon‐γ #142
      or113 #142
      single subcutaneous injection #142
      genetic factors development #142
      phadia #142
      smfish #142
      rejection tolerance #142
      phosphate isomerase #143
      class haplotypes #143
      mice beta #143
      tcell alphabeta receptors #143
      cell hybridoma #143
      mhc haplotypes #144
      rheumatoid arthritis #144
      rat strains #144
      synovial hyperplasia #144
      syngenic #145
      severe chronic #145
      lyme arthritis #145
      tnf production #145
      tcr gamma delta #145
      treatment ici #145
      inbred buf rats #145
      rats induced #146
      neonatal growth #146
      function cells #147
      cellular heterogeneity #147
      ccp antibodies #147
      pregnancy levels #147
      systemic challenge #147
      gammainterferon #147
      phagocyte nadph oxidase #148
      α2i #148
      autoimmune disease #148
      cell surface antigen #148
      interestingly #148
      redox regulation #148
      human autoimmune diseases #149
      complex diseases #149
      drb104 #150
      mhc binding #150
      larsen score #150
      humans hybridomas #151
      levels antibodies #151
      receptor rats #151
      differential gene expression #151
      mice animals #151
      epicutaneously #151
      alphabeta receptors #152
      arthritic animals #153
      levels pregnancy #153
      key player #153
      pepsin #153
      mononuclear cells #153
      selfpeptides #154
      joint inflammation #154
      male rats rats #154
      daf1 #154
      fcgammar #154
      immune priming #154
      expression class #154
      critical event #154
      c4bbinding protein #154
      arthritis rheumatoid #155
      f1 mice #155
      autoantibodies autoimmune #155
      mace acs #155
      padi4 #155
      infiltrating cells #155
      serum synovial fluid #155
      specificities #156
      suppressive role #156
      mhc region #156
      stabilin1 #156
      murine keratinocytes #157
      adjuvanticity #157
      downstream signals #157
      genetic diabetes mellitus #158
      parentals #158
      analysis structure #158
      hypersensitivity reaction #158
      consensus motif #159
      meaib #159
      animals autoimmunity #159
      inbred c3h mice #159
      arthritis infectious #159
      systemic mice mice #159
      nursed #161
      day onset #161
      gamma interferon #161
      specific autoimmunity #161
      factors anti #161
      knockout severity #161
      benzylated #161
      anti ccp #162
      rheumatoid autoantigens #162
      βarrestin recruitment #162
      psors1 #162
      epitope #162
      arthritis inflammation #162
      binding collagen #162
      cd152 #162
      laboratory rats #163
      chains humans #163
      mouse type #163
      onset disease #163
      agalactosyl igg #164
      mrl #164
      striking similarities #164
      rats induction #164
      progesterone effects #164
      genes qtl #164
      autoantibody responses #164
      endobetanacetylglucosaminidase #164
      cells macrophages #165
      animal humans immunity #165
      nonimmunized #166
      tolerance induction #166
      pathogenic pathways #166
      melatonin mice mice #166
      epitope alleles #166
      class mice #167
      human autoimmunity #167
      ag7 #167
      tlymphocyte humans #167
      nox2 #167
      seronegative #167
      phase disease #168
      genetic backgrounds #168
      cd1 #168
      mice cd4 cells #168
      acpa levels #169
      p12 #169
      oxazole #169
      denoted #169
      pathogenesis arthritis #170
      cryogels #170
      joints male #170
      lymph node cells #170
      mirp #170
      inherited disorder #170
      experimental animal #170
      ros nitric oxide #171
      encephalomyelitis eae #171
      oxazolone #171
      peripheral lymphoid organs #172
      rat placenta #172
      single nucleotide polymorphism #172
      lst1 #172
      autoimmune eae #172
      rheumatoid #172
      autoimmunity cell #172
      monoclonal autoantibodies #173
      inbred dba models #173
      sod3 #173
      resistant rats #174
      nasal cartilage #174
      studies pain #174
      presence autoantibodies #174
      class gene #174
      mice mutation #175
      ifn signature #175
      understanding pathogenesis #175
      maternal decidua #175
      new mouse model #176
      skin disease #176
      mammalian crosses #176
      tryptophan catabolism #176
      secondary challenge #176
      moab #176
      strains molecular #176
      lymphotoxinα #177
      ctla‐4 #178
      hladrb1 alleles #178
      histocompatibility #178
      alternative pathway complement #179
      immunized #179
      protein anti #179
      dextran sulphate sodium #179
      nod genes #179
      mice role #179
      epitopes female #180
      complex disease #180
      arthritis methods #180
      cgd patients #180
      alleles arthritis #181
      molecular adaptations #181
      genetic influence #181
      autoimmunity disease #181
      arginine deiminases #182
      hormone melatonin #182
      immunoglobulin mice mice #185
      multistep process #186
      rats reactive #186
      cells lymph nodes #186
      antigen processing presentation #186
      drb1 chains #187
      dba #187
      b10 #187
      tcell recognition #187
      chondritis #188
      substrains #188
      molecular peptide #188
      mtec #189
      cells disease #189
      synovial membranes #190
      inflamed joint #190
      positionally #190
      hnrnpa2b1 #190
      oligodendrocyte glycoprotein #191
      ly1 #192
      autoantibody profiles #192
      cross‐reactivity #192
      fmlf #193
      passive mice mice #193
      cyclic predictive #194
      glycoprotein peptide #194
      proteins myelin #194
      chapter 16 #195
      mice mutant #195
      mhv #195
      perpetuate #195
      oophorectomized #196
      lewis rat #196
      mhc class expression #196
      tcell response #196
      myelin glycoprotein #196
      acutephase response #197
      pannus #197
      evidence development #197
      multiplex assay #197
      early appearance #198
      swedish patients #198
      igmrf #198
      genetic links #198
      dr4 antigen #199
      rat genome #199
      interleukin17 #199
      hla association #200
      citrullinated peptide #200
      cell collagen #200
      pathogenesis autoimmune #201
      acpa status #202
      myelin proteolipid protein #202
      myelin proteins myelin #202
      dendritic cells macrophages #202
      instigation #202
      complete elimination #203
      mice cells #203
      immunization immunoglobulin #204
      2 complex #204
      spleen staining #204
      class molecules #204
      dth response #205
      ides #205
      macrophages mice #205
      native collagen #205
      suppresses #205
      nonparametric tlymphocytes #205
      defb4 #206
      wild rats #206
      betaestradiol #206
      induced upregulation #207
      mice peptide #207
      insulitis diabetes #207
      desmoglein 3 #207
      interleukin4 mice mice #207
      noxs #207
      parental strains #207
      alternative complement pathway #207
      intranasal challenge #207
      immunization mice #208
      highest probability #208
      severity disease #208
      vivo patients #208
      antigen presenting #208
      naive mice #208
      immunoglobulin vh #209
      disease rheumatoid #209
      cotwins #209
      vav1 #210
      valuable tools #210
      specific antibodies #210
      susceptible strains #210
      citrullinated vimentin #210
      highfatdiet #210
      hla dr4 #211
      purified protein derivative #211
      natural antibodies #211
      diseases genetic #211
      glucose6 phosphate #211
      association rheumatoid arthritis #212
      cells immobilized #212
      large numbers #212
      psoriasiform #213
      antibody binding #213
      mice injected #213
      tsst1 #214
      triethylsilane #215
      inbred rat #215
      cytofluorometric #215
      antigen induced #215
      central tolerance #215
      mhc class antigens #215
      dissect #216
      training hiit #216
      lower level #216
      rats immunization #217
      lentiviral vector #217
      cd23 #217
      induced autoimmune #217
      inflammatory infiltrates #217
      joints mice #217
      resistant strain #217
      treatment onset #218
      antigen tcell #218
      peptide antibodies #219
      k8 #219
      granuloma formation #219
      fcrγ #219
      autoimmunity #219
      cells autoimmune #220
      bone erosions #220
      hyl #220
      peptidylarginine deiminases #220
      cyclosporin treatment #221
      redox signaling #221
      fine specificity #221
      cells dendritic #221
      rheumatoid factor #221
      agouti rats #221
      targeted deletion #221
      pinealectomy #221
      wkymvm #222
      cybb #222
      monoclonal antigens differentiation #222
      cartilage damage #222
      thymectomized #222
      multiplex #223
      igg2a #223
      experimental autoimmune neuritis #223
      carbamylated #223
      inflammation vivo #224
      expressing #224
      cells antigen #225
      clinical scoring #225
      established disease #225
      interleukin‐10 #225
      lew #225
      pathogenic antibodies #226
      disease locus #226
      j1 #227
      macrophagelike cells #227
      arthritis objective #228
      presenting cells #228
      delayed type hypersensitivity #228
      presence anti #229
      cell selection #229
      site inflammation #230
      eae rats #230
      ls1 #231
      human rheumatoid #231
      reactive oxygen #232
      monoclonal immunohistochemistry #232
      ameliorated #233
      role eosinophils #233
      synovial joints #233
      lack expression #233
      production ros #233
      centimorgan #234
      lower numbers #234
      mhc gene #235
      chromosome 14 #235
      chronic psychosocial stress #235
      staphylococcal infection #235
      immune complex #236
      specificity animals #236
      pathological mechanisms #237
      control strain #237
      autoimmune chronic #238
      progression arthritis #238
      c5 #239
      trait locus #239
      inbred dba tlymphocytes #240
      study plasma #241
      strong influence #242
      joint pain #242
      class genetic #243
      monoclonal antigen #243
      hla drb1 #243
      multicomponent #243
      positive anti #243
      protected #243
      treatment autoimmune #244
      crosses #244
      common denominator #244
      cutaneous infection #244
      estrus cycle #244
      inflammation cartilage #244
      binding antibodies #245
      allelic differences #246
      development emphysema #246
      rt1l #246
      antibodies anti #247
      new model #247
      florescence #247
      normal cartilage #247
      antibody response #247
      inbred strain #247
      efficient expression #248
      activity assays #248
      induced chronic #249
      oxygen species #249
      picryl #250
      mouse rat #250
      arthritic joints #250
      fragments rats #250
      node cells #250
      inflammation score #250
      hyperinflammation #251
      conditional knockout mice #251
      develops #251
      nadph oxidase #251
      treatment rats #251
      mice lack #252
      dark agouti #252
      mice lymphocytes #252
      response disease #252
      role model #252
      lpr mice #254
      cartilage matrix #254
      onset clinical #254
      lacking #254
      proteins glycoproteins #254
      dinitrofluorobenzene #254
      class mhc #254
      inbred c3h #255
      autoimmune response #255
      anti arthritic #256
      specific subgroups #256
      postmenopausal bone #256
      specific neutralizing #256
      inflammatory disorder #256
      disease cell #257
      additive interaction #258
      class mhc molecules #259
      mir144 #260
      relationship immunologic #260
      chronic granulomatous #260
      mediated suppression #261
      secondary osteoporosis #261
      denatured #261
      lymphocytes helper #261
      autoimmune neuritis #261
      mice expressing #261
      immunologic animals #262
      selfantigen #263
      tolerance mice #265
      genetic techniques #265
      primary immunization #265
      pregnancy mice #265
      mouse strain #265
      crossreactive #265
      cysteine proteases #267
      rats animals #267
      antigen specific #267
      vim2 #267
      posttranslational modifications #268
      xid #268
      lentiviral gene #268
      pathogenic roles #269
      mann whitney #269
      complement c5 #270
      oxpl #270
      monosodium urate crystals #271
      selfantigens #271
      melatonin effects #271
      castrated #271
      amino acid transporters #273
      experimental model #273
      lewis rats #274
      hdac1 #275
      tcells #275
      inhibitory peptide #275
      synovial lining #275
      nasally #275
      macrophages dendritic cells #276
      fcgr3b #276
      viral female hepatitis #277
      deiminase type #277
      rheumatoid arthritis association #277
      producing cells #277
      metabolic properties #278
      recognize #278
      gp70 #279
      colon length #279
      interferongamma #279
      induced tolerance #280
      dinucleotide phosphate #280
      immunological receptors antigen #281
      neonatal mice #281
      recipient mice #281
      inflammatory conditions #281
      passive transfer #281
      hemiacetal #282
      isoflavone genistein #283
      factor production #283
      inbred nod #283
      disease susceptibility #283
      igg2b #283
      increased serum levels #284
      helper inducer #284
      aire #284
      severe colitis #284
      idiotope #285
      aureus strain #285
      complete protection #285
      maintained #285
      publication animals antibodies #285
      endophilin #285
      theilovirus #285
      emulsified #286
      hla dr2 #287
      antibody production #288
      melatonin mice #288
      tlr9 mice #288
      melatonin release #288
      myelin basic protein #288
      mice immunized #289
      cells autoimmunity #289
      synovial cells #291
      ctla4 expression #291
      disease cells #291
      autoimmune mechanisms #292
      rheumatic conditions #292
      cytokines disease #293
      induced ros #293
      collagen receptors #293
      increased copy #293
      mouse genes #294
      unique model #294
      antigen processing #295
      gastric parietal #295
      c3h #295
      c57bl 6 mice #295
      nerve conduction #296
      6week #296
      immunological receptors #296
      tissue‐specific #296
      dnfb #297
      phosphopyruvate #297
      murine dendritic cells #297
      helical peptides #297
      vivo imaging #298
      ppad #298
      cd19 cells #298
      gene selection #298
      transplantation antigens #299
      citrullination #299
      solidphase synthesis #299
      tcr beta #300
      posttranslational rats #301
      neutrophil extracellular traps #301
      alphabeta #302
      peptide antibody #302
      draining lymph #302
      extraembryonic tissues #302
      animals antibodies #303
      epidemiological investigation #303
      1 interferon #303
      pathogeneses #303
      strains mice #303
      autoimmune diseases #304
      igg glycosylation #304
      cgd #304
      conditioned disease models #304
      mutant strains mice #305
      cells tcr #305
      cartilage development #305
      immunological function #305
      immunological studies #306
      murine colitis #306
      αgalcer #306
      gammaifn #306
      hcdr3 #306
      class histocompatibility #307
      inpp4b #307
      immunisation #307
      basal metabolic rate #308
      basal metabolic #309
      chromosome 10 #309
      articular cattle cells #310
      arthritis study #310
      perpetuation #311
      multiple sclerosis eae #311
      synthetic peptide #312
      alleles animals #312
      disease symptoms #312
      inflamed joints #312
      c3bi #313
      exuberant #313
      epitopes #313
      induced colitis #314
      activatory #314
      r620w #315
      mice genes #315
      intradermally #315
      trypanosoma brucei brucei #316
      onset rheumatoid #318
      classical risk factors #318
      tubule cells #319
      genetic interactions #319
      galactosyl #319
      genomewide linkage analysis #320
      deiminase #320
      mice subjected #320
      spleen bone marrow #320
      cells specific #323
      il21r #323
      impact disease #324
      daf2 #324
      ccp1 #324
      expressing human #324
      expression cells #325
      specific cell #325
      rat gene #325
      surprisingly #326
      resembles #327
      mgps #327
      c57bl mice #328
      allelic variant #328
      immunoenzyme #329
      publication adjuvants #329
      constant light #329
      complex genes #330
      early arthritis #331
      glycoprotein mog #332
      fcgammariia #332
      rheumatoid synovial #332
      nucleotide polymorphism #332
      anticcp #333
      mouse hepatitis virus #333
      35ssulfate #334
      joint tissues #335
      mrl lpr mice #335
      susceptibility genes #335
      autoimmune inflammation #336
      cell response #338
      epitope specificity #340
      cells spleen #340
      delayed onset #340
      ros oxygen species #341
      activation macrophages #341
      adjuvants immunologic #341
      rat #341
      erosive #341
      specific autoimmune #342
      6weeks #342
      animal enzyme inhibitors #342
      incident cardiovascular events #342
      drb1 alleles #343
      diabetic mouse #343
      sequence animals #343
      rats injection #343
      rapid spread #343
      182780 #344
      monoclonals #344
      favor #345
      acpa positivity #345
      energetic costs #346
      intraperitoneal injection #347
      pemphigus vulgaris pv #348
      complement activity #349
      reduced capacity #349
      neuritis #349
      igg autoantibodies #350
      phenotype rats #351
      methylcholanthrene #352
      thymic selection #352
      mice induction #353
      anti cyclic #353
      immunoregulation #353
      c3h hej #353
      mice cd4 #354
      arthritis synovial #354
      autoantigens autoimmune #354
      splenic macrophages #355
      dsg3 #357
      cells autoantibodies #358
      adjuvant activity #358
      tbetarii #358
      injected #359
      neuritogenic #359
      enos #359
      tcrbeta #360
      tlr3 #361
      pvg #361
      freund #361
      murine lupus #362
      hla transgenic #362
      allergic encephalomyelitis #363
      determines #363
      identification genes #363
      mouse chromosome #363
      generation ros #363
      hladr4 #364
      cells anti #364
      recognized #364
      immune deviation #366
      glycoproteins mice #366
      sex chromosomes #366
      european journal #366
      psychosocial stress #367
      antiidiotypic antibodies #367
      toxic shock #368
      loci #368
      100 micrograms #368
      ncf2 #368
      autoimmune responses #368
      affinity ligand #368
      histocompatibility antigens #369
      nasal administration #369
      pentameric #369
      increased production #370
      immune pathogenesis #370
      clinical onset #371
      regulate #371
      serum transfer #371
      newborn antibodies #372
      role mif #372
      alternative activation #373
      autoantigens #375
      rheumatoid cell #375
      acutephase proteins #376
      undifferentiated arthritis #376
      glucose6 #377
      gia #379
      reparixin #380
      mouse monoclonal antibody #381
      induced lupus #381
      oxidase deficiency #381
      fia #382
      fragments immunoglobulin #382
      granulomatous #383
      granulomatous disease #384
      c1a #384
      specific loci #384
      naive rats #384
      postmenopausal bone loss #385
      shock syndrome #385
      cell specificity #386
      pc4 #386
      ptpn22 gene #387
      filaggrin #387
      antioxid #387
      backcrosses #387
      phase response #388
      inbred nod receptors #388
      downregulating #389
      deficient #390
      ovulation rate #390
      greater 50 #390
      radiological progression #391
      anaphylatoxin c5a #391
      peptidylarginine #391
      finetune #392
      il4 il10 #394
      rf1 #394
      ameliorating #395
      draining #397
      autoantibody levels #397
      induced metabolic #397
      juvenile chronic arthritis #398
      immunized mice #399
      regulation animals #399
      protein myelin #399
      inflammatory reactions #400
      reactive oxygen species #400
      antibody formation #401
      genes cells #401
      inflammation demyelination #403
      immunopeptidome #403
      biacore #403
      beta chain #404
      fcγriib #404
      experimental #405
      basic protein #405
      n31 #407
      effects models #407
      rheumatoid case #407
      pam3csk4 #408
      immunogenetics #409
      major locus #409
      3hproline #410
      diabetes loci #410
      intracellular processing #410
      hladrb1 #412
      cd43 #412
      cell phenotypes #412
      titres #413
      susceptibility loci #413
      reproductive performance #414
      characteristic feature #414
      cultured collagen #415
      igk #415
      levels autoantibodies #416
      female mice #416
      synovial inflammation #417
      spontaneous mutation #417
      lupus mice #417
      genetically modified mice #418
      wtccc #419
      induced pain #419
      molecular interactions #419
      class hdacs #419
      hiit #420
      ameliorate #420
      tcell #421
      lower affinity #422
      dr4 #422
      lipidomic #423
      restricted #424
      subsets animals #424
      hyaline cartilage #425
      congenic strain #426
      inflammatory cells #426
      regulatory animals #426
      carbohydrate moiety #429
      postimmunization #430
      nonimmunogenic #430
      epitopes humans #430
      nod mouse #430
      immunoregulatory #431
      il10 mice #433
      patients healthy individuals #433
      cells antibodies #434
      spontaneous autoimmune #435
      factor 5 #435
      cells beta #436
      reactivities #436
      mass spectrometric analysis #437
      decalcified #437
      chromosomes chromosome #437
      crystallizable #437
      mice effects #438
      immunised #438
      specific antigens #438
      helperinducer tlymphocytes #438
      joint swelling #439
      cells #439
      nod #440
      wildtype mice #440
      vitro techniques leukocytes #441
      female immunoglobulin #441
      effector functions #441
      normal rats rats #441
      complete adjuvant #442
      mice activation #442
      patients population #442
      methylβcyclodextrin #443
      mhc class molecules #443
      tlr2 expression #444
      myelin basic #444
      genomewide scan #445
      mouse models #445
      systemic mice #445
      mice humans #445
      skeletal muscle function #445
      ros production #447
      control mice #448
      induced mice #448
      pain model #448
      inbred strains receptors #448
      synovial tissue #449
      tcell responses #449
      complement factor #449
      innate adaptive #450
      igg anti #451
      apcs #451
      hybridoma cells #452
      reduced production #452
      heterologous #452
      differs #454
      cells chronic #456
      lglutamine #456
      raloxifene #457
      inbred c57bl tlymphocytes #457
      rheumatoid cells #459
      eae cns #459
      resembling #459
      lung macrophages #459
      priming #459
      antibodies monoclonal #460
      256 #462
      autoantigen #462
      neutrophil functions #462
      gilt #463
      fab fragments #464
      autoantibody production #465
      salivary glands #466
      receptor tcr #466
      cells lymph #467
      titers #469
      earlier onset #469
      anticyclic citrullinated peptide #474
      arthritic rats #474
      disease mice #474
      antibody mediated #474
      cartilage cells #475
      human autoimmune #476
      cluster genes #477
      mice exhibited #477
      mediated inflammation #478
      therapeutic vaccination #478
      female hla #479
      apoptosis arthritis #479
      laboratory rat #479
      aggravated #480
      quantitative trait loci #480
      deacetylase 1 #480
      polymorphonuclear cells #482
      anti idiotypic #482
      immune reactions #484
      immunologists #485
      immunoglobulin male #486
      jca #487
      tcralpha #487
      oxyntic #487
      controlling #487
      invariant natural #488
      insulitis #488
      specific immune #488
      gland animals #489
      normal mice #490
      cytoplasmic calcium #494
      nacetylglucosaminidase #495
      early rheumatoid #496
      reactive nitrogen #496
      conclude #496
      gammadelta cells #496
      h2b #496
      mbp #498
      small effects #498
      receptor 9 #499
      biologicals #500
      autoreactive cd4 #503
      nadph #503
      immunoenzyme techniques #503
      pathogenic #506
      immunofluorescence analysis #507
      chondrocytes collagen #507
      mab mabs #508
      persistent pain #508
      mineral oil #508
      isopropyl #508
      gingipain #509
      orosomucoid #509
      immunization passive #509
      mhc class #510
      mice knockout mice #510
      c3h hej mice #511
      differential gene #511
      deficient mice #511
      812 #511
      systemic spread #511
      blymphocytes #512
      mrp8 #515
      behavioral alterations #517
      hydroxyquinolines #517
      antibody complex #518
      u1 #518
      suggestive linkage #519
      chronic granulomatous disease #519
      inflammation #519
      tcr recognition #520
      modified form #521
      pcorr #522
      ttg #522
      dextran sulfate sodium #522
      inflammation role #523
      data peptide #523
      litter size #524
      p47phox #524
      encephalitogenic #524
      neutrophil granulocytes #525
      mnc #526
      tconv #526
      mechanical hypersensitivity #526
      maternal antibodies #527
      disease acute #527
      spleen cells #527
      vaccinates #528
      larsen #528
      primed #528
      tolonium #528
      rat rats #529
      tolllike receptor tlr4 #529
      displayed #529
      ifa #529
      cell antibodies #530
      autoantibody #530
      antigen presentation #530
      pathogenesis sle #530
      isac #530
      ratg #531
      epistatic #532
      bred #532
      complex role #533
      lyt2 #533
      posttranslational receptors #534
      spleen lymphocytes #536
      resorptions #536
      translational modification #536
      urokinase #537
      synovial #537
      experimental rats #538
      cells inflammatory #538
      animals #538
      joints #540
      fibroblast synoviocytes #540
      antigen recognition #540
      suppressive #540
      membrane attack complex #541
      rheumatoid humans #543
      specific autoantibodies #544
      regulating #545
      protein tyrosine phosphatase #545
      hypomorphic #546
      tlymphocytes #547
      animal gene #547
      shortcut #547
      immunohistochemical methods #548
      entheses #548
      formyl peptide receptors #548
      mog #550
      immunoglobulin fab #552
      mixed lymphocyte reaction #553
      nox activity #554
      breeder #555
      cell epitopes #557
      stronger association #557
      beta animals #557
      cells control #558
      early onset #559
      healthy mice #560
      elispot assay #561
      transgenic molecular #562
      ptdins3p #563
      inbred strains #563
      negative selection #563
      neutrophil depletion #564
      deeper layers #565
      therapeutic treatment #565
      earlier #566
      target tissue #566
      immunoglobulin heavy chains #566
      darkness #566
      crucial #567
      interferon signature #568
      disease loci #568
      outbred #568
      mycobacteria #569
      cells pathogenesis #569
      neutrophilia #569
      concomitantly #570
      mice compared #571
      btla #572
      transgenic mouse models #572
      keratin8 #573
      col2 #574
      presenting #576
      pepstatins #576
      estrogen treatment #577
      terpenes #577
      keratinocyte growth factor #578
      prolactin prl #578
      ptm #579
      sera patients #579
      triple helix #580
      f1 hybrids #581
      methotrexate mice #581
      production ifngamma #583
      hybridoma #583
      inflammatory joint #583
      exaggerated #584
      time onset #584
      lymphocyte antigens #584
      antibody reactions #585
      traps nets #590
      antigen antibody #591
      environmental triggers #591
      immunological tolerance #592
      lxrα #592
      oligoclonal #592
      transgenic models #593
      noncollagenous #593
      macrophages #594
      autoimmune disorders #594
      adaptive immunity #594
      clonal expansion #595
      multiplexing #595
      th1 cytokines #595
      xanthine oxidoreductase #596
      tcell activation #599
      cells study #599
      develop #600
      th2 cytokines #602
      augmented #602
      n85 #602
      spite #602
      common diseases #603
      pemphigus vulgaris #603
      mouse monoclonal #603
      phagosomal #604
      cells male #604
      cells involved #604
      oxa #606
      mice inbred #606
      animal rats #606
      class humans #607
      genotype hla #608
      frozen sections #608
      spleen animals #609
      inefficiently #610
      regulatory role #610
      production ifn #611
      naive #611
      positive individuals #612
      quantitative trait locus #615
      th1 type #616
      acetophenones #616
      mutant strains receptors #616
      alpha chains #616
      class antigens #616
      idiotypic #616
      autoantibodies #616
      exponential phase #616
      oral immunization #617
      nonobese #617
      beta type #618
      day mice #619
      wistar restraint #620
      promiscuous #620
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      staphylococcal infections #1736
      sicca #1737
      phagocytic #1737
      fmoc #1739
      intranasally #1740
      arthritis patients #1742
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      prophylactic treatment #1744
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      new loci #1749
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      neoplastic disease models #1753
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      infiltrating #1762
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      dr2 #1766
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      higher frequency #1770
      triggering #1770
      multiple genes #1770
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      peptide antigens #1775
      operate #1776
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      adoptively #1782
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      local administration #1788
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      compartmentalized #1791
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      dogma #1794
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      immune recognition #1800
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      rechallenge #1803
      peyer #1804
      obese diabetic #1805
      aureus infection #1808
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      elucidation #1811
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      recovery phase #1814
      nonfunctional #1817
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      cd8 lymphocytes #1856
      macrophages neutrophils #1856
      humoral #1857
      rac2 #1858
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      lacrimal apparatus #1865
      rats groups #1871
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      immunoadsorption #1873
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      carries #1875
      major #1876
      subsequent development #1879
      cartilages #1879
      candidate #1883
      antigen humans #1890
      inflammation lung #1892
      polyclonal #1893
      bacterial clearance #1894
      ovalbumin #1897
      cyanogen #1900
      striking #1902
      tcr repertoire #1903
      lymphatics #1903
      indicating #1905
      complexity #1905
      proteins rats #1907
      model rats #1908
      gammadelta #1910
      mediated #1910
      enzyme linked #1911
      cell maturation #1912
      cells neutrophils #1912
      interferon gamma #1914
      chromosome #1916
      erythematosus sle #1916
      totally #1918
      6 hours #1920
      cartilage tissue #1923
      721 #1924
      anti #1924
      gαq #1926
      pronounced #1927
      ears #1929
      isoantigens #1931
      bcell receptors #1933
      expression cytokines #1934
      trypanosoma brucei #1937
      animals lymphocytes #1937
      sialyltransferases #1939
      mice receptors #1940
      antigen tcell receptors #1944
      type plasminogen #1945
      predisposition #1949
      prevented #1950
      subclasses #1950
      constituting #1955
      cardiac allografts #1956
      snakes #1957
      perforin #1957
      agp #1959
      mmc #1962
      iga igg #1967
      levels serum #1967
      pinocytosis #1967
      edition #1967
      possibilities #1969
      fcγ receptor #1969
      strong #1971
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      react #1975
      mip #1977
      stimulations #1978
      synovial tissues #1979
      carp #1979
      ova #1980
      inbred cba #1980
      cd154 #1982
      pregnant rats #1983
      cell clone #1985
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      milder #1988
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      mast cell #1999
      cd18 #2000
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      microglia activation #2002
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      contact dermatitis #2008
      reverted #2008
      prototypic #2011
      abca1 #2016
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      barré syndrome #2018
      knockout #2020
      tissue inflammation #2021
      immunoglobulin #2023
      genes #2025
      cell #2027
      mabs #2028
      cytokine secretion #2028
      demyelination #2030
      chord #2031
      tetramers #2032
      c5ar #2033
      mesenteric lymph #2035
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      beta gene #2035
      4 tlr4 #2041
      factor mif #2041
      mab #2042
      diethyldithiocarbamate #2043
      immunomodulatory properties #2044
      sex chromosome #2045
      cell immunity #2047
      hypergammaglobulinemia #2050
      oestrogens #2050
      castration #2053
      cell function #2053
      species signal #2053
      coinciding #2055
      emphysema #2056
      glycosylation humans #2057
      innate inflammation #2058
      increased frequency #2058
      dramatically #2059
      activation complement #2061
      vitro vivo #2061
      accompanied #2067
      genetic differences #2068
      dominant #2070
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      hyaluronoglucosaminidase #2072
      mdsc #2076
      mature cells #2077
      polyradiculoneuropathy #2077
      respiratory tract #2079
      lysine residues #2080
      antiphospholipid syndrome #2081
      cell depletion #2082
      mice pregnancy #2083
      complement #2094
      methotrexate mtx #2094
      conditional deletion #2095
      lysine #2096
      addressed #2097
      αβ #2100
      bioreactor #2100
      suggested #2102
      evokes #2103
      led #2103
      antigens hla #2104
      patients rheumatoid arthritis #2105
      human chondrocytes #2110
      nose #2117
      lentiviral vectors #2120
      pulmonary inflammation #2122
      glycan #2122
      immune functions #2126
      pad4 #2127
      oxidants #2129
      total igg #2130
      secondary receptors #2133
      inducing #2136
      occurring #2139
      histopathological #2140
      selective estrogen #2141
      target tissues #2141
      dissection #2142
      plasminogen #2143
      transduction lymphocytes #2145
      extracellular calcium #2146
      subphenotypes #2146
      bound #2147
      h2d #2147
      circulating monocytes #2149
      immunohistochemical analysis #2151
      129 strain mice #2151
      reality #2153
      clinical aspects #2157
      periphery #2161
      major histocompatibility complex #2162
      late stages #2165
      moabs #2165
      rheumatoid biomarkers #2165
      prone #2169
      entire #2174
      syringes #2176
      mimics #2177
      animal model #2179
      immune regulation #2180
      human leukocytes #2181
      psoriatic arthritis #2184
      dynorphins #2184
      dnp #2185
      native #2188
      injury ali #2200
      dss #2203
      lps stimulation #2204
      structural requirements #2211
      molecular pathways #2213
      confirming #2214
      12th #2215
      interleukin2 #2216
      therapeutic effects #2216
      activation cells #2217
      animal mice mice #2217
      naïve #2219
      galactose #2220
      regulates #2220
      suggesting #2221
      wt mice #2224
      immunoreactivity #2225
      mammalian #2232
      shrna #2232
      neutralized #2233
      governs #2233
      presentation #2234
      accelerates #2236
      reduced susceptibility #2239
      autoimmune conditions #2239
      ctla4 #2239
      lacked #2240
      graft rejection #2244
      inflammatory phenotype #2248
      cholera toxin #2248
      cell priming #2252
      exacerbated #2253
      monoclonal antibodies #2254
      cell receptors #2256
      tcell proliferation #2261
      sjögren #2263
      regulation immune #2265
      involved pathogenesis #2267
      hla #2269
      mph #2274
      progeny #2274
      immunospot #2278
      antigenic #2279
      murine #2279
      neutrophil apoptosis #2280
      mice treatment #2280
      lymph nodes #2281
      dependent #2284
      inflammatory #2288
      immunizations #2289
      homologous #2292
      plasmatic #2293
      determining #2296
      modified proteins #2296
      histological evaluation #2296
      cba mice #2297
      regulatory mechanisms #2299
      knockout mice #2300
      apocynin #2302
      segregating #2308
      infiltrating macrophages #2309
      presentation antigens #2310
      wounding #2312
      drastically #2315
      genetic basis #2315
      il10 #2317
      healthy donors #2318
      hydroxylation #2320
      barré #2320
      inflammatory mechanisms #2321
      sera #2325
      throughput nucleotide #2325
      p00002 #2326
      antigens histocompatibility #2328
      wild #2329
      cells induced #2331
      demyelinating disease #2336
      n24 #2338
      lewis #2345
      gk #2347
      reciprocal #2353
      receptor α #2353
      ethylenes #2358
      specific igg #2358
      illness stress #2361
      monosaccharide #2363
      hyaline #2364
      biological agents #2365
      lectins type #2366
      acrylamides #2366
      sex hormone #2366
      degradative #2367
      phosphoproteins #2369
      eliminated #2374
      wf #2374
      immunogens #2375
      peptides derived #2375
      lymphotoxin #2375
      genetic selection #2376
      treatment rheumatoid arthritis #2376
      cxcl1 #2382
      amps #2382
      antinociceptive #2383
      nonalcoholic steatohepatitis #2384
      mouse model #2386
      contaminating #2386
      phenotypes #2391
      sidechain #2391
      receptor transforming #2392
      knock #2394
      syngeneic #2394
      septic arthritis #2396
      systemic lupus erythematosus #2397
      hla genes #2398
      p38 mapk #2400
      inflammatory reaction #2400
      serum autoantibodies #2408
      increased incidence #2409
      mice models #2411
      equina #2413
      intraperitoneal injections #2418
      genetic receptors #2420
      genetic studies #2420
      structure analysis #2423
      realtime pcr #2424
      mice expression #2426
      tlr2 tlr4 #2429
      acute phase #2430
      suggestive evidence #2430
      lentivirus #2430
      unmodified #2431
      cytokines chemokines #2432
      collagen fibrils #2432
      cko #2432
      lymphocytes cd4 #2432
      cells antigens #2434
      agents arthritis #2440
      early phases #2440
      inflammatory activity #2442
      mice multiple #2446
      genetic predisposition #2449
      receptors complement #2450
      b6 #2450
      551 #2451
      lipoxin #2458
      inflammatory demyelinating #2459
      animal disease models #2463
      exemplified #2466
      idiotype #2468
      antibody responses #2469
      strains #2471
      animals cd4 #2473
      administration intranasal #2473
      axotomy #2477
      translational modifications #2477
      additively #2477
      quantitative #2480
      class #2480
      regulatory #2487
      animal experiments #2492
      specific #2493
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      cystatin #2504
      mhc class genes #2505
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      transgenic microscopy #2512
      bystander #2515
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      ppd #2518
      chemokines cytokines #2519
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      treatment rheumatoid #2524
      hyperostosis #2525
      amiloride #2526
      nod mice #2527
      microsatellite markers #2534
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      infiltration #2541
      resemblance #2542
      undertaken #2545
      postmenopausal osteoporosis #2546
      proteolipid #2552
      dapsone #2560
      similarities #2561
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      kynurenine #2563
      plp #2563
      deprotection #2564
      nox #2566
      succeeded #2567
      transferring #2573
      fine #2573
      passive #2574
      dying cells #2575
      rp patients #2575
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      quantitative traits #2577
      complementarity #2580
      peptides #2585
      chick #2589
      calgranulin #2590
      peritoneal macrophages #2591
      antibody levels #2591
      misinterpretation #2593
      interferon type #2595
      sex hormones #2597
      fibrinolysin #2598
      onset #2603
      antiinflammatory properties #2603
      unlinked #2605
      zymosan #2610
      induction #2611
      postulated #2614
      exert #2615
      antimicrobial peptides #2618
      surprising #2621
      interferon beta #2623
      proteolipid protein #2632
      ifn α #2634
      single chain #2639
      sialoglycoproteins #2643
      plasmin #2647
      unable #2649
      asparagine #2651
      tlr9 #2653
      antigens #2656
      disease genotype #2658
      hla antigens #2659
      antinuclear #2663
      submandibular gland #2663
      functional impact #2663
      eluted #2666
      osteonectin #2667
      invading #2670
      brucei #2670
      n22 #2670
      microliters #2671
      biological pathways #2673
      bordetella #2680
      ease #2683
      new therapeutic strategies #2683
      leukocyte antigen #2688
      th1 #2690
      acd #2696
      day treatment #2697
      allelic #2697
      igg3 #2698
      genetic variations #2698
      animal encephalomyelitis #2702
      neutrophils macrophages #2703
      gamma mice #2711
      peptides protein #2714
      γδ #2716
      treatment mice #2717
      rat model #2718
      human complement #2725
      patients anti #2727
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      biased #2730
      ifngamma #2730
      lymphocyte subsets #2730
      post partum #2731
      lamina propria #2735
      fumigatus #2735
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      fragment #2743
      vav #2743
      mice exposed #2750
      leucocyte #2754
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      bromocriptine #2768
      transgenic mouse #2772
      depleting #2773
      human leukocyte #2774
      tyrosine phosphatase #2774
      cytolysis #2777
      qtls #2777
      strong evidence #2777
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      enigmatic #2780
      iga igm #2780
      genetically #2782
      finemapping #2785
      explanation #2785
      treated rats #2786
      alcoholic steatohepatitis #2786
      intraperitoneal #2787
      tolerogenic #2789
      bone cartilage #2790
      sjogren syndrome #2791
      inbred mrl #2798
      current review #2798
      animal encephalomyelitis autoimmune #2799
      hk #2801
      callithrix #2804
      spleen #2812
      261 #2813
      neuropathology #2817
      genistein #2819
      alpha #2821
      lack #2822
      activated macrophages #2825
      hyaluronidase #2830
      conventionally #2831
      narrowed #2832
      prl #2835
      olive oil #2838
      demyelinating diseases #2841
      resistant #2842
      hallmark #2843
      glucose uptake #2846
      beta receptor #2847
      beta tgf #2848
      bind #2848
      th1 response #2852
      demyelinating #2852
      polymorphonuclear leukocytes #2856
      phases #2858
      treg cell #2859
      dependent cell #2859
      interleukin receptors #2864
      antibodies antinuclear #2864
      polymorphonuclear #2864
      splenocytes #2865
      characterising #2865
      interleukin33 #2869
      rats inbred strains #2869
      cyanogen bromide #2874
      disease characterized #2875
      guillain #2875
      cells cd8 #2881
      periodontitis #2882
      parvalbumin #2884
      reveals #2885
      clone cells #2885
      exacerbate #2888
      igg iga #2891
      migration inhibitory #2892
      costimulatory molecules #2895
      tgfbeta #2895
      innate immune responses #2896
      dce #2896
      antigens class humans #2898
      dq #2905
      antigen hla #2907
      atp synthase #2909
      linked immunosorbent #2911
      enhancement #2911
      studying #2918
      diseases disease #2920
      shortly #2920
      ergometry #2921
      allogenic #2921
      vaccine development #2925
      steadily #2925
      type lectin #2926
      obvious #2927
      ifn γ #2931
      autoimmune disorder #2935
      dextran #2939
      female flow #2943
      expression macrophages #2944
      injections #2944
      ifn gamma #2945
      proteins peptides #2946
      cd68 #2947
      patients antibodies #2949
      interleukin4 #2950
      cells immune #2955
      eventually #2956
      toll receptor #2961
      cell infiltration #2962
      expressions #2963
      calcium ions #2964
      qtl #2965
      suppressed #2967
      histocytochemistry #2967
      hnrnp #2980
      genetics #2982
      ifn response #2985
      cepacia #2988
      antirheumatic agents #2993
      elusive #2994
      hdac #2995
      thymus gland #2997
      swedish #2998
      respective #3000
      lineage commitment #3003
      time points #3009
      indoleamine #3009
      cells female #3010
      innate #3014
      therapeutic strategies #3014
      illustrating #3017
      anthrax #3019
      interferon ifn #3020
      wild type mice #3026
      defensins #3027
      vdr #3031
      accelerating #3033
      lung inflammation #3033
      macrophage migration #3036
      t‐cell #3039
      endo #3039
      synthetic peptides #3040
      appearance #3045
      quinoxalines #3047
      cd8 #3048
      immunomodulator #3050
      model mice #3051
      longterm treatment #3052
      twin studies #3053
      complex traits #3055
      ppt #3058
      interleukin23 #3061
      profound #3067
      sjögren syndrome #3069
      prevailing #3073
      salivary #3076
      mediated immune #3077
      role cell #3078
      beta #3080
      destruction #3082
      model human #3083
      irrespective #3083
      gene expression profiling #3086
      impairing #3087
      nodes #3091
      inhibitory factors #3092
      glutamic #3092
      parvalbumins #3093
      receptor 4 #3098
      inbred balb mice #3098
      genetic deletion #3100
      detailed description #3101
      postpartum period #3107
      germinal #3108
      antirheumatic #3109
      staphylococcus #3114
      type wt #3120
      neuronal cell #3123
      effects treatment #3124
      suspect #3127
      igm igg #3130
      specificity #3131
      glycans #3136
      monoclonal antibody #3137
      psoriasis #3142
      receptors tlrs #3142
      logarithm #3146
      cd4 cd8 #3147
      preformed #3151
      immune systems #3152
      possibility #3153
      cell activity #3154
      propria #3155
      molecule #3155
      cba #3164
      posttranslational modification #3167
      sjogren #3171
      massively #3172
      accumulated #3180
      precedes #3185
      cell specific #3185
      blockage #3187
      tissue specific #3191
      dynorphin #3191
      pertussis toxin #3192
      cells rats #3193
      adult mice #3193
      keratinocytes #3194
      unravel #3199
      reactivity #3202
      helper #3204
      modified #3205
      ovx #3208
      serum levels #3210
      erbeta #3211
      antiinflammatory #3211
      phagosomes #3212
      nitroarginine #3212
      abs #3216
      cells animals #3224
      publication arthritis #3224
      gpi #3226
      chromosome 1 #3237
      class iii #3239
      clarified #3242
      permitting #3246
      macrophage #3247
      collagenous #3247
      lod score #3252
      bacterial antibodies #3254
      backbone #3257
      nonalcoholic steatohepatitis nash #3260
      female gonadal #3263
      treated animals #3264
      acrylic #3265
      chronic inflammatory #3267
      meps #3270
      immunosorbent assay #3272
      implicate #3274
      inflammation interferon #3278
      proteoglycans #3278
      sch #3280
      arthralgia #3283
      nephritis #3283
      gonadal steroid #3284
      normal rats #3287
      abundantly #3289
      models genetic #3298
      igg1 #3298
      immunoglobulin heavy #3303
      erythematosus #3305
      adaptations #3309
      proteins mice #3309
      elicits #3314
      characterise #3314
      blastocyst #3315
      nociception #3316
      absence #3318
      diseases autoimmune #3321
      beta receptors #3325
      publication animals #3325
      mice protein #3327
      anticardiolipin #3328
      confirmed #3329
      gc cells #3331
      serologically #3332
      suppression #3338
      regional lymph nodes #3341
      macromolecular #3343
      clinical phenotypes #3345
      cd62l #3353
      influenced #3355
      trypanosoma #3358
      akr #3371
      vitamin d3 #3373
      editor #3377
      antinuclear antibodies #3382
      sle #3384
      genetic polymorphisms #3385
      ovariectomy #3386
      mechanistic studies #3395
      levels inflammatory #3395
      macroporous #3395
      explains #3396
      mount #3397
      tubercle #3402
      somatic mutations #3406
      receptors transforming #3410
      early phase #3413
      haptens #3413
      positions #3418
      nk cells #3419
      erythematosus systemic #3419
      neutrophil activation #3421
      reacts #3421
      penetrant #3425
      reply #3432
      proving #3434
      receptor type #3434
      dendritic cells #3436
      serum igg #3437
      alleles #3440
      permitted #3441
      cauda #3443
      4 months #3444
      injection #3445
      superoxide production #3446
      protein tyrosine #3447
      obscure #3448
      humans immunization #3448
      increased sensitivity #3449
      antimicrobial peptide #3451
      diffusely #3459
      characterised #3469
      h5n1 #3470
      patients sle #3470
      flow cytometry #3476
      modifying #3477
      multimers #3491
      inflammatory mediators #3491
      proteoglycan #3496
      successes #3497
      il21 #3500
      ly #3501
      elucidate #3503
      classical #3505
      developed #3505
      protein processing #3506
      salivary gland #3507
      publication animals animals #3509
      neutrophilic #3510
      pathobiology #3511
      pathological features #3517
      specific cd4 #3519
      globulins #3526
      267 #3528
      deoxyguanosine #3528
      germline #3529
      phenotypically #3529
      predispose #3532
      lacrimal #3534
      micrometer #3534
      transglutaminases #3535
      radiolabelled #3539
      regulatory cells tregs #3540
      cyclosporins #3540
      mbq #3541
      dominantly #3548
      histological examination #3554
      investigate #3559
      infections staphylococcus #3561
      mast cells #3563
      cultured disease models #3568
      socs1 #3570
      humans interferon #3571
      histological #3574
      homogenate #3576
      interesting #3580
      gamma #3580
      negative patients #3583
      artificially #3584
      role development #3585
      cytolytic #3589
      hindlimb #3590
      il33 #3593
      triggered #3597
      compared wild #3597
      usage #3601
      immunohistochemical staining #3608
      upregulation #3612
      previous findings #3617
      intranasal #3619
      tcr #3622
      potential roles #3624
      cleave #3624
      genetic association #3629
      attenuate #3633
      rp #3633
      mapping chromosomes #3634
      genetic #3637
      valuable #3637
      adhere #3638
      today #3645
      cultured culture media #3651
      allele #3655
      gene deletion #3657
      enhances #3657
      cd4 positive #3659
      exerts #3663
      tolllike receptor #3665
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      Prominent publications by Rikard Holmdahl

      KOL-Index: 15284

      The purpose of the study was to map the dominant T cell epitope of the CB11 sequence of CII in RTlu haplotype rats and to determine if, when used as a synthetic peptide, it would induce tolerance to protect against CIA. A dominant epitope corresponding to residues 184-198 included in the sequence of the CB11 fragment of bovine CII was identified in proliferation assay using peptides in an epitope scanning system using synthetic peptides of 15 amino acids, overlapping by 12 amino acids. ...

      के लिए जाना जाता है Mucosal Tolerance | Synthetic Peptide | Cell Epitope | Cia Cii | Collagen‐induced Arthritis
      KOL-Index: 14658

      An antibody response to defined epitopes located on the triple helical portion of type II collagen (CII) is associated with the development of collagen-induced arthritis (CIA) and rheumatoid arthritis (RA). Monoclonal antibodies to epitopes associated with arthritis, but not antibodies specific for epitopes not associated with arthritis, induce arthritis in mice, the so-called collagen antibody induced arthritis (CAIA) model. We have selected monoclonal IgG antibodies specific for four ...

      के लिए जाना जाता है Collagen Antibody | Induced Arthritis | Monoclonal Antibodies | Mice Inbred | Specific Epitopes
      KOL-Index: 13984

      The Aq major histocompatibility complex (MHC) class II molecule is associated with susceptibility to murine collagen-induced arthritis (CIA), whereas the closely related H-2Ap molecule is not. To understand the molecular basis for this difference, we have analyzed the ability of H-2Aq and H-2Ap molecules (referred to as Aq and Ap) to bind and present collagen type II (CII)-derived glycosylated and non-glycosylated peptides. T cell clones specific for the immunodominant CII 256-270 ...

      के लिए जाना जाता है Collagen‐induced Arthritis | Transgenic Models | Aq Molecule | Structural Basis | C3h Mice
      KOL-Index: 13727

      BACKGROUND: Autoantibodies to cyclic citrullinated peptides (anti-CCP) are present in most patients with rheumatoid arthritis (RA), and associate with HLA-DRB1 shared epitope (SE) alleles.

      OBJECTIVE: To investigate reactivities of anti-CCP to various citrullinated proteins/peptides, which represent potential autoantigens in RA, and to examine the relationship between such antibodies, and their association with genetic variants within HLA-DRB1 SE alleles.

      METHODS: Serum samples from 291 ...

      के लिए जाना जाता है Citrullinated Antigens | Rheumatoid Arthritis | Drb1 Alleles | Ccp Patients | Antibody Reactivities
      KOL-Index: 13726

      Type II collagen-induced arthritis (CIA) in mice is an autoimmune experimental model for rheumatoid arthritis. Susceptibility to CIA is associated with certain major histocompatibility complex class II haplotypes. The two very closely related haplotypes H-2q and H-2p differ in susceptibility to CIA. Only mice of H-2q (DBA/1, B10G strains) but not mice of H-2p-expressing strains (like strain B10P) develop CIA and an autoimmune response to type II collagen (CII) after immunization with ...

      के लिए जाना जाता है Mice Cia | Beta Chain | Rheumatoid Arthritis | H2q Haplotype | Type Collagen Cii
      KOL-Index: 13513

      INTRODUCTION: It has previously been shown that an increased number of antibodies against citrullinated peptides/proteins (ACPA) predate the onset of rheumatoid arthritis (RA). Over time antibody positivity expands, involving more specific responses when approaching the onset of symptoms. We investigated the impact of human leukocyte antigen-shared epitope (HLA-SE) alleles and smoking on the development of ACPA, as well as in combination with ACPA during the state of quiescent ...

      के लिए जाना जाता है Citrullinated Peptides | Onset Symptoms | Development Rheumatoid Arthritis | Combination Acpa | Hlase Smoking
      KOL-Index: 13230

      OBJECTIVE: High titers of specific anti-citrullinated protein antibodies (ACPAs) are frequently present in the serum of rheumatoid arthritis (RA) patients, but their presence in synovial fluid is less well characterized. The purpose of this study was to compare the levels of antibody to 4 well-defined citrullinated candidate RA autoantigens in serum and synovial fluid and to determine whether antibodies to one citrullinated antigen are dominant over another. Furthermore, we studied their ...

      के लिए जाना जाता है Citrullinated Antigens | Synovial Fluid | Rheumatoid Arthritis Patients | Type Collagen | Antibodies Acpas
      KOL-Index: 12913

      INTRODUCTION: Toll-like receptors (TLRs) are involved in both innate and adaptive immune responses and are likely to play a complex role in the pathogenesis of human rheumatoid arthritis (RA) and experimental arthritis. The objective of this study was to identify the key TLR in pristane-induced arthritis (PIA), a rat model for RA, and to clarify its roles in the initiation and maintenance of arthritis.

      METHODS: Arthritis in DA rats was induced by pristane and the severity was evaluated ...

      के लिए जाना जाता है Induced Arthritis | Tlr3 Expression | Rats Pristane | Receptor 3 | Inbred Strains Severity
      KOL-Index: 12776

      Multiple sclerosis (MS) is a complex chronic neurologic disease with a suspected autoimmune pathogenesis1,2. Although there is evidence that the development of MS is determined by both environmental influences and genes, these factors are largely undefined3,4, except for major histocompatibility (MHC) genes. Linkage analyses and association studies have shown that susceptibility to MS is associated with genes in the human histocompatibility leukocyte antigens (HLA) class II region, but ...

      के लिए जाना जाता है Multiple Sclerosis | Transgenic Mice | Hla Dr2 | Humanized Model | Spontaneous Disease
      KOL-Index: 12721

      Polymorphism of the major histocompatibility complex (MHC) influences susceptibility to experimental autoimmune encephalomyelitis (EAE) induced by myelin basic protein (MBP) in rats. Current concepts relate such influences to the capacity of class II molecules to present relevant peptides to autoreactive T cells. We have here analyzed the MHC influence on the immune response and the development of EAE after immunization with the immunodominant peptide MBP-63-88. Analysis of MHC-congenic ...

      के लिए जाना जाता है Myelin Basic Protein | Experimental Autoimmune | Major Histocompatibility | Rats Eae | Immune Response
      KOL-Index: 12691

      OBJECTIVE: The presence of antibodies against cyclic citrullinated peptides has been demonstrated to precede the onset of symptoms of rheumatoid arthritis (RA) by several years. The aim of this study was to analyze antibodies against 10 citrullinated autoantigen-derived peptides for reactivity before the onset of RA symptoms.

      METHODS: A case-control study was conducted within the Medical Biobank of Northern Sweden. The study was performed in 409 individuals, 386 of whom donated 717 blood ...

      के लिए जाना जाता है Citrullinated Peptides | Rheumatoid Arthritis | Onset Symptoms | Antibodies Cep1 | Type Collagen
      KOL-Index: 12510

      Antibodies against type II collagen (anti-CII) are arthritogenic and have a crucial role in the initiation of collagen-induced arthritis. Here, we have determined the dependence of T and B cells in collagen-antibody-induced arthritis (CAIA) during different phases of arthritis. Mice deficient for B and/or T cells were susceptible to the CAIA, showing that the antibodies induce arthritis even in the absence of an adaptive immune system. To determine whether CII-reactive T cells could have ...

      के लिए जाना जाता है Collagen Type | Arthritis Mice | Antigen Tcell | Antibodies Cii | Adaptive Immune
      KOL-Index: 12427

      The nonobese diabetic (NOD) mouse spontaneously develops autoimmune-mediated diseases such as diabetes and Sjögren's syndrome. To investigate whether NOD genes also promote autoimmune-mediated arthritis we established a NOD strain with an MHC class II fragment containing the A(q) class II gene predisposing for collagen induced arthritis (NOD.Q). However, this mouse was resistant to arthritis in contrast to other A(q) expressing strains such as B10.Q and DBA/1. To determine the major ...

      के लिए जाना जाता है Genetic Control | Complement Factor | Induced Arthritis | Locus Chromosome | Mice Inbred

      के लिए प्रमुख लोग Rheumatoid Arthritis

      दुनिया में शीर्ष kols
      #1
      Paul Emery
      rheumatoid arthritis ankylosing spondylitis radiographic progression
      #2
      Josef Sebastian Smolen
      rheumatoid arthritis systemic lupus erythematosus radiographic progression
      #3
      James F Fries
      rheumatoid arthritis physical function systemic lupus erythematosus
      #4
      John Turner Sharp
      rheumatoid arthritis radiographic progression joint space width
      #5
      Frederick J Wolfe
      rheumatoid arthritis work disability rheumatic diseases
      #6
      Matthew H Liang
      rheumatoid arthritis systemic lupus erythematosus lyme disease
      एक खोज वाक्यांश का चयन करें   rheumatoid arthritis , rheumatoid arthritis patients , rheumatoid arthritis treatment , rheumatoid arthritis risk , rheumatoid arthritis study

      Rikard Holmdahl:विशेषज्ञ प्रभाव

      जिसके लिए अवधारणाएंRikard Holmdahlप्रत्यक्ष प्रभाव है:Rheumatoid arthritis,  Induced arthritis,  Experimental arthritis,  Collagen type,  Type collagen,  Animal models,  Reactive oxygen species,  Autoimmune diseases.

      Rikard Holmdahl:कोल इम्पैक्ट

      अन्य लेखकों के काम से संबंधित अवधारणाएं जिनके लिएfor which Rikard Holmdahl प्रभाव है:Rheumatoid arthritis,  Multiple sclerosis,  Autoimmune diseases,  Oxidative stress,  Animal models,  Reactive oxygen species,  Nadph oxidase.


       

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      National and Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China | Medical Inflammation Research, MediCity Research Laboratory, University of Turku, Turku,

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