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    • Justin Pijpe

      Justin Pijpe

      Department of Oral & Maxillofacial Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands | Department of Oral & Maxillofacial Surgery, Special Dental Care and ...



      KOL Resume for Justin Pijpe


      Department of Oral & Maxillofacial Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands


      Catharina Hospital, Eindhoven, The Netherlands


      Department of Oral and Maxillofacial Surgery, Catharina Ziekenhuis, Eindhoven, The Netherlands


      Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, The Netherlands


      Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, Groningen, The Netherlands


      University of Groningen, Groningen, The Netherlands


      Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands


      University Medical Center Groningen, University of Groningen, Groningen, The Netherlands


      Department of Oral and Maxillofacial Surgery


      J. Pijpe, Department of Oral and Maxillofacial Surgery, PO box 30.001, 9700 RB Groningen, The Netherlands. E-mail:

      Department of Oral and Maxillofacial Surgery, University Hospital Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.


      Afd. Mondziekten en Kaakchirurgie, Academisch Ziekenhuis, Postbus 30.001, 9700 RB Groningen.


      Department of Pathology, University Hospital of Groningen, Groningen, The Netherlands


      From the Departments of Pathology, Surgical Oncology, and Medical Oncology, University Hospital Groningen, and Department of Medical Genetics, University of Groningen, Groningen; and Department of Pathology, Free University Hospital, Amsterdam, the Netherlands.



      Justin Pijpe: Influence Statistics

      Sample of concepts for which Justin Pijpe is among the top experts in the world.
      Concept World rank
      bsso distraction osteogenesis #1
      total pink esthetic #2
      esthetic patient #2
      dehiscences higher #2
      stage ridge #2
      one‐stage ridge augmentation #2
      patients sialosis patients #2
      bsso distraction #2
      salivary gland parameters #2
      one‐stage ridge #2
      small mucosal dehiscence #2
      esthetic patient satisfaction #2
      success esthetic #2
      sodium retention syndrome #2
      secondphase surgery #2
      sialosis patients #2
      sialosis patients patients #2
      persisting xerostomia #2
      buccal bony dehiscence #2
      cosmetic facial procedures #2
      patients sodium concentrations #2
      onestage ridge augmentation #2
      dehiscence implant #2
      salivary composition sialochemistry #3
      dehiscences anterior #3
      rates parotid #3
      patients sialosis #4
      cellrelated therapies #4
      ifn alpha cd20 #4
      therapeutic intervention phase #4
      rituximab extended followup #4
      sjögren rituximab #4
      underlying disorder patients #4
      labial biopsy diagnosis #4
      dehiscence higher #4
      severe effects sjögren #4
      sjögren syndrome gain #4
      labial biopsy #4
      parotid biopsy #4
      parotid gland biopsy #4
      antitnfalpha ifn alpha #4
      biological agents antitnfalpha #4
      extended followup safety #4


      Prominent publications by Justin Pijpe

      KOL-Index: 15970

      PURPOSE: Several studies have reported clinical behavior and chemotherapy resistance in leiomyosarcomas, but these studies did not differentiate between soft tissue leiomyosarcomas (LMS) and malignant gastrointestinal stromal tumors (GIST). Multidrug resistance (MDR) has been associated with the expression of P-glycoprotein (P-gp), multidrug resistance protein (MRP(1)), and lung resistance protein (LRP). The aim of the present study was to compare LMS and GIST with respect to clinical ...

      Known for Multidrug Resistance | Patients Gist | Soft Tissue | Malignant Gastrointestinal | Stromal Tumors
      KOL-Index: 10650

      OBJECTIVES: To report the successful use of rituximab on salivary gland immunohistology and function in a patient with Sjogren's syndrome (SS) and associated MALT lymphoma.

      CASE REPORT: The patient was a 42 year old woman with primary SS and associated MALT lymphoma located in the parotid gland and the hard palate. Four infusions of rituximab (375 mg/m(2)) weekly resulted in complete remission of the lymphoma. An incision biopsy of the parotid gland before and after treatment showed ...

      Known for Malt Lymphoma | Salivary Gland | Monoclonal Antibodies | Rituximab Treatment | Sjögren Syndrome
      KOL-Index: 10395

      OBJECTIVE: To investigate the safety and efficacy of B cell depletion treatment of patients with active primary Sjögren's syndrome of short duration (early primary SS) and patients with primary SS and mucosa-associated lymphoid tissue (MALT)-type lymphoma (MALT/primary SS).

      METHODS: Fifteen patients with primary SS were included in this phase II trial. Inclusion criteria for the early primary SS group were B cell hyperactivity (IgG >15 gm/liter), presence of autoantibodies (IgM ...

      Known for Rituximab Treatment | Primary Patients | Monoclonal Antibodies | Salivary Gland | Malttype Lymphoma
      KOL-Index: 10093

      OBJECTIVE: To assess the value of the parotid biopsy as a diagnostic tool for primary Sjögren's syndrome (pSS), and to compare the parotid biopsy and the labial biopsy with regard to diagnostic value and biopsy-related morbidity.

      METHODS: In 15 consecutive patients with pSS and 20 controls, the parotid biopsy was assessed as a diagnostic tool based on the presence of lymphocytic foci, benign lymphoepithelial lesions and lymphoid follicles. These new histological criteria were compared ...

      Known for Labial Biopsy | Parotid Gland | Primary Sjögren | Diagnostic Tool | Focus Score
      KOL-Index: 9568

      BACKGROUND: Salivary gland dysfunction is one of the key manifestations of Sjögren's syndrome.

      OBJECTIVES: (1) To assess prospectively loss of function of individual salivary glands in patients with primary and secondary Sjögren's syndrome in relation to disease duration and use of immunomodulatory drugs. (2) To study changes in sialochemical and laboratory values and subjective complaints over time.

      METHODS: 60 patients with Sjögren's syndrome were included in this study. Whole and ...

      Known for Salivary Gland | Patients Sjögren Syndrome | Disease Duration | Flow Rates | Immunomodulatory Drugs
      KOL-Index: 9469

      OBJECTIVE: To identify a panel of protein and messenger RNA (mRNA) biomarkers in human whole saliva (WS) that may be used in the detection of primary Sjögren's syndrome (SS).

      METHODS: Mass spectrometry and expression microarray profiling were used to identify candidate protein and mRNA biomarkers of primary SS in WS samples. Validation of the discovered mRNA and protein biomarkers was also demonstrated using real-time quantitative polymerase chain reaction and immunoblotting ...

      Known for Primary Patients | Messenger Saliva Sensitivity | Mrna Biomarkers | Saliva Samples | Oral Cavity
      KOL-Index: 8972

      OBJECTIVE: To assess the effect of rituximab (anti-CD20 antibody) therapy on the (immuno)histopathology of parotid tissue in patients with primary Sjögren's syndrome (SS) and the correlation of histologic findings with the flow rate and composition of parotid saliva.

      METHODS: In a phase II study, an incisional parotid biopsy specimen was obtained from 5 patients with primary SS before and 12 weeks after rituximab treatment (4 infusions of 375 mg/m(2)). The relative amount of parotid ...

      Known for Rituximab Treatment | Monoclonal Antibodies | Salivary Gland | Germinal Centers | Flow Rate
      KOL-Index: 7724

      The aim of this study was to compare the postoperative stability of the mandible after a bilateral lengthening procedure, either by bilateral sagittal split osteotomy (BSSO) or distraction osteogenesis (DO). All patients who underwent mandibular advancement surgery between March 2001 and June 2004 were evaluated. There were 17 patients in the BSSO group and 18 patients in the DO group. The decision to use intra-oral distraction or BSSO for mandibular advancement primarily depended on the ...

      Known for Mandibular Advancement | Distraction Osteogenesis | Split Osteotomy | Bilateral Sagittal | Postoperative Stability
      KOL-Index: 7511

      OBJECTIVE: To retrospectively analyze the clinical course of patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma of the parotid gland and associated Sjögren's syndrome (SS).

      METHODS: All consecutive patients with SS and MALT lymphoma (MALT-SS) diagnosed in the University Medical Center Groningen between January 1997 and January 2009 were analyzed. Clinical course and treatment outcome of SS and MALT lymphoma were evaluated.

      RESULTS: From a total of 329 patients with SS, ...

      Known for Malt Lymphoma | Parotid Gland | Lymphoid Tissue | 1 Patient | Sjögren Syndrome
      KOL-Index: 4721

      This study assessed salivary gland parameters and clinical data in patients referred to our clinic because of persisting xerostomia of unknown origin, in order to facilitate early diagnosis and recognition of the underlying disorder. Most patients were referred for diagnostic analysis of a possible Sjögren's syndrome (SS). A complete diagnostic work-up was available in all patients (n = 176), including data on salivary gland function, saliva composition, sialography, salivary gland ...

      Known for Salivary Gland | Clinical Data | Nonparametric Surveys | Patients Xerostomia | Saliva Composition
      KOL-Index: 4537

      Over the past decade, facial cosmetic procedures have become more commonplace in dentistry and oral and maxillofacial surgery. An increasing number of patients seek minimal invasive procedures. One of the most requested procedures is treatment with botulinum toxin type A (BoNTA). Treatment of dynamic rhytids and lines with BoNTA is effective and produces high rates of improvement with rapid onset and long duration of action (longer than 4 months for some patients) compared with placebo. ...

      Known for Botulinum Toxin Type | Cosmetic Facial Procedures | Gummy Smile | Glabellar Lines | Facial Areas
      KOL-Index: 3820

      The aim of this study was to estimate the accuracy and reproducibility of citric-acid-stimulated parotid saliva sampling. In healthy volunteers a strong correlation (r2 = 0.79) between flow rates from the left and right parotid gland was observed. In patients with Sjögren's syndrome this correlation (r2 = 0.90) was even stronger. The intraindividual variation in healthy volunteers was 23.3 +/- 5.9%. Increasing the number of collections did not reduce this variation significantly. In head ...

      Known for Flow Rate | Parotid Saliva | Sjögrens Syndrome | Neck Neoplasms Humans | Female Head
      KOL-Index: 3752

      OBJECTIVES: To compare two ridge preservation techniques and spontaneous healing in terms of hard and soft tissue changes 2 months after tooth extraction.

      MATERIAL AND METHODS: The study was designed as a randomized controlled trial and included 75 patients. After single tooth extraction in the maxillary incisor/premolar area, patients were randomly allocated to one of the following groups: (a) ridge preservation with a xenogeneic bone substitute covered with a collagen matrix ...

      Known for Ridge Preservation | Implant Placement | Tooth Extraction | Spontaneous Healing | Clinical Trial
      KOL-Index: 3752
      Known for Monoclonal Antibodies | Primary Sjögren Syndrome | Sjögren Rituximab | Murine Derived | Immunosuppressive Agents

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      Justin Pijpe:Expert Impact

      Concepts for whichJustin Pijpehas direct influence:Rituximab treatment,  Labial biopsy,  Malt lymphoma,  Parotid gland,  Parotid glands,  Systemic diseases,  Implant placement,  Systemic disease.

      Justin Pijpe:KOL impact

      Concepts related to the work of other authors for whichfor which Justin Pijpe has influence:Sjögren syndrome,  Salivary glands,  Autoimmune diseases,  Gastrointestinal stromal tumors,  Pss patients,  Parotid gland,  Monoclonal antibodies.



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      Department of Oral & Maxillofacial Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands | Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Center, Rotterdam, The Netherlands | C

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